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31. 发明申请

US20060173046A1 Hydroxypyridine cgrp receptor antagonists 审中-公开
标题翻译：羟基吡啶cgrp受体拮抗剂
公开(公告)号：US20060173046A1
公开(公告)日：2006-08-03
申请号：US10564706
申请日：2004-07-09
申请人： Ian Bell , Steven Gallicchio , C Zartman
发明人： Ian Bell , Steven Gallicchio , C Zartman
IPC分类号： A61K31/4439 , A61K31/4415 , C07D403/02
CPC分类号： C07D417/04 , C07D471/04
摘要： The present invention is directed to compounds of Formula I: I (where variables R1, R2, R3 and R4 are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to the use of such compounds as ligands of AM receptors for the treatment or prevention of diseases in which AM is involved, such as cancer. The invention is further directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP and/or AM are involved.
摘要翻译：本发明涉及式I化合物：其中变量R 1，R 2，R 3和R 4 可用作CGRP受体的拮抗剂，可用于治疗或预防涉及CGRP的疾病，例如头痛，偏头痛和丛集性头痛。本发明还涉及这样的化合物作为AM受体的配体用于治疗或预防涉及AM的疾病如癌症的用途。本发明进一步涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及CGRP和/或AM的疾病中的用途。

32. 发明授权

US06830906B2 Manganese superoxide dismutase cloning and expression in microoganisms 失效
标题翻译：锰超氧化物歧化酶克隆与表达
公开(公告)号：US06830906B2
公开(公告)日：2004-12-14
申请号：US09878589
申请日：2001-06-11
申请人： Robert Alexander Hallewell , Graeme Ian Bell , Guy Towns Mullenbach
发明人： Robert Alexander Hallewell , Graeme Ian Bell , Guy Towns Mullenbach
IPC分类号： C12N902
CPC分类号： A61K38/446 , Y02A50/473
摘要： Methods and compositions are provided for the production of human manganese superoxide dismutase and a protocol for enhancing efficiency of expression. The gene encoding for human manganese superoxide dismutase was isolated and inserted into a vector in conjunction with a synthetic linker which provides for enhanced efficiency in translation. E. coli strain HB101 containing the plasmid Nco5AHSODm was deposited at the A.T.C.C. on Oct. 3, 1986 and given Accession No. 67191.
摘要翻译：提供了用于生产人类锰超氧化物歧化酶的方法和组合物以及用于提高表达效率的方案。分离编码人锰超氧化物歧化酶的基因，并与合成接头连接插入载体，提供翻译效率更高。含有质粒Nco5AHSODm的大肠杆菌菌株HB101保藏在A.T.C.C. 1986年10月3日，加拿大号为67191。

33. 发明授权

US5488476A Apparatus and method using optical diffraction to measure surface roughness 失效
$Apparatus and method using optical diffraction to measure surface roughness$
标题翻译：使用光学衍射测量表面粗糙度的装置和方法
公开(公告)号：US5488476A
公开(公告)日：1996-01-30
申请号：US322088
申请日：1994-10-12
申请人： Daniel Mansfield , Ian Bell , Ian Buehring , Jennifer Harding
发明人： Daniel Mansfield , Ian Bell , Ian Buehring , Jennifer Harding
IPC分类号： G01B11/30 , G06T1/00 , G06T7/00 , G01B9/02
CPC分类号： G01B11/303
摘要： Apparatus for measuring surface roughness utilizes diffraction patterns derived from the surface under test. The energies in the different orders are detected and processed utilizing various different algorithms dependent upon a number of factors such as the number of orders in the diffraction pattern and asymmetry in the diffraction pattern. Various filter functions both for the diffraction pattern itself and for values of surface roughness after measurement are disclosed. One algorithm for measuring surface roughness involves comparison of values representing the energy orders with reference values, preferably reference values obtained by an interpolation operation between one set of reference values representative of a diffraction pattern from a symmetrical surface and another set representative of a diffraction pattern from an asymmetrical surface.
摘要翻译：用于测量表面粗糙度的设备利用衍射自被测表面的衍射图。使用各种不同的算法来检测和处理不同顺序的能量，这些算法取决于许多因素，例如衍射图中的阶数和衍射图中的不对称性。公开了用于衍射图案本身和测量后的表面粗糙度值的各种滤光器功能。用于测量表面粗糙度的一种算法涉及将表示能量阶数的值与参考值进行比较，优选通过表示来自对称表面的衍射图案的一组参考值与代表衍射图案的另一组之间的内插操作获得的参考值，不对称的表面。

34. 发明授权

US08127870B2 Lifting and transportation device 有权
标题翻译：起重运输装置
公开(公告)号：US08127870B2
公开(公告)日：2012-03-06
申请号：US12441103
申请日：2007-09-13
申请人： Peter Raymond March , Kenneth Ian Bell
发明人： Peter Raymond March , Kenneth Ian Bell
IPC分类号： B62D51/04
CPC分类号： A61G5/02 , A61G5/027 , A61G5/047 , A61G5/104 , B62B5/005 , B62B5/0079
摘要： An improved lifting and transportation device including an attachment means adapted to engage a wheeled device to be transported; and one or more driving wheels adapted to engage the ground to propel said lifting and a transportation device, whereby, said lifting and transportation device is steerable by the independent engagement of said driving wheels; and a controller adapted to control the motion of said driving wheels and control the operation of said attachment means. The attachment means may be an attachment assembly with laterally opposed attachment brackets adapted to engage said wheeled device, whereby, a vertical actuator is used to adjust the vertical height of said attachment assembly and a horizontal actuator is used to adjust the horizontal separation of said laterally opposed attachment brackets
摘要翻译：一种改进的提升和运输装置，包括适于接合待运输的轮式装置的附接装置; 以及一个或多个驱动轮，其适于接合地面以推动所述提升和运输装置，由此所述提升和运输装置可通过所述驱动轮的独立接合而转向; 以及控制器，其适于控制所述驱动轮的运动并控制所述附接装置的操作。附接装置可以是具有适于接合所述轮式装置的横向相对的附接支架的附接组件，由此使用垂直致动器来调节所述附接组件的垂直高度，并且使用水平致动器来调节所述横向的水平间隔相反的附件

35. 发明申请

US20100284952A1 Hair Treatment Compositions 有权
标题翻译：头发处理组合物
公开(公告)号：US20100284952A1
公开(公告)日：2010-11-11
申请号：US12086449
申请日：2006-12-07
申请人： Fraser Ian Bell , Karen Maria Devine , Ezat Khoshdel , Yann Leray , Teresa Lyons , Colina MacKay , Yvonne Christine Plant , Richard Skinner
发明人： Fraser Ian Bell , Karen Maria Devine , Ezat Khoshdel , Yann Leray , Teresa Lyons , Colina MacKay , Yvonne Christine Plant , Richard Skinner
IPC分类号： A61K8/60 , A61Q5/00 , A61Q5/12
CPC分类号： A61K8/44 , A61K8/60 , A61Q5/00
摘要： The invention provides a hair treatment composition comprising a combination of a sugar, an aliphatic amino acid and a basic amino acid. The composition is particularly suitable for the treatment of hair which is dry, damaged and/or prone to manageability problems.
摘要翻译：本发明提供了包含糖，脂肪族氨基酸和碱性氨基酸的组合的头发处理组合物。该组合物特别适用于治疗干燥，损伤和/或容易出现管理问题的头发。

36. 发明申请

US20100038154A1 Lifting and Transportation Device 有权
标题翻译：起重运输装置
公开(公告)号：US20100038154A1
公开(公告)日：2010-02-18
申请号：US12441103
申请日：2007-09-13
申请人： Peter Raymond March , Kenneth Ian Bell
发明人： Peter Raymond March , Kenneth Ian Bell
IPC分类号： A61G5/10 , A61G3/00 , B62D51/04
CPC分类号： A61G5/02 , A61G5/027 , A61G5/047 , A61G5/104 , B62B5/005 , B62B5/0079
摘要： An improved lifting and transportation device including an attachment means adapted to engage a wheeled device to be transported; and one or more driving wheels adapted to engage the ground to propel said lifting and a transportation device, whereby, said lifting and transportation device is steerable by the independent engagement of said driving wheels; and a controller adapted to control the motion of said driving wheels and control the operation of said attachment means. The attachment means may be an attachment assembly with laterally opposed attachment brackets adapted to engage said wheeled device, whereby, a vertical actuator is used to adjust the vertical height of said attachment assembly and a horizontal actuator is used to adjust the horizontal separation of said laterally opposed attachment brackets
摘要翻译：一种改进的提升和运输装置，包括适于接合待运输的轮式装置的附接装置; 以及一个或多个驱动轮，其适于接合地面以推动所述提升和运输装置，由此所述提升和运输装置可通过所述驱动轮的独立接合而转向; 以及控制器，其适于控制所述驱动轮的运动并控制所述附接装置的操作。附接装置可以是具有适于接合所述轮式装置的横向相对的附接支架的附接组件，由此使用垂直致动器来调节所述附接组件的垂直高度，并且使用水平致动器来调节所述横向的水平间隔相反的附件

37. 发明申请

US20080004304A1 Aryl Spirolactam Cgrp Receptor Antagonists 有权
标题翻译：芳基己内酰胺Cgrp受体拮抗剂
公开(公告)号：US20080004304A1
公开(公告)日：2008-01-03
申请号：US11662424
申请日：2005-09-06
申请人： Ian Bell , Craig Stump , Cory Theberge
发明人： Ian Bell , Craig Stump , Cory Theberge
IPC分类号： A61K31/40 , A61K31/437 , A61P25/06 , C07D209/54 , C07D487/04
CPC分类号： C07D209/96 , C07D471/04 , C07D487/04
摘要： The present invention is directed to compounds of Formula (I): where variables A1, A2, B, J, K, m, n, R4, R5a, R5a, R5c and X are as defined herein useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
摘要翻译：本发明涉及式（I）的化合物：其中变量A 1，A 2，B，J，K，m，n，R 4 R 5a，R 5a，R 5c和X如本文所定义，可用作CGRP受体的拮抗剂，并且可用于治疗或预防CGRP涉及的疾病，如头痛，偏头痛和丛集性头痛。本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及CGRP的疾病中的用途。

38. 发明申请

US20060281645A1 Lubricating oil compositions 有权
公开(公告)号：US20060281645A1
公开(公告)日：2006-12-14
申请号：US11436778
申请日：2006-05-18
申请人： Ian Bell , Robert Shaw
发明人： Ian Bell , Robert Shaw
IPC分类号： C10M159/22
CPC分类号： C10M159/22 , C10M2207/262 , C10N2210/02 , C10N2230/06 , C10N2230/42 , C10N2230/45 , C10N2230/52 , C10N2240/10
摘要： An internal combustion engine crankcase lubricating oil composition has a phosphorus content of not greater than 0.08 mass % and a metal detergent additive system comprising a calcium salicylate and a magnesium salicylate and having a mass ratio of magnesium atoms to calcium atoms of greater than one.

39. 发明申请

US20060185865A1 Actuation apparatus for power tool 审中-公开
公开(公告)号：US20060185865A1
公开(公告)日：2006-08-24
申请号：US11359167
申请日：2006-02-22
申请人： Achim Jung , Rene Jager , Ian Bell
发明人： Achim Jung , Rene Jager , Ian Bell
IPC分类号： E02D7/02
CPC分类号： B25D16/006 , B25D2216/0015 , B25D2216/0023 , B25D2216/0038 , B25D2250/221 , B25D2250/261 , H01H9/06
摘要： When the mode change knob of a multi-mode hammer drill is moved to the hammer only position, an electronic sensor sends a signal to a control logic circuit. When the user then depresses the trigger mechanically closing the ON/OFF switch, the control logic circuit applies a voltage either to a holding relay or to the gate of a triac which enables the relay or triac to conduct, thus providing a parallel circuit by-passing the ON/OFF switch. Consequently, when the user releases the trigger and opens the ON/OFF switch, the parallel relay or triac maintains current flow to the motor. It can be seen that in hammer only mode the user can activate the hammer drill by simply tapping the trigger to depress it and does not need to hold down trigger during use of the hammer in operation.

40. 发明申请

US20060105925A1 Lubricating oil additive concentrates 有权
标题翻译：润滑油添加剂浓缩液
公开(公告)号：US20060105925A1
公开(公告)日：2006-05-18
申请号：US11266874
申请日：2005-11-04
申请人： Raymond Fellows , Ian Bell
发明人： Raymond Fellows , Ian Bell
IPC分类号： C09K15/08
CPC分类号： C10M163/00 , C10M169/045 , C10M2207/024 , C10M2207/028 , C10M2207/26 , C10M2207/262 , C10M2207/282 , C10M2207/283 , C10M2215/042 , C10M2215/225 , C10M2219/046 , C10N2210/02 , C10N2230/00
摘要： Lubricating oil additive concentrates containing oil of lubricating viscosity, at least one basic metal complex, an oil-soluble hydrocarbyl phenol aldehyde condensate, and an organic friction modifier containing at least one hydroxyl and/or amino group.
摘要翻译：含有润滑粘度油的润滑油添加剂浓缩物，至少一种碱金属络合物，油溶性烃基酚醛缩合物和含有至少一个羟基和/或氨基的有机摩擦改进剂。

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