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    • 32. 发明授权
    • Defibrillator with impedance-compensated energy delivery
    • 具有阻抗补偿能量输送的除颤器
    • US06241751B1
    • 2001-06-05
    • US09299455
    • 1999-04-22
    • Carlton B. MorganBradford E. GlinerKent W. LeydeThomas D. Lyster
    • Carlton B. MorganBradford E. GlinerKent W. LeydeThomas D. Lyster
    • A61N139
    • A61N1/3943A61N1/39
    • A defibrillator having an energy storage capacitor network with multiple configurations selected according to patient impedance and desired energy level for delivery of an impedance-compensated defibrillation pulse is provided. The set of configurations may include series, parallel, and series/parallel combinations of energy storage capacitors within the energy storage capacitor network. The impedance-compensated defibrillation pulse may be delivered over an expanded range of energy levels while limiting the peak current to levels that are safe for the patient using configurations tailored for lower impedance patients and limiting the range of defibrillation pulse durations and providing adequate current levels for higher impedance patients. Configurations of the energy storage capacitor network may be readily added to extend the range of energy levels well above 200 joules.
    • 提供一种除颤器,其具有根据患者阻抗选择的多种配置的能量存储电容器网络和用于递送阻抗补偿除颤脉冲的期望能量水平。 该组配置可以包括能量存储电容器网络内的能量存储电容器的串联,并联和串联/并联组合。 阻抗补偿的除颤脉冲可以在能量水平的扩展范围内递送,同时将峰值电流限制到对于患者使用适合于较低阻抗患者的配置的安全性的水平,并且限制除颤脉冲持续时间的范围并提供足够的电流水平 阻力较高的患者。 可以容易地添加能量存储电容器网络的配置以扩展远高于200焦耳的能量范围。
    • 34. 发明授权
    • Electrotherapy method and apparatus for external defibrillation
    • 用于外部除颤的电疗方法和装置
    • US5803927A
    • 1998-09-08
    • US824713
    • 1997-02-19
    • David CameronThomas D. LysterDaniel J. PowersBradford E. GlinerClinton S. ColeCarlton B. Morgan
    • David CameronThomas D. LysterDaniel J. PowersBradford E. GlinerClinton S. ColeCarlton B. Morgan
    • A61N1/39
    • A61N1/3937A61N1/3906A61N1/3912
    • An electrotherapy method and apparatus for delivering a multiphasic waveform from an energy source to a patient. The preferred embodiment of the method comprises the steps of charging the energy source to an initial level; discharging the energy source across the electrodes to deliver electrical energy to the patient in a multiphasic waveform; monitoring a patient-dependent electrical parameter during the discharging step; shaping the waveform of the delivered electrical energy based on a value of the monitored electrical parameter, wherein the relative duration of the phases of the multiphasic waveform is dependent on the value of the monitored electrical parameter. The preferred apparatus comprises an energy source; two electrodes adapted to make electrical contact with a patient; a connecting mechanism forming an electrical circuit with the energy source and the electrodes when the electrodes are attached to a patient; and a controller operating the connecting mechanism to deliver electrical energy from the energy source to the electrodes in a multiphasic waveform the relative phase durations of which are based on an electrical parameter monitored during delivery of the electrical energy. The preferred defibrillator apparatus weighs less than 4 pounds and has a volume less than 150 cubic inches, and most preferably, weighs approximately three pounds or less and has a volume of approximately 141 cu.in.
    • 一种用于将多相波形从能量源递送到患者的电疗方法和装置。 该方法的优选实施例包括以下步骤:将能源充电至初始水平; 通过电极排出能量源,以多相波形向患者输送电能; 在放电步骤期间监测与患者相关的电参数; 基于所监测的电参数的值对输送的电能的波形进行整形,其中多相波形的相位的相对持续时间取决于被监测的电参数的值。 优选的装置包括能源; 两个电极,适于与患者进行电接触; 当电极附接到患者时,形成与能量源和电极的电路的连接机构; 以及控制器,其操作所述连接机构,以多相波形将能量从所述能量源传递到所述电极,所述多相波形的相对相位持续时间基于在所述电能传递期间监测的电参数。 优选的除颤器装置重量小于4磅,体积小于150立方英寸,最优选重约3磅或更小,体积约为141立方英寸。
    • 36. 发明授权
    • Method for applying a multiphasic waveform
    • 应用多相波形的方法
    • US5776166A
    • 1998-07-07
    • US803095
    • 1997-02-20
    • Bradford E. GlinerThomas D. LysterClinton S. ColeDaniel J. PowersCarlton B. Morgan
    • Bradford E. GlinerThomas D. LysterClinton S. ColeDaniel J. PowersCarlton B. Morgan
    • A61N1/39
    • A61N1/3937A61N1/3906A61N1/3912
    • This invention provides an external defibrillator and defibrillation method that automatically compensates for patient-to-patient impedance differences in the delivery of electrotherapeutic pulses for defibrillation and cardioversion. In a preferred embodiment, the defibrillator has an energy source that may be discharged through electrodes on the patient to provide a biphasic voltage or current pulse. In one aspect of the invention, the first and second phase duration and initial first phase amplitude are predetermined values. In a second aspect of the invention, the duration of the first phase of the pulse may be extended if the amplitude of the first phase of the pulse fails to fall to a threshold value by the end of the predetermined first phase duration, as might occur with a high impedance patient. In a third aspect of the invention, the first phase ends when the first phase amplitude drops below a threshold value or when the first phase duration reaches a threshold time value, whichever comes first, as might occur with a low to average impedance patient. This method and apparatus of altering the delivered biphasic pulse thereby compensates for patient impedance differences by changing the nature of the delivered electrotherapeutic pulse, resulting in a smaller, more efficient and less expensive defibrillator.
    • 本发明提供一种外部除颤器和除颤方法,其自动补偿用于除颤和心脏复律的电疗脉冲递送中的患者对患者的阻抗差异。 在优选实施例中,除颤器具有能够通过患者身上的电极排出的能量源,以提供双相电压或电流脉冲。 在本发明的一个方面,第一和第二相位持续时间和初始第一相位振幅是预定值。 在本发明的第二方面中,如果脉冲的第一相位的幅度在预定的第一相位持续时间结束时不能下降到阈值,则脉冲的第一相位的持续时间可能会延长 与高阻抗患者。 在本发明的第三方面中,当第一相位幅度下降到低于阈值时或当第一相位持续时间达到阈值时间值(以先到者为准)时,第一相位结束,如同低平均阻抗患者可能发生的那样。 改变输送的双相脉冲的这种方法和装置由此通过改变递送的电疗脉冲的性质来补偿患者的阻抗差异,导致更小,更有效和更便宜的除颤器。
    • 38. 发明授权
    • Method for applying a multiphasic waveform
    • 应用多相波形的方法
    • US5601612A
    • 1997-02-11
    • US601234
    • 1996-02-14
    • Bradford E. GlinerThomas D. LysterClinton S. ColeDaniel J. PowersCarlton B. Morgan
    • Bradford E. GlinerThomas D. LysterClinton S. ColeDaniel J. PowersCarlton B. Morgan
    • A61N1/39
    • A61N1/3937A61N1/3906A61N1/3912
    • This invention provides an external defibrillator and defibrillation method that automatically compensates for patient-to-patient impedance differences in the delivery of electrotherapeutic pulses for defibrillation and cardioversion. In a preferred embodiment, the defibrillator has an energy source that may be discharged through electrodes on the patient to provide a biphasic voltage or current pulse. In one aspect of the invention, the first and second phase duration and initial first phase amplitude are predetermined values. In a second aspect of the invention, the duration of the first phase of the pulse may be extended if the amplitude of the first phase of the pulse fails to fall to a threshold value by the end of the predetermined first phase duration, as might occur with a high impedance patient. In a third aspect of the invention, the first phase ends when the first phase amplitude drops below a threshold value or when the first phase duration reaches a threshold time value, whichever comes first, as might occur with a low to average impedance patient. This method and apparatus of altering the delivered biphasic pulse thereby compensates for patient impedance differences by changing the nature of the delivered electrotherapeutic pulse, resulting in a smaller, more efficient and less expensive defibrillator.
    • 本发明提供一种外部除颤器和除颤方法,其自动补偿用于除颤和心脏复律的电疗脉冲递送中的患者对患者的阻抗差异。 在优选实施例中,除颤器具有能够通过患者身上的电极排出的能量源,以提供双相电压或电流脉冲。 在本发明的一个方面,第一和第二相位持续时间和初始第一相位振幅是预定值。 在本发明的第二方面中,如果在预定的第一相位持续时间结束时脉冲的第一相位的幅度不能下降到阈值,则脉冲的第一相位的持续时间可能会延长 与高阻抗患者。 在本发明的第三方面中,当第一相位幅度下降到低于阈值时或当第一相位持续时间达到阈值时间值(以先到者为准)时,第一相位结束,如同低平均阻抗患者可能发生的那样。 改变输送的双相脉冲的这种方法和装置由此通过改变递送的电疗脉冲的性质来补偿患者的阻抗差异,导致更小,更有效和更便宜的除颤器。
    • 40. 再颁专利
    • Medical electrode and release liner configurations facilitating packaged electrode characterization
    • 医用电极和释放衬垫配置便于封装电极表征
    • USRE43050E1
    • 2011-12-27
    • US11121327
    • 2005-05-02
    • Thomas D. LysterThomas SoloskoCarlton B. MorganKim J. HansenDaniel J. PowersHans Patrick GriesserEric L. JonsenDavid E. Snyder
    • Thomas D. LysterThomas SoloskoCarlton B. MorganKim J. HansenDaniel J. PowersHans Patrick GriesserEric L. JonsenDavid E. Snyder
    • A61N1/04
    • A61N1/0492A61N1/046A61N1/08A61N1/3925A61N2001/37294
    • An electrode includes a conductive adhesive layer and a conductive foil layer having a void therein. One such electrode may be mounted in conjunction with another electrode upon a release liner having one or more openings therein to facilitate electrical signal exchange between electrodes. A release liner may include a moisture permeable and/or moisture absorbent membrane. A release liner may alternatively include a conductive backing layer. A release liner may also include an insulating swatch covering an opening. A release liner may be implemented as a foldable sheet, such that multiple electrodes may be mounted upon the same side of the foldable sheet. A medical device to which the mounted electrodes are coupled may characterize the electrical path between the electrodes. The medical device may perform a variety of electrical measurements, including real and/or complex impedance measurements. Based upon one or more measurements, the medical device may provide an indication of electrode condition, fitness for use, and/or an estimated remaining lifetime. An electrode condition indicator, which may form a portion of the medical device, may generate, present, or display electrode condition and/or estimated remaining lifetime information via a visual metaphor, such as a fuel gauge.
    • 电极包括导电粘合剂层和在其中具有空隙的导电箔层。 一个这样的电极可以与另一电极结合安装在其上具有一个或多个开口的释放衬垫上以便于电极之间的电信号交换。 剥离衬垫可以包括透湿和/或吸湿膜。 替代地,剥离衬垫可以包括导电背衬层。 剥离衬垫还可以包括覆盖开口的绝缘样本。 剥离衬垫可以实现为可折叠片材,使得多个电极可以安装在可折叠片材的同一侧上。 安装的电极被耦合到的医疗装置可以表征电极之间的电路径。 医疗设备可以执行各种电测量,包括实际和/或复阻抗测量。 基于一个或多个测量,医疗设备可以提供电极状态,使用适应性和/或估计的剩余寿命的指示。 可以形成医疗装置的一部分的电极条件指示器可以经由诸如电量计的视觉比喻来生成,呈现或显示电极条件和/或估计的剩余寿命信息。