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21. 发明申请

US20120153236A1 MANUFACTURING OF MULTIFUNCTIONAL ELECTRICALLY CONDUCTIVE/TRANSPARENT/FLEXIBLE FILMS 审中-公开
标题翻译：多功能电导/透明/柔性膜的制造
公开(公告)号：US20120153236A1
公开(公告)日：2012-06-21
申请号：US13383988
申请日：2010-07-15
申请人： Mukerrem Cakmak , Wei Zhao , Baris Yalcin
发明人： Mukerrem Cakmak , Wei Zhao , Baris Yalcin
IPC分类号： H01B1/12 , B29C47/08 , H01B1/04 , H01B1/02 , B82Y30/00
CPC分类号： B29C39/18 , B29D7/01 , B29K2105/162 , B29K2995/0005 , B32B5/02 , B32B5/08 , B32B27/12 , B32B27/281 , B32B27/308 , B32B27/325 , B32B27/365 , B32B27/40 , B32B33/00 , B32B2260/021 , B32B2260/046 , B32B2262/02 , B32B2262/12 , B32B2264/105 , B32B2307/202 , B32B2307/412 , B32B2307/546 , B32B2457/00 , D01D5/0084
摘要： The present invention relates to a method for producing flexible, stretchable transparent and highly electrically conducting hybrid polymer films comprising electrically conductive electrospun nanofibers embedded in solution cast dielectric polymer films. In one embodiment, the present invention utilizes an electrically conductive nanofiber, or nanofiber structure, that is embedded in a suitable polymer film. In one embodiment, the electrically conductive nanofiber, or nanofiber structure, can be electrospun from a suitable polymer solution that contains a suitable amount of, for example, at least one conductive material. In one embodiment, the flexible polymer film portion of the present invention can be formed from poly(methyl methacrylate) (PMMA) or polyimide. In another embodiment, the present invention relates to flexible polymer films that have conductive structures embedded therein, wherein the flexible polymer film portion is form via a casting process to produce transparent films from, for example, polycarbonate, polyurethane and/or cyclopolyolefin polymer compositions.
摘要翻译：本发明涉及一种用于制造柔性，可拉伸的透明和高导电性杂化聚合物膜的方法，其包括嵌入溶液流延电介质聚合物膜中的导电电纺丝纳米纤维。在一个实施方案中，本发明使用嵌入合适的聚合物膜中的导电纳米纤维或纳米纤维结构。在一个实施方案中，导电纳米纤维或纳米纤维结构可以从包含适量的例如至少一种导电材料的合适的聚合物溶液静电纺丝。在一个实施方案中，本发明的柔性聚合物膜部分可以由聚（甲基丙烯酸甲酯）（PMMA）或聚酰亚胺形成。在另一个实施方案中，本发明涉及具有嵌入其中的导电结构的柔性聚合物膜，其中柔性聚合物膜部分通过流延法形成，以从例如聚碳酸酯，聚氨酯和/或环烯烃聚合物组合物制备透明膜。

22. 发明授权

US08202857B2 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase 1 有权
标题翻译： 11-羟基类固醇脱氢酶1的1,3-氧杂氮杂环庚烷-2-酮和1,3-二氮杂环庚烷-2-酮抑制剂
公开(公告)号：US08202857B2
公开(公告)日：2012-06-19
申请号：US12583009
申请日：2009-08-11
申请人： David A. Claremon , Linghang Zhuang , Colin M. Tice , Suresh B. Singh , Yuanjie Ye , Wei Zhao , Katerina Leftheris
发明人： David A. Claremon , Linghang Zhuang , Colin M. Tice , Suresh B. Singh , Yuanjie Ye , Wei Zhao , Katerina Leftheris
IPC分类号： C07D265/10 , C07D413/04 , C07D413/06 , C07D413/10 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/10 , C07D417/14 , A61K31/55 , A61K31/553 , A61P3/06
CPC分类号： C07D243/04 , C07D401/04 , C07D401/10 , C07D403/04 , C07D403/10 , C07D409/10
摘要： This invention relates to novel compounds of the Formula (I), (I*), (I**), I, Ia, Ib, Ic, Id, Ie, If, Ig, Il1-3, Im1-3, In1-3, or Io1-2, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.
摘要翻译：本发明涉及式（I），（I *），（I **），I，Ia，Ib，Ic，Id，Ie，If，Ig，Il1-3，Im1-3， 3或Io1-2，其药学上可接受的盐及其药物组合物，其可用于治疗与哺乳动物中11β-HSD1的调节或抑制相关的疾病的治疗。本发明进一步涉及新化合物的药物组合物及其用于减少或控制细胞中皮质醇产生或抑制细胞中可的松转化为皮质醇的方法。

23. 发明授权

US08106221B2 Renin inhibitors 失效
标题翻译：肾素抑制剂
公开(公告)号：US08106221B2
公开(公告)日：2012-01-31
申请号：US12665219
申请日：2008-06-20
申请人： John J. Baldwin , Salvacion Cacatian , David A. Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Alexey V. Ishchenko , Lanqi Jia , Gerard McGeehan , Robert D. Simpson , Suresh B. Singh , Colin M. Tice , Zhenrong Xu , Jing Yuan , Wei Zhao , Linghang Zhuang
发明人： John J. Baldwin , Salvacion Cacatian , David A. Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Alexey V. Ishchenko , Lanqi Jia , Gerard McGeehan , Robert D. Simpson , Suresh B. Singh , Colin M. Tice , Zhenrong Xu , Jing Yuan , Wei Zhao , Linghang Zhuang
IPC分类号： C07D325/00 , C07D315/00 , C07D493/00 , C07C275/04 , A61K31/351 , A61K31/17 , A01N47/28
CPC分类号： C07C275/24 , C07C275/14 , C07C275/16 , C07C2601/14 , C07C2603/74 , C07D209/46 , C07D309/04 , C07D311/96 , C07D313/04
摘要： The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.
摘要翻译：本发明涉及天冬氨酸蛋白酶抑制剂。本发明还涉及包含所公开的天冬氨酸蛋白酶抑制剂的药物组合物。本发明还涉及在有需要的受试者中拮抗一种或多种天冬氨酸蛋白酶的方法，以及使用所公开的天冬氨酸蛋白酶抑制剂治疗受试者中天冬氨酸蛋白酶介导的病症的方法。

24. 发明申请

US20110263584A1 Cyclic Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase 1 有权
标题翻译： 11β-羟基类固醇脱氢酶的循环抑制剂1
公开(公告)号：US20110263584A1
公开(公告)日：2011-10-27
申请号：US12990306
申请日：2009-04-30
申请人： David A. Claremon , Linghang Zhuang , Katerina Leftheris , Colin M. Tice , Zhenrong Xu , Yuanjie Ye , Suresh B. Singh , Salvacion Cacatian , Frank Himmelsback , Matthias Eckhardt , Wei Zhao
发明人： David A. Claremon , Linghang Zhuang , Katerina Leftheris , Colin M. Tice , Zhenrong Xu , Yuanjie Ye , Suresh B. Singh , Salvacion Cacatian , Frank Himmelsback , Matthias Eckhardt , Wei Zhao
IPC分类号： A61K31/5355 , C07D413/14 , A61P43/00 , C07D413/10
CPC分类号： C07D413/10 , C07D413/14 , C07D417/10 , C07D417/14
摘要： This invention relates to novel compounds of the Formula I, Ik, Iq1-21, Ir1-21, Is1-21, It1-7, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.
摘要翻译：本发明涉及式I，Ik，Iq1-21，Ir1-21，Is1-21，It1-7，其药学上可接受的盐及其药物组合物的新型化合物，其可用于治疗与在哺乳动物中调节或抑制11＆bgr-HSD1。本发明进一步涉及新化合物的药物组合物及其用于减少或控制细胞中皮质醇产生或抑制细胞中可的松转化为皮质醇的方法。

25. 发明申请

US20110207485A1 User Equipment, Radio Base Station and Methods Therein 有权
标题翻译：用户设备，无线基站及其方法
公开(公告)号：US20110207485A1
公开(公告)日：2011-08-25
申请号：US12977875
申请日：2010-12-23
申请人： Konstantinos Dimou , Magnus Lindström , Wei Zhao
发明人： Konstantinos Dimou , Magnus Lindström , Wei Zhao
IPC分类号： H04B7/24
CPC分类号： H04W36/0055
摘要： Embodiments herein relate to a method in a user equipment for handling a radio link failure in a radio communications network. The user equipment is served in a first cell controlled by a radio base station. The radio base station is comprised in the radio communications network, The user equipment detects a first indication of a failure of a radio link between the user equipment and the radio base station. The user equipment then transmits a second indication of radio link failure to the radio base station when the first indication is detected.
摘要翻译：本文的实施例涉及用于处理无线电通信网络中的无线电链路故障的用户设备中的方法。用户设备在由无线电基站控制的第一小区中服务。无线基站包括在无线通信网络中，用户设备检测用户设备和无线基站之间的无线链路的故障的第一指示。然后，当检测到第一指示时，用户设备向无线电基站发送无线电链路故障的第二指示。

26. 发明申请

US20110139497A1 Via Structure Integrated in Electronic Substrate 有权
标题翻译：电子基板集成电路结构
公开(公告)号：US20110139497A1
公开(公告)日：2011-06-16
申请号：US12637104
申请日：2009-12-14
申请人： Xia Li , Wei Zhao , Yu Cao , Shiqun Gu , Seung H. Kang , Ming-Chu King
发明人： Xia Li , Wei Zhao , Yu Cao , Shiqun Gu , Seung H. Kang , Ming-Chu King
IPC分类号： H05K1/09 , B05D5/12 , H01R13/648 , H01R43/00
CPC分类号： H01L23/552 , H01L23/14 , H01L23/49827 , H01L23/645 , H01L23/66 , H01L2223/6616 , H01L2223/6622 , H01L2223/6638 , H01L2924/0002 , H01L2924/3011 , H05K1/0222 , H05K1/0245 , H05K3/4602 , H05K3/4644 , H05K2201/09809 , Y10T29/49117 , H01L2924/00
摘要： A system of via structures disposed in a substrate. The system includes a first via structure that comprises an outer conductive layer, an inner insulating layer, and an inner conductive layer disposed in the substrate. The outer conductive layer separates the inner insulating layer and the substrate and the inner insulating layer separates the inner conductive layer and the outer conductive layer. A first signal of a first complementary pair passes through the inner conductive layer and a second signal of the first complementary pair passes through the outer conductive layer. In different embodiments, a method of forming a via structure in an electronic substrate is provided.
摘要翻译：设置在基板中的通孔结构的系统。该系统包括第一通孔结构，其包括外导电层，内绝缘层和设置在基板中的内导电层。外部导电层分离内部绝缘层和基板，内部绝缘层分离内部导电层和外部导电层。第一互补对的第一信号通过内导电层，第一互补对的第二信号通过外导电层。在不同的实施例中，提供了一种在电子衬底中形成通孔结构的方法。

27. 发明申请

US20110105506A1 Diaminoalkane aspartic protease inhibitors 失效
标题翻译：二氨基烷烃天冬氨酸蛋白酶抑制剂
公开(公告)号：US20110105506A1
公开(公告)日：2011-05-05
申请号：US12802142
申请日：2010-05-28
申请人： John J. Baldwin , David A. Claremon , Colin M. Tice , Salvacion Cacatian , Lawrence W. Dillard , Alexey V. Ishchenko , Jing Yuan , Zhenrong Xu , Gerard McGeehan , Wei Zhao , Robert D. Simpson , Suresh B. Singh , Patrick T. Flaherty , Jean-Pierre Wery
发明人： John J. Baldwin , David A. Claremon , Colin M. Tice , Salvacion Cacatian , Lawrence W. Dillard , Alexey V. Ishchenko , Jing Yuan , Zhenrong Xu , Gerard McGeehan , Wei Zhao , Robert D. Simpson , Suresh B. Singh , Patrick T. Flaherty , Jean-Pierre Wery
IPC分类号： A61K31/5375 , C07D211/22 , C07D417/04 , C07D405/10 , C07D211/60 , A61K31/451 , A61K31/445 , A61K31/454 , A61K31/4525 , C07D265/30
CPC分类号： C07D417/06 , C07C233/40 , C07C235/40 , C07C235/42 , C07C271/20 , C07C2601/08 , C07C2601/14 , C07C2603/74 , C07D211/22 , C07D211/56 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/06 , C07F7/081 , C07F7/0812
摘要： Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.
摘要翻译：已经发现式I的二氨基烷烃是口服活性的并且结合天冬氨酸蛋白酶以抑制它们的活性。它们可用于治疗或改善与升高的天冬氨酸蛋白酶活性水平相关的疾病。本发明还涉及在有需要的受试者中使用式I化合物来改善或治疗天冬氨酸蛋白酶相关病症的方法，包括向所述受试者施用有效量的式I化合物。

28. 发明申请

US20110067073A1 COMMUNICATION UNIT AND A METHOD FOR PROVIDING ACCESS TO AN IPTV NETWORK 审中-公开
标题翻译：通信单元和提供对IPTV网络的访问的方法
公开(公告)号：US20110067073A1
公开(公告)日：2011-03-17
申请号：US12812700
申请日：2008-01-22
申请人： Johan Kölhi , Wei Zhao
发明人： Johan Kölhi , Wei Zhao
IPC分类号： H04N7/18
CPC分类号： H04N21/64322 , H04L65/4076 , H04N21/6175 , H04N21/632
摘要： The present invention is arranged to provide an improved way of remote access to locally transmitted multicast television channels. The invention relates to a communication unit for communication of IPTV channels to at least one user unit. It comprises a receiver arranged to receive a set of IPTV channels, and a distribution channel set up unit arranged to set up one separate distribution channel to each user unit so as to distribute one of the IPTV channels in said set of IPTV channels over each distribution channel. The present invention further relates to a method for providing remote access to a first IPTV network.
摘要翻译：本发明被设置为提供远程访问本地发送的多播电视频道的改进方式。本发明涉及一种用于将IPTV频道通信至少一个用户单元的通信单元。它包括接收一组IPTV信道的接收机和分配信道建立单元，该分配信道建立单元设置成为每个用户单元建立一个单独的分发信道，以便在每个分配的所述IPTV信道集中分配一个IPTV信道渠道。本发明还涉及一种用于提供对第一IPTV网络的远程访问的方法。

29. 发明申请

US20100280005A1 Renin Inhibitors 审中-公开
标题翻译：肾素抑制剂
公开(公告)号：US20100280005A1
公开(公告)日：2010-11-04
申请号：US12450620
申请日：2008-04-04
申请人： Jonh J. Baldwin , Salvacion Cacatian , David Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Bahman Ghavimi-Alagha , John Gleason , Alexey V. Ishchenko , Brian Lawhorn , Gerard McGeehan , Jaclyn R. Patterson , Simon F. Semus , Robert D. Simpson , Suresh B. Singh , Colin Tice , Tritin Tran , Zhenrong Xu , Jing Yuan , Wei Zhao
发明人： Jonh J. Baldwin , Salvacion Cacatian , David Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Bahman Ghavimi-Alagha , John Gleason , Alexey V. Ishchenko , Brian Lawhorn , Gerard McGeehan , Jaclyn R. Patterson , Simon F. Semus , Robert D. Simpson , Suresh B. Singh , Colin Tice , Tritin Tran , Zhenrong Xu , Jing Yuan , Wei Zhao
IPC分类号： A61K31/445 , C07D211/60 , C07D401/02 , C07D413/02 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K31/58 , A61P9/12
CPC分类号： C07D211/22 , C07D401/06
摘要： Disclosed are compounds of Formula I, wherein the R, R1, R2, R3, X, Y, A, Q, E, and G are defined herein. These compounds bind to aspartic proteases to inhibit their activity and are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also disclosed are methods of use of the compounds of Formula I for ameliorating or treating aspartic protease related disorders in a subject in need thereof.
摘要翻译：公开了式I的化合物，其中R，R 1，R 2，R 3，X，Y，A，Q，E和G如本文所定义。这些化合物与天冬氨酸蛋白酶结合以抑制其活性，并且可用于治疗或改善与天冬氨酸蛋白酶活性相关的疾病。还公开了使用式I化合物在有需要的受试者中改善或治疗天冬氨酸蛋白酶相关病症的方法。

30. 发明申请

US20100208595A1 ARRANGEMENT AND A METHOD FOR HANDLING FAILURES IN A NETWORK 有权
标题翻译：安排和处理网络故障的方法
公开(公告)号：US20100208595A1
公开(公告)日：2010-08-19
申请号：US12682470
申请日：2007-10-09
申请人： Wei Zhao , Johan Kölhi
发明人： Wei Zhao , Johan Kölhi
IPC分类号： H04L12/24
CPC分类号： H04L41/0672 , H04L41/0213 , H04L41/0659 , H04L41/0677 , H04L43/0811 , H04L43/10 , H04L45/26 , H04L45/66 , H04L69/40
摘要： The present invention relates to an arrangement comprising an Ethernet carrier network, managed by a management system (100) and comprising a number of levels of management domains, each comprising a number of edge nodes (10, 20, 30, 40) and a number of intermediate nodes (1, 2, 3, 4, 5, 6, 7, 8). Each edge node (10, 20, 30, 40) comprises fault detection of connectivity check messages and fault locating means with holding means (11, 21, 31, 41) adapted to hold path information for the paths to all other edge nodes. A fault detection means of an edge node having detected a fault is adapted to activate edge node fault locating means to locate the fault using the patch information in the edge node holding means to find a first target intermediate node substantially in the middle of the path containing the fault, and to, directly, send a first loop back message to said intermediate node. A response from said intermediate node indicates that the fault is located at the distant portion of the path, no response indicates that the fault is located at the proximate portion of the path. Further loop back messages are sent to consecutively identified intermediate nodes of the respective path portion identified to contain the fault by the respective preceding loop back message until the fault is localized.
摘要翻译：本发明涉及一种包括由管理系统（100）管理并且包括多个级别的管理域的以太网运营商网络的装置，每个管理域包括多个边缘节点（10,20,30,40）和数量的中间节点（1，2，3，4，5，6，7，8）。每个边缘节点（10,20,30,40）包括连接性检查消息的故障检测和具有适于保持用于所有其他边缘节点的路径的路径信息的保持装置（11,21,31,41）的故障定位装置。已经检测到故障的边缘节点的故障检测装置适于激活边缘节点故障定位装置，以使用边缘节点保持装置中的补丁信息来定位故障，以在第故障，并且直接向所述中间节点发送第一循环消息。来自所述中间节点的响应指示故障位于路径的远处，没有响应指示故障位于路径的最近部分。进一步的循环消息被发送到被识别为通过相应的先前循环消息识别为包含故障的相应路径部分的连续标识的中间节点，直到故障被定位为止。

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