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21. 发明申请

US20110180701A1 NANOPARTICLE ELECTROSTATIC TRAP 有权
标题翻译：纳米材料静电捕捉
公开(公告)号：US20110180701A1
公开(公告)日：2011-07-28
申请号：US13011413
申请日：2011-01-21
申请人： Jorg C. Woehl , Christine A. Carlson
发明人： Jorg C. Woehl , Christine A. Carlson
IPC分类号： B01D59/44 , B05D5/12
CPC分类号： B82B3/0076 , B03C5/00 , B03C2201/26
摘要： A method of trapping a charged particle. The method includes providing a planar substrate having a conductive surface thereon, the conductive surface having at least one non-conductive region. The method also includes applying a solution to the conductive surface, the solution comprising at least one charged particle. The method further includes applying a voltage of a threshold level to the conductive surface. The method also includes, in response to the voltage, generating an electrostatic field in the solution adjacent to a boundary between the conductive surface and the non-conductive region. The method also includes setting the threshold level of voltage to result in a strength of the electrostatic field sufficient to prevent the particle from crossing the electrostatic field.
摘要翻译：捕获带电粒子的方法。该方法包括提供其上具有导电表面的平面基板，该导电表面具有至少一个非导电区域。该方法还包括将溶液施加到导电表面，该溶液包含至少一个带电粒子。该方法还包括向导电表面施加阈值电平的电压。该方法还包括响应于电压，在与导电表面和非导电区域之间的边界相邻的溶液中产生静电场。该方法还包括设置电压的阈值电平以产生足以防止颗粒穿过静电场的静电场的强度。

22. 发明申请

US20100261878A1 SEQUENCES FOR FK228 BIOSYNTHESIS AND METHODS OF SYNTHESIZING FK228 AND FK228 ANALOGS 失效
标题翻译： FK228和FK228类似物的合成序列及其合成方法
公开(公告)号：US20100261878A1
公开(公告)日：2010-10-14
申请号：US12526202
申请日：2008-02-08
申请人： Yi-Qiang Cheng
发明人： Yi-Qiang Cheng
IPC分类号： C12P21/02 , C07K5/10
CPC分类号： C07K11/02 , C12N15/52 , C12P17/187
摘要： Polynucleotides encoding the polypeptides involved in biosynthesis of FK 228 and those involved in synthesis of a novel FK228 analog, thailandepsin are disclosed herein. Also provided are methods of making FK228, thailandepsin and analogs of these molecules and methods of using these FK228 analogs. Chromobacterium and Burkholderia gene inactivation mutants are provided. Methods of forming a disulfide bond in a chemical are also disclosed.
摘要翻译：编码参与FK 228的生物合成的多肽的多核苷酸以及参与合成新型FK228类似物泰乐蛋白的那些。还提供了制备FK228，泰国蛋白和这些分子的类似物的方法以及使用这些FK228类似物的方法。提供了色杆菌和伯克霍尔德氏菌基因灭活突变体。还公开了在化学品中形成二硫键的方法。

23. 发明申请

US20080062862A1 SYSTEM AND METHOD FOR SCHEDULING ROUTING TABLE CALCULATION IN LINK STATE ROUTING PROTOCOLS 失效
标题翻译：在链路状态路由协议中调度路由表计算的系统和方法
公开(公告)号：US20080062862A1
公开(公告)日：2008-03-13
申请号：US11852025
申请日：2007-09-07
申请人： Mukul Goyal , Seyed H. Hosseini
发明人： Mukul Goyal , Seyed H. Hosseini
IPC分类号： H04L12/28
CPC分类号： H04L45/123 , H04L45/00 , H04L45/02 , H04L45/028 , H04L45/26 , H04L69/40
摘要： A method, and a system, called link state advertisement (“LSA“) correlation, for scheduling routing table updates following a topology change. LSA correlation correlates information in the LSAs to identify the topology change that led to their generation. A routing table update is performed when a topology change has been identified.
摘要翻译：称为链路状态通告（“LSA”）相关的方法和系统，用于在拓扑变化之后调度路由表更新。 LSA相关关联LSA中的信息，以识别导致其生成的拓扑变化。当确定拓扑变化时，执行路由表更新。

24. 发明授权

US12065658B2 Sterile mutant and two line breeding system 有权
公开(公告)号：US12065658B2
公开(公告)日：2024-08-20
申请号：US16959928
申请日：2019-01-03
申请人： UWM Research Foundation, Inc. , United States of America, As Represented by the Secretary of Agriculture
发明人： Dazhong Zhao , Zhanguo Xin
IPC分类号： C12N15/82
CPC分类号： C12N15/8289
摘要： Disclosed herein are nuclear male sterile sorghum mutants, three-component genetic constructs, and methods of using said mutants and genetic constructs, such as in a two-line male sterility system for hybrid breeding.

25. 发明授权

US12054491B2 Substituted benzo[f]imidazo[1,5-a][1,4]diazepines as GABA(a) receptor modulators 有权
公开(公告)号：US12054491B2
公开(公告)日：2024-08-06
申请号：US17886403
申请日：2022-08-11
申请人： UWM Research Foundation, Inc. , The Trustees of Columbia University in the City of New York
发明人： Alexander E. Arnold , Douglas C. Stafford , James M. Cook , Charles W. Emala , Gloria Forkuo , Rajwana Jahan , Revathi Kodali , Guanguan Li , Michael Rajesh Stephen
IPC分类号： C07D487/04 , A61P11/06 , C07D487/14
CPC分类号： C07D487/14 , A61P11/06 , C07D487/04
摘要： The present invention describes substituted benzo[f]imidazo[1,5-a][1,4]diazepines of the formula (I):

wherein R1, R2, R2′, R3, and X are as disclosed herein. These compounds target alpha-4 and alpha-5 GABAa receptors and are useful for the treatment of airway hyperresponsiveness and inflammation in asthma.

26. 发明授权

US11959875B2 Composition, electrode, and fabrication method for phosphate sensing 有权
公开(公告)号：US11959875B2
公开(公告)日：2024-04-16
申请号：US16631104
申请日：2018-08-10
申请人： UWM Research Foundation, Inc.
发明人： Woo-Jin Chang , Misong Ryu , Mohammad Rizwen Ur Rahman
IPC分类号： G01N27/333 , G01N27/30 , G01N27/48 , G01N33/18
CPC分类号： G01N27/333 , G01N27/307 , G01N27/308 , G01N27/48 , G01N33/182
摘要： Composition and electrode for phosphate sensing. In one embodiment, the composition includes a first component, a second component, and a third component. The first component is selected from a group consisting of cobalt oxide nanoparticles, tin (IV) chloride, diphenyl tin dichloride, and ammonium molybdate. The second component includes graphene oxide or reduced graphene oxide. The third component includes pyrrole or polypyrrole.

27. 发明公开

US20230285472A1 PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF FISH DISEASES CAUSED BY BACTERIA AND FUNGI 审中-公开
公开(公告)号：US20230285472A1
公开(公告)日：2023-09-14
申请号：US18120528
申请日：2023-03-13
申请人： T3 BIOSCIENCE, LLC , UWM RESEARCH FOUNDATION, INC.
发明人： Ching-Hong Yang , Jian Huang
IPC分类号： A61K35/74 , A61K31/05 , A61P31/04
CPC分类号： A61K35/74 , A61K31/05 , A61P31/04
摘要： The present invention relates to an antimicrobial composition and probiotics against bacterial and fungal pathogens of fish. In particular, the invention pertains to a novel strain of the bacterial species Pseudomonas chlororaphis subsp. aurantiaca 1214-CHY4 (ATCC accession number PTA-126941), the cells, cell broth, and novel metabolites produced from the bacterial strain that can inhibit the growth of a variety of fish pathogens.

28. 发明授权

US11590115B2 Pseudomonas strains and their metabolites to control fish diseases 有权
公开(公告)号：US11590115B2
公开(公告)日：2023-02-28
申请号：US17494068
申请日：2021-10-05
申请人： T3 BIOSCIENCE, LLC , UWM RESEARCH FOUNDATION, INC.
发明人： Ching-Hong Yang , Jian Huang
IPC分类号： A61K31/04 , A61K31/4412 , A61P31/04 , A61K35/74
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of fish pathogens. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to a compound having Formula (I):

29. 发明授权

US11427582B2 Ligands selective to alpha 6 subunit-containing GABAA receptors and their methods of use 有权
公开(公告)号：US11427582B2
公开(公告)日：2022-08-30
申请号：US17078739
申请日：2020-10-23
申请人： UWM Research Foundation, Inc.
发明人： James Cook , Daniel Knutson
IPC分类号： C07D471/04 , C07D471/14 , A61K31/4745 , C07D498/14 , C07D495/14 , C07D491/147 , A61P25/18 , A61P25/24 , A61P27/16 , A61P25/06
摘要： Provided herein are novel pyrazoloquinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.

30. 发明申请

US20220105080A1 PSEUDOMONAS STRAINS AND THEIR METABOLITES TO CONTROL FISH DISEASES 有权
公开(公告)号：US20220105080A1
公开(公告)日：2022-04-07
申请号：US17494068
申请日：2021-10-05
申请人： T3 BIOSCIENCE, LLC , UWM RESEARCH FOUNDATION, INC.
发明人： Ching-Hong Yang , Jian Huang
IPC分类号： A61K31/4412 , A61K35/74 , A61P31/04
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of fish pathogens. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to a compound having Formula (I):

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