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31. 发明授权

US07447408B2 Imaging system and related techniques 有权
标题翻译：成像系统及相关技术
公开(公告)号：US07447408B2
公开(公告)日：2008-11-04
申请号：US11174425
申请日：2005-07-01
申请人： Brett E. Bouma , Guillermo J. Tearney , Dvir Yelin
发明人： Brett E. Bouma , Guillermo J. Tearney , Dvir Yelin
IPC分类号： G02B6/02 , G01J3/00 , G01J3/40 , G01B9/02
CPC分类号： G01N21/474 , G01N21/47 , G02B6/02 , G02B6/02042 , G02B6/036 , G02B6/03605 , G02B6/03622 , G02B6/03638 , G02B6/4298 , G02B23/2469 , G02B23/26 , G02B26/10 , G02B27/48
摘要： A method and apparatus for imaging using a double-clad fiber is described.
摘要翻译：描述了使用双包层光纤进行成像的方法和装置。

32. 发明申请

US20060241585A1 Method of and system for selective cell destruction 失效
标题翻译：选择性细胞破坏的方法和系统
公开(公告)号：US20060241585A1
公开(公告)日：2006-10-26
申请号：US10562001
申请日：2004-06-09
申请人： Yaron Silberberg , Dvir Yelin , Dan Oron
发明人： Yaron Silberberg , Dvir Yelin , Dan Oron
IPC分类号： A61B18/18
CPC分类号： A61B18/20 , A61B18/22
摘要： Method and apparatus for the ionization of living cells where an optical device (14) delivers an optical pulse having an optical field power which is modified locally by an optical field power modifying means (18) to effect ionization and destruction of living cells (16).
摘要翻译：用于使细胞电离的方法和装置，其中光学装置（14）递送具有光场功率的光脉冲，该光脉冲由光场功率调节装置（18）局部修改以实现活细胞（16）的电离和破坏，。

33. 发明授权

US09968245B2 Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s) 有权
公开(公告)号：US09968245B2
公开(公告)日：2018-05-15
申请号：US13614459
申请日：2012-09-13
申请人： Guillermo J. Tearney , Brett Eugene Bouma , Dvir Yelin
发明人： Guillermo J. Tearney , Brett Eugene Bouma , Dvir Yelin
IPC分类号： A61B1/07 , A61B5/00 , A61B18/22 , A61B17/00
CPC分类号： A61B1/07 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B18/22 , A61B2017/00061
摘要： Exemplary apparatus and process can be provided for imaging information associated with at least one portion of a sample. For example, (i) first different wavelengths of at least one first electro-magnetic radiation can be provided within a first wavelength range provided on the portion of the sample so as to determine at least one first transverse location of the portion, and (ii) second different wavelengths of at least one second electro-magnetic radiation within a second wavelength range can be provided on the portion so as to determine at least one second transverse location of the portion. The first and second ranges can east partially overlap on the portion. Further, a relative phase between at least one third electro-magnetic radiation electro-magnetic radiation being returned from the sample and at least one fourth electro-magnetic radiation returned from a reference can be obtained to determine a relative depth location of the portion.

34. 发明授权

US09254089B2 Apparatus and methods for facilitating at least partial overlap of dispersed ration on at least one sample 有权
标题翻译：用于促进至少一个样品上的分散比例的至少部分重叠的装置和方法
公开(公告)号：US09254089B2
公开(公告)日：2016-02-09
申请号：US13054015
申请日：2009-07-14
申请人： Guillermo J. Tearney , Brett Eugene Bouma , Dvir Yelin , Dongkyun Kang
发明人： Guillermo J. Tearney , Brett Eugene Bouma , Dvir Yelin , Dongkyun Kang
IPC分类号： G01J3/02 , A61B5/00 , G01N21/47 , G02B23/24 , G01J3/18
CPC分类号： A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G01J3/0218 , G01J3/0256 , G01J3/18 , G01N21/4795 , G02B23/2423 , G02B23/2469
摘要： Exemplary embodiments of apparatus and method according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. The exemplary apparatus can include a first arrangement having at least two wave-guides which can be configured to provide there through at least two respective electromagnetic radiations with at least partially different wavelengths from one another. The exemplary apparatus can also include a dispersive second arrangement structured to receive the electro-magnetic radiations and forward at least two dispersed radiations associated with the respective electro-magnetic radiations to at least one section of the structure. The wave-guide(s) can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate at least partially overlap of the dispersed radiations on the structure. In addition, another arrangement can be provided which can include at least two further wave-guides which can be configured to receive the electro-magnetic radiations from the dispersive arrangement. Each of the further wave-guides can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate a receipt of a different one of the such electro-magnetic radiations as a function of wavelengths thereof.
摘要翻译：提供了根据本公开的设备和方法的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。示例性装置可以包括具有至少两个波导的第一装置，所述至少两个波导可被配置成通过至少两个具有彼此具有至少部分不同波长的相应电磁辐射来提供波导。示例性装置还可以包括分散第二装置，其被构造为接收电磁辐射，并将与各个电磁辐射相关联的至少两个分散的辐射转发到该结构的至少一个部分。波导可以相对于分散布置被构造和/或空间布置，以促进结构上分散的辐射的至少部分重叠。此外，可以提供另外的布置，其可以包括至少两个另外的波导，其可被配置为从分散布置接收电磁辐射。每个其它波导可以相对于色散装置构造和/或空间布置，以便于接收这样的电磁辐射中不同的一个作为其波长的函数。

35. 发明授权

US08812087B2 Method and system of spectrally encoded imaging 有权
标题翻译：频谱编码成像的方法和系统
公开(公告)号：US08812087B2
公开(公告)日：2014-08-19
申请号：US12816395
申请日：2010-06-16
申请人： Dvir Yelin , Avraham Abramov
发明人： Dvir Yelin , Avraham Abramov
IPC分类号： A61B6/00
CPC分类号： A61B1/07 , A61B1/00163 , A61B5/0084 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/024 , G01J3/0256 , G01J3/2823 , G01N21/55 , G01N21/645 , G01N2021/6417 , G01N2021/6484 , G01N2201/084
摘要： A spectrally encoded imaging device having a light transmission path arrangement which propagates light to illuminate a target object, a light collection path arrangement having a light collection waveguide which propagates a spectrally encoded portion of the light from the target object to a detector which forms an image of the target object accordingly, and a diffractive element which spectrally disperses at least one of the light and the spectrally encoded portion. The light transmission path arrangement and the light collection path arrangement are optically isolated from one another.
摘要翻译：具有传播光以照射目标物体的光传输路径布置的光谱编码成像装置，具有将来自目标物体的光的光谱编码部分传播到形成图像的检测器的光收集波导的光收集路径装置以及对光和频谱编码部分中的至少一个进行光谱分散的衍射元件。光传输路径布置和光采集路径布置彼此光学隔离。

36. 发明授权

US08780176B2 Vessel imaging system and method 有权
标题翻译：血管成像系统及方法
公开(公告)号：US08780176B2
公开(公告)日：2014-07-15
申请号：US12461558
申请日：2009-08-17
申请人： Dvir Yelin
发明人： Dvir Yelin
IPC分类号： H04N13/00 , A61B1/04 , H04N15/00
CPC分类号： A61B1/043 , A61B1/00096 , A61B1/00165 , A61B1/05 , A61B1/06 , A61B1/07 , A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/14546 , A61B5/418 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/10 , G01J3/44 , G01J3/443 , G01N21/64 , G01N21/65 , G01N2021/653 , H04N5/2256
摘要： A system and a method for acquiring an image of a particle flowing in a vessel, the system comprising a light source for generating an illuminating light, an imaging probe for laterally statically illuminating at least a portion of said vessel with the illuminating light, a detection unit for detecting emitted light from an illuminated portion of said particle, and a processor unit for reproducing an image of the illuminated portion of said particle from the emitted light.
摘要翻译：一种用于获取在容器中流动的颗粒的图像的系统和方法，所述系统包括用于产生照明光的光源，用于使用所述照明光横向地静态照射所述容器的一部分的成像探针，用于检测来自所述颗粒的照射部分的发射光的单元，以及用于从所发射的光再现所述颗粒的照射部分的图像的处理器单元。

37. 发明申请

US20110273718A1 IMAGING SYSTEM AND RELATED TECHNIQUES 有权
标题翻译：成像系统及相关技术
公开(公告)号：US20110273718A1
公开(公告)日：2011-11-10
申请号：US13084344
申请日：2011-04-11
申请人： Brett E. Bouma , Guillermo J. Tearney , Dvir Yelin
发明人： Brett E. Bouma , Guillermo J. Tearney , Dvir Yelin
IPC分类号： G01N21/47 , G02B6/02
CPC分类号： G01N21/474 , G01N21/47 , G02B6/02 , G02B6/02042 , G02B6/036 , G02B6/03605 , G02B6/03622 , G02B6/03638 , G02B6/4298 , G02B23/2469 , G02B23/26 , G02B26/10 , G02B27/48
摘要： A method and apparatus for imaging using a double-clad fiber is described.
摘要翻译：描述了使用双包层光纤进行成像的方法和装置。

38. 发明申请

US20110237892A1 APPARATUS AND METHODS FOR COLOR ENDOSCOPY 有权
标题翻译：颜色内窥镜的装置和方法
公开(公告)号：US20110237892A1
公开(公告)日：2011-09-29
申请号：US13054015
申请日：2009-07-14
申请人： Guillermo J. Tearney , Brett Eugene Bouma , Dvir Yelin , Dongkyun Kang
发明人： Guillermo J. Tearney , Brett Eugene Bouma , Dvir Yelin , Dongkyun Kang
IPC分类号： A61B1/06
CPC分类号： A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G01J3/0218 , G01J3/0256 , G01J3/18 , G01N21/4795 , G02B23/2423 , G02B23/2469
摘要： Exemplary embodiments of apparatus and method according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. The exemplary apparatus can include a first arrangement having at least two wave-guides which can be configured to provide there through at least two respective electro-magnetic radiations with at least partially different wavelengths from one another. The exemplary apparatus can also include a dispersive second arrangement structured to receive the electro-magnetic radiations and forward at least two dispersed radiations associated with the respective electro-magnetic radiations to at least one section of the structure. The wave-guide(s) can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate at least partially overlap of the dispersed radiations on the structure. In addition, another arrangement can be provided which can include at least two further wave-guides which can be configured to receive the electro-magnetic radiations from the dispersive arrangement. Each of the further wave-guides can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate a receipt of a different one of the such electro-magnetic radiations as a function of wavelengths thereof.
摘要翻译：提供了根据本公开的设备和方法的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。示例性装置可以包括具有至少两个波导的第一装置，所述至少两个波导可以被配置成通过至少两个彼此具有至少部分不同波长的相应的电磁辐射来提供它们。示例性装置还可以包括分散第二装置，其被构造为接收电磁辐射，并将与各个电磁辐射相关联的至少两个分散的辐射转发到该结构的至少一个部分。波导可以相对于分散布置被构造和/或空间布置，以促进结构上分散的辐射的至少部分重叠。此外，可以提供另外的布置，其可以包括至少两个另外的波导，其可被配置为从分散布置接收电磁辐射。每个其它波导可以相对于色散装置构造和/或空间布置，以便于接收这样的电磁辐射中不同的一个作为其波长的函数。

39. 发明申请

US20110144504A1 METHOD AND APPARATUS FOR OPTICAL IMAGING VIA SPECTRAL ENCODING 有权
标题翻译：通过光谱编码进行光学成像的方法和装置
公开(公告)号：US20110144504A1
公开(公告)日：2011-06-16
申请号：US12946635
申请日：2010-11-15
申请人： Guillermo J. Tearney , Dvir Yelin , Brett Eugene Bouma
发明人： Guillermo J. Tearney , Dvir Yelin , Brett Eugene Bouma
IPC分类号： A61B6/00
CPC分类号： G01N33/4833 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6852 , G01B9/02 , G01B9/02027 , G01B9/02049 , G01B9/02064 , G01B9/02087 , G01B9/02091 , G01B9/04 , G01N21/25 , G01N21/27 , G01N21/4795 , G01N21/6458 , G01N21/6486 , G01N23/046 , G01N2021/1765 , G01N2223/419 , G02B21/0028 , G02B23/2423 , G02B23/243 , G02B23/2461 , G02B23/2476
摘要： Method, apparatus and arrangement according an exemplary embodiment of the present invention can be provided for generating an image of at least one portion of an anatomical structure. For example, the portion can have an area greater than about 1 mm2, and the image can have a resolution a transverse resolution that is below about 10 μm. For example, light can be scanned over such portion so as to generate first information which is related to the portion, where the light may be provided through a diffraction arrangement to generate a spectrally dispersed line. Method, apparatus and arrangement according to a further exemplary embodiment of the present invention can be provided for positioning a radiation or optical beam within an anatomical structure based on signals generated by scanning a portion of the structure using the same or a different beam.
摘要翻译：可以提供根据本发明的示例性实施例的方法，装置和装置，用于生成解剖结构的至少一部分的图像。例如，该部分可以具有大于约1mm 2的面积，并且图像可以具有低于约10μm的横向分辨率的分辨率。例如，可以在这样的部分上扫描光，以便产生与该部分相关的第一信息，其中可以通过衍射装置提供光以产生光谱分散的线。可以提供根据本发明的另一示例性实施例的方法，装置和装置，用于基于通过使用相同或不同的束扫描结构的一部分而产生的信号来将辐射或光束定位在解剖结构内。

40. 发明授权

US07925133B2 Imaging system and related techniques 有权
标题翻译：成像系统及相关技术
公开(公告)号：US07925133B2
公开(公告)日：2011-04-12
申请号：US12205758
申请日：2008-09-05
申请人： Brett E. Bouma , Guillermo J. Tearney , Dvir Yelin
发明人： Brett E. Bouma , Guillermo J. Tearney , Dvir Yelin
IPC分类号： G02B6/036 , G02B6/02
CPC分类号： G01N21/474 , G01N21/47 , G02B6/02 , G02B6/02042 , G02B6/036 , G02B6/03605 , G02B6/03622 , G02B6/03638 , G02B6/4298 , G02B23/2469 , G02B23/26 , G02B26/10 , G02B27/48
摘要： A method and apparatus for imaging using a double-clad fiber is described.
摘要翻译：描述了使用双包层光纤进行成像的方法和装置。

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