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    • 33. 发明授权
    • Passive ventricular support devices and methods of using them
    • 被动心室支持装置及其使用方法
    • US06695769B2
    • 2004-02-24
    • US09963921
    • 2001-09-25
    • Ronald G. FrenchSunmi K. ChewHanson S. Gifford, IIIBernard H. Andreas
    • Ronald G. FrenchSunmi K. ChewHanson S. Gifford, IIIBernard H. Andreas
    • A61M3100
    • A61F2/2481A61F2002/2484
    • This is a surgical device and a method of using it. In particular, the device is one for supporting or constraining at least some part of the epicardial surface of the heart during a portion of the heartbeat, in particular during diastoly. This device may be used to assist in the treatment of congestive heart failure. The device, generically, is an enclosure having an interior and an exterior. The interior surface is preferably made in such a way that it tends not to or does not form adhesions with or accept ingrowth with the myocardial tissue of the epicardium. The device preferably has at least on rib-like structural member. The rib component may extend from end-to end or preferably extends helically around the heart, preferably with at least one revolution. The device may be configured to be self-adherent, i.e., preferably adherent only to itself, and to form a unitary support in the pericardial space after installation. This device helps to prevent further declination of the heart during congestive heart failure. The device is preferably introduced into the pericardial space and onto the surface of the epicardium using transcutaneous or minimally invasive techniques.
    • 这是一种手术装置及其使用方法。 特别地,该装置是用于在心跳的一部分期间特别是在舒张期期间用于支撑或约束心脏的心外膜表面的至少一部分的装置。 该装置可用于协助治疗充血性心力衰竭。 该装置通常是具有内部和外部的外壳。 内表面优选地制成其倾向于不与或不与心外膜的心肌组织形成粘连或与内膜的心肌组织接触向内生长。 该装置优选地至少具有肋状结构构件。 肋组件可以从端到端延伸或者优选地围绕心脏螺旋地延伸,优选地以至少一圈的方式延伸。 该装置可以被配置为自粘附的,即优选地仅附着于其自身,并且在安装之后在心包空间中形成整体支撑。 该装置有助于防止在充血性心力衰竭期间心脏的进一步下降。 该装置优选使用经皮或微创技术引入心包空间和外膜表面。
    • 34. 发明授权
    • Ventricular infarct assist device and methods for using it
    • 心室梗死辅助装置及其使用方法
    • US06685620B2
    • 2004-02-03
    • US09964070
    • 2001-09-25
    • Hanson S. Gifford, IIIBernard H. Andreas
    • Hanson S. Gifford, IIIBernard H. Andreas
    • A61F100
    • A61F2/2481A61B17/00234A61B17/0401A61B2017/0419
    • This relates to surgical devices and methods of using them. In particular, the devices are used to support and to reform myocardial tissue in the region of and across an infarct. The devices provide tension across the infarct in varying degrees by attachment of the device to the myocardium at sites adjacent the infarct. A support-providing component across the infarct, between the heart attachment sites, provides support to the myocardial wall and support across the infarct. Optionally, but preferably, the support-providing component includes a time-delay element that variously may allow the device to be introduced onto the myocardial surface and to change the support of the support element over time.
    • 这涉及手术装置和使用它们的方法。 特别地,这些装置用于支持和改变梗死区域内和跨越梗死区域的心肌组织。 这些装置通过在与梗塞相邻的位置处将装置附接到心肌而在不同程度上提供跨梗死的张力。 在心脏附着位点之间的梗死区域的支持提供组件提供对心肌壁的支持并跨越梗塞的支持。 可选地,但是优选地,支撑提供部件包括时间延迟元件,其可以不同地允许将装置引入心肌表面并随时间改变支撑元件的支撑。
    • 36. 发明授权
    • Device and method for suturing of internal puncture sites
    • 缝合内部穿刺部位的装置及方法
    • US06206893B1
    • 2001-03-27
    • US09057108
    • 1998-04-08
    • Enrique J. KleinBernard H. Andreas
    • Enrique J. KleinBernard H. Andreas
    • A61B1704
    • A61B17/0482A61B17/0057A61B17/0469A61B17/06066A61B2017/00637A61B2017/00641A61B2017/00663A61B2017/0472A61B2017/22038A61B2017/2927A61F2002/30093A61F2210/0019
    • A suture applying device comprises a shaft having a nose piece attached at its distal end. The shaft and the nose piece are separated by a transition region, and a needle entry lumen in the shaft permits a flexible needle to be introduced in the distal direction. The needle is able to cross the transition region and penetrate tissue held therein and enter into a return lumen in the nose piece. The return lumen is U-shaped and acts to bend the flexible needle as it is advanced. In this way, the needle passes from the nose piece through the transition region in a proximal direction, and is able to pass through tissue within the transition region generally on the opposite side of a tissue puncture from the first suture passage. The needle then exits from the device, permitting the suture attached to the needle to be drawn fully through the device. The suture may then be tied in order to close and seal the tissue penetration.
    • 缝线施加装置包括具有在其远端附接的鼻片的轴。 轴和鼻片由过渡区域分开,轴中的针入口允许柔性针沿远端方向被引入。 针能够穿过过渡区域并穿透保持在其中的组织并进入鼻片中的返回内腔。 返回内腔是U形的,并且用于使柔性针在其前进时弯曲。 以这种方式,针从鼻片穿过过渡区域沿近端方向穿过,并且能够穿过过渡区域内的组织,通常在组织穿刺的相对侧上从第一缝合线通道穿过。 然后针从装置中离开,允许附着在针上的缝合线被完全拉出穿过装置。 然后可以将缝合线捆扎以封闭并密封组织穿透。
    • 37. 发明授权
    • Atherectomy catheter
    • 动脉粥样硬化切除术导管
    • US5669920A
    • 1997-09-23
    • US618943
    • 1996-03-20
    • Daniel J. ConleyMark E. DeemKent D. DellBernard H. Andreas
    • Daniel J. ConleyMark E. DeemKent D. DellBernard H. Andreas
    • A61B17/22A61M25/00
    • A61B17/320783A61M25/0012A61B2017/22069A61M25/0009A61M25/005A61M25/0053
    • An improved atherectomy catheter and methods of making and using a catheter are disclosed. In one embodiment, the catheter comprises a housing shaft having a torsionally-reinforced outer layer concentrically disposed over a polymeric inner layer, with an inflation tube disposed concentrically over the housing shaft to define an annular inflation lumen. A housing is attached to the distal end of the housing shaft, and may contain interventional means such as a cutting blade. The balloon for urging the housing against a vessel wall, such as a balloon, is attached to the housing opposite the interventional means and is in communication with the inflation lumen. A drive shaft may be rotatably disposed through a longitudinal lumen in the housing shaft, the drive shaft being coupled at its distal end to the interventional balloon. The method of the invention facilitates construction of a catheter shaft through the steps of forming a flexible tubular polymeric outer layer with a first melting point over a tubular polymeric inner layer with a second melting point, the first melting point being lower than the second melting point; heating the outer layer to at least the first melting point and less than the second melting point, and impregnating a wire braid into the outer layer up to the inner layer. In a preferred embodiment, the inner layer is a fluorocarbon polymer, and the outer layer is a thermoplastic elastomer which is stable near body temperatures, impregnated with one or more layers of a stainless steel wire braid.
    • 公开了改进的粥样斑块切除术导管和制造和使用导管的方法。 在一个实施例中,导管包括壳体轴,其具有同心地设置在聚合物内层上方的扭转增强的外层,同心放置在壳体轴上以限定环形膨胀腔。 壳体附接到壳体轴的远端,并且可以包含诸如切割刀片的介入装置。 用于将壳体推靠在容器壁(例如气球)上的气囊被附接到与介入装置相对的壳体并与膨胀腔连通。 驱动轴可以可旋转地设置穿过壳体轴中的纵向内腔,驱动轴在其远端处连接到介入气囊。 本发明的方法有助于通过以下步骤形成导管轴的构造:在具有第二熔点的管状聚合物内层上形成具有第一熔点的柔性管状聚合物外层,第一熔点低于第二熔点 ; 将外层加热到至少第一熔点并小于第二熔点,并将丝编织物浸入外层直到内层。 在优选的实施方案中,内层是碳氟聚合物,外层是热塑性弹性体,其在体温附近是稳定的,浸渍有一层或多层不锈钢丝编织物。