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31. 发明授权

US06632243B1 Body fluid flow control device 有权
标题翻译：体液流量控制装置
公开(公告)号：US06632243B1
公开(公告)日：2003-10-14
申请号：US09397218
申请日：1999-09-16
申请人： Gholam-Reza Zadno-Azizi , John S. Ford , April Marano-Ford
发明人： Gholam-Reza Zadno-Azizi , John S. Ford , April Marano-Ford
IPC分类号： A61F206
CPC分类号： A61F2/2418 , A61F2/0009 , A61F2/0022 , A61F2/2475 , A61F2/88 , A61F2/91 , A61F2/958 , A61F2210/0033
摘要： A device to provide body fluid flow control in the form of a valve to be located within a duct or passageway. The device is controlled through pressure above a preselected threshold. Bulk resilience about a passageway in a valve body provides the mechanism for controlled flow. One-way valve operation may be provided through a flap or through a pressure differential on the valve body depending upon the direction of flow. A frame structure positioned within a resilient seal includes longitudinally elongate elements which may be of spring material, malleable material or heat recoverable material so as to accomplish an initial insertion state and an expanded anchoring state. A valve support transitions between the resilient seal portion and the valve body to insure that the states do not change the threshold opening pressure. Insertion devices may be employed to position and actuate a change of state of the frame in the body duct or passageway.
摘要翻译：用于提供阀门形式的体液流量控制的装置，其位于管道或通道内。该设备通过高于预选阈值的压力进行控制。关于阀体中的通道的大体积弹性提供了用于受控流动的机构。可以根据流动方向通过挡板或通过阀体上的压差来提供单向阀操作。定位在弹性密封件内的框架结构包括纵向细长的元件，其可以是弹簧材料，可延展材料或可热回收材料，以便实现初始插入状态和扩张锚定状态。阀支撑件在弹性密封部分和阀体之间过渡以确保状态不改变阈值开启压力。可以使用插入装置来定位和致动框架在体导管或通道中的状态变化。

32. 发明授权

US08187325B2 Materials for use in accommodating intraocular lens system 有权
标题翻译：用于容纳眼内透镜系统的材料
公开(公告)号：US08187325B2
公开(公告)日：2012-05-29
申请号：US11406821
申请日：2006-04-19
申请人： Gholam-Reza Zadno-Azizi , Tuan Anh Nguyen
发明人： Gholam-Reza Zadno-Azizi , Tuan Anh Nguyen
IPC分类号： A61F2/16
CPC分类号： A61F2/1648 , A61F2/1629 , B29D11/023 , B29D11/026
摘要： There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.
摘要翻译：公开了一种用于植入具有光轴的眼睛中的适应性眼内透镜。透镜包括前部，前部又包括前部观察元件和前部偏置元件。透镜还包括后部，后部又包括与前视觉元件间隔开的后视元件和后偏置元件。前部和后部在眼内透镜的第一和第二顶点相交。前部和后部和/或顶点响应于其上的力而导致观察元件之间的分离改变。还公开了另外的实施例和方法。

33. 发明申请

US20110282441A1 INTRAOCULAR LENS WITH POST-IMPLANTATION ADJUSTMENT CAPABILITIES 有权
标题翻译：具有后植入调整能力的内窥镜
公开(公告)号：US20110282441A1
公开(公告)日：2011-11-17
申请号：US13175091
申请日：2011-07-01
申请人： Gholam-Reza Zadno-Azizi
发明人： Gholam-Reza Zadno-Azizi
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1627 , A61F2/1629 , A61F2/1648 , A61F2250/0001 , A61F2250/0004
摘要： Disclosed are accommodating intraocular lenses for implantation in an eye having an optical axis. In certain embodiments, an intraocular lens includes an anterior optic, a posterior optic, and a support structure configured to move the optics relative to each other along an optical axis between an accommodated state and an unaccommodated state. In certain embodiments, at least a portion of the support structure can be modified in situ to alter reaction forces between the support structure and at least one structure of the eye. In certain embodiments, a refractive property of one of the anterior or posterior optics can be modified in situ while leaving the refractive properties of the remaining one of the anterior or posterior optics substantially unaffected. Additional embodiments and methods are also disclosed.
摘要翻译：公开了用于植入眼睛中的眼内透镜，其具有光轴。在某些实施例中，眼内透镜包括前光学元件，后光学元件和支撑结构，其被配置为沿着容纳状态和未调节状态之间的光轴相对于彼此移动光学元件。在某些实施方案中，支撑结构的至少一部分可以原位改性以改变支撑结构与眼睛的至少一种结构之间的反作用力。在某些实施例中，前光学器件或后光学器件中的一个的折射性能可以在原位进行修改，同时保留前光学元件或后光镜中的剩余光学部件的折射特性基本上不受影响。还公开了另外的实施例和方法。

34. 发明授权

US07087080B2 Materials for use in intraocular lens system 有权
公开(公告)号：US07087080B2
公开(公告)日：2006-08-08
申请号：US10021797
申请日：2001-12-11
申请人： Gholam-Reza Zadno-Azizi , Erica J. Rogers , Tuan Anh Nguyen , Albert C. Ting
发明人： Gholam-Reza Zadno-Azizi , Erica J. Rogers , Tuan Anh Nguyen , Albert C. Ting
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/15 , A61F2/1629 , A61F2/1648 , B29D11/023 , B29D11/026 , Y10S623/907
摘要： There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

35. 发明授权

US07041134B2 Hydraulic configuration for intraocular lens system 有权
公开(公告)号：US07041134B2
公开(公告)日：2006-05-09
申请号：US10877513
申请日：2004-06-25
申请人： Tuan Anh Nguyen , Valdemar Portney , Gholam-Reza Zadno-Azizi , Albert C. Ting
发明人： Tuan Anh Nguyen , Valdemar Portney , Gholam-Reza Zadno-Azizi , Albert C. Ting
IPC分类号： A61F2/14
CPC分类号： A61F2/1613 , A61F2/15 , A61F2/1629 , A61F2/1648 , B29D11/023 , B29D11/026 , Y10S623/907
摘要： There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

36. 发明申请

US20050267575A1 Accommodating intraocular lens system with aberration-enhanced performance 有权
标题翻译：适应具有像差增强性能的人工晶状体系统
公开(公告)号：US20050267575A1
公开(公告)日：2005-12-01
申请号：US11195422
申请日：2005-08-01
申请人： Tuan Nguyen , Gholam-Reza Zadno-Azizi , Scott Evans , Valedmar Portney
发明人： Tuan Nguyen , Gholam-Reza Zadno-Azizi , Scott Evans , Valedmar Portney
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1627 , A61F2/1629 , A61F2/1632 , A61F2/1648
摘要： An accommodating intraocular lens implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power. The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power. The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.
摘要翻译：可植入眼中的适应性眼内透镜。透镜包括具有前偏置元件的前部和具有屈光力的前光学元件。透镜还包括具有后偏置元件的后部部分和具有屈光力的后视镜。前视神经和后视镜相对于睫状肌的作用相对移动以改变光学元件与透镜屈光力之间的分离。透镜具有约70mg至约115mg的像差诱导力特征，以允许当透镜在眼睛中时像差引起的光学元件的相对运动，从而增加透镜的光学像差，从而增加透镜的焦深的光学像差。在一个变型中，透镜具有70mg至115mg的像差诱导力特征。还公开了相关方法。

37. 发明申请

US20050234547A1 Intraocular lens 有权
标题翻译：人工晶状体
公开(公告)号：US20050234547A1
公开(公告)日：2005-10-20
申请号：US10958871
申请日：2004-10-05
申请人： Tuan Nguyen , Gholam-Reza Zadno-Azizi , Scott Evans
发明人： Tuan Nguyen , Gholam-Reza Zadno-Azizi , Scott Evans
IPC分类号： A61F2/16
CPC分类号： A61F2/1616 , A61F2/1629 , A61F2/1648
摘要： An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.
摘要翻译：容纳人工晶状体具有前部，其包括前部观察元件和连接到前部观察元件的前部偏置元件。后部具有后观察元件和连接到后视元件的后偏置元件。前和后偏置元件在第一和第二顶点连接。第一和第二扩张构件连接到后部。第一和第二扩张构件延伸到显着前后观察元件前侧的位置。

38. 发明申请

US20050055092A1 Hydraulic configuration for intraocular lens system 有权
标题翻译：眼内透镜系统液压配置
公开(公告)号：US20050055092A1
公开(公告)日：2005-03-10
申请号：US10877513
申请日：2004-06-25
申请人： Tuan Nguyen , Valdemar Portney , Gholam-Reza Zadno-Azizi , Albert Ting
发明人： Tuan Nguyen , Valdemar Portney , Gholam-Reza Zadno-Azizi , Albert Ting
IPC分类号： A61F2/16 , B29D11/02
CPC分类号： A61F2/1613 , A61F2/15 , A61F2/1629 , A61F2/1648 , B29D11/023 , B29D11/026 , Y10S623/907
摘要： There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.
摘要翻译：公开了一种用于植入具有光轴的眼睛中的适应性眼内透镜。透镜包括前部，前部又包括前部观察元件和前部偏置元件。透镜还包括后部，后部又包括与前视觉元件间隔开的后视元件和后偏置元件。前部和后部在眼内透镜的第一和第二顶点相交。前部和后部和/或顶点响应于其上的力而导致观察元件之间的分离改变。还公开了另外的实施例和方法。

39. 发明授权

US06786934B2 Biasing element for intraocular lens system 有权
标题翻译：眼内透镜系统的偏压元件
公开(公告)号：US06786934B2
公开(公告)日：2004-09-07
申请号：US10020858
申请日：2001-12-11
申请人： Gholam-Reza Zadno-Azizi , Tuan Anh Nguyen , Albert C. Ting , Valdemar Portney
发明人： Gholam-Reza Zadno-Azizi , Tuan Anh Nguyen , Albert C. Ting , Valdemar Portney
IPC分类号： A61F216
CPC分类号： A61F2/1613 , A61F2/15 , A61F2/1629 , A61F2/1648 , B29D11/023 , B29D11/026 , Y10S623/907
摘要： There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens has an anterior portion which in turn includes an anterior viewing element and an anterior biasing element. The lens also has a posterior portion which in turn includes a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.
摘要翻译：公开了一种用于植入具有光轴的眼睛中的适应性眼内透镜。透镜具有前部，该前部又包括前部观察元件和前部偏置元件。透镜还具有后部，该后部又包括与前部观察元件间隔开的后部观察元件和后部偏置元件。前部和后部在眼内透镜的第一和第二顶点相交。前部和后部和/或顶点响应于其上的力而导致观察元件之间的分离改变。还公开了另外的实施例和方法。

40. 发明授权

US06761737B2 Translation member for intraocular lens system 有权
标题翻译：眼内透镜系统翻译会员
公开(公告)号：US06761737B2
公开(公告)日：2004-07-13
申请号：US10017915
申请日：2001-12-11
申请人： Gholam-Reza Zadno-Azizi , Tuan Anh Nguyen , Valdemar Portney , Albert C. Ting
发明人： Gholam-Reza Zadno-Azizi , Tuan Anh Nguyen , Valdemar Portney , Albert C. Ting
IPC分类号： A61F214
CPC分类号： A61F2/1613 , A61F2/15 , A61F2/1629 , A61F2/1648 , B29D11/023 , B29D11/026 , Y10S623/907
摘要： There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.
摘要翻译：公开了一种用于植入具有光轴的眼睛中的适应性眼内透镜。透镜包括前部，前部又包括前部观察元件和前部偏置元件。透镜还包括后部，后部又包括与前视觉元件间隔开的后视元件和后偏置元件。前部和后部在眼内透镜的第一和第二顶点相交。前部和后部和/或顶点响应于其上的力而导致观察元件之间的分离改变。还公开了另外的实施例和方法。

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