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31. 发明申请

US20060259028A1 System for Tissue Ablation 失效
标题翻译：组织消融系统
公开(公告)号：US20060259028A1
公开(公告)日：2006-11-16
申请号：US11420712
申请日：2006-05-26
申请人： David Utley , John Gaiser , Stuart Edwards , Scott West , Jay Qin
发明人： David Utley , John Gaiser , Stuart Edwards , Scott West , Jay Qin
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Systems for treating a mucosal surface of an alimentary canal tissue region are provided. The systems can include an elongate support structure, an expandable member positionable at a distal portion of the support structure and one or more radio frequency (RF) ablation electrodes carried by the expandable member. The elongate support structure and the expandable member can be adapted to place the one or more electrodes in contact with a mucosal surface of an alimentary canal tissue region. The system can further include an RF energy source connected to the one or more electrodes.
摘要翻译：提供了用于治疗消化道组织区域的粘膜表面的系统。该系统可以包括细长的支撑结构，可定位在支撑结构的远端部分处的可扩张构件以及由可扩张构件承载的一个或多个射频（RF）消融电极。细长支撑结构和可扩张构件可适于将一个或多个电极与消化道组织区域的粘膜表面接触。该系统还可以包括连接到一个或多个电极的RF能量源。

32. 发明申请

US20050263160A1 Intraoral aversion devices and methods 有权
标题翻译：口腔内厌恶装置和方法
公开(公告)号：US20050263160A1
公开(公告)日：2005-12-01
申请号：US10943379
申请日：2004-09-17
申请人： David Utley , Jack Utley , Peter Keith , Michael Berman , Robert Atkinson
发明人： David Utley , Jack Utley , Peter Keith , Michael Berman , Robert Atkinson
IPC分类号： A24F47/00
CPC分类号： A24F47/00
摘要： An intraoral aversion device to assist a user in quitting an undesirable behavior such as tobacco smoking, tobacco chewing, use of snuff, illicit drug use, excessive alcohol consumption, excessive food consumption, and/or other undesirable activity facilitated via the mouth. The aversion device may be wholly or partially configured to be disposed in the user's mouth, for example. The aversion device may include a detector and a output device, wherein the detector is configured to detect a parameter indicative of the user engaging in the habit or undesirable activity. If (and only if) the detector detects such a parameter, the output device delivers a negative stimulus to the user, thus providing negative feedback and creating an incentive for the user to limit if not eliminate the undesirable activity.
摘要翻译：口腔厌恶装置，用于帮助用户戒除诸如吸烟，烟草咀嚼，使用鼻烟，非法药物使用，过度饮酒，过度饮食消耗等不良行为和/或通过口促进的其他不良活动等不良行为。例如，厌恶装置可以被全部或部分地配置为设置在使用者的口中。厌恶装置可以包括检测器和输出装置，其中检测器被配置为检测指示用户参与习惯或不期望的活动的参数。如果（且仅当）检测器检测到这样的参数，则输出设备向用户传送负激励，从而提供负反馈并且为用户创造激励以限制如果不消除不期望的活动。

33. 发明申请

US20120089138A1 GERD TREATMENT APPARATUS AND METHOD 审中-公开
标题翻译： GERD治疗装置和方法
公开(公告)号：US20120089138A1
公开(公告)日：2012-04-12
申请号：US13327105
申请日：2011-12-15
申请人： Stuart D. Edwards , David Utley
发明人： Stuart D. Edwards , David Utley
IPC分类号： A61B18/00
CPC分类号： A61B18/1485 , A61B18/00 , A61B18/08 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00867 , A61B2017/22062 , A61B2017/22072 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00839 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/3966 , A61B2218/002 , A61F7/12 , A61M3/0279 , A61M16/0454 , A61M16/0459 , A61M16/0481 , A61M25/1002 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40 , A61N7/02 , C08L2201/12
摘要： An apparatus includes an expandable member. The expandable member is sized to be positionable in a sphincter. An energy delivery device is positioned on a surface of the expandable member. The energy delivery device has a configuration that provides sufficient energy delivery to create lesions in the interior of the sphincter. When the expandable member is removed from the sphincter, the sphincter returns to its closed or contracted configuration.
摘要翻译：一种装置包括可扩张构件。可扩张构件的大小可定位在括约肌中。能量输送装置位于可膨胀构件的表面上。能量输送装置具有提供足够的能量输送以在括约肌内部产生损伤的构造。当可伸缩构件从括约肌中取出时，括约肌返回到其闭合或收缩的构型。

34. 发明申请

US20070135809A1 Precision ablating device 有权
标题翻译：精密烧蚀装置
公开(公告)号：US20070135809A1
公开(公告)日：2007-06-14
申请号：US11286257
申请日：2005-11-23
申请人： David Utley , Robert Garabedian , Michael Wallace
发明人： David Utley , Robert Garabedian , Michael Wallace
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/18 , A61B2018/00214 , A61B2018/0022 , A61B2018/00577 , A61B2018/1495 , A61B2018/1807
摘要： Apparatus for treating abnormal mucosa in an alimentary tract are provided. The apparatus include an ablation structure configured to be removably coupled to an endoscope and a deflection mechanism adapted to move the ablation structure with respect to the endoscope and toward a tissue surface.
摘要翻译：提供了用于治疗消化道异常粘膜的装置。该装置包括被配置为可移除地联接到内窥镜的消融结构和适于使消融结构相对于内窥镜移动并朝向组织表面的偏转机构。

35. 发明申请

US20060015162A1 Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 有权
标题翻译：通过检测和消融胃食管神经和受体来治疗胃反流的方法
公开(公告)号：US20060015162A1
公开(公告)日：2006-01-19
申请号：US11230801
申请日：2005-09-20
申请人： Stuart Edward , John Gaiser , David Utley
发明人： Stuart Edward , John Gaiser , David Utley
IPC分类号： A61F7/00 , A61F7/12
CPC分类号： A61B18/1233 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B2017/00039 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00142 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/00898 , A61B2018/0091 , A61B2018/00982 , A61B2018/0237 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2090/064 , A61B2090/3782 , A61B2218/002 , A61N1/06
摘要： A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity. A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity.
摘要翻译：治疗括约肌的方法提供具有映射电极或治疗电极中的至少一个的括约肌电位映射装置。括约肌电位映射装置被引入至少一部分括约肌，食管下括约肌，胃，贲门或眼底。检测到引起松弛括约肌的生物电活性，并从映射电极或治疗电极传递能量以处理生物电活性。治疗括约肌的方法提供具有映射电极或治疗电极中的至少一个的括约肌电位映射装置。括约肌电位映射装置被引入至少一部分括约肌，食管下括约肌，胃，贲门或眼底。检测到引起松弛括约肌的生物电活性，并从映射电极或治疗电极传递能量以处理生物电活性。

36. 发明申请

US20050159743A1 Method for treating a sphincter 有权
标题翻译：治疗括约肌的方法
公开(公告)号：US20050159743A1
公开(公告)日：2005-07-21
申请号：US11079697
申请日：2005-03-14
申请人： Stuart Edwards , David Utley , Ronald Lax , John Gaiser
发明人： Stuart Edwards , David Utley , Ronald Lax , John Gaiser
IPC分类号： A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18 , A61F7/00 , A61F7/12
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B18/18 , A61B2018/00011 , A61B2018/00029 , A61B2018/00047 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00553 , A61B2018/00666 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2218/002
摘要： A method for treating a sphincter provides a polymer material having a liquid state. The method also provides a catheter having a distal end, a tissue piercing device carried by the distal end, and an energy delivery device coupled to the tissue piercing device. The tissue piercing device has a lumen. The method introduces the catheter into an esophagus and pierces an exterior sphincter tissue surface within with the tissue piercing device. The method advances the tissue piercing device into an interior sphincter tissue site and conveys the polymer material while in a liquid state through the lumen into the interior sphincter tissue site. The method delivers energy to the tissue piercing device to transform the polymer material into a less liquid state within the interior sphincter tissue site, to thereby remodel the sphincter.
摘要翻译：用于治疗括约肌的方法提供具有液体状态的聚合物材料。该方法还提供了具有远端的导管，由远端承载的组织刺穿装置，以及耦合到组织刺穿装置的能量输送装置。组织穿刺装置具有内腔。该方法将导管引入食道并刺穿组织穿刺装置内的外括约肌组织表面。该方法使组织穿刺装置进入内部括约肌组织部位，并将液体状态下的聚合物材料通过内腔输送到内括约肌组织部位。该方法将能量传递到组织刺穿装置，以将聚合物材料转变成内部括约肌组织部位内的较少液体状态，从而改变括约肌。

37. 发明申请

US20050107829A1 Methods for treating the cardia of the stomach 审中-公开
标题翻译：治疗胃贲门的方法
公开(公告)号：US20050107829A1
公开(公告)日：2005-05-19
申请号：US10963025
申请日：2004-10-12
申请人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Qin
发明人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Qin
IPC分类号： A61B18/00 , A61B18/04 , A61B18/12 , A61B18/14 , A61N1/00
CPC分类号： A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Methods treat a tissue region. In one arrangement, the methods deploy an electrode on a support structure in a tissue region at or near the cardia of the stomach. In one embodiment, the support structure has a proximal region and a distal region. The proximal region is enlarged in comparison to the distal region, and the electrode is carried by the enlarged proximal surface. The methods advance the electrode in a path to penetrate the tissue region and couple the electrode to a source of radio frequency energy to ohmically heat tissue and create a lesion in the tissue region.
摘要翻译：方法治疗组织区域。在一种布置中，所述方法将电极部署在胃贲门处或附近的组织区域中的支撑结构上。在一个实施例中，支撑结构具有近端区域和远侧区域。近端区域与远侧区域相比放大，并且电极由扩大的近侧表面承载。所述方法使电极在路径中前进以穿透组织区域并将电极耦合到射频能量源以欧姆加热组织并在组织区域中产生损伤。

38. 发明授权

US06358245B1 Graphical user interface for association with an electrode structure deployed in contact with a tissue region 有权
公开(公告)号：US06358245B1
公开(公告)日：2002-03-19
申请号：US09305123
申请日：1999-05-04
申请人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
发明人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
IPC分类号： A81B1804
CPC分类号： A61B18/1233 , A61B18/12 , A61B18/1206 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00035 , A61B2018/00077 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00488 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007 , Y10S128/922
摘要： Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

39. 发明授权

US06258087B1 Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions 有权
标题翻译：用于形成损伤以治疗括约肌和邻近组织区域功能障碍的可扩展电极组件
公开(公告)号：US06258087B1
公开(公告)日：2001-07-10
申请号：US09304773
申请日：1999-05-04
申请人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
发明人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
IPC分类号： A61B1818
CPC分类号： A61B18/1206 , A61B18/12 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Expandable assemblies for treating a tissue region at or near a sphincter comprises a support basket formed from an array of spines. A mechanism flexes the spines to expand and collapse the basket. Electrodes carried by the spines for advancement in a path to penetrate the tissue region upon expansion of the basket. The basket can be formed from a mechanical array of molded, jointed spines, or from an extruded tube having axial slits forming the spines.
摘要翻译：用于治疗括约肌处或附近的组织区域的可扩展组件包括由脊柱阵列形成的支撑篮。一种机构使脊柱弯曲以使筐膨胀和折叠。由脊柱承载的电极，用于在通过篮子膨胀时穿过组织区域的路径前进。篮子可以由模制的，接合的刺的机械阵列形成，或者由具有形成脊柱的轴向狭缝的挤压管形成。

40. 发明授权

US07462179B2 GERD treatment apparatus and method 失效
标题翻译： GERD治疗仪和方法
公开(公告)号：US07462179B2
公开(公告)日：2008-12-09
申请号：US10986687
申请日：2004-11-12
申请人： Stuart D Edwards , David Utley
发明人： Stuart D Edwards , David Utley
IPC分类号： A61B18/18
CPC分类号： A61B18/1485 , A61B18/00 , A61B18/08 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00867 , A61B2017/22062 , A61B2017/22072 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00839 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/3966 , A61B2218/002 , A61F7/12 , A61M3/0279 , A61M16/0454 , A61M16/0459 , A61M16/0481 , A61M25/1002 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40 , A61N7/02 , C08L2201/12
摘要： An apparatus includes an expandable member. The expandable member is sized to be positionable in a sphincter. An energy delivery device is positioned on a surface of the expandable member. The energy delivery device has a configuration that provides sufficient energy delivery to create lesions in the interior of the sphincter. When the expandable member is removed from the sphincter, the sphincter returns to its closed or contracted configuration.
摘要翻译：一种装置包括可扩张构件。可扩张构件的大小可定位在括约肌中。能量输送装置位于可膨胀构件的表面上。能量输送装置具有提供足够的能量输送以在括约肌内部产生损伤的构造。当可伸缩构件从括约肌中取出时，括约肌返回到其闭合或收缩的构型。

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