专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US08343478B2 Parapoxviruses in combination with other antiviral agents for the treatment of viral diseases 有权
标题翻译：副抗病毒药物与其他抗病毒药物联合用于治疗病毒性疾病
公开(公告)号：US08343478B2
公开(公告)日：2013-01-01
申请号：US11652937
申请日：2007-01-11
申请人： Daniela Paulsen , Helga Ruebsamen-Schaeff , Amar Kureishi , Gerhard Hunsmann , Christiane Stahl-Hennig , Andreas Meyerhans , Alexandra Schuetz , Olaf Weber
发明人： Daniela Paulsen , Helga Ruebsamen-Schaeff , Amar Kureishi , Gerhard Hunsmann , Christiane Stahl-Hennig , Andreas Meyerhans , Alexandra Schuetz , Olaf Weber
IPC分类号： A61K39/155 , A61K31/711 , A61K38/00
CPC分类号： A61K45/06 , A61K31/70 , A61K35/76 , C12N2710/24232 , C12N2740/15011 , C12N2740/16011 , A61K2300/00
摘要： The present invention relates to the use of Parapoxviruses in combination with other agents for the treatment of viral diseases, and in particular HIV infections and AIDS. The invention also relates to methods for producing medicaments based on combinations of Parapoxviruses and other antiviral agents, and to such medicaments. In particular, the invention relates to the use of Parapoxviruses in combination with agents of the kind used for antiretroviral therapy and highly active antiretroviral therapy (HAART).
摘要翻译：本发明涉及与其它药剂组合用于治疗病毒性疾病，特别是HIV感染和AIDS的副作用病毒的用途。本发明还涉及基于对痘病毒和其它抗病毒剂的组合制备药物的方法以及这些药物。特别地，本发明涉及副作用病毒与用于抗逆转录病毒治疗和高活性抗逆转录病毒治疗（HAART）的药物的组合的使用。

32. 发明申请

US20110061625A1 EXHAUST THROTTLE-EGR VALVE MODULE FOR A DIESEL ENGINE 审中-公开
标题翻译：用于柴油发动机的排气节流阀模块
公开(公告)号：US20110061625A1
公开(公告)日：2011-03-17
申请号：US12620543
申请日：2009-11-17
申请人： Volker Joergl , Timm Kiener , Olaf Weber , Bruce Thorpe
发明人： Volker Joergl , Timm Kiener , Olaf Weber , Bruce Thorpe
IPC分类号： F01L7/00
CPC分类号： F02M26/16 , F02B29/0406 , F02M26/06 , F02M26/10 , F02M26/15 , F02M26/23 , F02M26/35 , F02M26/53 , F02M26/54 , F02M26/71 , Y10T137/86855 , Y10T137/86871
摘要： A valve assembly for use in an air management assembly having an engine, an exhaust side, and an intake side, where the valve assembly provides a housing, a plurality of openings in the housing, a valve in the housing, and an actuator operably connected to the valve. The housing is in fluid communication with the exhaust side and the intake side. The plurality of openings in the housing form at least one inlet and at least one outlet in the housing. The valve moves with respect to the plurality of openings.
摘要翻译：一种用于具有发动机，排气侧和进气侧的空气管理组件的阀组件，其中阀组件提供壳体，壳体中的多个开口，壳体中的阀和可操作地连接的致动器到阀门。外壳与排气侧和进气侧流体连通。壳体中的多个开口形成壳体中的至少一个入口和至少一个出口。阀相对于多个开口移动。

33. 发明授权

US07757679B2 Integrated charge air and EGR valve 有权
标题翻译：集成增压空气和EGR阀
公开(公告)号：US07757679B2
公开(公告)日：2010-07-20
申请号：US12224414
申请日：2007-03-22
申请人： Volker Joergl , Timm Kiener , Olaf Weber , Robert S. Czarnowski
发明人： Volker Joergl , Timm Kiener , Olaf Weber , Robert S. Czarnowski
IPC分类号： F02B47/08
CPC分类号： F02B29/0418 , F02D2009/0276 , F02M26/05 , F02M26/06 , F02M26/07 , F02M26/15 , F02M26/16 , F02M26/24 , F02M26/26 , F02M26/64 , Y02T10/146
摘要： An engine assembly (10) comprising an engine, a plurality of coolers, a plurality of bypasses, and at least one actuator (32). The engine has an exhaust manifold and an intake manifold. The gaseous fluid exiting the exhaust manifold is recirculated to the intake manifold. The exhaust gas passes through either an air cooler or a bypass. At least one actuator is operably connected to the plurality of bypasses. The bypasses have a valve (28, 30) which is actuated to control the flow of the gaseous fluid through the bypass as both the bypass and the cooler. Therefore, when a single actuator is used to control the valves in both bypasses, the valves in the bypasses have the same relationship with the inlets so that a single actuator movement will control both valves in the same manner.
摘要翻译：包括发动机，多个冷却器，多个旁路以及至少一个致动器（32）的发动机组件（10）。发动机具有排气歧管和进气歧管。离开排气歧管的气体流体再循环到进气歧管。废气通过空气冷却器或旁路。至少一个致动器可操作地连接到多个旁路。旁路具有阀（28,30），其被致动以控制气体流体通过旁路作为旁路和冷却器的流动。因此，当使用单个致动器来控制两个旁路中的阀时，旁路中的阀与入口具有相同的关系，使得单个致动器运动将以相同的方式控制两个阀。

34. 发明申请

US20100129321A1 DIARYL UREA FOR TREATING VIRUS INFECTIONS 审中-公开
标题翻译：用于治疗病毒感染的二尿法
公开(公告)号：US20100129321A1
公开(公告)日：2010-05-27
申请号：US12086454
申请日：2006-12-06
申请人： Olaf Weber , Bernd Riedl
发明人： Olaf Weber , Bernd Riedl
IPC分类号： A61K31/44 , C07D213/81 , A61K31/513 , A61K31/662 , A61K38/16 , A61K31/551 , A61K31/4745 , A61K31/52 , A61K31/522 , A61K31/675 , A61K31/4439 , A61K31/536 , A61K31/472 , A61K31/4725 , A61K31/496 , A61K31/7072 , A61K31/7068 , A61K31/708 , A61K35/76 , A61K36/71 , A61K38/14 , A61K38/21 , A61K31/56 , A61P31/12
CPC分类号： A61K31/44 , A61K31/496 , A61K45/06 , A61K2300/00
摘要： The present invention relates to pharmaceutical compositions for treating virus infections and/or diseases caused thereby comprising 4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide optionally combined with at least one additional therapeutic agent.
摘要翻译：本发明涉及用于治疗由此引起的病毒感染和/或疾病的药物组合物，其包含4 {4- [3-（4-氯-3-三氟甲基苯基） - 脲基] -3-氟苯氧基} - 吡啶-2-甲酸甲基酰胺任选地与至少一种另外的治疗剂组合。

35. 发明申请

US20100125073A1 BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL IN THE TREATMENT OF CANCERS OF THE CENTRAL NERVOUS SYSTEM 审中-公开
标题翻译：用于治疗中枢神经系统癌症的苯唑呋喃和苯并噻吩衍生物
公开(公告)号：US20100125073A1
公开(公告)日：2010-05-20
申请号：US12439062
申请日：2007-08-28
申请人： Olaf Weber , Verena Voehringer , Hans-Georg Lerchen , Frank-Thorsten Hafner , Joerg Keldenich , Karl-Heinz Schlemmer , Ursula Krenz , Bernd Riedl
发明人： Olaf Weber , Verena Voehringer , Hans-Georg Lerchen , Frank-Thorsten Hafner , Joerg Keldenich , Karl-Heinz Schlemmer , Ursula Krenz , Bernd Riedl
IPC分类号： A61K31/5377 , C07D307/82 , A61K31/343 , C07D413/10 , A61K31/422 , A61K31/427 , C07D417/10 , C07D405/10 , A61K31/443 , C07D413/12 , A61P35/00
CPC分类号： A61K31/343 , C07D307/82
摘要： The present invention relates to benzofuran and benzothiophene derivatives and compositions containing such compounds for the production of medicaments for the treatment of cancers of the central nervous system as monotherapy or combination with other agents.
摘要翻译：本发明涉及苯并呋喃和苯并噻吩衍生物和含有这些化合物的组合物，用于制备用于治疗中枢神经系统癌症的药物作为单一疗法或与其它药剂组合。

36. 发明申请

US20090227637A1 DIARYL UREAS FOR TREATING VIRUS INFECTIONS 审中-公开
标题翻译：用于治疗病毒感染的DIARYL UREAS
公开(公告)号：US20090227637A1
公开(公告)日：2009-09-10
申请号：US12097350
申请日：2006-12-06
申请人： Olaf Weber , Bernd Riedl
发明人： Olaf Weber , Bernd Riedl
IPC分类号： A61K31/44 , A61P31/12
CPC分类号： A61K31/44
摘要： The present invention relates to pharmaceutical compositions for treating virus infections and/or diseases caused by virus infections comprising at least a diaryl urea compound optionally combined with at least one additional therapeutic agent. Useful combinations include e.g. BAY 43-9006 as a diaryl urea compound.
摘要翻译：本发明涉及用于治疗由病毒感染引起的病毒感染和/或疾病的药物组合物，其包含任选与至少一种其它治疗剂组合的至少二芳基脲化合物。有用的组合包括例如 BAY 43-9006作为二芳基脲化合物。

37. 发明申请

US20090013978A1 Integrated Charge Air and Egr Valve 有权
标题翻译：集成充气和电磁阀
公开(公告)号：US20090013978A1
公开(公告)日：2009-01-15
申请号：US12224414
申请日：2007-03-22
申请人： Volker Joergl , Timm Kiener , Olaf Weber , Robert S. Czarnowski
发明人： Volker Joergl , Timm Kiener , Olaf Weber , Robert S. Czarnowski
IPC分类号： F02M25/07
CPC分类号： F02B29/0418 , F02D2009/0276 , F02M26/05 , F02M26/06 , F02M26/07 , F02M26/15 , F02M26/16 , F02M26/24 , F02M26/26 , F02M26/64 , Y02T10/146
摘要： An engine assembly (10) comprising an engine, a plurality of coolers, a plurality of bypasses, and at least one actuator (32). The engine has an exhaust manifold and an intake manifold. The gaseous fluid exiting the exhaust manifold is recirculated to the intake manifold. The exhaust gas passes through either an air cooler or a bypass. At least one actuator is operably connected to the plurality of bypasses. The bypasses have a valve (28, 30) which is actuated to control the flow of the gaseous fluid through the bypass as both the bypass and the cooler. Therefore, when a single actuator is used to control the valves in both bypasses, the valves in the bypasses have the same relationship with the inlets so that a single actuator movement will control both valves in the same manner.
摘要翻译：包括发动机，多个冷却器，多个旁路以及至少一个致动器（32）的发动机组件（10）。发动机具有排气歧管和进气歧管。离开排气歧管的气体流体再循环到进气歧管。废气通过空气冷却器或旁路。至少一个致动器可操作地连接到多个旁路。旁路具有阀（28,30），其被致动以控制通过旁路的气态流体作为旁路和冷却器的流动。因此，当使用单个致动器来控制两个旁路中的阀时，旁路中的阀与入口具有相同的关系，使得单个致动器运动将以相同的方式控制两个阀。

38. 发明授权

US07105553B2 Thiazolyl amide derivatives 有权
标题翻译：噻唑基酰胺衍生物
公开(公告)号：US07105553B2
公开(公告)日：2006-09-12
申请号：US10168197
申请日：2000-12-12
申请人： Rüdiger Fischer , Gerald Kleymann , Ulrich Betz , Judith Baumeister , Wolfgang Bender , Peter Eckenberg , Gabriele Handke , Martin Hendrix , Kerstin Henninger , Axel Jensen , Jörg Keldenich , Udo Schneider , Olaf Weber
发明人： Rüdiger Fischer , Gerald Kleymann , Ulrich Betz , Judith Baumeister , Wolfgang Bender , Peter Eckenberg , Gabriele Handke , Martin Hendrix , Kerstin Henninger , Axel Jensen , Jörg Keldenich , Udo Schneider , Olaf Weber
IPC分类号： A61K31/426 , C07D277/54
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/54 , C07D417/12 , C07F7/1804 , C07F9/6539
摘要： The present invention relates to novel compounds, to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.
摘要翻译：本发明涉及新化合物，其制备方法及其用作药物，特别是抗病毒药物。

39. 发明申请

US20060008471A1 Organ, tissue and cell-specific immuno-therapeutic for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and for cancer, based on a recombinant parapox virus 审中-公开
标题翻译：用于慢性病毒感染和炎性，退行性和增殖性疾病，特别是肝脏和癌症的器官，组织和细胞特异性免疫治疗，基于重组旁分泌病毒
公开(公告)号：US20060008471A1
公开(公告)日：2006-01-12
申请号：US11225508
申请日：2005-09-13
申请人： Olaf Weber , Angela Siegling , Tobias Schlapp
发明人： Olaf Weber , Angela Siegling , Tobias Schlapp
IPC分类号： A61K39/12
CPC分类号： C12N15/86 , C12N15/87 , C12N2710/24243
摘要： The present invention relates to the preparation and use of organ-specific, tissue-specific and/or cell-specific recombinant parapoxvirus ovis as a pathogen-specific and organ-specific, targeted immunotherapeutic agent for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and cancer.
摘要翻译：本发明涉及器官特异性，组织特异性和/或细胞特异性重组副痘病毒ovis作为慢性病毒感染和炎性，退行性和增殖性疾病的病原体特异性和器官特异性靶向免疫治疗剂的制备和用途，特别是肝脏和癌症。

40. 发明授权

US06334436B1 Secondary air system for an internal combustion engine 失效
标题翻译：内燃机二次空气系统
公开(公告)号：US06334436B1
公开(公告)日：2002-01-01
申请号：US09677782
申请日：2000-10-02
申请人： Holger Paffrath , Olaf Weber
发明人： Holger Paffrath , Olaf Weber
IPC分类号： F02B3300
CPC分类号： F02D9/02 , F01N3/32 , F02D2009/0283 , Y02T10/20
摘要： A secondary air system 10 is proposed for an internal combustion engine, which has a turbine 11 driven by a pressure gradient in the intake air and a compressor 14 driven by the turbine 11. The turbine is connected by a turbine inlet line 12 and a turbine outlet line 13 to an air intake duct 20. The compressor 14 has a compressor inlet line 15 and a compressor outlet line 16. The cold produced by the turbine 11 is used by a turbine heat exchanger 17 and transport lines 27 for the cooling of, e.g., oil. The heat produced by the compressor 14 is used by a compressor heat exchanger 18 and the transport lines 27 connected thereto, e.g., for heating air.
摘要翻译：提出了一种用于内燃机的二次空气系统10，其具有由进气中的压力梯度驱动的涡轮11和由涡轮11驱动的压缩机14.涡轮机通过涡轮机入口管线12和涡轮机出口管路13连接到进气管道20.压缩机14具有压缩机入口管线15和压缩机出口管线16.由涡轮机11产生的冷却由涡轮机热交换器17和输送管线27用于冷却，例如油。由压缩机14产生的热量由压缩机热交换器18和与其连接的输送线路27使用，例如用于加热空气。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式