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31. 发明申请

US20140336676A1 TISSUE LIGATION DEVICES AND METHODS THEREFOR 审中-公开
标题翻译：组织注射装置及其方法
公开(公告)号：US20140336676A1
公开(公告)日：2014-11-13
申请号：US14272478
申请日：2014-05-07
申请人： SENTREHEART, INC.
发明人： Russell PONG , Robert L. CLARK, III , Gregory W. FUNG , Arnold M. ESCANO
IPC分类号： A61B17/12
CPC分类号： A61B17/12013 , A61B2017/00243
摘要： Described here are closure devices and methods for ligating tissue, such as the left atrial appendage. The closure devices may comprise a snare loop assembly comprising a snare and a suture loop releasably attached thereto, and a snare control. The closure devices may further comprise one or more reference markings, wherein the relative positioning between a portion of the snare control and the reference markings provides an indication of the diameter of the snare loop assembly. In some variations, when the snare loop assembly is closed around a tissue such as the left atrial appendage, the measured diameter of the snare loop assembly may help a user determine whether the snare loop assembly has been properly positioned relative to the tissue, as well as the approximate size that a suture loop may have when released from the snare loop assembly.
摘要翻译：这里描述了用于结扎组织的闭合装置和方法，例如左心耳。闭合装置可以包括圈套组件，其包括可释放地附接到其上的圈套和缝合线环以及圈套控制。闭合装置还可以包括一个或多个参考标记，其中圈套控制部分和参考标记之间的相对定位提供了圈套环组件的直径的指示。在一些变型中，当围绕诸如左心耳的组织围绕圈套环组件时，圈套环组件的测量直径可以帮助用户确定圈圈组件是否已经相对于组织正确定位作为当从圈套环组件释放时缝合线圈可能具有的大致尺寸。

32. 发明申请

US20080147097A1 APPARATUS AND METHOD FOR THE LIGATION OF TISSUE 有权
公开(公告)号：US20080147097A1
公开(公告)日：2008-06-19
申请号：US12037802
申请日：2008-02-26
申请人： John R. LIDDICOAT , William E. Cohn , Roger Laham
发明人： John R. LIDDICOAT , William E. Cohn , Roger Laham
IPC分类号： A61B17/12 , A61M29/00
CPC分类号： A61B17/12013 , A61B17/00234 , A61B17/0467 , A61B17/12009 , A61B17/30 , A61B2017/00243 , A61B2017/00867 , A61B2017/00876 , A61B2017/12018 , A61B2017/308 , A61B2090/0811 , A61B2090/3966 , A61B2576/023 , A61F2/013 , A61F2230/0006 , A61F2230/005 , A61M25/0108 , A61M25/0127 , A61M25/10 , A61M29/02
摘要： A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

33. 发明申请

US20070073313A1 Apparatus and method for the ligation of tissue 有权
标题翻译：用于结扎组织的装置和方法
公开(公告)号：US20070073313A1
公开(公告)日：2007-03-29
申请号：US11600671
申请日：2006-11-15
申请人： John Liddicoat , William Cohn , Roger Laham
发明人： John Liddicoat , William Cohn , Roger Laham
IPC分类号： A61B17/10
CPC分类号： A61B17/12013 , A61B17/00234 , A61B17/0467 , A61B17/12009 , A61B17/30 , A61B2017/00243 , A61B2017/00867 , A61B2017/00876 , A61B2017/12018 , A61B2017/308 , A61B2090/0811 , A61B2090/3966 , A61B2576/023 , A61F2/013 , A61F2230/0006 , A61F2230/005 , A61M25/0108 , A61M25/0127 , A61M25/10 , A61M29/02
摘要： A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.
摘要翻译：一种新颖的基于导管的系统，其将心脏外侧的左心耳（LAA）结合，优选地使用导管和/或器械的组合，例如位于左心耳内的引导导管，其可以协助定位左心耳和/或辅助将附件最佳放置在附肢的外侧，以及在心包空间内的心脏外的结扎导管和/或器械，以将结扎元件设置在左心耳的颈部。

34. 发明授权

US11020122B2 Methods for closing the left atrial appendage 有权
公开(公告)号：US11020122B2
公开(公告)日：2021-06-01
申请号：US15634982
申请日：2017-06-27
申请人： SentreHEART, Inc.
发明人： Gary H. Miller , Russell A. Seiber , Gregory W. Fung
IPC分类号： A61B17/12 , A61B17/04 , A61M25/10 , A61B17/00 , A61B90/00
摘要： Described here are devices, systems and methods for closing the left atrial appendage. Some of the methods described here utilize one or more guide members having alignment members to aid in positioning of a closure device. In general, these methods include advancing a first guide having a first alignment member into the left atrial appendage, advancing a second guide, having a second alignment member, into the pericardial space, aligning the first and second alignment members, advancing a left atrial appendage closure device into the pericardial space and adjacent to the left atrial appendage, and closing the left atrial appendage with the closure device. In these variations, the closure device typically has an elongate body having a proximal end and a distal end, and a closure element at least partially housed within the elongate body. The closure element comprises a loop defining a continuous aperture therethrough.

35. 发明授权

US10966725B2 Devices and systems for closing the left atrial appendage 有权
公开(公告)号：US10966725B2
公开(公告)日：2021-04-06
申请号：US14625540
申请日：2015-02-18
申请人： SentreHEART, Inc.
发明人： Gary H. Miller , Russell A. Seiber , Gregory W. Fung
IPC分类号： A61B17/12 , A61B17/04 , A61M25/10 , A61B17/00 , A61B90/00
摘要： Described here are devices, systems and methods for closing the left atrial appendage. Some of the methods described here utilize one or more guide members having alignment members to aid in positioning of a closure device. In general, these methods include advancing a first guide having a first alignment member into the left atrial appendage, advancing a second guide, having a second alignment member, into the pericardial space, aligning the first and second alignment members, advancing a left atrial appendage closure device into the pericardial space and adjacent to the left atrial appendage, and closing the left atrial appendage with the closure device. In these variations, the closure device typically has an elongate body having a proximal end and a distal end, and a closure element at least partially housed within the elongate body. The closure element comprises a loop defining a continuous aperture therethrough.

36. 发明授权

US10327780B2 Apparatus and method for the ligation of tissue 有权
公开(公告)号：US10327780B2
公开(公告)日：2019-06-25
申请号：US15041777
申请日：2016-02-11
申请人： SentreHEART, Inc.
发明人： John R. Liddicoat , William E. Cohn , Roger Laham
IPC分类号： A61F2/01 , A61B17/00 , A61B17/04 , A61B17/12 , A61B17/30 , A61B90/00 , A61M25/01 , A61M25/10 , A61M29/02
摘要： A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

37. 发明授权

US10292710B2 Devices and methods for left atrial appendage closure 有权
公开(公告)号：US10292710B2
公开(公告)日：2019-05-21
申请号：US15442216
申请日：2017-02-24
申请人： SentreHEART, Inc.
发明人： Robert L. Clark, III , Alan L. Bradley , Gregory W. Fung
IPC分类号： A61B17/04 , A61B17/12 , A61B17/3205 , A61B17/221 , A61B90/00
摘要： Closure devices and methods are provided for ligating tissue, such as the left atrial appendage. Generally, the closure devices include an elongate body, a snare loop assembly comprising a snare and a suture loop, and a shuttle connected to the snare and releasably coupled to the elongate body and retractable therein. In some variations, the shuttle may be configured to fit into the lumen. In other variations, a handle may be attached to the elongate body, and the handle may comprise a track and a snare control coupled to the track. The handle may be configured to release the shuttle from the elongate body and allow movement of the snare control along the track to retract the snare loop and the shuttle into a lumen of the elongate body.

38. 发明授权

US10258408B2 Devices and methods for left atrial appendage closure 有权
公开(公告)号：US10258408B2
公开(公告)日：2019-04-16
申请号：US14530575
申请日：2014-10-31
申请人： SentreHEART, Inc.
发明人： Gregory W. Fung , Randall J. Lee , Russell Pong , Robert L. Clark, III , Arnold M. Escano
IPC分类号： A61B18/00 , A61B18/14 , A61B17/12 , A61B17/00
摘要： Described here are devices, systems, and methods for closing the left atrial appendage. The methods described here utilize a closure device for closing the left atrial appendage and guides or expandable elements with ablation or abrading elements to ablate or abrade the left atrial appendage. In general, these methods include positioning a balloon at least partially within the atrial appendage, positioning a closure assembly of a closure device around an exterior of the atrial appendage, inflating the balloon, partially closing the closure assembly, ablating the interior tissue of the atrial appendage with the inflated balloon, removing the balloon from the atrial appendage, and closing the atrial appendage with the closure assembly.

39. 发明授权

US09604053B2 Methods and apparatus for lead placement on a surface of the heart 有权
公开(公告)号：US09604053B2
公开(公告)日：2017-03-28
申请号：US13271908
申请日：2011-10-12
申请人： Aaron V. Kaplan , Kevin F. Hahnen
发明人： Aaron V. Kaplan , Kevin F. Hahnen
IPC分类号： A61N1/05
CPC分类号： A61N1/0587 , A61N2001/0578
摘要： The methods and apparatus for lead placement on a surface of the heart are employed using an elongated body having proximal and distal end portions. The body defines a lead receiving passageway extending between a proximal inlet and a distal outlet for receiving a lead therethrough for contact with the heart surface. The elongated body is adapted for insertion between a pericardium and an epicardial surface. At least a portion of the body may have a non-circular cross-sectional shape adapted to retain the body orientation between the pericardium and the epicardial surface.

40. 发明授权

US09522006B2 Apparatus and method for the ligation of tissue 有权
公开(公告)号：US09522006B2
公开(公告)日：2016-12-20
申请号：US13033532
申请日：2011-02-23
申请人： John R. Liddicoat , William E. Cohn
发明人： John R. Liddicoat , William E. Cohn
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/12013 , A61B17/00234 , A61B2017/00243
摘要： A novel catheter-based system that ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter inserted into the interior of the left atrial appendage that may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature or constricting element on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set the ligature or constricting element at the neck of the left atrial appendage.

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