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31. 发明申请

US20190328965A1 DRUG DELIVERY DEVICE WITH PLACEMENT DETECTION 审中-公开
公开(公告)号：US20190328965A1
公开(公告)日：2019-10-31
申请号：US16312268
申请日：2017-07-20
申请人： AMGEN INC.
发明人： Sheldon Moberg
IPC分类号： A61M5/172 , A61M5/20
摘要： A drug delivery device includes a housing, a primary container, a cannula, a delivery mechanism, an electrode, and a controller. The housing defines an interior cavity and a distal surface for contacting a patient during use of the drug delivery device. The primary container is disposed in the interior cavity of the housing and adapted to contain a drug. At least a portion of the cannula is electrically conductive, with the cannula being disposed in fluid communication with the primary container. The drug delivery device is adapted to occupy a storage state where a terminal end of the cannula is inside the housing and a delivery state where the terminal end of the cannula extends out through an opening in the distal surface of the housing. The delivery mechanism is disposed in the housing for selectively forcing the drug out of the primary container and through the cannula for delivery to a patient when the cannula occupies the delivery state. The electrode is disposed on the distal surface of the housing. Finally, the controller is carried by the housing and electrically connected to the delivery cannula and the electrode such that upon application of the distal surface of the housing onto a patient's skin and insertion of the delivery cannula into the patient the controller recognizes a closed electrical circuit including the cannula and the electrode.

32. 发明申请

US20190298927A1 METHOD OF ASSEMBLING AND FILLING A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20190298927A1
公开(公告)日：2019-10-03
申请号：US16401471
申请日：2019-05-02
申请人： AMGEN INC.
发明人： Francisca Tan-Malecki , Ronald Forster , Scott M. Nunn , Mark D. Holt , Son C. Tran , Sheldon Moberg
IPC分类号： A61M5/31 , B65B55/10 , A61M5/162 , A61M5/24 , A61M5/172 , A61M5/145 , B65B55/08 , B65B7/28 , B65B3/00 , A61M5/158 , A61M5/148
摘要： An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

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