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    • 31. 发明授权
    • Apparatus for generating an image of moving object
    • 用于产生移动物体的图像的装置
    • US08478014B2
    • 2013-07-02
    • US12990817
    • 2009-05-05
    • Uwe JandtDirk SchaeferMichael Grass
    • Uwe JandtDirk SchaeferMichael Grass
    • G06K9/00
    • G06T11/005G06T7/564G06T2211/412
    • The present invention relates to an apparatus for generating an image of a moving object, wherein a movement of the object comprises a multiple of moving phases. The apparatus comprises a measured detection data providing unit (20) for providing measured detection data of the moving object, which have been detected by using a detection process and which are assigned to the moving phases. The apparatus comprises further a reconstruction unit (13) for reconstructing an image object of the object from the provided measured detection data and an adaptation unit (18) for adapting the image object for different moving phases such that simulated detection data are adapted to the measured detection data of the respective moving phase, wherein the simulated detection data are determined by simulating the detection process, which has been used for detecting the measured detection data assigned to the respective moving phase, with the image object.
    • 本发明涉及一种用于生成移动物体的图像的装置,其中物体的移动包括多个移动相位。 该装置包括测量检测数据提供单元(20),用于提供已经通过使用检测处理检测并被分配给运动相位的移动物体的测量检测数据。 所述设备还包括用于根据所提供的测量的检测数据重建对象的图像对象的重建单元(13)和用于使图像对象适应不同的移动阶段的适配单元(18),使得模拟的检测数据适应于所测量的 检测数据,其中通过模拟已经用于检测分配给各个运动相位的测量检测数据的检测过程与图像对象来确定模拟检测数据。
    • 32. 发明申请
    • 3D-ORIGINATED CARDIAC ROADMAPPING
    • 3D原版CARDIAC ROADMAPPING
    • US20130116551A1
    • 2013-05-09
    • US13810292
    • 2011-07-15
    • Raoul FlorentVincent AuvrayMichael GrassDirk SchaeferGert Schoonenberg
    • Raoul FlorentVincent AuvrayMichael GrassDirk SchaeferGert Schoonenberg
    • A61B6/02
    • A61B6/022A61B6/12A61B6/4441A61B6/463A61B6/487A61B6/504A61B6/5223A61B6/5235A61B2090/364A61B2090/367
    • The present invention relates to 3D-originated cardiac roadmapping. In order to improve the accuracy of the information provided to the user as navigation information, without any additional burden to the patient such as additional X-ray dose, a method is described comprising the steps of a) providing 3D+t image data of a vascular structure of an object; b) acquiring two-dimensional image data of the object, which object comprises the vascular structure, the 2D image data comprising at least one 2D image; c) projecting the vascular structure, thereby generating a plurality of mask images on the basis of a 3D+t image data; d) registering the at least one 2D image with one of the plurality of the mask images, wherein the registration comprises finding the maximum of a similarity factor between the mask images and the at least one 2D image; e) generating a combination of the at least one 2D image and a projection of the vascular structure on the basis of the 3D+t image data according to the registration; and f) displaying the combination as a guiding vessel tree projection. Thus improved cardiac roadmapping in form of a topographical roadmapping is provided since the roadmapping is based on three-dimensional data.
    • 本发明涉及3D起源的心脏路线图。 为了提高作为导航信息提供给用户的信息的准确性,对病人没有任何额外的负担,例如额外的X射线剂量,描述了一种方法,其包括以下步骤:a)提供一个 物体的血管结构; b)获取所述对象的二维图像数据,所述对象包括所述血管结构,所述2D图像数据包括至少一个2D图像; c)投影血管结构,从而基于3D + t图像数据生成多个掩模图像; d)使用所述多个掩模图像之一登记所述至少一个2D图像,其中所述注册包括找到所述掩模图像与所述至少一个2D图像之间的相似性因子的最大值; e)根据所述注册,基于所述3D + t图像数据生成所述至少一个2D图像和所述血管结构的投影的组合; 以及f)将组合显示为引导血管树投影。 因此,由于路线图基于三维数据,所以提供了形成路面图的形式的改进的心脏路线图。
    • 33. 发明授权
    • Mixture of diesters of dianhydrohexitol derivatives with carboxylic acids of the empirical formula C8H17COOH, process for preparing these diesters, and use of these mixtures
    • 二脱水己糖醇衍生物的二酯与经验式C8H17COOH的羧酸的混合物,制备这些二酯的方法以及这些混合物的使用
    • US08258325B2
    • 2012-09-04
    • US12523906
    • 2007-12-21
    • Michael GrassNorbert ScholzAlfred KaizikWilfried BueschkenHans-Gerd Lueken
    • Michael GrassNorbert ScholzAlfred KaizikWilfried BueschkenHans-Gerd Lueken
    • C07D307/93C07D493/00C08G73/06
    • C07D493/04C08K5/1535C08L27/06
    • The present invention relates to a mixture comprising diesters of the formula (I) where R1 to R8═H or alkyl group having from 1 to 6 carbon atoms, where the R1 to R8 radicals may be the same or different, which is characterized in that at least two different diesters I are present in the mixture, said diesters differing in the structure of at least one of the carboxylic acid radicals C8H17COO present, to a process for preparing diesters of an isosorbide derivative of the formula I, in which a hexahydric alcohol and/or a monoanhydro or dianhydro derivative of the alcohol is esterified with a mixture of at least two different carboxylic acids of the empirical formula C8H17COOH, and to the use of these mixtures in paints, inks or coatings, in plastisols, adhesives or adhesive components, in sealants, as plasticizers in polymers or polymer components, as solvents, as lubricant oil components and as assistants in metal processing, and also PVC compositions or plastisols comprising PVC and from 5 to 250 parts by mass of the mixture per 100 parts by mass of PVC.
    • 本发明涉及包含式(I)的二酯的混合物,其中R 1至R 8 = H或具有1至6个碳原子的烷基,其中R 1至R 8基团可以相同或不同,其特征在于 混合物中存在至少两种不同的二酯I,所述二酯在存在的羧酸基团C 8 H 17 COO中的至少一种的结构上不同,制备式I的异山梨醇衍生物的二酯的制备方法,其中六元醇 和/或醇的单酐或二氢衍生物与经验式C 8 H 17 COOH的至少两种不同羧酸的混合物酯化,并且在涂料,油墨或涂料中,在增塑溶胶,粘合剂或粘合剂组分中使用这些混合物 在密封剂中,作为聚合物或聚合物组分中的增塑剂,作为溶剂,作为润滑油组分和作为金属加工助剂,以及PVC组合物或增塑溶胶,其包含PVC和 相对于100质量份的PVC,为5〜250质量份的混合物。
    • 38. 发明申请
    • SYSTEM FOR DETERMINING THE ORIENTATION OF A CATHETER
    • 用于确定导管的方向的系统
    • US20110295111A1
    • 2011-12-01
    • US13148092
    • 2010-02-04
    • Eberhard Sebastian HansisMichael Grass
    • Eberhard Sebastian HansisMichael Grass
    • A61B5/05
    • A61B19/54A61B90/39A61B2034/102A61B2090/376A61F2002/30619A61F2250/0097A61F2250/0098A61M25/0108
    • The present invention relates to a system for determining the orientation of a catheter (2). The system comprises a catheter (2), an asymmetric marker (11) attached to the catheter (2), and an imaging unit (25) for generating a projection image of the asymmetric marker (11), wherein the imaging unit (25) comprises a radiation source for generating radiation for projecting the asymmetric marker (11) in a projection plane and a detection unit for generating the projection image of the asymmetric marker (11) projected in the projection plane. The system comprises further an orientation determination unit for determining the orientation of the asymmetric marker (11) from the projection image of the asymmetric marker (11) and for determining the orientation of the catheter (2) from the determined orientation of the asymmetric marker (11). The asymmetric marker (11) is adapted such that the orientation of the asymmetric marker (11) is determinable from the projection image of the asymmetric marker (11) alone.
    • 本发明涉及一种用于确定导管(2)的取向的系统。 该系统包括导管(2),附接到导管(2)的不对称标记(11)和用于产生不对称标记(11)的投影图像的成像单元(25),其中成像单元(25) 包括用于产生用于在投影平面中投影非对称标记(11)的辐射的辐射源和用于产生投射在投影平面中的不对称标记(11)的投影图像的检测单元。 该系统还包括一个取向确定单元,用于从不对称标记物(11)的投影图像中确定不对称标记物(11)的取向,并确定导管(2)从不对称标记物的确定取向 11)。 不对称标记(11)适于使得非对称标记(11)的取向可以从单独的不对称标记(11)的投影图像确定。
    • 40. 发明申请
    • METHOD AND APPARATUS FOR RECONSTRUCTING AN IMAGE
    • 用于重构图像的方法和装置
    • US20100201786A1
    • 2010-08-12
    • US12300185
    • 2007-05-03
    • Dirk SchaeferMichael Grass
    • Dirk SchaeferMichael Grass
    • H04N13/02G06K9/00
    • G06T7/30G06T2207/30101
    • A reconstruction method for an image of an object under examination is provided, wherein the method comprises, receiving a first projection data set representing three-dimensional information about said object under examination and reconstructing at least one three-dimensional image out of the first projection data set. Further, a second projection data set representing two-dimensional information about the object under examination is received, wherein the second data set was recorded under a first direction and wherein a two-dimensional image out of the second projection data set is generated. Furthermore, a volume rendered projection is reconstructed out of the at least one three-dimensional image using the first direction as the reconstruction direction of the volume rendered projection and the two-dimensional image and the volume rendered projection are overlaid.
    • 提供了一种用于检查对象的图像的重建方法,其中所述方法包括:接收表示关于被检查对象的三维信息的第一投影数据集,并且从所述第一投影数据中重构至少一个三维图像 组。 此外,接收表示关于检查对象的二维信息的第二投影数据集,其中在第一方向记录第二数据集,并且其中生成第二投影数据集中的二维图像。 此外,使用第一方向从所述至少一个三维图像中重建体绘制投影作为体绘制投影的重建方向,并且叠加二维图像和体积渲染投影。