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21. 发明授权

US08618800B2 Magnetic resonance imaging apparatus, and breath-holding imaging method 有权
标题翻译：磁共振成像装置和呼吸保持成像方法
公开(公告)号：US08618800B2
公开(公告)日：2013-12-31
申请号：US13122309
申请日：2009-10-02
申请人： Yasuhiro Kamada
发明人： Yasuhiro Kamada
IPC分类号： G01V3/00
CPC分类号： A61B5/055 , G01R33/5602 , G01R33/5607 , G01R33/5613 , G01R33/56509
摘要： In order to make it possible to set the optimal breath-holding imaging conditions according to the subject without extension of an imaging time or the sacrifice of image quality, one scan is divided into one or more breath-holding measurements and free-breathing measurements on the basis of the imaging conditions of a breath-holding measurement, which are input and set according to the subject, and a region of the k space measured in the breath-holding measurement is controlled. Preferably, in the breath-holding measurement, low-frequency data of the k space is measured. Moreover, preferably, imaging conditions of the breath-holding measurement include the number of times of breath holding or a breath-holding time, and the operator can set any of these values.
摘要翻译：为了使得可以根据被摄体设置最佳的呼吸保持成像条件而不延长成像时间或牺牲图像质量，一次扫描被分成一次或多次呼吸测量和自由呼吸测量控制根据被摄体输入和设定的呼吸保持测量的成像条件的基础以及在保持测量中测量的k空间的区域。优选地，在呼吸保持测量中，测量k空间的低频数据。此外，优选地，呼吸保持测量的成像条件包括呼吸次数或呼吸保持时间，并且操作者可以设置这些值中的任何一个。

22. 发明申请

US20130257429A1 Method for Non-Contrast Enhanced Magnetic Resonance Angiography 有权
标题翻译：非对比增强磁共振血管造影术的方法
公开(公告)号：US20130257429A1
公开(公告)日：2013-10-03
申请号：US13906877
申请日：2013-05-31
申请人： Robert R. Edelman
发明人： Robert R. Edelman
IPC分类号： G01R33/563
CPC分类号： G01R33/5635 , A61B5/055 , G01R33/5607 , G01R33/5613 , G01R33/56509 , G01R33/5673
摘要： A method for non-contrast enhanced magnetic resonance angiography (“MRA”) that has a short scan time and is insensitive to patient motion is provided. More particularly, the method provides significant arterial conspicuity and substantial venous signal suppression. A two-dimensional single shot acquisition is employed and timed to occur a specific time period after the occurrence of an R-wave in a contemporaneously recorded electrocardiogram. In this manner, k-space data is acquired that is substantially insensitive to variations in arterial flow velocity, or heart rate, and that further substantially suppresses unwanted venous signal in a prescribed imaging slice. Alternatively, a two-dimensional multi-shot acquisition is employed to acquire k-space data using an echo train length that is sufficiently short so as to suppress flow-related artifacts, and such that cardiac gating is not required.
摘要翻译：提供了具有短扫描时间并且对患者运动不敏感的非对比度增强磁共振血管造影（“MRA”）的方法。更具体地，该方法提供显着的动脉显着性和显着的静脉信号抑制。采用二维单次采集并定时发生在同时记录的心电图中出现R波之后的特定时间段。以这种方式，获得对动脉血流速度或心率的变化基本上不敏感的k空间数据，并且进一步基本上抑制规定的成像切片中的不希望的静脉信号。或者，使用二维多次采集来采用足够短的回波串长度来获取k空间数据，以便抑制与流量有关的伪影，并且不需要心脏选通。

23. 发明授权

US08483798B2 System and method for metabolic MR imaging of a hyperpolarized agent 有权
标题翻译：超极化剂代谢MR成像的系统和方法
公开(公告)号：US08483798B2
公开(公告)日：2013-07-09
申请号：US11623277
申请日：2007-01-15
申请人： J. Stefan Petersson , Sven Mansson , Klaus Scheffler
发明人： J. Stefan Petersson , Sven Mansson , Klaus Scheffler
IPC分类号： A61B5/05
CPC分类号： G01R33/54 , G01R33/4828 , G01R33/485 , G01R33/5601 , G01R33/5613 , G01R33/5614
摘要： A system and method for metabolic MR imaging of a hyperpolarized agent includes exciting a single metabolic species of a hyperpolarized agent injected into a subject of interest. MR signals are acquired from the excited single metabolic species and an image is reconstructed from the acquired MR signals.
摘要翻译：用于超极化剂的代谢MR成像的系统和方法包括激发注射到感兴趣的受试者中的超极化剂的单一代谢物质。从兴奋的单一代谢物种获得MR信号，并从所获取的MR信号重建图像。

24. 发明授权

US08188735B2 Resolution enhanced T1-insensitive steady state imaging (RE-TOSSI) 有权
标题翻译：分辨率增强T1不敏感稳态成像（RE-TOSSI）
公开(公告)号：US08188735B2
公开(公告)日：2012-05-29
申请号：US12290343
申请日：2008-10-29
申请人： Jamal J. Derakhshan , Mark A. Griswold , Jeffrey L. Duerk
发明人： Jamal J. Derakhshan , Mark A. Griswold , Jeffrey L. Duerk
IPC分类号： G01V3/00
CPC分类号： G01R33/5613 , G01R33/5602 , G01R33/5614
摘要： Systems, methods, and other embodiments associated with RE-TOSSI are described. One system embodiment includes an MRI apparatus configured to produce a RE-TOSSI pulse sequence and to acquire T2-weighted images in response to the RE-TOSSI pulse sequence. An example RE-TOSSI pulse sequence includes a TOSSI portion and a non-inverting, non-TOSSI portion.
摘要翻译：描述了与RE-TOSSI相关联的系统，方法和其它实施例。一个系统实施例包括被配置为产生RE-TOSSI脉冲序列并响应于RE-TOSSI脉冲序列获取T2加权图像的MRI设备。示例性RE-TOSSI脉冲序列包括TOSSI部分和非反相非TOSSI部分。

25. 发明申请

US20120074937A1 Increasing spoil efficiency 有权
标题翻译：增加弃渣效率
公开(公告)号：US20120074937A1
公开(公告)日：2012-03-29
申请号：US12929597
申请日：2011-02-03
申请人： Jochen Leupold
发明人： Jochen Leupold
IPC分类号： G01R33/54
CPC分类号： G01R33/5613
摘要： A method for operating a nuclear magnetic resonance imaging device, wherein a continuous sequence of radio-frequency (=RF) pulses are radiated onto a sample, Ψ being the constant phase value for all magnetization vectors, and all magnetization vectors undergo a phase progression Fn=nΨ during the n-th sequence interval, wherein P is the number of RF pulses after which the phase angle of the magnetization vectors is repeated, wherein the total gradient moment in one or more directions in space having a value greater than 0, and consecutive pulses exhibit a constant repetition time TR, wherein, after radiation of one RF pulse, one k-space row is acquired. The method is characterized in that any one- or multi-dimensional arrangement of k-space rows is repeated identically N times, and signals from identical k-space rows are averaged or added. The method increases the efficiency of the gradient spoiling and thus the efficiency of artifact suppression.
摘要翻译：一种用于操作核磁共振成像装置的方法，其中将射频（= RF）脉冲的连续序列辐射到样本上，Ψ是所有磁化矢量的恒定相位值，并且所有磁化矢量经历相位进行Fn =nΨ，其中P是RF脉冲的数量，在此之后重复磁化矢量的相位角，其中空间中一个或多个方向上的总梯度矩大于0，以及连续的脉冲呈现恒定的重复时间TR，其中在一个RF脉冲的辐射之后，获取一个k空间行。该方法的特征在于，k空间行的任何一维或多维排列重复相同N次，并且来自相同k空间行的信号被平均或相加。该方法提高了梯度扰动的效率，从而提高了伪影抑制效率。

26. 发明授权

US07825662B2 MRI apparatus and control method of steady-state free precession (SSFP) with phase cycling, combining low and high frequency images multiplied by a scaling factor 有权
标题翻译：具有相位循环的稳态自由进动（SSFP）的MRI装置和控制方法，将低频和高频图像乘以比例因子
公开(公告)号：US07825662B2
公开(公告)日：2010-11-02
申请号：US12062388
申请日：2008-04-03
申请人： Yongchuan Lai
发明人： Yongchuan Lai
IPC分类号： G01V3/00
CPC分类号： G01R33/5613 , G01R33/565 , G01R33/56554
摘要： An MRI apparatus includes an imaging device that performs MR imaging in an SSFP pulse sequence in which a phase cycling method produces RF excitation, and a control device that causes the imaging device; to collect data regarding a plurality of frequency regions in k-space in the SSFP pulse sequence in a first phase series; to collect data regarding low frequency regions in k-space in the SSFP pulse sequence in a plurality of remaining phase series; to generate frequency data based on the collected data, substitute data into high and low frequency regions of the frequency data, reconstruct low space frequency images based on the low frequency regions to which substitute data is added, reconstruct high space frequency images based on the high frequency regions to which substitute data have been added and combine the low space frequency images and the high space frequency images multiplied by a scaling factor.
摘要翻译： MRI装置包括在相位循环方法产生RF激励的SSFP脉冲序列中执行MR成像的成像装置和使成像装置进行的控制装置; 以第一相序列收集关于SSFP脉冲序列中的k空间中的多个频率区域的数据; 收集关于SSFP脉冲序列中的k空间中的低频区域的数据的多个剩余相位序列; 基于收集的数据生成频率数据，将数据代入频率数据的高频和低频区域，基于添加了替代数据的低频区域重建低空间频率图像，基于高频重构高空间图像已经添加了替代数据的频率区域，并且组合了低空间频率图像和高空间频率图像乘以比例因子。

27. 发明申请

US20100160767A1 METHOD FOR CONTRAST-AGENT-FREE ANGIOGRAPHIC IMAGING IN MAGNETIC RESONANCE TOMOGRAPHY 有权
标题翻译：磁共振成像中对比无代谢成像的方法
公开(公告)号：US20100160767A1
公开(公告)日：2010-06-24
申请号：US12645858
申请日：2009-12-23
申请人： Michael Deimling
发明人： Michael Deimling
IPC分类号： A61B5/055
CPC分类号： G01R33/5635 , G01R33/5613 , G01R33/5614
摘要： A method for contrast-agent-free non-triggered angiographic imaging in magnetic resonance tomography that includes the steps of (S1) 2D or 3D measurement of a bodily region having a flow of blood, using a flow-insensitive SSFP sequence, (S2) measurement of the same bodily region using a flow-sensitive SSFP sequence, (S3) registration of the measurement results obtained in steps S1 and S2 to one another, (S4) unweighted or self-weighted subtraction of the registered measurement result obtained in step S2 from the registered measurement result obtained in step S1, (S5) execution of a 2D or 3D image correction of the image obtained in step S4 by removing image distortions caused by gradient field inhomogeneities and/or magnetic basic field inhomogeneities, and (S6) representation of the angiogram obtained in step S5 in the form of an MIP or segmented 2D or 3D vessel tree representation.
摘要翻译：一种在磁共振断层摄影中不造成造影剂的非触发血管造影成像的方法，其包括以下步骤：（S1）使用不流动感的SSFP序列的具有血流的身体区域的2D或3D测量;（S2）使用流敏SSFP序列测量相同的身体区域，（S3）将步骤S1和S2中获得的测量结果相互注册，（S4）在步骤S2中获得的登记的测量结果的未加权或自加权相减从步骤S1中获得的注册测量结果，（S5）通过消除由梯度场不均匀性和/或磁性基本场不均匀性引起的图像失真来执行在步骤S4中获得的图像的2D或3D图像校正，以及（S6）表示以MIP或分段的2D或3D血管树表示的形式在步骤S5中获得的血管造影。

28. 发明申请

US20100102816A1 EDDY-CURRENT ARTIFACT REDUCTION IN BALANCED STEADY-STATE FREE PRECESSION MAGNETIC RESONANCE IMAGING 有权
标题翻译：平衡状态下的EDDY-CURRENT ARTIFACT减少自由前导磁共振成像
公开(公告)号：US20100102816A1
公开(公告)日：2010-04-29
申请号：US12582409
申请日：2009-10-20
申请人： Jon-Fredrik Nielsen , Krishna S. Nayak
发明人： Jon-Fredrik Nielsen , Krishna S. Nayak
IPC分类号： G01R33/48
CPC分类号： G01R33/5613 , G01R33/5614 , G01R33/56316 , G01R33/56518
摘要： Magnetic resonance imaging techniques are described that utilize bSSFP sequences in which two or more gradient waveforms are interleaved in a “groupwise” fashion, i.e., each waveform is executed consecutively two or more times before switching to the other waveform, where “N” counts the number of times each waveform is executed consecutively. As a result, embodiments of the present disclosure can mitigate steady-state signal distortions or artifacts in interleaved balanced steady-state free precession (bSSFP) caused by slightly unbalanced eddy-current fields. Related MRI systems are also described.
摘要翻译：描述了使用其中两个或多个梯度波形以“分组”方式交错的bSSFP序列的磁共振成像技术，即，在切换到另一个波形之前，每个波形连续执行两次或更多次，其中“N”计数连续执行每个波形的次数。结果，本公开的实施例可以减轻由轻微不平衡的涡流场引起的交错平衡稳态自由进动（bSSFP）中的稳态信号失真或伪影。还描述了相关的MRI系统。

29. 发明申请

US20100052675A1 System for Image Acquisition With Fast Magnetic Resonance Gradient Echo Sequences 有权
标题翻译：用快速磁共振梯度回波序列进行图像采集的系统
公开(公告)号：US20100052675A1
公开(公告)日：2010-03-04
申请号：US12504789
申请日：2009-07-17
申请人： Agus Priatna , Stephan Kannengiesser
发明人： Agus Priatna , Stephan Kannengiesser
IPC分类号： G01R33/48
CPC分类号： G01R33/561 , G01R33/5613 , G01R33/56509
摘要： A system uses a three-dimensional spoiled gradient recalled echo sequence for fat suppression with reduced total acquisition time suitable for acquiring image data under breath-hold conditions using a reversed asymmetry during data acquisition on an opposed phase echo. A system reduces RF pulse repetition time in an MR imaging pulse sequence in an MR imaging device. The system includes an RF pulse generator for generating an RF excitation pulse sequence having a pulse repetition interval. A read-out gradient magnetic field generator generates an asymmetric read-out gradient magnetic field having a readout gradient mid-point occurring prior to an RF echo pulse peak. The RF echo pulse peak is received in response to a generated RF excitation pulse.
摘要翻译：系统使用三维损坏梯度回归序列进行脂肪抑制，减少总采集时间，适用于在相对相位回波数据采集期间使用逆向不对称，在呼吸保持条件下获取图像数据。一种系统降低MR成像装置中的MR成像脉冲序列中的RF脉冲重复时间。该系统包括用于产生具有脉冲重复间隔的RF激励脉冲序列的RF脉冲发生器。读出梯度磁场发生器产生具有在RF回波脉冲峰值之前出现的读出梯度中点的非对称读出梯度磁场。响应于产生的RF激励脉冲接收RF回波脉冲峰值。

30. 发明授权

US07646198B2 Methods for fat signal suppression in magnetic resonance imaging 有权
标题翻译：磁共振成像中脂肪信号抑制的方法
公开(公告)号：US07646198B2
公开(公告)日：2010-01-12
申请号：US12044442
申请日：2008-03-07
申请人： Candice A. Bookwalter , Jeffrey L. Sunshine , Jeffrey L. Duerk
发明人： Candice A. Bookwalter , Jeffrey L. Sunshine , Jeffrey L. Duerk
IPC分类号： G01V3/00
CPC分类号： G01R33/5614 , G01R33/4828 , G01R33/5607 , G01R33/5613
摘要： The present invention is directed to methods for chemical species signal suppression in magnetic resonance imaging procedures, wherein Dixon techniques are enhanced by continuously sampling techniques. In the invention, k-space data is acquired during the entire period of read gradient associated with a gradient echo pulse acquisition scheme. The invention utilizes a total sampling time (TST) acquisition during the entire read gradient, using three echoes of a TST data set to achieve chemical species separation in both homogenous fields as well as areas of field inhomogeneity. As an example, a continuously sampled rectilinearly FLASH pulse sequence is modified such that the time between echoes was configured to be 2.2 milliseconds, with TE selected to allow 180° phase variation in the fat magnetization between each of the three TE's (TE1, TE2, and TE3). Data collected during the dephase and rephase gradient lobes are defined as a first Dixon acquisition, with data collected by the read gradient lobe being defined as a second Dixon acquisition. Two point Dixon reconstruction techniques are used to form images for each chemical species, such as for generating water and fat images of the scanned object region. Other corrections, such as off-resonance correction may be applied on the image data.
摘要翻译：本发明涉及磁共振成像过程中化学物质信号抑制的方法，其中通过连续采样技术增强狄克逊技术。在本发明中，在与梯度回波脉冲获取方案相关联的读取梯度的整个周期期间获取k空间数据。本发明利用在整个读取梯度期间的总采样时间（TST）采集，使用TST数据集的三个回波来实现均匀场中的化学物质分离以及场不均匀性的区域。作为示例，修改连续采样的直线式FLASH脉冲序列，使得回波之间的时间被配置为2.2毫秒，其中TE被选择为允许三个TE（TE1，TE2，TE2）中的每一个之间的脂肪磁化的180°相位变化，和TE3）。在去除和重新形成梯度波瓣期间收集的数据被定义为第一次Dixon采集，由读取梯度波段收集的数据被定义为第二次Dixon采集。两点Dixon重建技术用于形成每个化学物种的图像，例如用于产生被扫描物体区域的水和脂肪图像。可以对图像数据应用诸如非共振校正的其他校正。

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