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    • 21. 发明申请
    • Spray Delivery Device
    • 喷雾装置
    • US20150232260A1
    • 2015-08-20
    • US14619127
    • 2015-02-11
    • Mission Pharmacal Company
    • Thomas DannRenee NelsonBrian WagnerMary Walter
    • B65D83/14A61K9/00A61K47/06B65D83/48A61K47/24A61K47/26B65D83/32A61K9/12A61K33/30
    • B65D83/752A61K9/0014A61K9/124A61K33/30A61K47/06A61K47/24A61K47/26B05B7/0483B65D83/206B65D83/32B65D83/48
    • A spray delivery system including a sprayable active agent composition housed within a container is provided that can be used in the treatment of various skin conditions. The composition includes a hydrofluoro-based propellant, a carrier fluid, and active agent particles, and has a viscosity ranging from about 500 centipoise to about 10,000 centipoise. The container includes a dip tube; a valve assembly that includes a valve body, a stem comprising a stem orifice, and a vapor tap; and an actuator. The dip tube is coupled to the actuator by the valve assembly, and the actuator is depressed to dispense the emulsion. By selectively controlling the components and viscosity of the composition and the dimensions of the container components, the active agent particles resist settling so a substantially homogeneous distribution of the particles is maintained. Thus, the composition can be evenly dispensed from the container as a fine mist without clogging.
    • 提供一种包含容纳在容器内的可喷雾活性剂组合物的喷雾递送系统,其可用于治疗各种皮肤状况。 组合物包括氢氟基推进剂,载体流体和活性剂颗粒,并且具有约500厘泊至约10,000厘泊的粘度。 容器包括汲取管; 阀组件,其包括阀体,包括阀杆孔的阀杆和蒸汽龙头; 和致动器。 汲取管通过阀组件联接到致动器,并且致动器被压下以分配乳液。 通过选择性地控制组合物的组分和粘度以及容器组分的尺寸,活性剂颗粒抵抗沉降,从而保持颗粒的基本上均匀的分布。 因此,可以将组合物从容器中均匀地分配为细雾而不堵塞。
    • 26. 发明授权
    • Dispensing system from a container under pressure
    • 在压力下从容器中分配系统
    • US5439148A
    • 1995-08-08
    • US98323
    • 1993-10-14
    • Johannes W. J. Driessen
    • Johannes W. J. Driessen
    • B65D83/44B65D20060101B65D83/16B65D83/32B65D83/00
    • B65D83/20
    • In an aerosol provided with a container for a medium under pressure, and with a spray nozzle which is connected to a medium supply device of the container, and with which the medium can be sprayed after the opening of a valve provided between container and supply device, the spray nozzle and the supply device are provided with fixing devices for irreversibly fixing the spray nozzle on the supply device. For this purpose, the supply device and the spray nozzle can bear barbed fixing devices, in such a way that the spray nozzle can be fitted on the supply device by sliding towards it, but is blocked in the oppposite direction. The parts of the spray nozzle and/or of the supply device determining the flow connection can have a weakened part, which weakened part is broken when the spray nozzle is removed from the supply device, in such a way that the flow connection is damaged.
    • PCT No.PCT / NL92 / 00026 Sec。 371日期:1993年10月14日 102(e)日期1993年10月14日PCT提交1992年2月5日PCT公布。 公开号WO92 / 13780 日期为1992年8月20日。在具有用于压力介质的容器的气溶胶中,并且具有连接到容器的介质供应装置的喷嘴,并且可以在打开介质之后喷射介质 设置在容器和供应装置之间的阀,喷嘴和供应装置设置有用于将喷嘴不可逆地固定在供应装置上的固定装置。 为此,供应装置和喷嘴可以承受带刺的固定装置,使得喷嘴可以通过朝向供应装置滑动而被安装在供应装置上,但是在相对的方向上被阻挡。 确定流动连接的喷嘴和/或供应装置的部件可以具有弱化部分,当喷嘴从供给装置移除时,削弱部分被破坏,使得流动连接被损坏。