专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US5529787A Hydromorphone therapy 失效
公开(公告)号：US5529787A
公开(公告)日：1996-06-25
申请号：US271593
申请日：1994-07-07
申请人： Sonya Merrill , Atul D. Ayer , Navjot Chadha , Anthony L. Kuczynski
发明人： Sonya Merrill , Atul D. Ayer , Navjot Chadha , Anthony L. Kuczynski
IPC分类号： A61K9/00 , A61K9/20 , A61K31/485 , A61P23/00 , A01N43/08 , A61K9/22
CPC分类号： A61K9/2027 , A61K31/485 , A61K9/0004 , A61K9/2031 , A61K9/2054
摘要： A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.

32. 发明授权

US5460826A Morphine therapy 失效
标题翻译：吗啡治疗
公开(公告)号：US5460826A
公开(公告)日：1995-10-24
申请号：US266075
申请日：1994-06-27
申请人： Sonya Merrill , Atul D. Ayer , Paul Hwang , Anthony L. Kuczynski
发明人： Sonya Merrill , Atul D. Ayer , Paul Hwang , Anthony L. Kuczynski
IPC分类号： A61K9/00 , A61K9/20 , A61K9/36 , A61K31/485 , A61K47/30 , A61P25/04 , A61K9/22 , A61K9/24
CPC分类号： A61K9/2031 , A61K31/485 , A61K9/0004 , A61K9/2027
摘要： A bilayer comprising a morphine layer of morphine, poly(alkylene oxide) and poly(vinylpyrrolidone); and an expandable contacting layer of coated granules of a higher molecular weight poly(alkylene oxide) and a hydroxyalkylcellulose, which bilayer is disclosed for morphine therapy. A method is disclosed for using the bilayer composition.
摘要翻译：包含吗啡吗啉，聚（环氧烷）和聚（乙烯基吡咯烷酮）的双层; 以及较高分子量聚（环氧烷）和羟烷基纤维素的包衣颗粒的可膨胀接触层，其中公开了用于吗啡治疗的双层。公开了使用双层组合物的方法。

33. 发明授权

US5246711A Dosage form for treating dysthymia 失效
标题翻译：用于治疗心境恶劣的剂型
公开(公告)号：US5246711A
公开(公告)日：1993-09-21
申请号：US943618
申请日：1992-09-10
申请人： Atul D. Ayer , Dana Ridzon
发明人： Atul D. Ayer , Dana Ridzon
IPC分类号： A61K9/00 , A61K31/495 , A61K31/496 , A61K31/505
CPC分类号： A61K31/505 , A61K31/495 , A61K31/496 , A61K9/0004
摘要： A dosage form is provided for administering a drug of the formula ##STR1## to a patient to produce an anxiolytic benefit in the patient.
摘要翻译：提供给患者施用式“IMAGE”的药物以在患者中产生抗焦虑益处的剂型。

34. 发明授权

US5192550A Dosage form for treating central nervous system disorders 失效
标题翻译：用于治疗中枢神经系统疾病的剂型
公开(公告)号：US5192550A
公开(公告)日：1993-03-09
申请号：US846097
申请日：1992-03-05
申请人： David E. Edgren , Howard A. Carpenter , Gurdish K. Bhatti , Atul D. Ayer
发明人： David E. Edgren , Howard A. Carpenter , Gurdish K. Bhatti , Atul D. Ayer
IPC分类号： A61K9/00
CPC分类号： A61K9/0004
摘要： A dosage form is disclosed comprising an anti-Parkinson's disease drug for administering to a patient in need of anti-Parkinson's disease therapy.
摘要翻译：公开了一种剂型，其包含用于给予需要抗帕金森病治疗的患者的抗帕金森病药物。

35. 发明授权

US4946687A Dosage form for treating cardiovascular diseases 失效
标题翻译：用于治疗心血管疾病的剂型
公开(公告)号：US4946687A
公开(公告)日：1990-08-07
申请号：US267894
申请日：1988-11-07
申请人： Atul D. Ayer , David R. Swanson , Anthony L. Kuczynski
发明人： Atul D. Ayer , David R. Swanson , Anthony L. Kuczynski
IPC分类号： A61K9/00 , A61K31/44
CPC分类号： A61K31/44 , A61K9/0004
摘要： An osmotic device is disclosed comprising a first composition, and a second composition with the beneficial drug isradipine in the first composition.
摘要翻译：公开了一种渗透装置，其包含第一组合物，第二组合物在第一组合物中具有有益药物阿拉度铂。

36. 发明授权

US4814181A Dosage form comprising fast agent delivery followed by slow agent delivery 失效
标题翻译：剂型包括快速药物递送，然后慢剂递送
公开(公告)号：US4814181A
公开(公告)日：1989-03-21
申请号：US92857
申请日：1987-09-03
申请人： Maureen L. Jordan , Atul D. Ayer , Paul R. Magruder , David E. Edgren
发明人： Maureen L. Jordan , Atul D. Ayer , Paul R. Magruder , David E. Edgren
IPC分类号： A61K9/00 , A61K9/22 , A61K9/52 , A61K9/24
CPC分类号： A61K9/0004
摘要： A dosage form is disclosed comprising a wall that surrounds a compartment with an exit means in the wall. The compartment comprises a first or fast releasing lamina and a second or short releasing lamina that are delivered through the exit means over two different periods of time.
摘要翻译：公开了一种剂型，其包括围绕隔室的壁，壁上具有出口装置。隔室包括第一或快速释放层和经由出口装置在两个不同时间段内输送的第二或短释放层。

37. 发明授权

US4693886A Osmotic device with inert core 失效
标题翻译：具有惰性芯的渗透装置
公开(公告)号：US4693886A
公开(公告)日：1987-09-15
申请号：US725840
申请日：1985-04-22
申请人： Atul D. Ayer
发明人： Atul D. Ayer
IPC分类号： A61K9/00 , A61K9/22 , A61K9/24 , A61K9/44
CPC分类号： A61K9/0004
摘要： An osmotic dispensing device is disclosed for delivering a medicine to a biological environment of use. The device comprises a semipermeable wall surrounding a compartment with an osmotic passageway in the semipermeable wall connecting the outside of the device with the compartment. The compartment house a medicine releasably held on a carrier member.
摘要翻译：公开了用于将药物递送到生物生物学环境的渗透分配装置。该装置包括围绕隔室的半透壁，该隔室具有连接设备外部与隔室的半透壁中的渗透通道。隔室装有可释放地保持在承载构件上的药物。

38. 发明授权

US4014334A Laminated osmotic system for dispensing beneficial agent 失效
标题翻译：用于分配有益剂的层压渗透系统
公开(公告)号：US4014334A
公开(公告)日：1977-03-29
申请号：US654194
申请日：1976-02-02
申请人： Felix Theeuwes , Atul D. Ayer
发明人： Felix Theeuwes , Atul D. Ayer
IPC分类号： A61F9/00 , A61K9/00 , A61M31/00
CPC分类号： A61K9/0004 , A61F9/0017
摘要： An osmotic system for delivering a beneficial agent to an environment of use is disclosed. The system comprises a laminate surrounding a compartment and has a passageway through the laminate for releasing agent from the compartment. The laminate comprises at least two laminae; one consisting of a semipermeable, polymeric material that is permeable to the passage of an external fluid and maintains its physical and chemical integrity in the environment of use, and one consisting of a semipermeable polymeric material that is permeable to the passage of the fluid, substantially impermeable to the passage of agent and maintains its physical and chemical integrity in the presence of agent. The compartment comprises an active agent that is either soluble in the external fluid and exhibits an osmotic pressure gradient across the laminate against the fluid, or the agent has limited solubility in the fluid and it is mixed with an osmotically effective compound that is soluble in the fluid and exhibits an osmotic pressure gradient across the laminate against the fluid. In operation, agent is released from the system by fluid being imbibed through the laminate into the compartment at a rate controlled by the permeability of the laminate and the osmotic pressure gradient across the laminate producing a solution containing agent, or a solution of compound containing agent which solution in either operation is released through the passageway at a controlled and continuous rate over a prolonged period of time.
摘要翻译：公开了一种用于将有益剂递送到使用环境的渗透系统。该系统包括围绕隔室的层压板，并具有通过层压板的通道，用于将隔离物释放。层压体包括至少两层; 一种由可渗透外部流体通道并在使用环境中保持其物理和化学完整性的半透性聚合材料组成，并且由可渗透流体的半透性聚合物材料组成，基本上通过试剂不渗透，并在试剂存在下保持其物理和化学完整性。隔室包含可溶于外部流体的活性剂，并且表现出横跨该层压体的流体的渗透压梯度，或者该试剂在流体中具有有限的溶解度，并且与渗透性有效的化合物混合，该化合物可溶于并且表现出跨过层压体抵抗流体的渗透压梯度。在操作中，通过流体通过层压体被吸收到隔室中的剂量从层压体的渗透性控制的速率和穿过层压体的渗透压梯度产生包含溶液的试剂或含化合物的溶液任何操作中的解决方案在长时间内以受控和连续的速率通过通道释放。

39. 发明申请

US20100028389A1 HYDROMORPHONE THERAPY 审中-公开
标题翻译：水疗治疗
公开(公告)号：US20100028389A1
公开(公告)日：2010-02-04
申请号：US12572106
申请日：2009-10-01
申请人： Sonya Merrill , Atul D. Ayer , Navjot Chadha , Anthony L. Kuczynski
发明人： Sonya Merrill , Atul D. Ayer , Navjot Chadha , Anthony L. Kuczynski
IPC分类号： A61K9/00 , A61K31/4355
CPC分类号： A61K9/0004 , A61K9/2027 , A61K9/2031 , A61K9/2054 , A61K31/485
摘要： A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.
摘要翻译：公开了用于治疗疼痛的氢吗啡酮组合物，氢吗啡酮剂型和用于给予氢吗啡酮的方法。

40. 发明授权

US5869097A Method of therapy comprising an osmotic caplet 失效
标题翻译：包括渗透囊片的治疗方法
公开(公告)号：US5869097A
公开(公告)日：1999-02-09
申请号：US970519
申请日：1992-11-02
申请人： Patrick S.-L. Wong , Felix Theeuwes , George V. Guittard , Atul D. Ayer
发明人： Patrick S.-L. Wong , Felix Theeuwes , George V. Guittard , Atul D. Ayer
IPC分类号： A61K9/24 , A61K9/26 , A61K9/52
CPC分类号： A61K9/0004 , A61K9/1635 , A61K9/4808 , A61K9/4816 , A61K9/4891
摘要： An osmotic caplet is disclosed comprising an osmotic caplet exit for delivering a preselected dose of drug to a patient in need of therapy.
摘要翻译：公开了渗透性囊片，其包括用于将预选剂量的药物递送至需要治疗的患者的渗透性囊片出口。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式