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31. 发明申请

US20140038975A1 Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents 有权
标题翻译：咪唑，吡唑和三唑衍生物作为抗菌剂有用
公开(公告)号：US20140038975A1
公开(公告)日：2014-02-06
申请号：US14110165
申请日：2012-03-27
申请人： Matthew Frank Brown , Jinshan Michael Chen , Michael Joseph Melnick , Justin Ian Montgomery , Usa Reilly
发明人： Matthew Frank Brown , Jinshan Michael Chen , Michael Joseph Melnick , Justin Ian Montgomery , Usa Reilly
IPC分类号： C07D413/10 , C07D249/06 , C07D413/04 , C07D233/61 , C07D231/12 , C07D403/04
CPC分类号： C07D413/10 , A61K31/4192 , C07D231/12 , C07D233/61 , C07D249/06 , C07D403/04 , C07D405/04 , C07D413/04 , C07D417/04 , Y02A50/473
摘要： The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.
摘要翻译：本发明涉及一类新的异羟肟酸衍生物，它们用作LpxC抑制剂，更具体地，其用于治疗细菌感染。

32. 发明申请

US20120258948A1 N-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents 有权
标题翻译：用作抗菌剂的N-连接的羟肟酸衍生物
公开(公告)号：US20120258948A1
公开(公告)日：2012-10-11
申请号：US13515607
申请日：2010-12-06
申请人： Matthew Frank Brown , Ye Che , Anthony Marfat , Michael Joseph Melnick , Justin Ian Montgomery , Usa Reilly
发明人： Matthew Frank Brown , Ye Che , Anthony Marfat , Michael Joseph Melnick , Justin Ian Montgomery , Usa Reilly
IPC分类号： A61K31/4412 , A61K31/4439 , C07D213/64 , C07D401/12 , A61K31/4545 , A61K31/4418 , C07D405/10 , A61K31/4433 , A61K31/506 , C07D413/10 , C07D213/643 , A61K31/444 , A61K31/4709 , A61K31/4427 , C07D401/14 , C07D417/12 , A61K31/541 , C07D413/12 , A61K31/5377 , A61P31/04 , C07D401/10
CPC分类号： A61K31/4412 , A61K31/4439 , C07D211/86 , C07D213/64 , C07D401/04 , C07D401/08 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/04 , C07D405/10 , C07D409/04 , C07D413/10 , C07D413/12 , C07D417/04 , C07D417/10 , C07D417/12 , Y02A50/473
摘要： The present invention is directed to a new class of hydroxamic acid derivatives of formula I, wherein the variables G, T, D, L, R1, R2, R3 are as described herein, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections in a patient in need thereof.
摘要翻译：本发明涉及一类新的式I的异羟肟酸衍生物，其中变量G，T，D，L，R 1，R 2，R 3如本文所述，它们作为LpxC抑制剂的用途，更具体地说，在有需要的患者中治疗细菌感染。

33. 发明申请

US20100291907A1 SYSTEMS AND METHOD FOR TRIGGERING LOCATION BASED VOICE AND/OR DATA COMMUNICATIONS TO OR FROM MOBILE RATIO TERMINALS 有权
标题翻译：用于触发基于位置的语音和/或数据通信到移动终端的系统和方法
公开(公告)号：US20100291907A1
公开(公告)日：2010-11-18
申请号：US12733724
申请日：2008-09-17
申请人： Malcolm David MacNaughtan , Christopher Ridgway Drane , Craig Andrew Scott , Stephen Frank Brown
发明人： Malcolm David MacNaughtan , Christopher Ridgway Drane , Craig Andrew Scott , Stephen Frank Brown
IPC分类号： H04W4/02 , A63F9/24 , G06Q30/00
CPC分类号： G06Q30/0241 , H04L67/04 , H04L67/18 , H04L67/20 , H04M3/4878 , H04W4/02 , H04W4/021 , H04W4/21 , H04W8/20
摘要： Systems, methods and devices for monitoring the location of mobile radio terminal users for the purpose of detecting when they approach within range of one or more target locations in order to trigger voice and/or data communications to or from the network or other mobile radio terminals.
摘要翻译：用于监视移动无线终端用户的位置的系统，方法和设备，用于检测何时它们在一个或多个目标位置的范围内接近以触发到网络或其他移动无线电终端的语音和/或数据通信。

34. 发明申请

US20100248640A1 METHODS AND SYSTEMS FOR ZONE CREATION AND ADAPTION 有权
标题翻译：区域创建和适应的方法和系统
公开(公告)号：US20100248640A1
公开(公告)日：2010-09-30
申请号：US12734812
申请日：2008-11-26
申请人： Malcolm David MacNaughtan , Christopher Ridgway Drane , Stephen Frank Brown , Craig Andrew Scott
发明人： Malcolm David MacNaughtan , Christopher Ridgway Drane , Stephen Frank Brown , Craig Andrew Scott
IPC分类号： H04B17/00
CPC分类号： H04W4/02 , H04W8/18
摘要： Methods and systems of updating a zone profile comprising obtaining a plurality of radio signal parameter measurements and, if the plurality of radio signal parameter measurements contains at least one measurement corresponding to a dominant element of the zone profile and if the plurality of radio signal parameter measurements contains at least one measurement corresponding to a candidate element (e.g., statistically unlikely element) of the zone profile, updating the profile by either adjusting an existing parameter value or by adding a new element to the zone profile corresponding to the candidate element.
摘要翻译：更新区域简档的方法和系统包括获得多个无线电信号参数测量值，并且如果所述多个无线电信号参数测量值包含对应于所述区域简档的主要元素的至少一个测量值，并且如果所述多个无线电信号参数测量值包含对应于区域轮廓的候选元素（例如，统计上不可能的元素）的至少一个测量值，通过调整现有参数值或通过将新元素添加到与候选元素相对应的区域轮廓来更新轮廓。

35. 发明申请

US20100120794A1 Cycloalkylamino Acid Derivatives 审中-公开
标题翻译：环烷基氨基酸衍生物
公开(公告)号：US20100120794A1
公开(公告)日：2010-05-13
申请号：US12651885
申请日：2010-01-04
申请人： Samit Kumar Bhattacharya , Matthew Frank Brown , Peter Hans Dorff , Susan LaGreca
发明人： Samit Kumar Bhattacharya , Matthew Frank Brown , Peter Hans Dorff , Susan LaGreca
IPC分类号： A61K31/497 , C07D413/04 , A61K31/4439 , C07D417/04 , A61P37/00 , A61P19/02 , A61P3/10 , A61P1/00 , A61P29/00 , A61P11/06 , A61P9/10 , A61K31/506 , C07D271/06 , A61K31/4245 , A61K31/4436
CPC分类号： C07D213/38 , C07D271/06 , C07D271/10 , C07D271/107 , C07D401/04 , C07D413/04 , C07D417/04
摘要： The invention relates to compounds of formula I and to pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof; wherein B, D, E, R1, R2, R3, R4, R5, R8, m, n, p, q, r, s, t and u are as defined herein. This invention also relates to a method of using such compounds in the treatment of hyperproliferative diseases and autoimmune diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
摘要翻译：本发明涉及式I化合物及其药学上可接受的盐，前体药物，溶剂合物或水合物; 其中B，D，E，R 1，R 2，R 3，R 4，R 5，R 8，m，n，p，q，r，s，t和u如本文所定义。本发明还涉及使用这些化合物治疗哺乳动物，特别是人类的过度增殖性疾病和自身免疫性疾病的方法，以及含有这些化合物的药物组合物。

36. 发明申请

US20070174438A9 Notification system 审中-公开
标题翻译：通知系统
公开(公告)号：US20070174438A9
公开(公告)日：2007-07-26
申请号：US10734725
申请日：2003-12-12
申请人： Daniel Johnson , James Peterson , Robert McConnell , Frank Brown
发明人： Daniel Johnson , James Peterson , Robert McConnell , Frank Brown
IPC分类号： G06F15/173
CPC分类号： G05B15/02
摘要： A system for receiving and normalizing notification events from assets or equipment located at various sites within an enterprise is disclosed. The system includes receiving a notification, identifying the protocol used by the equipment sending the notification, and converting the notification to a normalized format. The system allows notifications from various types of equipment or assets to be handled by one enterprise management system.
摘要翻译：披露了一种系统，用于从位于企业内各个场所的资产或设备接收和规范化通知事件。该系统包括接收通知，识别由发送通知的设备使用的协议，并将该通知转换为归一化格式。该系统允许来自各种类型的设备或资产的通知由一个企业管理系统来处理。

37. 发明申请

US20060130501A1 Variable speed condenser fan control system 有权
标题翻译：变速冷凝器风机控制系统
公开(公告)号：US20060130501A1
公开(公告)日：2006-06-22
申请号：US11260878
申请日：2005-10-27
申请人： Abtar Singh , Thomas Mathews , Frank Brown , Ozgur Gurkan
发明人： Abtar Singh , Thomas Mathews , Frank Brown , Ozgur Gurkan
IPC分类号： F25B39/04
CPC分类号： F25B49/027 , F25B2400/075 , F25B2400/22 , F25B2600/111 , F25B2700/15 , F25B2700/151 , F25B2700/1931 , F25B2700/1933 , F25B2700/195 , F25B2700/2106 , F25B2700/21151 , F25B2700/2116 , Y02B30/743
摘要： A controller comprises a first input that receives a signal indicating an energy consumption value of a compressor, a second input that receives a signal indicating an energy consumption value of a variable speed condenser fan, and an output that provides a control signal to the variable speed condenser fan. The controller also comprises a memory that stores a condenser set point, and a processor in communication with the input, output and memory and that modulates the condenser set-point to minimize energy consumption and controls the variable speed condenser fan based on the condenser set-point.
摘要翻译：控制器包括接收指示压缩机的能量消耗值的信号的第一输入端，接收指示可变速冷凝器风扇的能量消耗值的信号的第二输入端以及向变速器提供控制信号的输出冷凝器风扇控制器还包括存储冷凝器设定点的存储器和与输入，输出和存储器通信的处理器，并且调节冷凝器设定点以最小化能量消耗，并且基于冷凝器设定点控制可变速冷凝器风扇，点。

38. 发明申请

US20050203092A1 4-Pyrimidinamine derivatives, pharmaceutical compositions and related methods 审中-公开
标题翻译： 4-嘧啶胺衍生物，药物组合物和相关方法
公开(公告)号：US20050203092A1
公开(公告)日：2005-09-15
申请号：US10987562
申请日：2004-11-12
申请人： Elfrida Benjamin , Frank Brown , Robert Zivin , Michael McMillan , Zhong Zhong , Allen Reitz , Tina Ross
发明人： Elfrida Benjamin , Frank Brown , Robert Zivin , Michael McMillan , Zhong Zhong , Allen Reitz , Tina Ross
IPC分类号： C07D239/12 , C07D239/42 , C07D239/52 , C07D401/12 , C07D405/04 , C07D409/04 , C07D495/04 , C07D413/02 , A61K31/506 , A61K31/5377 , C07D43/02
CPC分类号： C07D239/42 , C07D239/12 , C07D239/52 , C07D401/12 , C07D405/04 , C07D409/04 , C07D495/04
摘要： This invention provides novel neuroprotective 4-pyrimidineamine derivatives and neuroprotective pharmaceutical compositions comprising 4-pyrimidinamines. This invention also provides methods of using these compositions to prevent ischemic cell death, particularly neuronal cell death, and reduce the likelihood of neuronal cell death in a subject due to a traumatic event. Finally, this invention provides an apparatus for administering to a subject the instant pharmaceutical compositions.
摘要翻译：本发明提供新颖的神经保护性4-嘧啶胺衍生物和包含4-嘧啶胺的神经保护药物组合物。本发明还提供了使用这些组合物来预防缺血性细胞死亡，特别是神经元细胞死亡并降低由于创伤性事件导致受试者神经元细胞死亡的可能性的方法。最后，本发明提供了一种向受试者施用本发明的药物组合物的装置。

39. 植物专利

USPP11306P Aglaonema plant named `Cassandra` 失效
公开(公告)号：USPP11306P
公开(公告)日：2000-03-21
申请号：US114123
申请日：1998-07-13
申请人： B. Frank Brown , Cleofar P. Millare
发明人： B. Frank Brown , Cleofar P. Millare
摘要： A new and distinct cultivar of Aglaonema named `Cassandra` particularly characterized by its upright and outwardly arching plant habit; uniform plant habit; good production of divisions; short internodes with numerous leaves giving plants a very full and dense appearance; upper leaf surfaces that are glossy silver green with dark green random spots and whitish-green to white midrib; large, oblong, flat leaves with white petioles which contrast well with the leaves; tolerance to low temperatures; and resistance to diseases common to Aglaonema.

40. 发明授权

US06006465A Fishing lure harness system 失效
标题翻译：钓鱼诱饵系统
公开(公告)号：US06006465A
公开(公告)日：1999-12-28
申请号：US982565
申请日：1997-12-02
申请人： Frank Brown , Richard W. Brown , Richard M. Brown
发明人： Frank Brown , Richard W. Brown , Richard M. Brown
IPC分类号： A01K85/00
CPC分类号： A01K85/00
摘要： A soft-bodied crank-bait lure comprising a rigid interior skeleton and a rubbery body molded or formed thereover, where the skeleton includes: a first channel extending downward and rearward from the anterior end of the lure; and a second channel extending downward and forward from the posterior end of the lure. The rearward opening of the first channel is spaced from and substantially faces the forward opening of the second channel, and the first channel and the second channel are angled with respect to each other. Fishing line or leader line is threaded through the first channel and then through second channel, and the hooks are coupled to the line rather than to the skeleton or to the rubbery body. Therefore, the lure will "free-flow" on the line, so that when a fish strikes the lure and becomes hooked, the lure will slide away from the fish. Furthermore, during the ensuing fight, when the line becomes taut, the angled alignment between the first and second channels will cause the lure will become substantially "locked" onto the line away from the fish.
摘要翻译：柔软的曲柄诱饵包括刚性内部骨架和模制或形成在其上的橡胶体，其中骨架包括：从诱饵的前端向下和向后延伸的第一通道; 以及从诱饵的后端向下和向前延伸的第二通道。第一通道的向后开口与第二通道的前开口间隔开并且基本上面对第二通道的前开口，并且第一通道和第二通道相对于彼此成角度。钓鱼线或引导线穿过第一通道，然后穿过第二通道，并且钩被联接到线而不是骨架或橡胶体。因此，诱惑会“自由流通”，所以当一只鱼撞上诱惑并被钩住时，诱惑会从鱼身上滑落。此外，在随后的战斗中，当线条拉紧时，第一和第二通道之间的成角度对准将导致诱饵将基本上“锁定”在远离鱼的线上。

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