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31. 发明授权

US08753859B2 Amylase polypeptides 有权
标题翻译：淀粉酶多肽
公开(公告)号：US08753859B2
公开(公告)日：2014-06-17
申请号：US13287492
申请日：2011-11-02
申请人： Karsten Matthias Kragh , Anja Hemmingsen Kellet-Smith , René Mikkelsen , Rie Mejldal , Rikke L. Bundgaard Jenner
发明人： Karsten Matthias Kragh , Anja Hemmingsen Kellet-Smith , René Mikkelsen , Rie Mejldal , Rikke L. Bundgaard Jenner
IPC分类号： C12N9/28 , C12N9/26 , C12Q1/40 , C12P19/14 , A23C17/00 , A23L1/31 , C07H21/04
CPC分类号： C12P19/14 , C12N9/2417
摘要： This invention relates to polypeptides, more specifically amylase polypeptides and nucleic acids encoding these, and their uses e.g. as non-maltogenic exoamylases in producing food or feed products.
摘要翻译：本发明涉及多肽，更具体地涉及淀粉酶多肽和编码这些多肽的核酸及其用途。作为生产食品或饲料产品的非麦芽糖外消旋酶。

32. 发明申请

US20120315373A1 METHODS FOR PRODUCING AMINO-SUBSTITUTED GLYCOLIPID COMPOUNDS 有权
标题翻译：制备氨基取代的甘氨酸化合物的方法
公开(公告)号：US20120315373A1
公开(公告)日：2012-12-13
申请号：US13574420
申请日：2011-01-20
申请人： Flemming Vang Sparsø , Karsten Matthias Kragh , Lars Wiebe , Rene Mikkelsen , Anne Katherine Kjærsgaard Laursen
发明人： Flemming Vang Sparsø , Karsten Matthias Kragh , Lars Wiebe , Rene Mikkelsen , Anne Katherine Kjærsgaard Laursen
IPC分类号： C07H1/00 , A23L1/035 , C11D3/386 , C07H15/06
CPC分类号： C07H5/06 , A23K20/105 , A23K20/189 , A23L29/03 , A23L29/10 , A23L33/10 , A23L33/17 , A23L33/21 , A61K8/60 , A61K2800/524 , A61Q19/00 , C07H15/06 , C11D1/42 , C11D1/525 , C11D1/662 , C11D3/227 , C11D3/48 , C11D7/329
摘要： A method of preparing a compound of formula (I): wherein: a first group selected from R1, R2 and R3 is an amino- or N-acylamino monosaccharide moiety, the acyl group having 1 to 6 carbon atoms, or an oligosaccharide chain comprising 2 to 4 monosaccharide moieties, at least one of which is an amino- or N-acylamino monosaccharide moiety; a second group selected from R1, R2 and R3 is a saturated or unsaturated acyi group having 3 to 40 carbon atoms; and a third group selected from R1, R2 and R3 is hydrogen, the method comprising contacting a monoacylglycerol, the acyl moiety thereof being a saturated or unsaturated acyl group having 3 to 40 carbon atoms, or an activated derivative thereof, with a source of amino- or N-acylamino monosaccharide moiety, or an activated derivative thereof, and, if required, a source of unsubstituted monosaccharide moiety, or an activated derivative thereof, optionally in the presence of a suitable catalyst or activating agent, is described. Novel compounds, as well as In situ methods for producing the compounds, and their use as emulsifiers, surfactants and antimicrobial agents, particularly in foodstuffs and detergent compositions, are also described.
摘要翻译：一种制备式（I）化合物的方法：其中：选自R 1，R 2和R 3的第一基团是氨基或N-酰基氨基单糖部分，具有1至6个碳原子的酰基或包含 2至4个单糖部分，其中至少一个是氨基或N-酰基氨基单糖部分; 选自R1，R2和R3的第二个基团是具有3-40个碳原子的饱和或不饱和的亚氨基; 并且选自R 1，R 2和R 3的第三基团是氢，所述方法包括使具有3-40个碳原子的饱和或不饱和酰基的酰基部分或其活化衍生物与单酰基甘油与氨基来源 - 或N-酰基氨基单糖部分或其活化衍生物，并且如果需要，可任选在合适的催化剂或活化剂存在下，描述未取代的单糖部分源或其活化衍生物。还描述了新颖的化合物，以及用于生产化合物的原位方法，以及它们在乳化剂，表面活性剂和抗微生物剂中的用途，特别是在食品和洗涤剂组合物中的用途。

33. 发明授权

US08178090B2 Recombinant hexose oxidase 有权
标题翻译：重组己糖氧化酶
公开(公告)号：US08178090B2
公开(公告)日：2012-05-15
申请号：US12396954
申请日：2009-03-03
申请人： Peter Stougaard , Ole Cai Hansen , Charlotte Horsmans Poulsen , Karsten Matthias Kragh
发明人： Peter Stougaard , Ole Cai Hansen , Charlotte Horsmans Poulsen , Karsten Matthias Kragh
IPC分类号： A61K38/44 , A61K8/00 , A61K8/66 , C12N9/04 , A23K1/165 , A21D8/04 , C12N15/53 , C12N15/70 , C12N15/80
CPC分类号： C12N9/0006 , A01N63/00
摘要： Use of a preparation as an antimicrobial agent or as an anti-oxidant; wherein said preparation comprises a polypeptide having hexose oxidase activity, the polypeptide being in a substantially pure form, and said polypeptide comprises at least one amino acid sequence selected from the group consisting of (i)(SEQ ID NO: 1) Tyr-Glu-Pro-Tyr-Gly-Gly-Val-Pro (ii)(SEQ ID NO: 2) Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly- Tyr-Asp-X-X-X-Gly-Tyr-X-Val-Ser-Ser- (iii)(SEQ ID NO: 3) Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser- Asn-Leu-X-Phe- (iv)(SEQ ID NO: 4) Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His- Thr (v)(SEQ ID NO: 5) Tyr-Tyr-Phe-Lys (vi)(SEQ ID NO: 6) Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly- Thr-X-Asp (vii)(SEQ ID NO: 7) Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp (viii)(SEQ ID NO: 8) X-Ile-Arg-Asp-Phe-Tyr-Glu-Glu-Met where X represents an amino acid selected from the group consisting of Ala, Arg, Asn, Asp, Asx, Cys, Gln, Glu, Glx, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr and Val.
摘要翻译：使用制剂作为抗微生物剂或作为抗氧化剂; 其中所述制剂包含具有己糖氧化酶活性的多肽，所述多肽为基本上纯的形式，所述多肽包含至少一个选自下组的氨基酸序列：（i）（SEQ ID NO：1）Tyr-Glu- Pro-Tyr-Gly-Gly-Val-Pro（ii）（SEQ ID NO：2）Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly-Tyr-Asp-XXX -Gly-Tyr-X-Val-Ser-Ser-（iii）（SEQ ID NO：3）Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser-Asn-Leu -X-Phe-（iv）（SEQ ID NO：4）Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His-Thr（v）（SEQ ID NO： 5）Tyr-Tyr-Phe-Lys（vi）（SEQ ID NO：6）Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly-Thr-X-Asp ）（SEQ ID NO：7）Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp（viii）（SEQ ID NO：8）X-Ile-Arg-Asp-Phe-Tyr -Glu-Glu-Met，其中X表示选自Ala，Arg，Asn，Asp，Asx，Cys，Gln，Glu，Glx，Gly，His，Ile，Leu，Lys，Met，Phe， Pro，Ser，Thr， Trp，Tyr和Val。

34. 发明授权

US07858352B2 Polypeptide 有权
标题翻译：多肽
公开(公告)号：US07858352B2
公开(公告)日：2010-12-28
申请号：US11635511
申请日：2006-12-08
申请人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
发明人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
IPC分类号： C12N9/28 , C12N15/00 , C12N9/88
CPC分类号： A21D8/042 , A23K20/189 , A23L29/35 , C12N9/2417 , C12Y302/0106
摘要： We disclose a PS4 variant polypeptide derivable from a parent polypeptide, the parent polypeptide having non-maltogenic exoamylase activity, which PS4 variant polypeptide comprises one or more of the following substitutions: G69P, A141P, G223A, A268P, G313P, S399P and G400P, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1. Such PS4 variant polypeptides may be used as exo-amylases, particularly as non-maltogenic exoamylases. Combinations of such PS4 variant polypeptides together with Novamyl are disclosed.
摘要翻译：我们公开了可从母体多肽衍生的PS4变体多肽，该亲本多肽具有非产麦芽糖外切酶活性，该PS4变体多肽包含一个或多个以下取代：G69P，A141P，G223A，A268P，G313P，S399P和G400P，具有提及如SEQ ID NO：1所示的假单胞菌糖酵母外切酶序列的位置编号。这样的PS4变体多肽可以用作外切淀粉酶，特别是作为非发酵的外消旋酶。公开了这些PS4变体多肽与Novamyl的组合。

35. 发明授权

US07166453B2 Polypeptide 有权
标题翻译：多肽
公开(公告)号：US07166453B2
公开(公告)日：2007-01-23
申请号：US10864874
申请日：2004-06-10
申请人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
发明人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
IPC分类号： C12N9/28 , C12N15/00 , C12N9/88 , C07H21/04
CPC分类号： A21D8/042 , A23K20/189 , A23L29/35 , C12N9/2417 , C12Y302/0106
摘要： We disclose a PS4 variant polypeptide derivable from a parent polypeptide, the parent polypeptide having non-maltogenic exoamylase activity, which PS4 variant polypeptide comprises one or more of the following substitutions: G69P, A141P, G223A, A268P, G313P, S399P and G400P, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1. Such PS4 variant polypeptides may be used as exo-amylases, particularly as non-maltogenic exoamylases. Combinations of such PS4 variant polypeptides together with Novamyl are disclosed.
摘要翻译：我们公开了可从母体多肽衍生的PS4变体多肽，该亲本多肽具有非产麦芽糖外切酶活性，该PS4变体多肽包含一个或多个以下取代：G69P，A141P，G223A，A268P，G313P，S399P和G400P，具有提及如SEQ ID NO：1所示的假单胞菌糖酵母外切酶序列的位置编号。这样的PS4变体多肽可以用作外切淀粉酶，特别是作为非发酵的外消旋酶。公开了这些PS4变体多肽与Novamyl的组合。

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