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21. 发明申请

US20170014460A1 INHIBITION OF HYPOXIA-INDUCIBLE FACTOR ACTIVITY WITH CARICA PAPAYA EXTRACTS 有权
标题翻译：辣椒素提取物诱导的高磷诱导因子活性的抑制作用
公开(公告)号：US20170014460A1
公开(公告)日：2017-01-19
申请号：US15279999
申请日：2016-09-29
申请人： The Regents of the University of California , Universiti Putra Malaysia
发明人： Eric J. Stanbridge , Norazizah Shafee , Khatijah Yusoff
IPC分类号： A61K36/185
CPC分类号： A61K36/185 , A61K31/549 , A61K33/24 , A61K2236/00 , A61K2236/33
摘要： An extract of Carica papaya leaves obtained from a plant of age six months and younger from the date of germination of the seed is used as an inhibitor of HIF to effectively block hypoxia-inducible factor (HIF) function and methods of use thereof. More specifically it relates to the use of the Carica papaya plant extract to eliminate unwanted cells by inhibiting HIF in the prevention and treatment of hypoxia-related conditions and diseases such as inflammatory diseases, vascular diseases, cancer and infectious diseases. In a particular embodiment, a solid hypoxic tumor in a patient is treated by administering to the patient a therapeutically acceptable amount of an extract of Carica papaya leaves obtained from a plant of age six months and younger from the date of germination of the seed, preferably an alcohol extract such as a methanol extract, whereby to inhibit hypoxia-inducible factors in the tumor.
摘要翻译：使用从种子发芽之日起六个月以下的植物获得的番木瓜叶提取物作为HIF的抑制剂，以有效阻断缺氧诱导因子（HIF）的功能及其使用方法。更具体地说，它涉及番木瓜植物提取物通过抑制HIF来预防和治疗缺氧相关病症和诸如炎性疾病，血管疾病，癌症和感染性疾病的疾病来消除不需要的细胞的用途。在一个具体实施方案中，通过向患者施用治疗可接受量的从六月份的植物获得的番木瓜叶提取物并且从种子发芽之日起更年轻地治疗患者体内的固体缺氧性肿瘤醇提取物如甲醇提取物，从而抑制肿瘤中的缺氧诱导因子。

22. 发明授权

US09539399B2 Safety syringe 有权
标题翻译：安全注射器
公开(公告)号：US09539399B2
公开(公告)日：2017-01-10
申请号：US14130988
申请日：2012-07-11
申请人： Abd.Rahim Abu.Talib , Adi Azriff Basri , Siti Zuraifah Mohd.Zabidi , Mohd Salleh Yahaya , Khairi Mat.Isa
发明人： Abd.Rahim Abu.Talib , Adi Azriff Basri , Siti Zuraifah Mohd.Zabidi , Mohd Salleh Yahaya , Khairi Mat.Isa
IPC分类号： A61M5/50 , A61M5/32 , A61M5/315
CPC分类号： A61M5/50 , A61M5/31511 , A61M5/31515 , A61M5/3205 , A61M2005/3279
摘要： The present invention relates to a safety syringe (100) having a hollow barrel (1), plunger (2) and a detachable needle support (4), characterized in that the safety syringe (100) includes; a) a piston gasket (3) interference fit with the plunger head (7) of the plunger (2); b) a plurality of bone structures (6) provided at the barrel head (1a) of the hollow barrel (1) to temporarily engage and support the needle support (4); c) a plurality of slots (8) longitudinally disposed at one substantial distal end of the needle support (4); and d) stoppers (5) provided at the barrel head (1a); wherein a fluid is injected by a first stroke of the plunger (2) under normal load; and an additional load is applied to the plunger (2) to compress the piston gasket (3) so that the plunger head (7) of the plunger (2) travels further to break the bone structures (6) for subsequent retraction of the needle support (4) on a second stroke.
摘要翻译：本发明涉及具有中空筒体（1），柱塞（2）和可拆卸针头支撑件（4）的安全注射器（100），其特征在于，安全注射器（100）包括： a）与柱塞（2）的柱塞头（7）过盈配合的活塞衬垫（3）; b）设置在所述中空筒体（1）的所述筒头部（1a）处的多个骨结构（6），以暂时接合和支撑所述针支撑件（4）; c）纵向设置在针支撑件（4）的一个实质远端的多个狭槽（8）; 和d）设置在枪头头部（1a）处的塞子（5）; 其中通过所述柱塞（2）的第一冲程在正常载荷下注入流体; 并且向柱塞（2）施加额外的负载以压缩活塞垫圈（3），使得柱塞（2）的柱塞头（7）进一步行进以破坏骨结构（6），以便随后针回缩支持（4）第二行程。

23. 发明授权

US09139485B2 Plant treatment agent 有权
标题翻译：植物处理剂
公开(公告)号：US09139485B2
公开(公告)日：2015-09-22
申请号：US14237790
申请日：2012-08-08
申请人： Ahmed Osumanu Haruna , Latifa Omar , Nik Muhamad Ab Majid
发明人： Ahmed Osumanu Haruna , Latifa Omar , Nik Muhamad Ab Majid
IPC分类号： C05F11/02 , C05C9/00 , C05G3/08 , A01N25/12 , C05G3/00 , A61K31/05 , A61K31/194
CPC分类号： C05G3/08 , A01N25/12 , A61K31/05 , A61K31/194 , C05C9/00 , C05C9/005 , C05F11/02 , C05G3/0058
摘要： The present invention provides a slow release granule composition for the delivery of one or more plant treatment agents. The composition comprises an organic solution consisting peat soil liquid obtained from a peat material and urea. The granule composition is useful for the controlled delivery of fertilizers and nutrients to plants and as a soil amendment. Also disclosed is a method of treating a plant with a plant treatment agent, comprising applying a slow release granule composition of the present invention and a method to prepare the slow release granule composition.
摘要翻译：本发明提供了用于递送一种或多种植物处理剂的缓释颗粒组合物。该组合物包含由泥炭材料和尿素获得的由泥炭土液体组成的有机溶液。颗粒组合物可用于控制向植物提供肥料和营养物质以及土壤修复。还公开了一种用植物处理剂处理植物的方法，包括施用本发明的缓释颗粒组合物和制备缓释颗粒组合物的方法。

24. 发明授权

US09028131B2 Method and apparatus for high intensity ultrasonic treatment of baking materials 有权
标题翻译：焙烧材料高强度超声波处理方法及装置
公开(公告)号：US09028131B2
公开(公告)日：2015-05-12
申请号：US13878002
申请日：2011-10-05
申请人： Ling Nyuk Chin , Ching Mei Tan , Nasrul Fikry Che Pa , Yus Aniza Yusof
发明人： Ling Nyuk Chin , Ching Mei Tan , Nasrul Fikry Che Pa , Yus Aniza Yusof
IPC分类号： A21C1/00 , A21D6/00 , B01F11/02 , A21C1/02 , A21C14/00
CPC分类号： A21D6/00 , A21C1/02 , A21C14/00 , B01F11/0283
摘要： The present invention discloses a high intensity ultrasonic treatment method and apparatus that is used in conjunction with an existing commercial dough or batter mixer to enhance the rheological, aeration and textural properties of the dough or batter. This change in properties is a result of the phenomenon of acoustic cavitation induced in the dough or batter by treatment with high intensity ultrasonic waves. The present invention discloses a mixing bowl (20) of an existing mixer system that is preloaded with dough or batter, the bowl (20) is located at the center of an ultrasonic bath tank (101) filled with a working fluid. The effect of ultra-sonic waves with power levels above 1 kW can be observed over the entire or partial mixing period of the dough or batter. The ultra-sonic waves of the present invention are generated by a plurality of ultrasonic wave generators (104A, 104B) and piezoelectric transducers (1) mounted on a stainless steel tank (101). The electrical energy received in each transducer (1) will be converted into appropriate mechanical expansion and contractions in the piezoelectric ceramics of the transducer (1) thus leading to pressure waves being transmitted to the dough or batter to be mixed. The generation and transmission of high intensity ultrasonic waves to the dough or batter affects its rheological, aeration and textural properties.
摘要翻译：本发明公开了一种与现有的商业面团或面糊混合器结合使用的高强度超声处理方法和装置，以增强面团或面糊的流变性，通气性和纹理性能。性能的这种变化是由高强度超声波处理在面团或面糊中引起的声空穴现象的结果。本发明公开了一种现有的混合器系统的混合碗（20），其预先装有面团或面糊，碗（20）位于填充有工作流体的超声波浴槽（101）的中心。在面团或面糊的整个或部分混合期间，可以观察到功率水平高于1kW的超声波的效果。本发明的超声波由安装在不锈钢罐（101）上的多个超声波发生器（104A，104B）和压电换能器（1）产生。在每个换能器（1）中接收的电能将被转换成在换能器（1）的压电陶瓷中适当的机械膨胀和收缩，从而导致压力波被传递到要混合的面团或面糊。高强度超声波向面团或面糊的产生和传播会影响其流变，曝气和纹理特性。

25. 发明申请

US20150111285A1 DETERGENT FORMULATION FOR DISHWASHING MACHINE 审中-公开
标题翻译：洗衣机洗涤剂配方
公开(公告)号：US20150111285A1
公开(公告)日：2015-04-23
申请号：US14398077
申请日：2013-05-02
申请人： Universiti Putra Malaysia (UPM)
发明人： Raja Noor Zaliha Raja Abdul Rahman , Abu Bakar Salleh , Mahiran Basri , Izuddin Abdul Rahman
IPC分类号： C11D1/66 , C11D3/386 , A47L15/44 , C11D3/22 , C11D3/10 , C11D3/04 , C11D11/00 , C11D3/37
CPC分类号： C11D1/662 , A47L15/44 , C11D1/66 , C11D3/046 , C11D3/10 , C11D3/225 , C11D3/3757 , C11D3/386 , C11D3/38627 , C11D3/3869 , C11D11/0023
摘要： The objective of the present invention is in the field of cleaning agent in particular detergents. In particular, it relates to a novel detergent formulation for an automatic dishwashing. The formulation provides excellent cleaning and finishing; it is environmentally friendlier than traditional compositions and allows for a more energy efficient automatic dishwashing process.
摘要翻译：本发明的目的在于清洁剂特别是洗涤剂领域。特别地，它涉及一种用于自动洗碗的新型洗涤剂配方。该配方提供优良的清洁和整理; 它比传统组合物更环保，并且允许更节能的自动洗碗过程。

26. 发明申请

US20140245801A1 PLANT TREATMENT AGENT 有权
标题翻译：植物处理剂
公开(公告)号：US20140245801A1
公开(公告)日：2014-09-04
申请号：US14237790
申请日：2012-08-08
申请人： Ahmed Osumanu Haruna , Latifa Omar , Nik Muhamad Ab Majid
发明人： Ahmed Osumanu Haruna , Latifa Omar , Nik Muhamad Ab Majid
IPC分类号： C05G3/08
CPC分类号： C05G3/08 , A01N25/12 , A61K31/05 , A61K31/194 , C05C9/00 , C05C9/005 , C05F11/02 , C05G3/0058
摘要： The present invention provides a slow release granule composition for the delivery of one or more plant treatment agents. The composition comprises an organic solution consisting peat soil liquid obtained from a peat material and urea. The granule composition is useful for the controlled delivery of fertilizers and nutrients to plants and as a soil amendment. Also disclosed is a method of treating a plant with a plant treatment agent, comprising applying a slow release granule composition of the present invention and a method to prepare the slow release granule composition.
摘要翻译：本发明提供了用于递送一种或多种植物处理剂的缓释颗粒组合物。该组合物包含由泥炭材料和尿素获得的由泥炭土液体组成的有机溶液。颗粒组合物可用于控制向植物提供肥料和营养物质以及土壤修复。还公开了一种用植物处理剂处理植物的方法，包括施用本发明的缓释颗粒组合物和制备缓释颗粒组合物的方法。

27. 发明授权

US08722099B2 Porous bioceramic composition for bone repair 失效
标题翻译：多孔生物陶瓷组合物用于骨修复
公开(公告)号：US08722099B2
公开(公告)日：2014-05-13
申请号：US14040632
申请日：2013-09-28
申请人： Universiti Putra Malaysia
发明人： Md Zuki Abu Bakar , Bahaa Fakri Hussein , Noordin Mohamed Mustapha , Norimah Yusof , Elias Saion
IPC分类号： A61K35/56
CPC分类号： A61L27/3637 , A61L27/3604 , A61L27/446 , A61L27/56 , A61L2430/02
摘要： The present invention relates to a porous bioceramic composition for bone repair and method of fabrication of the same. 3D-scaffolds were fabricated with a novel micro- and macro-architecture. Porous scaffolds based on dextrin, dextran, gelatin and biomineral (CaCO3) powder were fabricated by heating and freeze-drying methods. Fabrication of different compositions of porous scaffolds (20, 30 wt % of gelatin, 20, 40 wt % dextrin, 30, 40, 50, 60 wt % dextran bounder with the constant quantity of CaCO3 50 g). The scaffolds properties were characterized by x-ray diffraction (XRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and compression tests.
摘要翻译：本发明涉及一种用于骨修复的多孔生物陶瓷组合物及其制造方法。使用新的微观和宏观结构制造3D支架。通过加热和冷冻干燥方法制备基于糊精，葡聚糖，明胶和生物矿物质（CaCO3）粉末的多孔支架。制备多孔支架的不同组成（20,30重量％的明胶，20-40重量％的糊精，30,40,50,60重量％的葡聚糖束缚剂，恒定量的CaCO 3 50克）。通过X射线衍射（XRD），差示扫描量热法（DSC），扫描电子显微镜（SEM）和压缩测试来表征支架特性。

28. 发明申请

US20140027939A1 POROUS BIOCERAMIC COMPOSITION FOR BONE REPAIR 失效
标题翻译：用于骨修复的多孔生物组合物
公开(公告)号：US20140027939A1
公开(公告)日：2014-01-30
申请号：US14040632
申请日：2013-09-28
申请人： UNIVERSITI PUTRA MALAYSIA
发明人： Md Zuki ABU BAKAR , Bahaa Fakri HUSSEIN , Noordin MOHAMED MUSTAPHA , Norimah YUSOF , Elias SAION
IPC分类号： A61L27/56 , A61L27/36
CPC分类号： A61L27/3637 , A61L27/3604 , A61L27/446 , A61L27/56 , A61L2430/02
摘要： The present invention relates to a porous bioceramic composition for bone repair and method of fabrication of the same. 3D-scaffolds were fabricated with a novel micro- and macro-architecture. Porous scaffolds based on dextrin, dextran, gelatin and biomineral (CaCO3) powder were fabricated by heating and freeze-drying methods. Fabrication of different compositions of porous scaffolds (20, 30 wt % of gelatin, 20, 40 wt % dextrin, 30, 40, 50, 60 wt % dextran bounder with the constant quantity of CaCO3 50 g). The scaffolds properties were characterised by x-ray diffraction (XRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and compression tests.Most illustrative figure is FIG. 1.
摘要翻译：本发明涉及一种用于骨修复的多孔生物陶瓷组合物及其制造方法。使用新的微观和宏观结构制造3D支架。通过加热和冷冻干燥方法制备基于糊精，葡聚糖，明胶和生物矿物质（CaCO3）粉末的多孔支架。制备多孔支架的不同组成（20,30重量％的明胶，20-40重量％的糊精，30,40,50,60重量％的葡聚糖束缚剂，恒定量的CaCO 3 50克）。通过X射线衍射（XRD），差示扫描量热法（DSC），扫描电子显微镜（SEM）和压缩测试来表征支架特性。最具说明性的图是图1。 1。

29. 发明申请

US20130330432A1 USES OF CURCULIGO LATIFOLIA (C. LATIFOLIA) EXTRACTS 审中-公开
标题翻译： CURCULIGO LATIFOLIA（C. LATIFOLIA）提取物的使用
公开(公告)号：US20130330432A1
公开(公告)日：2013-12-12
申请号：US13967883
申请日：2013-08-15
申请人： Maznah Ismail , Nur Akmal Ishak , Muhajir Hamid
发明人： Maznah Ismail , Nur Akmal Ishak , Muhajir Hamid
IPC分类号： A61K36/88
CPC分类号： A61K36/88 , A61K36/896 , A61K2236/331
摘要： The present invention relates to Curculigo latifolia (C. latifolia) extracts, wherein the extracts extracted from different parts of a plant such as fruits, roots and leaves, individually and in any combinations thereof, characterized in that the extracts are used as an agent for treating and preventing metabolic disorder diseases such as diabetes mellitus, obesity, cardiovascular, and atherosclerosis.
摘要翻译：本发明涉及花椰菜（C. latifolia）提取物，其中从植物的不同部分提取的提取物，例如水果，根和叶，其单独和任意组合，其特征在于，提取物用作治疗和预防代谢障碍疾病如糖尿病，肥胖，心血管和动脉粥样硬化。

30. 发明申请

US20120058207A1 ANTI-DIABETIC NUTRACEUTICAL COMPOSITION FROM PALM LEAF EXTRACT 审中-公开
标题翻译：来自棕榈叶提取物的抗糖尿病营养成分
公开(公告)号：US20120058207A1
公开(公告)日：2012-03-08
申请号：US13260188
申请日：2009-03-24
申请人： Suhaila Mohamed , Rosalina Tan Roslan Tan
发明人： Suhaila Mohamed , Rosalina Tan Roslan Tan
IPC分类号： A61K36/889 , A61P39/06 , A61P43/00 , A61P3/00 , A61P13/12 , A61P25/00 , A61P27/02 , A61P3/10 , A61P9/00
CPC分类号： A61K36/889 , A23L33/105 , A23V2002/00
摘要： A comestible composition with anti-diabetic property which is effective in lowering the blood glucose and help reduce oxidative stress in diabetics and have anti-diabetic properties that protect against diabetic complications, retarding diabetes related organ degeneration and effective to hinder or prevent ailments or conditions resulting from, or exacerbated by, a chronic increase in blood sugar including: tissue degeneration, cardiovascular disease, kidney degeneration, loss of cognitive function, weight loss, visual impairment, and vasomotor symptoms which contains extract from palm leaf.
摘要翻译：一种具有抗糖尿病性质的食物组合物，其有效降低血糖并有助于减少糖尿病患者的氧化应激，并具有抗糖尿病性质，可防止糖尿病并发症，阻止糖尿病相关器官变性并有效阻止或预防所产生的疾病或病症来自或加剧血糖的慢性增加，包括：包括来自棕榈叶的提取物的组织变性，心血管疾病，肾变性，认知功能丧失，体重减轻，视觉障碍和血管舒缩症状。

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