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21. 发明授权

US08666513B2 Implantable lead with shielding 失效
标题翻译：可植入铅带屏蔽
公开(公告)号：US08666513B2
公开(公告)日：2014-03-04
申请号：US12328515
申请日：2008-12-04
申请人： Masoud Ameri , Arthur J. Foster
发明人： Masoud Ameri , Arthur J. Foster
IPC分类号： A61N1/372
CPC分类号： A61N1/05 , A61N1/086
摘要： Medical device leads with magnetic shielding and methods of shielding medical device leads from magnetic fields during medical procedures such as magnetic resonance imaging (MRI) are described. An illustrative implantable medical device includes a lead including a lead conductor having a length and a helically coiled ribbon shield radially surrounding the lead conductor along at least a portion of the length of the lead. The ribbon shield can include one or more inner ribbon conductors and/or one or more outer ribbon conductors. The outer ribbon conductor can have a variable width (e.g., a necked-down configuration, an arrowhead configuration, or an undulating configuration) along the length of the lead. In some cases, the helically coiled ribbon has a variable pitch along the length of the lead that may be the same as or different from that of the lead conductor pitch.
摘要翻译：描述了医疗装置引线的磁屏蔽和医疗装置引线在磁共振成像（MRI）等医疗过程中屏蔽磁场的方法。示例性可植入医疗装置包括引线，该引线包括引线导体，引线导体具有沿导线长度的至少一部分具有长度和螺旋状卷绕的带状屏蔽件，沿着引线导体径向包围引线导体。带状屏蔽件可以包括一个或多个内部带状导体和/或一个或多个外部带状导体。外带状导体可以具有沿引线长度的可变宽度（例如，颈缩配置，箭头配置或起伏构型）。在一些情况下，螺旋卷绕的带沿引线的长度具有可变的间距，其可以与引线导体间距的相同或不同。

22. 发明授权

US08335572B2 Medical device lead including a flared conductive coil 有权
标题翻译：医疗器械引线包括喇叭形导电线圈
公开(公告)号：US08335572B2
公开(公告)日：2012-12-18
申请号：US12843573
申请日：2010-07-26
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/086
摘要： An implantable medical device lead includes an insulative lead body, an outer conductive coil extending through the lead body, and an inner conductive coil extending coaxially with the outer conductive coil. The outer conductive coil, which is coupled to a proximal electrode at a distal end of the outer conductive coil, has a first outer conductive coil diameter. The inner conductive coil is coupled to a distal electrode at a distal end of the inner conductive coil. The inner conductive coil includes a filar having a filar diameter and a coil pitch that is about one to one and a half times the filar diameter. The inner conductive coil transitions from a first inner conductive coil diameter to a larger second inner conductive coil diameter between the proximal electrode and the distal electrode.
摘要翻译：可植入医疗器件引线包括绝缘引线体，延伸穿过引线体的外部导电线圈和与外部导电线圈同轴延伸的内部导电线圈。外导电线圈，其耦合到外导电线圈的远端处的近端电极，具有第一外导电线圈直径。内部导电线圈在内部导电线圈的远端处联接到远端电极。内导电线圈包括具有丝直径和线圈间距的丝状体，其长度大约为丝直径的一倍和1/2倍。内部导电线圈从近端电极和远端电极之间的第一内部导电线圈直径转换到较大的第二内部导电线圈直径。

23. 发明授权

US08255055B2 MRI shielding in electrodes using AC pacing 有权
标题翻译：使用AC起搏的电极中的MRI屏蔽
公开(公告)号：US08255055B2
公开(公告)日：2012-08-28
申请号：US12367457
申请日：2009-02-06
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/086 , A61N2001/0585
摘要： A medical device includes a pulse generator, an electrode configured to contact tissue in a coronary vessel, a lead comprising a lead conductor, the lead conductor connecting the pulse generator with the electrode, and a filter circuit electrically connected in series between the lead conductor and the electrode. The filter circuit may include a band pass filter that attenuates signals having a frequency other than a natural resonance frequency (e.g. MRI device signals), and the pulse generator may transmit therapy signals to the electrode as a sinusoidal voltage wave at the natural resonance frequency. The filter circuit may include a diode that rectifies the sinusoidal voltage wave before the rectified sinusoidal voltage wave passes to the electrode. In some embodiments, therapy signals may be provided to the electrode through the band pass filter over a natural resonance frequency range.
摘要翻译：医疗装置包括脉冲发生器，构造成接触冠状血管中的组织的电极，包括引线导体的引线，将脉冲发生器与电极连接的引线导体和串联电连接在引线导体和电极。滤波器电路可以包括衰减具有不同于固有谐振频率的频率（例如MRI装置信号）的信号的带通滤波器，并且脉冲发生器可以将治疗信号作为正弦电压波以固有谐振频率发送到电极。滤波器电路可以包括在整流的正弦电压波通过电极之前对正弦电压波进行整流的二极管。在一些实施例中，治疗信号可以在固有共振频率范围内通过带通滤波器提供给电极。

24. 发明申请

US20120071941A1 SELECTIVELY CONNECTING THE TIP ELECTRODE DURING THERAPY FOR MRI SHIELDING 有权
标题翻译：在治疗期间选择性地连接提示电极用于MRI屏蔽
公开(公告)号：US20120071941A1
公开(公告)日：2012-03-22
申请号：US13302715
申请日：2011-11-22
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/362 , A61N1/05
CPC分类号： A61N1/056 , A61N1/086 , A61N1/3718
摘要： A medical device includes a pulse generator and an electrode configured to contact tissue in a body vessel. The medical device includes a lead that includes a lead connector. The lead connector connects a pulse generator with an electrode via a conductive path. An electrode switch is electrically connected between the lead conductor and the electrode. The electrode switch includes an open state preventing the conductive path between the lead and the electrode. The electrode switch includes a closed state establishing the conductive path between the lead and the electrode when a voltage is applied across the electrode switch that exceeds a threshold voltage. The electrode switch in the open state electrically shields the electrode from electromagnetic radiation and induced voltages during magnetic resonance imaging.
摘要翻译：医疗装置包括脉冲发生器和构造成接触身体血管中的组织的电极。医疗装置包括引线，其包括引线连接器。引线连接器通过导电路径将脉冲发生器与电极连接。电极开关电连接在引线导体和电极之间。电极开关包括阻止引线和电极之间的导电路径的开放状态。当跨越电极开关的电压超过阈值电压时，电极开关包括建立在引线和电极之间的导电路径的关闭状态。处于断开状态的电极开关在磁共振成像期间电屏蔽电磁辐射和感应电压。

25. 发明申请

US20110087299A1 MEDICAL DEVICE LEAD INCLUDING A FLARED CONDUCTIVE COIL 有权
标题翻译：医疗器械引导线，包括一个插入式导线线圈
公开(公告)号：US20110087299A1
公开(公告)日：2011-04-14
申请号：US12843573
申请日：2010-07-26
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/056 , A61N1/086
摘要： An implantable medical device lead includes an insulative lead body, an outer conductive coil extending through the lead body, and an inner conductive coil extending coaxially with the outer conductive coil. The outer conductive coil, which is coupled to a proximal electrode at a distal end of the outer conductive coil, has a first outer conductive coil diameter. The inner conductive coil is coupled to a distal electrode at a distal end of the inner conductive coil. The inner conductive coil includes a filar having a filar diameter and a coil pitch that is about one to one and a half times the filar diameter. The inner conductive coil transitions from a first inner conductive coil diameter to a larger second inner conductive coil diameter between the proximal electrode and the distal electrode.
摘要翻译：可植入医疗器件引线包括绝缘引线体，延伸穿过引线体的外部导电线圈和与外部导电线圈同轴延伸的内部导电线圈。外导电线圈，其耦合到外导电线圈的远端处的近端电极，具有第一外导电线圈直径。内部导电线圈在内部导电线圈的远端处联接到远端电极。内导电线圈包括具有丝直径和线圈间距的丝状体，其长度大约为丝直径的一倍和1/2倍。内部导电线圈从近端电极和远端电极之间的第一内部导电线圈直径转换到较大的第二内部导电线圈直径。

26. 发明申请

US20090149933A1 IMPLANTABLE LEAD HAVING A VARIABLE COIL CONDUCTOR PITCH 有权
标题翻译：可变导线，带有可变线圈导线器
公开(公告)号：US20090149933A1
公开(公告)日：2009-06-11
申请号：US12328490
申请日：2008-12-04
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/086 , H01F21/04 , H03H2001/0092 , H05K9/0098
摘要： Systems and methods for shielding implantable leads from magnetic fields during medical procedures such as magnetic resonance imaging (MRI) are described. In various embodiments, the lead includes an inner conductor that is helically shaped and radially surrounded, at least in part, by one or more outer shielding conductors. The pitch of the inner conductor, and in some cases also the outer conductor, can be varied (e.g., continuously or at certain points) along the length of the lead, forming a plurality of high impedance points along the length of the lead which result in the dissipation of electromagnetic energy at an interrogation frequency of a magnetic resonance imaging device (e.g., 64 MHz, 128 MHz, or the like). In some embodiments, the variance in the pitch of the inner conductor follows a sinusoidal function, a modified square-wave function, or some other repeating pattern.
摘要翻译：描述了在诸如磁共振成像（MRI）的医疗过程期间屏蔽来自磁场的可植入引线的系统和方法。在各种实施例中，引线包括内部导体，所述内部导体至少部分地由一个或多个外部屏蔽导体螺旋形并且径向包围。内部导体的间距，并且在一些情况下也可以是外部导体，可以沿着引线的长度变化（例如，连续地或在某些点），沿着引线的长度形成多个高阻抗点，从而导致在磁共振成像装置的询问频率（例如，64MHz，128MHz等）处的电磁能量的耗散。在一些实施例中，内部导体的间距的变化遵循正弦函数，修正的方波函数或一些其他重复模式。

27. 发明申请

US20090149906A1 METHOD AND APPARATUS FOR DISCONNECTING THE TIP ELECTRODE DURING MRI 有权
标题翻译：在MRI中断开TIP电极的方法和装置
公开(公告)号：US20090149906A1
公开(公告)日：2009-06-11
申请号：US12329383
申请日：2008-12-05
申请人： Masoud Ameri , Greg P. Carpenter , David C. Olson
发明人： Masoud Ameri , Greg P. Carpenter , David C. Olson
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/086 , A61N2001/0585 , Y10S128/901
摘要： A medical device includes a pulse generator, a lead, and an electrode. The lead includes an electrode and a lead conductor connecting the pulse generator with the electrode via first and second conductive paths. The medical device includes first and second switches. The first switch includes a non-conductive state in the presence of a magnetic field, the non-conductive state preventing formation of the first conductive path between the pulse generator and the electrode. The second switch includes a non-conductive state that prevents formation of the second conductive path between the pulse generator and the electrode. The first switch in the non-conductive state and the second switch in the non-conductive state electrically shields the electrode from electromagnetic radiation and induced voltages during a magnetic resonance imaging procedure.
摘要翻译：医疗装置包括脉冲发生器，引线和电极。引线包括通过第一和第二导电路径将脉冲发生器与电极连接的电极和引线导体。医疗装置包括第一和第二开关。第一开关包括在存在磁场的情况下的非导通状态，非导电状态阻止脉冲发生器和电极之间的第一导电路径的形成。第二开关包括防止在脉冲发生器和电极之间形成第二导电路径的非导电状态。在非导电状态的第一开关和非导电状态的第二开关在磁共振成像过程期间电屏蔽电磁辐射和感应电压。

28. 发明授权

US06308106B1 Feed-forward controller with delayed command input 有权
标题翻译：具有延迟命令输入的前馈控制器
公开(公告)号：US06308106B1
公开(公告)日：2001-10-23
申请号：US09243305
申请日：1999-02-02
申请人： Masoud Ameri , Donald A. Yost
发明人： Masoud Ameri , Donald A. Yost
IPC分类号： G05B1302
CPC分类号： G05B11/42
摘要： A system controller for a controllable system having an inherent time delay includes a delay module that receives a command input and provides a first output signal delayed in time from the command input. A feed-forward module also receives the command input, or a function thereof, and provides a second output signal intended to drive the system to a desired state. A first summer receives the delayed output signal and a feedback signal from the controllable system. The first summer combines the delayed signal and the feedback signal to provide a third output signal. A compensator module receives the third output signal and provides a fourth output signal. A second summer receives the second output signal and the fourth output signal. The second summer combines the second output signal and the fourth output signal to provide an input signal for the controllable system.
摘要翻译：具有固有时间延迟的可控系统的系统控制器包括延迟模块，其接收命令输入并提供从命令输入时间延迟的第一输出信号。前馈模块还接收命令输入或其功能，并提供旨在将系统驱动到期望状态的第二输出信号。第一个夏天接收延迟的输出信号和来自可控系统的反馈信号。第一个加法器结合延迟信号和反馈信号以提供第三输出信号。补偿器模块接收第三输出信号并提供第四输出信号。第二个夏天接收第二输出信号和第四输出信号。第二个夏天组合了第二输出信号和第四输出信号，以提供可控系统的输入信号。

29. 发明授权

US08897875B2 Selectively connecting the tip electrode during therapy for MRI shielding 有权
标题翻译：在MRI屏蔽治疗期间选择性地连接尖端电极
公开(公告)号：US08897875B2
公开(公告)日：2014-11-25
申请号：US13302715
申请日：2011-11-22
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08 , A61N1/37
CPC分类号： A61N1/056 , A61N1/086 , A61N1/3718
摘要： A medical device includes a pulse generator and an electrode configured to contact tissue in a body vessel. The medical device includes a lead that includes a lead connector. The lead connector connects a pulse generator with an electrode via a conductive path. An electrode switch is electrically connected between the lead conductor and the electrode. The electrode switch includes an open state preventing the conductive path between the lead and the electrode. The electrode switch includes a closed state establishing the conductive path between the lead and the electrode when a voltage is applied across the electrode switch that exceeds a threshold voltage. The electrode switch in the open state electrically shields the electrode from electromagnetic radiation and induced voltages during magnetic resonance imaging.
摘要翻译：医疗装置包括脉冲发生器和构造成接触身体血管中的组织的电极。医疗装置包括引线，其包括引线连接器。引线连接器通过导电路径将脉冲发生器与电极连接。电极开关电连接在引线导体和电极之间。电极开关包括阻止引线和电极之间的导电路径的开放状态。当跨越电极开关的电压超过阈值电压时，电极开关包括建立在引线和电极之间的导电路径的关闭状态。处于断开状态的电极开关在磁共振成像期间电屏蔽电磁辐射和感应电压。

30. 发明授权

US08311637B2 Magnetic core flux canceling of ferrites in MRI 有权
标题翻译： MRI中铁磁磁芯磁通消除
公开(公告)号：US08311637B2
公开(公告)日：2012-11-13
申请号：US12367452
申请日：2009-02-06
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/08 , A61N1/378
CPC分类号： A61N1/3718 , A61N2/002
摘要： A magnetic core flux canceling device according to embodiments of the present invention includes a magnetic field sensor adapted for placement at a ferrite material core in an implantable medical device, the magnetic field sensor adapted to transmit a signal corresponding to a magnitude of a first magnetic field. Such a device may also include a coil disposed around the ferrite material core and a driver circuit configured to receive the signal and to vary a voltage applied across the coil based on the signal, the voltage applied across the coil creating a second magnetic field at least partially in a direction opposite the first magnetic field. According to some embodiments of the present invention, multiple coils may be used to cancel magnetic fields in multiple directions. A voltage applied across the coil varies in magnitude and/or direction to cancel or weaken an MRI-related magnetic field.
摘要翻译：根据本发明的实施例的磁芯磁通量消除装置包括适于放置在可植入医疗装置中的铁氧体材料芯的磁场传感器，所述磁场传感器适于传输对应于第一磁场的大小的信号。这种装置还可以包括设置在铁氧体材料芯周围的线圈和驱动电路，驱动电路被配置为基于信号接收信号和改变施加在线圈上的电压，施加在线圈两端的电压至少产生第二磁场部分地在与第一磁场相反的方向上。根据本发明的一些实施例，可以使用多个线圈来消除多个方向上的磁场。施加在线圈上的电压在幅度和/或方向上变化以抵消或削弱与MRI相关的磁场。

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