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31. 发明授权

US10396807B1 Multi-ring coupled ring oscillator with improved phase noise 有权
公开(公告)号：US10396807B1
公开(公告)日：2019-08-27
申请号：US15819124
申请日：2017-11-21
申请人： Auburn University
发明人： Fa Dai , Ruixin Wang
IPC分类号： H03K3/013 , H03K3/03 , H03L7/099 , H03L7/07
摘要： The disclosure of the present application presents a multiple-ring coupled ring oscillator design that employs multiple-ring coupling to achieve improved phase noise by minimizing noise injection from tail current and adjacent rings, while providing additional output phases for multiphase signal generation. In one non-limiting exemplary prototype embodiment, a 1.5 GHz triple-ring coupled ring oscillator achieved measured phase noise of −110.5 dBc/Hz at 1 MHz offset, demonstrating phase noise reduction of 7 dB compared with its single-ring oscillator counterpart. The MROs couple multiple rings with proper phase shifting to achieve improved phase noise. Common source coupling benefits from tail current noise reduction, and introducing phase delays in the coupling paths minimizes noise coupling from the adjacent cores. The overall effect leads to improved phase noise performance as demonstrated in quadrature voltage controlled VCO designs. The concept is applied to ring oscillator designs and, as stated previously, demonstrates a triple-ring coupled ring oscillator with phase noise improvement. The design of the present application also triples the number of output phases compared to its single ring oscillator counterpart. The application of injection-locked PLL by using proposed multiple ring coupled ring oscillator achieves the same low phase noise as traditional IL-PLL does while lowering the reference spur at auxiliary ring's output. In another non-limiting exemplary embodiment, the proposed IL-PLL consumes 13.5 mW of power, while achieving in-band phase noise of −120.97 dBc/Hz at 1 MHz offset at 1.1 GHz output frequency.

32. 发明授权

US10329593B2 Efficient process for producing saccharides and ethanol from a biomass feedstock 有权
公开(公告)号：US10329593B2
公开(公告)日：2019-06-25
申请号：US15444780
申请日：2017-02-28
申请人： AUBURN UNIVERSITY
发明人： Benedict C. Okeke , Ananda K. Nanjundaswamy
IPC分类号： C12P19/14 , C12P19/02 , C12P7/14 , C12R1/885 , C12N9/24 , C12P7/10 , A23K20/10 , A01N63/04 , B09C1/10 , C12N9/42
摘要： Described herein is a process for producing saccharides and ethanol from biomass feedstock that includes (a) producing an enzyme composition by culturing a fungal strain(s) in the presence of a lignocellulosic medium, (b) using the enzyme composition to saccharify the biomass feedstock, and (c) fermenting the saccharified biomass feedstock to produce ethanol. The process is scalable and, in certain aspects, is capable of being deployed on farms, thereby allowing local production of saccharides and ethanol and resulting in a reduction of energy and other costs for farm operators. Optional steps to improve the biomass-to-fuel conversion efficiency are also contemplated, as are uses for byproducts of the process described herein.

33. 发明申请

US20190046634A1 RECOMBINANT SPIKE ECTODOMAIN PROTEINS, COMPOSITIONS, VECTORS, KITS, AND METHODS FOR IMMUNIZING AGAINST AVIAN INFECTIOUS BRONCHITIS VIRUS 审中-公开
公开(公告)号：US20190046634A1
公开(公告)日：2019-02-14
申请号：US16059803
申请日：2018-08-09
申请人： Auburn University
发明人： Vicky L. van Santen , Haroldo E. Toro
IPC分类号： A61K39/215 , A61P31/14 , C07K14/165
CPC分类号： A61K39/215 , A61K39/12 , A61K2039/552 , A61P31/14 , C07K14/005 , C07K14/165 , C12N2770/20022 , C12N2770/20034
摘要： Disclosed are recombinant spike ectodomain proteins, compositions, vectors, kits, and methods for inducing an immune response against avian infectious bronchitis virus (IBV). In particular, the recombinant proteins, compositions, vectors, kits, and methods relate to, include, and/or utilize a soluble, multimerized form of the (IBV) spike (S) protein ectodomain. The recombinant proteins, compositions, vectors, kits, and methods may be utilized to immunize poultry against disease associated with IBV infection or to protect poultry from IBV infection.

34. 发明授权

US10092639B2 Adaptation of attenuated infectious bronchitis virus (IBV) to embryonic kidney cells and vaccine thereby produced 有权
公开(公告)号：US10092639B2
公开(公告)日：2018-10-09
申请号：US15703640
申请日：2017-09-13
申请人： Auburn University
发明人： Haroldo E. Toro
IPC分类号： A61K39/215 , C12N7/00 , C07K14/165 , A61K39/12 , A61K39/00
摘要： Disclosed are methods for preparing a vaccine against infection by infectious bronchitis virus (IBV). The methods typically include passing a heterogeneous attenuated population of IBV in chicken embryonic kidney cells, and optionally may include further passaging the heterogeneous attenuated population of IBV in embryonated chicken eggs (ECE) in order to obtain passaged attenuated population of IBV. Also disclosed are passaged attenuated populations of IBV in which the populations display a desired degree of homogeneity. Also disclosed are vaccines comprising the passaged attenuated populations of IBV and methods of vaccination comprising administering the disclosed vaccines.

35. 发明授权

US09952297B2 Parallel plate transmission line for broadband nuclear magnetic resonance imaging 有权
公开(公告)号：US09952297B2
公开(公告)日：2018-04-24
申请号：US14706143
申请日：2015-05-07
申请人： AUBURN UNIVERSITY
发明人： Shumin Wang
IPC分类号： G01V3/00 , G01R33/345 , G01R33/34 , G01R33/36 , G01R33/48
CPC分类号： G01R33/345 , G01R33/34092 , G01R33/3635 , G01R33/3657 , G01R33/3678 , G01R33/4802
摘要： A parallel plate waveguide forms a volume coil used for magnetic resonance imaging and spectroscopy. The waveguide includes a first conductor arranged on a first side of the waveguide and a second conductor arranged on a second side of the waveguide. Excitation of the first conductor and the second conductor creates a transverse electromagnetic field between the first conductor and the second conductor which causes a target within the volume coil to emit radio frequency signals used for producing an image of the target.

36. 发明申请

US20180007866A1 Dynamic Canine Tracking Method for Hazardous and Illicit Substances 审中-公开
公开(公告)号：US20180007866A1
公开(公告)日：2018-01-11
申请号：US15701077
申请日：2017-09-11
申请人： Auburn University
发明人： John Pearce , L. Paul Waggoner , Jeanne S. Brock , Timothy Baird , David A. Baffa , Daniel McAfee , Robert E. Leonard
IPC分类号： A01K15/02 , F41H11/132 , A01K15/00 , A01K27/00 , G01N33/00 , F41H13/00
CPC分类号： A01K15/02 , A01K15/00 , A01K27/003 , F41H11/132 , F41H13/00 , G01N33/0001
摘要： Vapor wake detection is a highly advantageous method and system for detecting explosives and other illicit substances. With vapor wake detection, a canine and a handler are used; however, unlike other detection schemes, the canine leads the handler. After the handler positions the canine in a desired location, the canine detects scents in the air that come to the canine. When the canine detects a trained scent, the canine leads the handler to or follows behind the carrier of the item with the scent. Once the carrier is identified by the handler, the proper personnel are contacted. To implement vapor wake detection effectively, specific rigorous training is utilized.

37. 发明申请

US20170324555A1 SYSTEM AND METHOD FOR PREEMPTIVE SELF-HEALING SECURITY 审中-公开
公开(公告)号：US20170324555A1
公开(公告)日：2017-11-09
申请号：US15587946
申请日：2017-05-05
申请人： Auburn University
发明人： Chwan-Hwa Wu , J. David Irwin , Daoqi Hou
IPC分类号： H04L9/14 , H04L9/08 , H04L29/06
CPC分类号： H04L9/0819 , G06F21/54 , H04L9/0637 , H04L9/0869 , H04L9/0891 , H04L9/0894 , H04L9/3242 , H04L63/0428 , H04L63/1416 , H04L63/1483 , H04L2209/80
摘要： The present system and method allow for preemptive, self-healing computer security. The system includes a user device processor and a PSS server processor. The two processors perform an initial Data Structure & Key Mutation (DSKM) method and an interval DSKM method at a given interval to protect secret information and prevent its exposure by attackers. When a user requests a site or service that is an attractive target for attackers, such as a bank site or monetary transfer service, the processors perform a Man in the Browser attack prevention method. When a packet is received or generated, the processors perform a Deep Protocol and Stateful Inspection and Prevention method to prevent receipt of malicious packets or the loss of sensitive information. Various forensics modules allow accurate forensic examination of the type, scope, and method of attack, as well as real-time protection of cloud-based services.

38. 发明授权

US09756854B2 Treated biodiesel glycerin 有权
公开(公告)号：US09756854B2
公开(公告)日：2017-09-12
申请号：US15271550
申请日：2016-09-21
申请人： Auburn University
发明人： Rodrigo Rodriguez-Kabana , Robert H. Walker
IPC分类号： A01N31/02 , C05G3/02 , C05C9/00
CPC分类号： A01N35/02 , A01N31/02 , C05B17/00 , C05C9/00 , C05G3/02 , Y02E50/343 , Y02W30/47 , A01N37/46 , A01N47/28 , A01N63/02
摘要： Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling.

39. 发明授权

US09746443B2 In-situ pathogen detection using magnetoelastic sensors 有权
公开(公告)号：US09746443B2
公开(公告)日：2017-08-29
申请号：US14064308
申请日：2013-10-28
申请人： Bryan A. Chin , Zhongyang Cheng , Suiqiong Li , Mi-Kyung Park , Shin Horikawa , Yating Chai , Kanchana Weerakoon , Stevie R. Best , Martin E. Baltazar-Lopez , Howard C. Wikle
发明人： Bryan A. Chin , Zhongyang Cheng , Suiqiong Li , Mi-Kyung Park , Shin Horikawa , Yating Chai , Kanchana Weerakoon , Stevie R. Best , Martin E. Baltazar-Lopez , Howard C. Wikle
IPC分类号： G01N27/72 , G01N27/74 , G01N33/543
CPC分类号： G01N27/72 , G01N27/745 , G01N33/54373
摘要： In at least one illustrative embodiment, a method for in-situ pathogen detection may comprise distributing one or more magnetoelastic measurement sensors on a surface of a test object, wherein each of the one or more magnetoelastic measurement sensors includes a biorecognition element configured to bind with a pathogen to cause a shift in a characteristic frequency of the associated measurement sensor; applying a varying magnetic field, using a test coil, to the one or more magnetoelastic measurement sensors distributed on the surface of the test object, wherein the test object is positioned outside of an inner volume defined by the test coil; detecting a frequency response of the one or more magnetoelastic measurement sensors using the test coil, while applying the varying magnetic field; and determining whether the pathogen is present based on the detected frequency response of the one or more magnetoelastic measurement sensors.

40. 发明授权

US09724398B2 Combination of protein forms for hornfly vaccination 有权
公开(公告)号：US09724398B2
公开(公告)日：2017-08-08
申请号：US14752081
申请日：2015-06-26
申请人： Auburn University
发明人： Mary S. Cupp , Eddie W. Cupp , Christine Navarre , Dunhua Zhang , Latora W. Todd Jackson , Eugene Blair
IPC分类号： A61K39/00
CPC分类号： A61K39/0003 , A61K2039/552
摘要： Thrombostasin is an anti-clotting protein found in saliva of Haematobia irritans. Disclosed herein are studies testing blood uptake of horn flies feeding on cattle which confirm the association of ts genotype with blood uptake of horn flies. Blood uptake volumes of homozygous ts10 horn flies were lower than those of other ts genotypes when fed on control cattle. Cattle vaccinated with recombinant protein isoforms rTS9 or rTB8 resisted horn fly feeding by yielding lower blood volumes compared to flies feeding on control cattle. The impact of vaccination varied by ts genotype of flies. Cattle vaccinated with isoforms rTS9 resisted flies of ts2, ts9, and tb8 genotype. Vaccination with isoforms rTB8 produced resistance to ts8, ts9 and tb8 genotype flies. Horn flies of genotype ts10 were not affected with either TS isoforms and fed well on rTS9 and rTB9 vaccinated as on control-vaccinated cattle.

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