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31. 发明授权

US08016795B2 Device for oral administration of a medicine 有权
标题翻译：用于口服药物的装置
公开(公告)号：US08016795B2
公开(公告)日：2011-09-13
申请号：US10569145
申请日：2004-08-12
申请人： Laurent Barrelle , Frederic Perot , Catherine Felix-Faure
发明人： Laurent Barrelle , Frederic Perot , Catherine Felix-Faure
IPC分类号： A61M5/00
CPC分类号： A61J7/0053 , A61M5/1782 , A61M5/284 , A61M5/344 , A61M2005/3139
摘要： An assembly for oral administration of a medicinal product to be reconstituted from an active principle in dry or liquid form and from a diluent, A device including a prefilled syringe with said diluent, able by itself to receive a parenteral injection member is provided. A support including a body of elongate form is fastened to the syringe, the support includes a device for fixing to the syringe and, at its distal end a device for preventing the connecting of the needle to the tip of the syringe. A bottle including the active principle and a system for transferring the diluent to the active principle, then the reconstituted medicinal product from the bottle to the syringe, the transfer system being separate from the support.
摘要翻译：一种用于口服给药的药物组合物，其用于从干燥或液体形式的活性成分和稀释剂中重构。包括具有所述稀释剂的预充式注射器的装置本身可以容纳胃肠外注射部件。包括细长形状体的支撑件被固定到注射器，支撑件包括用于固定到注射器的装置，并且在其远端处具有用于防止针连接到注射器的尖端的装置。包括活性成分的瓶子和用于将稀释剂转移到活性成分的系统，然后从瓶子到注射器的重新配制的药物产品，转移系统与支持体分开。

32. 发明申请

US20110218500A1 AUTOMATIC INJECTION DEVICE WITH AUDIBLE INDICATOR OF COMPLETED INJECTION 有权
标题翻译：自动注射装置与完整注射器的可视指示器
公开(公告)号：US20110218500A1
公开(公告)日：2011-09-08
申请号：US13121201
申请日：2008-09-29
申请人： Guillaume Grunhut , Frederic Perot , Samuel Gagnieux , Romain Lanier , Yves Enfoux
发明人： Guillaume Grunhut , Frederic Perot , Samuel Gagnieux , Romain Lanier , Yves Enfoux
IPC分类号： A61M5/315
CPC分类号： A61M5/2033 , A61M5/31511 , A61M5/3157 , A61M2005/206 , A61M2205/581
摘要： The present invention relates to a device (1) for automatic injection comprising a container (2), a piston (8) and: a piston rod (9) coupled to said piston (8) during the injection, biasing means (18) for causing distal movement of said piston rod (9) with respect to said container (2), a housing (14; 214) receiving said container (2), said piston rod (9) and said biasing means (18), controlling means (13, 22) for producing an audible indicator at the end of injection, characterized in that: said controlling means comprise one first element (13), flexible or breakable and coupled to said housing (14), or to said piston rod (9), during the injection, and one second element (22), coupled to said piston rod (9), or to said housing (14), during the injection, said first and second elements cooperating with each other at the end of injection under the effect of the said biasing means (18) to produce said audible indicator.
摘要翻译：本发明涉及一种用于自动喷射的装置（1），其包括容器（2），活塞（8）和：在注射期间联接到所述活塞（8）的活塞杆（9），偏压装置（18）引起所述活塞杆（9）相对于所述容器（2）的远端运动，容纳所述容器（2）的壳体（14; 214），所述活塞杆（9）和所述偏置装置（18），控制装置 13，22），用于在注射结束时产生可听指示器，其特征在于：所述控制装置包括柔性或可断裂并联接到所述壳体（14）或所述活塞杆（9）的一个第一元件（13），以及在注射期间连接到所述活塞杆（9）的一个第二元件（22）或所述壳体（14），所述第一和第二元件在注射结束时在彼此协作所述偏置装置（18）的作用产生所述可听指示器。

33. 发明授权

US07967010B2 Spray or injection device allowing at least two preset doses of product to be delivered 有权
标题翻译：喷雾或注射装置允许至少两个预设剂量的产品被输送
公开(公告)号：US07967010B2
公开(公告)日：2011-06-28
申请号：US12690159
申请日：2010-01-20
申请人： Lionel Vedrine , Frederic Perot , Laurent Barrelle
发明人： Lionel Vedrine , Frederic Perot , Laurent Barrelle
IPC分类号： B05B7/00 , B05B11/00
CPC分类号： A61M5/2429 , A61M5/2459 , A61M5/315 , A61M5/31595 , A61M11/007 , A61M11/06 , A61M15/0065 , A61M15/08 , B05B11/02 , B05B11/025
摘要： A spray or injection device that includes a casing or a pusher that includes at least one tab radially moveable between a first radial position, in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position and then allow it to return to the first radial position. The pusher or the casing further includes at least one stop between the pusher and casing to delineate the end of a first stroke corresponding to a first dose of medicament, and the beginning of a second stroke corresponding to a second dose of medicament.
摘要翻译：一种喷雾或注射装置，其包括外壳或推动器，其包括至少一个突出部，其可在第一径向位置和第二径向位置之间径向移动，所述突片在第一径向位置之间，其中突片不阻碍推动器相对于外壳的移动，该卡舌反对推动器的移动。推动器或壳体分别包括至少一个斜面形突起，其被构造成使突片进入第二径向位置，然后允许其返回到第一径向位置。推动器或套管还包括推动器和套管之间的至少一个止动件，以描绘对应于第一剂量的药物的第一冲程的结束，以及对应于第二剂量的药物的第二冲程的开始。

34. 发明申请

US20110118701A1 Dose Dividing Delivery Device 审中-公开
标题翻译：剂量分拣装置
公开(公告)号：US20110118701A1
公开(公告)日：2011-05-19
申请号：US12864685
申请日：2008-01-30
申请人： Bruno Baney , Colin May , Patrick Dupuis , Frederic Perot
发明人： Bruno Baney , Colin May , Patrick Dupuis , Frederic Perot
IPC分类号： A61M5/315
CPC分类号： A61M5/31526 , A61M5/3134 , A61M5/31528 , A61M5/31595 , A61M5/3243 , A61M5/3293
摘要： A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing the plunger. The plunger (30) has features which divide the dose into discrete intervals. As the plunger is moved during delivery, features on the plunger and features connected to the barrel interact to provide for intermittent stops to the injection process. Other aspects of the device provide-for reduced dead space, safety and selective interconnection with other devices. Thus, the delivery device divides the dose.
摘要翻译：提供了一种简单的方法和设备，可实现来自储存器的单位剂量。将剂量吸入储存器中，然后通过按压柱塞从装置中排出。柱塞（30）具有将剂量分成离散间隔的特征。当柱塞在输送期间移动时，柱塞上的特征和连接到筒的特征相互作用以提供喷射过程的间歇停止。该设备的其他方面提供了减少的死空间，安全性和与其他设备的选择性互连。因此，递送装置分配剂量。

35. 发明授权

US07875007B2 Syringe accessory 有权
标题翻译：注射器配件
公开(公告)号：US07875007B2
公开(公告)日：2011-01-25
申请号：US10520980
申请日：2003-07-10
申请人： Frederic Perot , Lionel Vedrine
发明人： Frederic Perot , Lionel Vedrine
IPC分类号： A61M5/00 , A61M5/31
CPC分类号： A61M5/344 , A61F9/0017 , A61M2005/3139
摘要： According to the invention, the accessory (1) comprises a body (15) of roughly semi-tubular shape, first means of holding the syringe comprising a distal transverse wall (20) connected to one end of said body (15), and pierced with a hole (22) for the passage of the needle (7) through it, and second means of holding the syringe comprising a bearing zone (61) against which the proximal flange (10) or the lateral lugs that the syringe body (5) comprises is or are intended to bear so as to provide support for the user's fingers; the distance between said distal transverse wall (20) and said bearing zone (61) is such that the adapter (8) connecting the needle (7) to the syringe body (5) is kept bearing against said distal transverse wall (20) when said flange (10) or said lateral lugs are bearing against said bearing zone (61).
摘要翻译：根据本发明，附件（1）包括大致半管形的主体（15），第一装置保持注射器，其包括连接到所述主体（15）的一端的远侧横向壁（20）具有用于针（7）通过其的通孔（22），以及保持注射器的第二装置，其包括轴承区（61），近侧凸缘（10）或侧向凸耳与注射器主体（5））包括或旨在承担以便为用户的手指提供支持; 所述远端横向壁（20）和所述支承区域（61）之间的距离使得将针（7）连接到注射器主体（5）的适配器（8）保持抵靠所述远侧横向壁（20）所述凸缘（10）或所述侧向凸耳与所述轴承区（61）相对。

36. 发明申请

US20110015577A1 INJECTION DEVICE WITH RETRACTABLE NEEDLE 有权
标题翻译：具有可回缩针的注射装置
公开(公告)号：US20110015577A1
公开(公告)日：2011-01-20
申请号：US12298647
申请日：2007-04-26
申请人： Bruno Baney , Frederic Perot , Kevin David Neale
发明人： Bruno Baney , Frederic Perot , Kevin David Neale
IPC分类号： A61M5/32
CPC分类号： A61M5/3234 , A61M5/508
摘要： The present invention relates to a needle assembly (1) to be used in combination with a storing device (200) comprising a barrel (8) defining a chamber (9) receiving a product (4) and a piston (2), the assembly (1) comprising: —needle-bearing portion (7) in a first material, movable between an exposed and a retracted positions of the needle (5), —engaging means (8a, 10, 11, 18,) for securing said needle-bearing portion (7) to said barrel (8) in the exposed position, characterized in that it comprises: —sealing means (15) in a second material for tightly sealing the distal end (9a) of said chamber (9) to said needle-bearing portion (7), —a breakable portion (7a) located between said engaging means (8a, 10, 11, 18,) and said needle-bearing portion (7), which, when broken, allows independent proximal displacement of said needle-bearing portion (7) relative to said engaging means (8a, 10, 11, 18,) between said exposed and said retracted positions, said first material being more rigid than said second material. The invention also relates to an injection device (100) comprising said needle assembly (1) and a storing device (200).
摘要翻译：本发明涉及一种与包括限定容纳产品（4）和活塞（2）的室（9）的桶（8））的存储装置（200）组合使用的针组件（1），所述组件（1）包括：在第一材料中的可携带轴承部分（7），其可在针（5）的暴露位置和缩回位置之间移动，用于固定所述针头（5）的注入装置（8a，10,11,18）（7）到暴露位置的所述筒体（8），其特征在于，它包括： - 用于将所述腔室（9）的远端（9a）紧密地密封到所述腔室（9）的第二材料的密封装置（15）滚针轴承部分（7）， - 位于所述接合装置（8a，10,11,18）和所述滚针轴承部分（7）之间的可破坏部分（7a），当断裂时，允许独立的近侧位移所述滚针轴承部分（7）相对于所述接合装置（8a，10,11,18）在所述暴露和所述缩回位置之间，所述第一材料是更多钻机 id比所述第二材料。本发明还涉及包括所述针组件（1）和存储装置（200）的注射装置（100）。

37. 发明申请

US20100140130A1 STACKABLE PACKAGING UNIT 有权
标题翻译：可堆叠包装单元
公开(公告)号：US20100140130A1
公开(公告)日：2010-06-10
申请号：US12514373
申请日：2007-11-14
申请人： Frederic Perot
发明人： Frederic Perot
IPC分类号： B65D85/62
CPC分类号： B65D21/083 , Y10S229/918
摘要： The present invention pertains to a stackable packaging unit (1) for the packaging of products (100), the said packaging unit (1) comprising at least one encircling wall (2) provided at least with a corner ridge (3) dividing it into at least two retaining panels (2a) Partially folded down towards one another about the said corner ridge (3) so as to hold the said products (100) to be packaged, at least one end of the said corner ridge (3) being connected to the corresponding edges of the said retaining panels (2a) by at least one inclined centring profile. The stackable packaging unit (1) also comprises an intermediate element. The invention also pertains to a packaging comprising at least one such packaging unit (1).
摘要翻译：本发明涉及用于包装产品（100）的可堆叠包装单元（1），所述包装单元（1）包括至少一个环形壁（2），至少设置有将其分为至少两个保持板（2a）围绕所述拐角脊部（3）朝向彼此部分地向下折叠，以便将所述产品（100）保持被包装，所述拐角脊（3）的至少一端被连接通过至少一个倾斜的定心轮廓到达所述保持面板（2a）的相应边缘。可堆叠包装单元（1）还包括中间元件。本发明还涉及包括至少一个这种包装单元（1）的包装。

38. 发明申请

US20070250017A1 Pre-Filled Syringe with Anti-Tamper Cap 有权
标题翻译：带防篡改帽的预充注射器
公开(公告)号：US20070250017A1
公开(公告)日：2007-10-25
申请号：US10556617
申请日：2004-05-25
申请人： Franck Carred , Frederic Perot , Laurent Barrelle
发明人： Franck Carred , Frederic Perot , Laurent Barrelle
IPC分类号： A61M5/315
CPC分类号： A61M5/31501 , A61M5/31505 , A61M5/31511 , A61M5/50 , A61M2005/3139
摘要： The present invention relates to a device (1) for medical use, of the prefilled ready-to-use syringe type, comprising a tubular body (2) comprising, at its distal end (4), a tip (5) to take a needle and, at its proximal end (12), a flange (13), a piston (3) able to slide inside the tubular body (2) and arranged in an initial position defining, with the tubular body (2), an internal working volume (8) at least partially filled with a medicinal liquid (9), a rod (11) for actuating the piston extending beyond the proximal end of the tubular body, characterized in that a rigid cover (15) is attached and fixed in a definitive way to the flange (13) and has a central opening (23) for the free translational passage of the actuating rod (11), and the said cover (15) forms or comprises means of stopping the actuating rod (11) in the proximal direction, and in that a plug (14) is arranged to translate freely in the tubular body (2) between the piston (3) and the proximal end (12) of the said body, said plug (14) being made of material resistant to puncturing with a needle.
摘要翻译：本发明涉及一种用于医疗用途的预充式即用型注射器类型的装置（1），其包括管状体（2），其在其远端（4）包括尖端（5）针，并且在其近端（12）处具有凸缘（13），能够在管状体（2）内滑动并且布置在与管状体（2）限定的初始位置的内部的活塞（3）至少部分地填充有药用液体（9）的工作容积（8）;用于致动所述活塞的杆（11），其延伸超过所述管状体的近端，其特征在于，刚性盖（15）附接并固定在（13）的确定方式并且具有用于致动杆（11）的自由平移通道的中心开口（23），并且所述盖（15）形成或包括将致动杆（11）停止在其中的装置近端方向，并且插头（14）布置成在活塞（3）之间的管状体（2）中自由平移，和所述主体的近端（12），所述插头（14）由耐刺穿针的材料制成。

39. 发明申请

US20070083164A1 Device for oral administration of a medicine 有权
标题翻译：用于口服药物的装置
公开(公告)号：US20070083164A1
公开(公告)日：2007-04-12
申请号：US10569145
申请日：2004-08-12
申请人： Laurent Barrelle , Frederic Perot , Catherine Felix-Faure
发明人： Laurent Barrelle , Frederic Perot , Catherine Felix-Faure
IPC分类号： A61M5/00
CPC分类号： A61J7/0053 , A61M5/1782 , A61M5/284 , A61M5/344 , A61M2005/3139
摘要： The present invention pertains to an assembly for oral administration of a medicinal product to be reconstituted from an active principle (50) in dry or liquid form and from a diluent, characterized in that it comprises: i) a device (1) comprising: a prefilled syringe (2) with said diluent, able by itself to receive a parenteral injection member, a support (3) comprising a body (18) of elongate form which is fastened to the syringe (2), said support comprising at its proximal end (19) means (21) for fixing to the syringe (2) and, at its distal end (20), one means (24) for preventing the connecting of the parenteral injection member to the tip of the syringe (2), ii) a bottle comprising the active principle and iii) a system for transferring the diluent to the active principle, then the reconstituted medicinal product from the bottle to the syringe (2), said transfer system being separate from the support (3).
摘要翻译：本发明涉及一种用于口服给药的药物组合物，其由干燥或液体形式的活性成分（50）和稀释剂组成，其特征在于其包括：i）装置（1），其包含：预充式注射器（2）与所述稀释剂本身能够接收肠胃外注射部件;支撑件（3），其包括紧固到注射器（2）的细长形式的主体（18），所述支撑件包括在其近端（19）用于固定到注射器（2）的装置（21）和在其远端（20）处的一个用于防止肠胃外注射构件与注射器（2）的尖端连接的装置（24），ii ）一种包含活性成分的瓶子，和iii）用于将稀释剂转移到活性成分的系统，然后从瓶子到注射器（2）将复原的药物产品，所述转运系统与支持体（3）分开。

40. 发明授权

US06629963B2 Syringe and needle shield assembly and method of sterilizing such assembly 有权
标题翻译：注射器和针罩组件以及灭菌方法
公开(公告)号：US06629963B2
公开(公告)日：2003-10-07
申请号：US09809469
申请日：2001-03-15
申请人： A. Wesley Prais , Judith L. Doyle , Steven L. Koziol , Frederic Perot
发明人： A. Wesley Prais , Judith L. Doyle , Steven L. Koziol , Frederic Perot
IPC分类号： A61M532
CPC分类号： B24B19/16 , A61M5/3202 , A61M5/3286 , A61M2005/3109 , A61M2205/195
摘要： A syringe assembly including a needle cannula having a five-beveled point and a needle shield formed of a styrene block poly(ethylene/butylene) thermoplastic elastomer which significantly reduces needle penetration force and may reduce the cycle time for gas sterilization. The multi-beveled needle cannula point includes a primary bevel, a pair of tip bevels and a pair of middle bevels each intermediate the primary bevel and a respective tip bevel, wherein the angles of rotation of the primary bevel and the intermediate bevels are substantially equal resulting in reduced heights of intercepts between the bevels, thereby reducing needle penetration force. The needle shield maintains the sharpness of the needle cannula during application, sterilization and removal of the shield and it is believed that the needle shield will also reduce the cycle time of gas sterilization as compared to rubber needle shields and vulcanizate thermoplastic elastomers.
摘要翻译：一种注射器组件，其包括具有五斜面的针插管和由苯乙烯嵌段聚（乙烯/丁烯）热塑性弹性体形成的针护罩，其显着降低针穿刺力并且可减少气体灭菌的循环时间。所述多角针插管点包括主斜面，一对尖端斜面和一对中间斜面，每个中间斜面均在所述主斜面和相应的尖端斜面之间，其中所述主斜面和所述中间斜面的旋转角度基本相等导致斜面之间的截距的高度减小，从而减少针的穿透力。针护罩在施加，消毒和除去护罩期间保持针管的清晰度，并且相信与橡胶针护罩和硫化橡胶热塑性弹性体相比，针罩还将减少气体灭菌的循环时间。

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