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31. 发明授权

US07371251B2 Stretch resistant embolic coil delivery system with mechanical release mechanism 有权
标题翻译：具有机械释放机制的抗拉伸栓塞线圈输送系统
公开(公告)号：US07371251B2
公开(公告)日：2008-05-13
申请号：US11143052
申请日：2005-06-02
申请人： Vladimir Mitelberg , Donald K. Jones , Juan A. Lorenzo
发明人： Vladimir Mitelberg , Donald K. Jones , Juan A. Lorenzo
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/1205 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. A stretch resistant embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. The engagement member engages a retaining ring on the embolic device. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.
摘要翻译：一种用于将栓塞装置放置在身体的容器内的预定位置处的医疗装置，包括输送导管和具有通过其的腔的柔性推动器构件，并且可滑动地设置在导管的腔内。弹性阻塞栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括接合构件，该接合构件附接到推动器构件的远端并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。接合构件接合栓塞装置上的保持环。当栓塞装置前进到血管内的预定位置时，分离构件从孔中取出，从而在治疗部位释放栓塞装置。

32. 发明授权

US07367987B2 Stretch resistant embolic coil delivery system with mechanical release mechanism 有权
标题翻译：具有机械释放机制的抗拉伸栓塞线圈输送系统
公开(公告)号：US07367987B2
公开(公告)日：2008-05-06
申请号：US11301865
申请日：2005-12-12
申请人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , Darren R. Sherman , John H. Thinnes, Jr.
发明人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , Darren R. Sherman , John H. Thinnes, Jr.
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00477 , A61B2017/00862 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.
摘要翻译：一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。推动器构件从推动器构件的远端延伸并且被偏压以便将保持环从接合构件提起，以确保当分离构件从接合构件的孔中取出时栓塞装置的释放。

33. 发明授权

US07244261B2 Activatable bioactive vascular occlusive device 有权
标题翻译：可活化生物活性血管闭塞装置
公开(公告)号：US07244261B2
公开(公告)日：2007-07-17
申请号：US10874023
申请日：2004-06-22
申请人： Juan A. Lorenzo , Mark L. Pomeranz , Darren Sherman
发明人： Juan A. Lorenzo , Mark L. Pomeranz , Darren Sherman
IPC分类号： A61B17/08
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1215 , A61B2017/00004 , A61B2017/00336 , A61B2017/00831
摘要： A vascular occlusive device, such as an embolic coil, having thrombogenic fibers extending from the coil and having an outer barrier which encapsulates fibers extending from the embolic coil for preventing activation of the fibers until the outer barrier has been dissolved, or removed, from the embolic coil.
摘要翻译：血管闭塞装置，例如栓塞线圈，具有从线圈延伸的血栓形成纤维，并且具有封闭从栓塞线圈延伸的纤维的外屏障，用于防止纤维的活化，直到外部屏障已经被溶解或去除栓塞线圈

34. 发明授权

US07201768B2 Method and device for retrieving embolic coils 有权
标题翻译：检测栓塞线圈的方法和装置
公开(公告)号：US07201768B2
公开(公告)日：2007-04-10
申请号：US10693246
申请日：2003-10-24
申请人： Roberto Diaz , Vladimir Mitelberg
发明人： Roberto Diaz , Vladimir Mitelberg
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/076 , A61B17/12113 , A61B17/1214 , A61B17/221 , A61B17/282 , A61B17/30 , A61B90/39 , A61B2017/1205 , A61B2017/22035 , A61B2017/2215 , A61B2017/2825
摘要： A method and device are disclosed for retrieving embolic coils used for treating an aneurysm of a patient. The method comprises the steps of providing a wire device that is pushable through a microcatheter and has a flexible distal portion comprising distal collapsible arms with a latch member carried by one of the arms. The microcatheter is introduced into a patient's vessel leading to the aneurysm. The wire device, distal end first, is introduced into the microcatheter whereby the arms collapse while they are within the microcatheter. The distal end of the wire device is pushed through the microcatheter whereby the arms open when they extend out of the distal end of the microcatheter. The latch member is manipulated so that it engages an embolic coil to be retrieved. The latch-engaged embolic coil and wire device are withdrawn through the catheter, whereby the arms become collapsed as the arm is withdrawn through the catheter, securing the latch and the embolic coil.
摘要翻译：公开了用于回收用于治疗患者的动脉瘤的栓塞线圈的方法和装置。该方法包括以下步骤：提供可推动穿过微导管的线装置，并且具有柔性远端部分，其包括具有由一个臂承载的闩锁构件的远端可折叠臂。将微导管引入导致动脉瘤的患者血管。导线装置首先将远端引入微导管，由此臂在微导管内部折叠。导线装置的远端被推动通过微导管，由此当它们从微导管的远端延伸出来时，手臂打开。锁闩构件被操纵以使其与待检索的栓塞线圈接合。通过导管将闩锁接合的栓塞线圈和线装置撤回，由此当手臂通过导管撤回时，手臂变得收缩，固定闩锁和栓塞线圈。

35. 发明授权

US07195648B2 Intravascular stent device 有权
标题翻译：血管内支架装置
公开(公告)号：US07195648B2
公开(公告)日：2007-03-27
申请号：US10425380
申请日：2003-04-29
申请人： Donald K. Jones , Vladimir Mitelberg
发明人： Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/91 , A61B17/12022 , A61B17/12118 , A61B2017/1205 , A61F2/915 , A61F2002/3008 , A61F2002/823 , A61F2002/8486 , A61F2002/91541 , A61F2002/91558 , A61F2002/9534 , A61F2230/0013 , A61F2250/0098
摘要： Disclosed is a very small diameter intravascular stent, or aneurysm cover, which may be used to occlude, or partially occlude, an aneurysm in the human brain. The stent is comprised of a thin-walled skeletal tubular member formed of interconnected sinusoidal members to thereby form a pattern of cells along the skeletal tubular member. The stent also includes anchor members, which are comprised of a longitudinal leg member having a radiopaque coil disposed about the leg member, which serve to retain the stent during delivery of the stent.
摘要翻译：公开了一种非常小直径的血管内支架或动脉瘤盖，其可用于阻塞或部分闭塞人脑中的动脉瘤。支架包括由互连的正弦构件形成的薄壁骨架管状构件，从而沿着骨架管状构件形成细胞图案。支架还包括锚构件，其包括具有围绕腿构件设置的不透射线圈的纵向腿构件，其用于在支架输送期间保持支架。

36. 发明授权

US07083632B2 Aneurysm embolic device with an occlusive member 有权
公开(公告)号：US07083632B2
公开(公告)日：2006-08-01
申请号：US10295196
申请日：2002-11-15
申请人： Ernesto Avellanet , Robert Lulo
发明人： Ernesto Avellanet , Robert Lulo
IPC分类号： A61B17/08
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12172 , A61B17/1219 , A61B2017/00539 , A61B2017/1205
摘要： An aneurysm embolic device is disclosed for use in occluding the flow of blood within an aneurysm. The aneurysm embolic device includes an expandable sealing member having a circular joining member and reinforcing spokes which give the sealing member a slightly cupped configuration. The embolic device also includes an occlusive member carried by the expandable sealing member. When the aneurysm embolic device is deployed within the aneurysm, the sealing member expands and the occlusive member fills the aneurysm preventing the flow of blood within the aneurysm.

37. 发明授权

US07001422B2 Expandable stent and delivery system 有权
标题翻译：可扩展支架和输送系统
公开(公告)号：US07001422B2
公开(公告)日：2006-02-21
申请号：US10365282
申请日：2003-02-12
申请人： Angeli Escamilla , Donald K. Jones , Vladimir Mitelberg
发明人： Angeli Escamilla , Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B2017/1205 , A61F2/915 , A61F2/95 , A61F2/966 , A61F2002/823 , A61F2002/8486 , A61F2002/91533 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/9665 , A61F2250/0098
摘要： An expandable stent and delivery system is provided for enhancing luminal dilation of a blood vessel and treating aneurysms. The delivery system includes proximal, intermediate and distal cylindrical members disposed on and spaced apart along an elongated core member such that first and second gaps are formed. The expandable stent includes anchor members which align with the gaps. The expandable stent is mounted on the intermediate cylindrical member, and the anchor members are disposed within the gaps thereby locking the stent onto the core member.
摘要翻译：提供可扩张的支架和递送系统用于增强血管的腔内扩张和治疗动脉瘤。输送系统包括近似的，中间的和远端的圆柱形部件，其沿着细长的芯部件设置在并间隔开，使得形成第一和第二间隙。可扩张支架包括与间隙对准的锚定构件。可扩张支架安装在中间圆柱形构件上，并且锚定构件设置在间隙内，从而将支架锁定在芯构件上。

38. 发明授权

US06989020B2 Embolic coil retrieval system 有权
公开(公告)号：US06989020B2
公开(公告)日：2006-01-24
申请号：US10252615
申请日：2002-09-23
申请人： Donald K. Jones , Vladimir Mitelberg
发明人： Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61M29/00
CPC分类号： A61B17/22031 , A61B17/221 , A61B2017/2215 , A61B2017/301
摘要： An embolic coil retrieval system for retrieving or repositioning an embolic coil within the vasculature of the human body which is comprised of a very small embolic coil retriever having a jaw member with major and minor teeth which form pockets for grasping an embolic coil when the jaw member is closed.

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