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    • 21. 发明申请
    • Virtual-Slide Creating Device
    • 虚拟幻灯片创建设备
    • US20110221881A1
    • 2011-09-15
    • US13042178
    • 2011-03-07
    • Tetsuya ShirotaTakashi YoneyamaChika NakajimaYasuaki Natori
    • Tetsuya ShirotaTakashi YoneyamaChika NakajimaYasuaki Natori
    • H04N7/18
    • G02B21/367G02B21/26
    • It is possible to create a virtual slide of a subject of observation in a simple configuration without setting a movement pattern in advance. Provided is a virtual-slide creating device including a stage on which a sample is mounted; an objective lens that collects light from the sample; a relative movement mechanism that moves at least one of these components relative to each other in a direction crossing the optical axis of the objective lens; a position detecting unit that obtains relative position information of the stage and the objective lens; an image capturing unit that acquires a partial enlarged image of the sample; a display unit that displays the enlarged image acquired; an image saving unit that saves an enlarged image acquired by the image capturing unit each time at least one of the stage and the objective lens is moved relative to each other by a predetermined distance, based on the relative position information obtained; and an image processing unit that creates a virtual slide by forming an array of saved enlarged images based on the relative position information detected.
    • 可以以简单的配置创建观察对象的虚拟幻灯片,而无需事先设置移动模式。 提供了一种虚拟幻灯片创建装置,其包括安装有样本的阶段; 从样品中收集光的物镜; 相对运动机构,其在与物镜的光轴交叉的方向上相对于彼此移动这些部件中的至少一个; 位置检测单元,其获得所述平台和所述物镜的相对位置信息; 获取所述样本的部分放大图像的图像捕获单元; 显示所获取的放大图像的显示单元; 图像保存单元,其基于所获得的相对位置信息,每次使所述舞台和所述物镜中的至少一个相对于彼此移动预定距离,从而保存由所述摄像单元获取的放大图像; 以及图像处理单元,其基于检测到的相对位置信息,通过形成保存的放大图像的阵列来创建虚拟幻灯片。
    • 22. 发明授权
    • Virtual slide generation device, virtual slide generation method, virtual slide generation program product and virtual slide generation program transmission medium
    • 虚拟幻灯片生成设备,虚拟幻灯片生成方法,虚拟幻灯片生成程序产品和虚拟幻灯片生成程序传输介质
    • US08000560B2
    • 2011-08-16
    • US12011355
    • 2008-01-25
    • Tetsuya Shirota
    • Tetsuya Shirota
    • G06K9/36G06K9/00
    • G06K9/00134G06K2009/2045
    • In a virtual slide generation device for generating a virtual slide by patching/combining a plurality of observation images obtained by shooting and picking up an observation object observed by a microscope, by comprising an image patching/combination information calculation unit for calculating image patching/combination information about an area overlapping between observation images for the patching/combination on the basis of a plurality of observation images shot and picked up by a first observation method and an image patching/combination unit for patching and combining a plurality of image areas shot and picked up by a second observation method on the basis of the image patching/combination information calculated by the image patching/combination information calculation unit, image patching/combination computation by a plurality of microscopic examination methods can be reduced, thereby more particularly preventing the fading when shooting and picking up a fluorescence (FL) observation image and obtaining a high-quality image.
    • 在虚拟幻灯片生成装置中,通过对通过拍摄获取的多个观察图像进行修补/合成来生成虚拟幻灯片,并且拾取由显微镜观察到的观察对象,通过包括用于计算图像修补/组合的图像修补/组合信息计算单元 基于通过第一观察方法拍摄和拾取的多个观察图像的补丁/组合的观察图像之间的重叠区域的信息和用于修补和组合拍摄和拾取的多个图像区域的图像补丁/组合单元 根据由图像补丁/组合信息计算单元计算的图像补丁/组合信息,通过第二观察方法,可以减少通过多个显微镜检查方法的图像修补/组合计算,从而更具体地防止当 拍摄和拾取荧光(FL) 欣赏图像并获得高质量的图像。
    • 23. 发明申请
    • Virtual slide generation device, virtual slide generation method, virtual slide generation program product and virtual slide generation program transmission medium
    • 虚拟幻灯片生成设备,虚拟幻灯片生成方法,虚拟幻灯片生成程序产品和虚拟幻灯片生成程序传输介质
    • US20080187208A1
    • 2008-08-07
    • US12011355
    • 2008-01-25
    • Tetsuya Shirota
    • Tetsuya Shirota
    • G06K9/36
    • G06K9/00134G06K2009/2045
    • In a virtual slide generation device for generating a virtual slide by patching/combining a plurality of observation images obtained by shooting and picking up an observation object observed by a microscope, by comprising an image patching/combination information calculation unit for calculating image patching/combination information about an area overlapping between observation images for the patching/combination on the basis of a plurality of observation images shot and picked up by a first observation method and an image patching/combination unit for patching and combining a plurality of image areas shot and picked up by a second observation method on the basis of the image patching/combination information calculated by the image patching/combination information calculation unit, image patching/combination computation by a plurality of microscopic examination methods can be reduced, thereby more particularly preventing the fading when shooting and picking up a fluorescence (FL) observation image and obtaining a high-quality image.
    • 在虚拟幻灯片生成装置中,通过对通过拍摄获取的多个观察图像进行修补/合成来生成虚拟幻灯片,并且拾取由显微镜观察到的观察对象,通过包括用于计算图像修补/组合的图像修补/组合信息计算单元 基于通过第一观察方法拍摄和拾取的多个观察图像的补丁/组合的观察图像之间的重叠区域的信息和用于修补和组合拍摄和拾取的多个图像区域的图像补丁/组合单元 根据由图像补丁/组合信息计算单元计算的图像补丁/组合信息,通过第二观察方法,可以减少通过多个显微镜检查方法的图像修补/组合计算,从而更具体地防止当 拍摄和拾取荧光(FL) 欣赏图像并获得高质量的图像。
    • 24. 发明授权
    • Image sensing apparatus for microscope
    • 显微镜摄像装置
    • US06876399B1
    • 2005-04-05
    • US09483521
    • 2000-01-14
    • Hideyuki MasuyamaTetsuya Shirota
    • Hideyuki MasuyamaTetsuya Shirota
    • G02B21/36H04N9/73H04N5/46H04N9/64
    • H04N9/735G02B21/361G02B21/365
    • An image sensing apparatus for a microscope of this invention includes an image sensing unit for sensing an observation image obtained by a microscope and obtaining the observation image, a microscopy technique determination unit for detecting a microscopy technique in the microscope, a chromaticity determination unit for determining chromaticity of the observation image on the basis of the microscopy technique detected by said microscopy technique determination unit, and determining a region where color balance is adjusted in the observation image, and a color balance adjustment unit for adjusting color balance in accordance with a color balance adjustment amount arbitrarily set for the region of the observation image determined by said chromaticity determination unit.
    • 本发明的显微镜摄像装置包括:感光单元,用于感测由显微镜得到的观察图像,得到观察图像;显微镜技术判定单元,用于检测显微镜中的显微镜技术;色度判定单元, 基于由所述显微技术确定单元检测到的显微镜技术的观察图像的色度,以及确定在观察图像中调整色彩平衡的区域,以及用于根据颜色平衡调整色彩平衡的色彩平衡调节单元 由所述色度确定单元确定的观察图像的区域任意设置的调整量。
    • 26. 发明授权
    • Microscope system
    • 显微镜系统
    • US08649088B2
    • 2014-02-11
    • US12940158
    • 2010-11-05
    • Tetsuya Shirota
    • Tetsuya Shirota
    • G02B21/00
    • G02B21/248G02B21/24G02B21/368
    • A microscope system stores, for each objective, the movement control information including a type flag indicating the type of an objective depending on the presence/absence of a soak or a type of the soak and a save distance for saving the stage or the objective switch unit by a predetermined distance. When a switch direction of objectives is input, and when there is a change in the type of the objective after the switch, the system stops an operation after the stage or the objective switch unit is moved according to the save distance, and recovers the stage or the objective switch unit to an original position after the operation direction input unit inputs an operation direction for the stage and the objective switch unit.
    • 显微镜系统针对每个目标存储包括表示目标类型的类型标志的移动控制信息,所述类型标志根据浸泡的存在/不存在或浸泡的类型以及用于保存平台或目标开关的保存距离 单位预定距离。 当物体的切换方向被输入时,并且当切换后目标类型发生变化时,系统在舞台或物镜切换单元根据保存距离移动后停止操作,并且恢复舞台 或物镜开关单元在操作方向输入单元输入用于平台和物镜开关单元的操作方向之后到原始位置。
    • 27. 发明申请
    • MICROSCOPE SYSTEM
    • 微观系统
    • US20120293864A1
    • 2012-11-22
    • US13562855
    • 2012-07-31
    • Hideyuki KawanabeTetsuya ShirotaYasuko IshiiTakashi Yoneyama
    • Hideyuki KawanabeTetsuya ShirotaYasuko IshiiTakashi Yoneyama
    • G02B21/06
    • G01N21/6458G02B21/241G02B21/361G02B21/365
    • A microscope system that is capable of changing a status of observation of a sample comprises an instruction unit for giving instruction for driving one or more optical members including an objective lens or for changing a relative position of the sample and the objective lens; and an image capturing unit for capturing an observed image of the sample as a still image or a live image. The microscope system changes an order for performing operations in accordance with the instruction from the instruction unit, the operations including an operation of driving the one or more optical members or changing the relative position; an operation of switching the illumination light for the sample from being cut-off or reduced to being applied; and an operation of switching the image displayed in a display unit from the still image to the live image.
    • 能够改变样本的观察状态的显微镜系统包括指示单元,用于指示用于驱动包括物镜的一个或多个光学构件或用于改变样品和物镜的相对位置; 以及用于捕获作为静止图像或实况图像的样本的观察图像的图像捕获单元。 显微镜系统根据来自指示单元的指令改变执行操作的顺序,操作包括驱动一个或多个光学构件的操作或改变相对位置; 将样品的照明光切换或减少到施加的操作; 以及将从显示单元显示的图像从静止图像切换到实时图像的操作。
    • 28. 发明授权
    • Microscope system and method for synthesizing microscopic images
    • 显微镜系统和微观图像合成方法
    • US08014579B2
    • 2011-09-06
    • US11801694
    • 2007-05-10
    • Tetsuya ShirotaTakashi Yoneyama
    • Tetsuya ShirotaTakashi Yoneyama
    • G06K9/00
    • G02B21/367
    • An observation state obtainment unit obtains an observation state of a microscope at the time of obtaining the microscopic image of a specimen obtained by using the microscope. A motion image data generation unit generates data of a motion image from the microscopic images of a time series. A correlation addition unit adds, to data of the motion image, information that correlates microscopic images constituting the motion image with an observation state of the microscope at the time of obtaining the microscopic images. A record unit records data of the motion image and an observation state of the microscope correlated with the data.
    • 观察状态获取单元获得通过使用显微镜获得的样本的显微镜图像时的显微镜的观察状态。 运动图像数据生成单元从时间序列的显微镜图像生成运动图像的数据。 相关附加单元将运动图像的数据添加到将构成运动图像的显微图像与获得显微镜图像时的显微镜的观察状态相关联的信息。 记录单元记录运动图像的数据和与数据相关的显微镜的观察状态。
    • 30. 发明授权
    • Microscope apparatus and microscope system
    • 显微镜装置和显微镜系统
    • US07929738B2
    • 2011-04-19
    • US11545416
    • 2006-10-10
    • Tetsuya ShirotaYasuko IshiiTakashi Yoneyama
    • Tetsuya ShirotaYasuko IshiiTakashi Yoneyama
    • G06K9/00G02B21/00
    • G02B21/367G02B21/368
    • A microscope apparatus includes a capture unit for capturing a microscopic image of a specimen in a predetermined microscopy, a capture control unit controlling the capture unit and capturing a microscopic image about the same specimen with a plurality of predetermined resolutions, and a microscopy switch unit switching the microscopy. With the configuration, the capture control unit at least includes a first capture control unit allowing the capture unit to capture the specimen with a first resolution controlled in advance, a definition unit defining a plurality of small sections obtained by dividing a first microscopic image captured by the capture unit under control of the first capture control unit; and a second capture control unit allowing the capture unit to capture a portion corresponding to the small section of the specimen with a predetermined second resolution as a resolution higher than the first resolution.
    • 显微镜装置包括用于捕获预定显微镜中的样本的微观图像的捕获单元,捕获控制单元,其控制捕获单元并且以多个预定分辨率捕获关于相同样本的显微图像,以及显微镜切换单元切换 显微镜。 利用该配置,捕获控制单元至少包括第一捕获控制单元,其允许捕获单元以预先控制的第一分辨率捕获样本;界定单元,定义通过划分由第一微观图像捕获的第一微观图像而获得的多个小部分 所述捕获单元在所述第一捕获控制单元的控制下; 以及第二捕获控制单元,其允许捕获单元以预定的第二分辨率捕获与样本的小部分相对应的部分作为高于第一分辨率的分辨率。