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31. 发明申请

US20160199647A1 SYSTEMS AND METHODS FOR FACILITATING APICAL ELECTRODE STIMULATION BY AN ELECTRO-ACOUSTIC STIMULATION SYSTEM 有权
标题翻译：通过电声刺激系统促进生物电刺激的系统和方法
公开(公告)号：US20160199647A1
公开(公告)日：2016-07-14
申请号：US15079032
申请日：2016-03-23
申请人： ADVANCED BIONICS AG
发明人： Mark B. Downing , Leonid M. Litvak
IPC分类号： A61N1/36 , H04R25/00 , A61N1/05
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036 , A61N1/37247 , H04R25/02 , H04R25/606 , H04R2225/67
摘要： An exemplary system includes an electro-acoustic stimulation (“EAS”) device, a cochlear implant, an electrode lead comprising a plurality of basal electrodes configured to be disposed within a basal region of a cochlea of a patient and a plurality of apical electrodes configured to be disposed within an apical region of the cochlea; and a loudspeaker communicatively coupled to the EAS device. The EAS device is configured to operate in an EAS mode by 1) disabling the apical electrodes for standard electrical stimulation, 2) detecting, while the apical electrodes are disabled for standard electrical stimulation, audio content presented to the patient and included in an acoustic stimulation frequency range, 3) directing the loudspeaker to apply acoustic stimulation representative of the audio content included in the acoustic stimulation frequency range to the patient, and 4) periodically directing the cochlear implant to apply conditioning stimulation by way of the disabled apical electrodes.
摘要翻译：一种示例性系统包括电声刺激（“EAS”）装置，耳蜗植入物，包括多个基底电极的电极引线，其被配置为设置在患者的耳蜗的基底区域内，并配置有多个顶端电极被布置在耳蜗的顶端区域内; 以及通信地耦合到EAS设备的扬声器。 EAS设备被配置为以EAS模式操作，1）禁用用于标准电刺激的顶端电极，2）当顶端电极被禁用以进行标准电刺激时，检测出呈现给患者的音频内容并包括在声学刺激中频率范围，3）引导扬声器将表示声刺激频率范围内的音频内容的声学刺激应用于患者，以及4）周期性地引导耳蜗植入物，以通过残留的顶端电极施加调节刺激。

32. 发明申请

US20150328457A1 SYSTEMS AND METHODS FOR CONTROLLING A WIDTH OF AN EXCITATION FIELD CREATED BY CURRENT APPLIED BY A COCHLEAR IMPLANT SYSTEM 有权
标题翻译：用于控制由COCHLEAR IMPLANT系统应用的电流产生的激励的宽度的系统和方法
公开(公告)号：US20150328457A1
公开(公告)日：2015-11-19
申请号：US14651628
申请日：2013-11-29
申请人： ADVANCED BIONICS AG
发明人： Leonid M. Litvak , Michael S. Marzalek
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36032 , A61N1/36036 , F04C2270/0421
摘要： An exemplary sound processor (104) 1) identifies a stimulation site within a cochlea of a patient that is to be stimulated in order to represent acoustic content presented to the patient, the stimulation site included within a plurality of stimulation sites associated with a stimulation channel corresponding to a plurality of electrodes, 2) determines a target excitation field width associated with the stimulation channel and 3) dynamically sets, based on the identified stimulation site, an amplitude and a polarity of current to be applied to each electrode included in the plurality of electrodes in order to represent the acoustic content so that an excitation field created by the current has a width that roughly matches the target excitation field width. A system and a corresponding method are also disclosed.
摘要翻译：示例性声音处理器（104）1）识别待刺激的患者的耳蜗内的刺激部位，以便表示呈现给患者的声学内容，所述刺激部位包括在与刺激通道相关联的多个刺激部位内对应于多个电极，2）确定与刺激通道相关联的目标激励场宽度; 3）基于所识别的刺激位置动态地设置要施加到多个电极中包括的每个电极的电流的幅度和极性的电极以便表示声音内容，使得由电流产生的激励场具有与目标激励场宽大致匹配的宽度。还公开了一种系统和相应的方法。

33. 发明申请

US20150328456A1 FOCUSING SYSTEMS AND METHODS FOR USE IN A COCHLEAR IMPLANT SYSTEM 审中-公开
标题翻译：聚焦系统和用于COCHLEAR植入系统的方法
公开(公告)号：US20150328456A1
公开(公告)日：2015-11-19
申请号：US14651625
申请日：2013-11-29
申请人： Advanced Bionics AG
发明人： Leonid M. Litvak , Michael S. Marzalek
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36036 , F04C2270/0421
摘要： An exemplary sound processor (104) may 1) identify a stimulation site within a cochlea of a patient that is to be stimulated in order to represent an audio signal presented to the patient, 2) dynamically designate, based on the identified stimulation site, a first group of one or more electrodes as a group of one or more main electrodes and a second group of one or more electrodes as a group of one or more compensating electrodes and 3) dynamically determine, based on the identified stimulation site, an amount of main current to be applied to each electrode included in the first group of one or more electrodes in order to represent the audio signal and an amount of compensating current to be applied to each electrode included in the second group of one or more electrodes to focus an excitation field created by the main current.
摘要翻译：示例性声音处理器（104）可以1）识别待刺激的患者的耳蜗内的刺激部位，以便表示呈现给患者的音频信号，2）基于所识别的刺激部位动态地指定一个作为一个或多个主电极的组的一个或多个电极的第一组和作为一个或多个补偿电极的组的一个或多个电极的第二组，以及3）基于所识别的刺激部位来动态地确定要施加到包括在第一组一个或多个电极中的每个电极的主电流，以便表示要施加到包括在第二组一个或多个电极中的每个电极的音频信号和补偿电流的量，以聚焦由主电流产生的励磁场。

34. 发明授权

US08914124B2 Tonality-based optimization of sound sensation for a cochlear implant patient 有权
标题翻译：基于音调的耳蜗植入患者声音优化
公开(公告)号：US08914124B2
公开(公告)日：2014-12-16
申请号：US13799575
申请日：2013-03-13
申请人： Advanced Bionics AG
发明人： Leonid M. Litvak , Abhijit Kulkarni
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036 , H04R2225/67
摘要： An exemplary system includes a sound processor configured to 1) divide an audio signal into a plurality of analysis channels and 2) generate one or more tonality indices each representing a tonality of one of the analysis channels, and an implantable cochlear stimulator communicatively coupled to the sound processor and configured to 1) generate one or more stimulation pulses configured to represent the audio signal in accordance with one or more stimulation parameters, and 2) adjust the one or more stimulation parameters based on at least one of the tonality indices.
摘要翻译：一个示例性系统包括：声音处理器，其被配置为：1）将音频信号划分成多个分析通道; 2）产生一个或多个音调指数，每个音调指数表示分析通道之一的音调;以及可植入的耳蜗刺激器，声音处理器，并且被配置为1）根据一个或多个刺激参数产生被配置为表示音频信号的一个或多个刺激脉冲，以及2）基于音调指数中的至少一个调整一个或多个刺激参数。

35. 发明申请

US20140336725A1 METHODS AND SYSTEMS FOR LOWERING A PITCH SENSATION AS PERCEIVED BY A COCHLEAR IMPLANT PATIENT 有权
标题翻译：用于降低由COCHLEAR IMPLAN患者感受到的PITCH感觉的方法和系统
公开(公告)号：US20140336725A1
公开(公告)日：2014-11-13
申请号：US14361251
申请日：2012-11-28
申请人： ADVANCED BIONICS AG
发明人： Waldo Nogueira , Leonid M. Litvak , Aniket Saoji
IPC分类号： A61N1/36 , H04R25/00
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036 , A61N1/37252 , H04R25/50
摘要： An exemplary method of lowering a pitch sensation as perceived by a cochlear implant patient includes 1) identifying a most apical electrode included in a plurality of electrodes disposed within a cochlea of the patient, 2) directing a cochlear implant communicatively coupled to the plurality of electrodes to apply one or more anodecathode biphasic stimulation pulses to the most apical electrode during a stimulation period, and 3) directing the cochlear implant to apply one or more cathode-anode biphasic stimulation pulses to one or more other electrodes included in the plurality of electrodes during the stimulation period. Corresponding methods and systems are also disclosed.
摘要翻译：降低耳蜗植入患者感觉到的俯仰感觉的示例性方法包括：1）识别包括在设置在患者的耳蜗内的多个电极中的最顶端电极，2）引导通信地耦合到多个电极的耳蜗植入物在刺激期间将一个或多个阳极阴极双相刺激脉冲施加到最顶端电极，以及3）引导耳蜗植入物将一个或多个阴极 - 阳极双相刺激脉冲施加到包括在多个电极中的一个或多个其它电极刺激期。还公开了相应的方法和系统。

36. 发明申请

US20130282077A1 Channel-Specific Adjustment of Sound Processing Strategies Based on Electrode Impedance 有权
标题翻译：基于电极阻抗的声音处理策略的通道特定调整
公开(公告)号：US20130282077A1
公开(公告)日：2013-10-24
申请号：US13919544
申请日：2013-06-17
申请人： Advanced Bionics AG
发明人： Aniket Saoji , Leonid M. Litvak
IPC分类号： A61N1/36
CPC分类号： A61N1/36032 , A61N1/36036 , A61N1/36185 , A61N1/37252 , A61N2001/083 , H04R25/505 , H04R25/606 , H04R2460/03
摘要： An exemplary method includes a sound processing unit 1) directing an implantable cochlear stimulator to apply a plurality of stimulation pulses each having a first pulse width by way of a plurality of electrodes during a first stimulation frame, the plurality of electrodes including a first electrode and a set of remaining electrodes, 2) detecting a change in impedance of the first electrode, 3) adjusting, in response to the change in impedance of the first electrode, a pulse width parameter associated with the first electrode to define a second pulse width, and 4) directing the implantable cochlear stimulator to apply a stimulation pulse having the second pulse width by way of the first electrode and a plurality of stimulation pulses having the first pulse width by way of the set of remaining electrodes during a second stimulation frame subsequent to the first stimulation frame.
摘要翻译：一种示例性方法包括声音处理单元1）引导可植入耳蜗刺激器在第一刺激帧期间通过多个电极施加各自具有第一脉冲宽度的多个刺激脉冲，所述多个电极包括第一电极和一组剩余电极，2）检测第一电极的阻抗变化，3）响应于第一电极的阻抗变化调整与第一电极相关联的脉冲宽度参数以限定第二脉冲宽度，以及4）引导所述可植入耳蜗刺激器在第二刺激帧之后通过所述第一电极施加具有所述第二脉冲宽度的刺激脉冲和经由所述剩余电极组的所述第一脉冲宽度的多个刺激脉冲，第一刺激框架。

37. 发明申请

US20130197606A1 Tonality-Based Optimization of Sound Sensation for a Cochlear Implant Patient 有权
标题翻译：基于音调的耳蜗植入患者声音感知优化
公开(公告)号：US20130197606A1
公开(公告)日：2013-08-01
申请号：US13799575
申请日：2013-03-13
申请人： Advanced Bionics AG
发明人： Leonid M. Litvak , Abhijit Kulkarni
IPC分类号： A61N1/36
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036 , H04R2225/67
摘要： An exemplary system includes a sound processor configured to 1) divide an audio signal into a plurality of analysis channels and 2) generate one or more tonality indices each representing a tonality of one of the analysis channels, and an implantable cochlear stimulator communicatively coupled to the sound processor and configured to 1) generate one or more stimulation pulses configured to represent the audio signal in accordance with one or more stimulation parameters, and 2) adjust the one or more stimulation parameters based on at least one of the tonality indices.
摘要翻译：一个示例性系统包括：声音处理器，其被配置为：1）将音频信号划分成多个分析通道; 2）产生一个或多个音调指数，每个音调指数表示分析通道之一的音调;以及可植入的耳蜗刺激器，声音处理器，并且被配置为1）根据一个或多个刺激参数产生被配置为表示音频信号的一个或多个刺激脉冲，以及2）基于音调指数中的至少一个调整一个或多个刺激参数。

38. 发明申请

US20220296898A1 SYSTEMS AND METHODS FOR DETECTING ELECTRODE LEAD PROXIMITY TO COCHLEAR TISSUE 有权
公开(公告)号：US20220296898A1
公开(公告)日：2022-09-22
申请号：US17833572
申请日：2022-06-06
申请人： Advanced Bionics AG
发明人： Kanthaiah Koka , Leonid M. Litvak
IPC分类号： A61N1/36 , A61N1/02 , A61N1/05 , A61N1/08
摘要： An illustrative proximity detection system directs a first electrode of an electrode lead to apply a first pulse and directs a second electrode of the electrode lead to apply a second pulse concurrently with the first pulse so as to form a dipole that generates a field. The first and second electrodes are each configured as stimulating electrodes that apply stimulation to the cochlear tissue when the electrode lead is located at a resting position subsequent to a surgical insertion of the electrode lead into a cochlea of a patient. After the pulses are applied, and based on an energy magnitude of the field that is detected to reflect from cochlear tissue located within the field, the proximity detection system determines a proximity of the electrode lead to the cochlear tissue. Corresponding systems and methods are also disclosed.

39. 发明申请

US20220233861A1 USE OF ONE OR MORE EVOKED RESPONSE SIGNALS TO DETERMINE AN INSERTION STATE OF AN ELECTRODE LEAD DURING AN ELECTRODE LEAD INSERTION PROCEDURE 有权
公开(公告)号：US20220233861A1
公开(公告)日：2022-07-28
申请号：US17620027
申请日：2020-04-30
申请人： Advanced Bionics AG
发明人： Leonid M. Litvak , Kanthaiah Koka
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08 , A61N1/02
摘要： An exemplary diagnostic system is configured to direct an acoustic stimulation generator to an acoustic stimulation generator to apply acoustic stimulation having a plurality of stimulus frequencies to a recipient of a cochlear implant during an insertion procedure in which an electrode lead communicatively coupled to the cochlear implant is inserted into a cochlea of the recipient, direct the cochlear implant to use an electrode disposed on the electrode lead to record a plurality of evoked response signals during the insertion procedure, each evoked response signal included in the plurality of evoked response signals corresponding to a different stimulus frequency included in the plurality of stimulus frequencies, and determine, based on an amplitude and a phase of each of one or more evoked response signals included in the plurality of evoked response signals, an insertion state of the electrode lead within the cochlea of the recipient.

40. 发明申请

US20220126089A1 SYSTEMS AND METHODS FOR INTRA-SURGICAL MONITORING OF COCHLEAR TRAUMA DURING AN ELECTRODE LEAD INSERTION PROCEDURE 有权
公开(公告)号：US20220126089A1
公开(公告)日：2022-04-28
申请号：US17569894
申请日：2022-01-06
申请人： Advanced Bionics AG
发明人： Kanthaiah Koka , Leonid M. Litvak
IPC分类号： A61N1/05
摘要： An illustrative system includes a cochlear implant, a lead configured to be inserted into a cochlea of a patient by way of an insertion procedure, a plurality of electrodes disposed on the lead and including an intracochlear electrode and an extracochlear electrode, a probe coupled to the extracochlear electrode, and a processor communicatively coupled with the probe and the cochlear implant. During the insertion procedure, the processor directs the cochlear implant to short the intracochlear and extracochlear electrodes, then detects, by way of the probe and the shorted intracochlear and extracochlear electrodes, evoked responses measured at the intracochlear electrode. The evoked responses include a first evoked response measured at a first insertion depth and a second evoked response measured at a second insertion depth. The processor generates, based on the first and second evoked responses, a notification indicating that cochlear trauma has likely occurred at the second insertion depth.

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