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21. 发明授权

US08314640B2 Driver circuit 失效
标题翻译：驱动电路
公开(公告)号：US08314640B2
公开(公告)日：2012-11-20
申请号：US13110917
申请日：2011-05-19
申请人： Song-Lin Tong , Qi-Yan Luo , Peng Chen , Yun Bai
发明人： Song-Lin Tong , Qi-Yan Luo , Peng Chen , Yun Bai
IPC分类号： H03L7/00
CPC分类号： G06F1/26
摘要： A driver circuit drives a pulse width modulation (PWM) controller. The driver circuit includes an enabling circuit, a power supply input control circuit, a stabilizing circuit, and a discharge circuit. The stabilizing circuit is electrically connected to the PWM controller. The power supply input control circuit is electrically connected between the enabling circuit and the stabilizing circuit. The discharge circuit is electrically connected between the stabilizing circuit and the ground. In response to the driver circuit working in normal operation, the enabling circuit enables the power supply input control circuit to output a working voltage to the stabilizing circuit, and in response to the process of the driver circuit restarting, the enabling circuit enables the power supply input to stop outputting power supply to the stabilizing circuit. The discharge circuit leads a residual voltage of the stabilizing circuit to the ground, during the process of the driver circuit being restarted.
摘要翻译：驱动电路驱动脉宽调制（PWM）控制器。驱动器电路包括使能电路，电源输入控制电路，稳定电路和放电电路。稳压电路与PWM控制器电连接。电源输入控制电路电连接在使能电路和稳定电路之间。放电电路电连接在稳压电路和地之间。响应于驱动电路正常工作，使能电路使得电源输入控制电路向稳定电路输出工作电压，并且响应于驱动电路重新启动的过程，使能电路使电源输入停止向稳定电路输出电源。在驱动器电路重新启动的过程中，放电电路将稳定电路的剩余电压引向地。

22. 发明申请

US20090042777A1 G-CSF Transferrin Fusion Proteins 有权
标题翻译： G-CSF转铁蛋白融合蛋白
公开(公告)号：US20090042777A1
公开(公告)日：2009-02-12
申请号：US10575033
申请日：2004-10-08
申请人： Wei-Chiang Shen , Yun Bai , David Ann , Adam Widera
发明人： Wei-Chiang Shen , Yun Bai , David Ann , Adam Widera
IPC分类号： A61K38/00 , C07K14/00 , C12N15/11 , C12P21/04 , A61P31/00 , A61K31/7088 , C12N5/06
CPC分类号： C07K19/00 , A61K38/193 , A61K47/644 , C07K14/535 , C07K14/79 , C07K2319/10 , C07K2319/74
摘要： A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
摘要翻译：包含可操作地连接到Tf结构域的G-CSF结构域的多肽，其中所述多肽被转运到表达TfR基因的细胞中的能力或通过细胞内吞作用跨越表达TfR基因的细胞转运的能力是高于单独的G-CSF结构域。

23. 发明授权

US08456172B2 Measurement circuit for capacitor 失效
标题翻译：电容测量电路
公开(公告)号：US08456172B2
公开(公告)日：2013-06-04
申请号：US12981507
申请日：2010-12-30
申请人： Qi-Yan Luo , Song-Lin Tong , Peng Chen , Yun Bai
发明人： Qi-Yan Luo , Song-Lin Tong , Peng Chen , Yun Bai
IPC分类号： G01R31/12
CPC分类号： G01R31/028 , G01R31/025
摘要： A measurement circuit includes a switch unit with a number of keys selectively pressed to output different resistance regulating signals. A resistance setting circuit receives the resistance regulating signals and connects different resistances to a voltage circuit and a current circuit. The voltage circuit outputs different voltages. The current voltage receives a voltage from the voltage circuit and outputs a current to a capacitor. A detecting circuit measures a temperature of the capacitor and outputs the temperature to the resistance setting circuit. The resistance setting circuit compares the received temperature with a preset temperature. If the received temperature is equal to or greater than the preset temperature, the resistance setting circuit outputs short-circuit information of the capacitor. If the received temperature is less than the preset temperature, the resistance setting circuit outputs normal information of the capacitor. A display unit displays the information of the capacitor.
摘要翻译：测量电路包括具有多个键的开关单元，其被选择性地按压以输出不同的电阻调节信号。电阻设定电路接收电阻调节信号，并将不同的电阻连接到电压电路和电流电路。电压电路输出不同的电压。电流电压从电压电路接收电压并向电容器输出电流。检测电路测量电容器的温度并将温度输出到电阻设定电路。电阻设定电路将接收到的温度与预设温度进行比较。如果接收到的温度等于或大于预设温度，则电阻设定电路输出电容器的短路信息。如果接收到的温度低于预设温度，则电阻设定电路输出电容器的正常信息。显示单元显示电容器的信息。

24. 发明授权

US08188032B2 G-CSF transferrin fusion proteins 有权
标题翻译： G-CSF转铁蛋白融合蛋白
公开(公告)号：US08188032B2
公开(公告)日：2012-05-29
申请号：US10575033
申请日：2004-10-08
申请人： Wei-Chiang Shen , Yun Bai , David Ann , Adam Widera
发明人： Wei-Chiang Shen , Yun Bai , David Ann , Adam Widera
IPC分类号： A61K38/00 , A61P7/06
CPC分类号： C07K19/00 , A61K38/193 , A61K47/644 , C07K14/535 , C07K14/79 , C07K2319/10 , C07K2319/74
摘要： A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
摘要翻译：包含可操作地连接到Tf结构域的G-CSF结构域的多肽，其中所述多肽被转运到表达TfR基因的细胞中的能力或通过细胞内吞作用跨越表达TfR基因的细胞转运的能力是高于单独的G-CSF结构域。

25. 发明申请

US20120041294A1 Individually Adjustable Multi-channel Systems in vivo Recording 审中-公开
标题翻译：单独可调多通道系统体内记录
公开(公告)号：US20120041294A1
公开(公告)日：2012-02-16
申请号：US12856960
申请日：2010-08-16
申请人： Yun Bai
发明人： Yun Bai
IPC分类号： A61B5/0478 , A61B5/0476
CPC分类号： A61B5/0478 , A61B5/6868 , A61B2562/028 , A61B2562/046
摘要： In vivo multi-channel recording is a powerful tool in exploring the real time neural activity associated with specific behavioral outputs. A prominent strength of this technique is that a large number of neurons can be, in theory, simultaneously recorded such that the activity of a small neural circuitry can be formulated and assessed. The present application provides for a new, adjustable multi-electrode system (AMES). Electrodes in this AMES, once installed into the brain, can be individually adjusted such that each electrode can be independently protruded until it reaches an optimal position to acquire neuronal signals. Thus, every electrode within the multi-electrode system is able to acquire valid signals. This adjustable multi-electrode system substantially improves the efficacy of signal acquisition and offers an unprecedented power for in vivo recordings.
摘要翻译：体内多通道记录是探索与特定行为输出相关的实时神经活动的有力工具。这种技术的突出优点是在理论上可以同时记录大量神经元，使得可以配制和评估小神经电路的活性。本申请提供了一种新的可调多电极系统（AMES）。该AMES中的电极一旦被安装到大脑中，可以被单独调节，使得每个电极可以独立地突出，直到它达到获得神经元信号的最佳位置。因此，多电极系统内的每个电极能够获得有效的信号。这种可调整的多电极系统大大提高了信号采集的功效，为体内记录提供了前所未有的功率。

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