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21. 发明申请

US20100076079A1 Pharmaceutical Compositions Of Short-Acting Sedative Hypnotic Agent 失效
标题翻译：短效镇静催眠剂的药物组合物
公开(公告)号：US20100076079A1
公开(公告)日：2010-03-25
申请号：US12629134
申请日：2009-12-02
申请人： Thomas E. Jenkins , Jennifer Bolton
发明人： Thomas E. Jenkins , Jennifer Bolton
IPC分类号： A61K31/24 , A61P25/20
CPC分类号： A61K9/1075 , A61K31/20 , A61K31/216 , A61K31/325 , Y10S514/816 , Y10S514/937
摘要： The invention provides pharmaceutical compositions comprising a phenylacetic acid ester compound useful for inducing or maintaining general anesthesia or sedation in mammals, methods for preparing such compositions, and methods for inducing or maintaining anesthesia or sedation using such compositions.
摘要翻译：本发明提供药物组合物，其包含用于诱导或维持哺乳动物全身麻醉或镇静的苯乙酸酯化合物，制备该组合物的方法，以及使用这些组合物诱导或维持麻醉或镇静的方法。

22. 发明授权

US07514425B2 Short-acting sedative hypnotic agents for anesthesia and sedation 失效
标题翻译：用于麻醉和镇静的短效镇静催眠药
公开(公告)号：US07514425B2
公开(公告)日：2009-04-07
申请号：US11332409
申请日：2006-01-13
申请人： Thomas E. Jenkins , Sabine Axt , Jennifer Bolton
发明人： Thomas E. Jenkins , Sabine Axt , Jennifer Bolton
IPC分类号： A61K31/55
CPC分类号： A61K31/24 , A61K31/216 , C07C69/734 , C07C235/20
摘要： The invention provides compounds compositions and methods useful for inducing or maintaining general anesthesia or sedation in mammals.
摘要翻译：本发明提供了可用于诱导或维持哺乳动物全身麻醉或镇静的化合物组合物和方法。

23. 发明授权

US07449113B2 Controlling wastewater treatment processes 有权
标题翻译：控制废水处理工艺
公开(公告)号：US07449113B2
公开(公告)日：2008-11-11
申请号：US10667893
申请日：2003-09-23
申请人： Thomas E. Jenkins , David T. Redmon , Timothy D. Hilgart , Juan de Dios Trillo Monsoriu , Ian Trillo Fox
发明人： Thomas E. Jenkins , David T. Redmon , Timothy D. Hilgart , Juan de Dios Trillo Monsoriu , Ian Trillo Fox
IPC分类号： C02F3/00
CPC分类号： C02F3/006 , C02F2209/22 , C02F2209/225 , C02F2209/38 , Y02W10/15
摘要： Methods and apparatus for continuing, automated control of wastewater treatment processes. In certain preferred embodiments, method and apparatus for control of aeration in suspended growth biological treatment processes, especially in activated sludge processes.
摘要翻译：污水处理过程的持续自动化控制的方法和设备。在某些优选实施方案中，用于控制悬浮生长生物处理过程中曝气的方法和装置，特别是在活性污泥方法中。

24. 发明授权

US07101909B2 Calcium channel drugs and uses 有权
标题翻译：钙通道药物及用途
公开(公告)号：US07101909B2
公开(公告)日：2006-09-05
申请号：US10877368
申请日：2004-06-25
申请人： Yu-Hua Ji , Maya Natarajan , John H. Griffin , Thomas E. Jenkins
发明人： Yu-Hua Ji , Maya Natarajan , John H. Griffin , Thomas E. Jenkins
IPC分类号： A61K31/235
CPC分类号： A61K47/55 , A61K47/545
摘要： Novel multibinding compounds are disclosed. The compounds of this invention comprise 2–10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Ca++ channel, thereby modulating the biological activities thereof.
摘要翻译：公开了新颖的多键合化合物。本发明的化合物包含共价连接的2-10配体，每个配体能够结合到Ca ++通道中的配体结合位点，从而调节其生物活性。

25. 发明授权

US06897305B2 Calcium channel drugs and uses 有权
标题翻译：钙通道药物及用途
公开(公告)号：US06897305B2
公开(公告)日：2005-05-24
申请号：US09456429
申请日：1999-12-08
申请人： Yu-Hua Ji , Maya Natarajan , John H. Griffin , Thomas E. Jenkins
发明人： Yu-Hua Ji , Maya Natarajan , John H. Griffin , Thomas E. Jenkins
IPC分类号： A61K47/48 , G01N33/68 , C07D515/02 , C07D231/56 , C07D279/16 , G01N33/53
CPC分类号： G01N33/6872 , A61K47/545 , A61K47/55 , A61K47/65 , G01N2500/04
摘要： Novel multibinding compounds are disclosed. The compounds of this invention comprise 2-10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Ca++ channel , thereby modulating the biological activities thereof.
摘要翻译：公开了新颖的多键合化合物。本发明的化合物包含共价连接的2-10配体，每个配体能够结合到Ca ++通道中的配体结合位点，从而调节其生物活性。

26. 发明授权

US5900371A Metal complexed serine protease inhibitors 失效
公开(公告)号：US5900371A
公开(公告)日：1999-05-04
申请号：US925844
申请日：1997-09-08
申请人： James M. Clark , Thomas E. Jenkins , Bradley A. Katz , Robert M. Stroud
发明人： James M. Clark , Thomas E. Jenkins , Bradley A. Katz , Robert M. Stroud
IPC分类号： C07K14/81 , C12N9/64 , C12N9/76 , C12N9/99 , C12N11/08
CPC分类号： C12N9/6424 , C07K14/811
摘要： Serine protease inhibitors are provided comprising compounds having a P site binding moiety and a divalent cation(s) chelating moiety which are pre-prepared as divalent cation(s) complexes or combined with the serine protease in the presence of divalent cation(s). The compounds are shown to have high inhibitory activity when complexed to divalent cation(s) and find use in various processes associated with serine protease isolation and inhibition.

27. 发明授权

US5693515A Metal complexed serine protease inhibitors 失效
标题翻译：金属络合丝氨酸蛋白酶抑制剂
公开(公告)号：US5693515A
公开(公告)日：1997-12-02
申请号：US430742
申请日：1995-04-28
申请人： James M. Clark , Thomas E. Jenkins , Bradley A. Katz , Robert M. Stroud
发明人： James M. Clark , Thomas E. Jenkins , Bradley A. Katz , Robert M. Stroud
IPC分类号： C07K14/81 , C12N9/64 , C12N9/99 , C12N9/76 , C12N11/08
CPC分类号： C12N9/6424 , C07K14/811
摘要： Serine protease inhibitors are provided comprising compounds having a P site binding moiety and a divalent cation(s) chelating moiety which are pre-prepared as divalent cation(s) complexes or combined with the serine protease in the presence of divalent cation(s). The compounds are shown to have high inhibitory activity when complexed to divalent cation(s) and find use in various processes associated with serine protease isolation and inhibition.
摘要翻译：提供丝氨酸蛋白酶抑制剂，其包含具有P位结合部分和二价阳离子螯合部分的化合物，其在二价阳离子存在下预先制备为二价阳离子配合物或与丝氨酸蛋白酶组合。当与二价阳离子络合时，这些化合物被证明具有高的抑制活性，可用于与丝氨酸蛋白酶分离和抑制相关的各种过程。

28. 发明授权

US5542845A Dental syringe safety sheath with modified duckbill valve 失效
标题翻译：带修改鸭嘴阀的牙科注射器安全护套
公开(公告)号：US5542845A
公开(公告)日：1996-08-06
申请号：US289303
申请日：1994-08-11
申请人： Thomas E. Jenkins
发明人： Thomas E. Jenkins
IPC分类号： A61C1/16 , F16K15/14
CPC分类号： F16K15/147 , A61C1/16
摘要： A dental syringe safety sheath having a modified duckbill valve for minimizing cross-contamination between dental patients is provided. The sheath includes a generally tubular body member having a nozzle engaging portion and a discharge portion. The nozzle engaging portion is configured to substantially fit over and cover the nozzle of a dental syringe having a discharge orifice. The discharge portion defines a fluid passageway having an inlet adjacent the discharge orifice and outlet downstream therefrom. The fluid passageway progressively narrows in cross-section between the inlet and the outlet to form a substantially wedge-shaped cavity terminating in a slit disposed between a pair of opposing sealing lips. The cross-section of the sealing lips between the ends of the slit is wider than the corresponding cross-section of the sealing lips at the lip margins. As an additional or alternative feature of the present invention, the collective width of the sealing lips measured along a discrete portion of the lips between the ends of the slit being at least as great as the length of the lips measured along the slit.
摘要翻译：提供了一种具有改进的鸭嘴阀的牙科注射器安全护套，用于使牙齿患者之间的交叉污染最小化。护套包括具有喷嘴接合部分和排出部分的大致管状本体构件。喷嘴接合部被配置为基本上配合并覆盖具有排放孔的牙科注射器的喷嘴。排出部分限定了一个流体通道，该流体通道具有邻近排出孔的入口和在其下游的出口。流体通道在入口和出口之间的横截面逐渐变窄，以形成终止于设置在一对相对的密封唇之间的狭缝中的大致楔形的空腔。狭缝的端部之间的密封唇的横截面比唇缘处的密封唇的相应横截面宽。作为本发明的附加或替代特征，沿着狭缝的端部之间的唇缘的离散部分测量的密封唇的总体宽度至少与沿着狭缝测量的唇的长度一样大。

29. 发明授权

US5487239A Refrigerator gasket assembly 失效
标题翻译：冰箱垫片组件
公开(公告)号：US5487239A
公开(公告)日：1996-01-30
申请号：US254396
申请日：1994-06-06
申请人： Thomas E. Jenkins , Charles R. Mulligan , Duane Jubenville
发明人： Thomas E. Jenkins , Charles R. Mulligan , Duane Jubenville
IPC分类号： F25D23/08 , E06B7/22
CPC分类号： F25D23/087
摘要： A refrigerator has a cabinet with an outer case and an inner liner. The liner forms a storage compartment with an access opening. A cabinet face portion surrounds the opening and a door selectively closes the compartment. The door includes a flange which overlaps the face portion and a gasket mounted on the flange engages face portion. The gasket is an elongated body of a co-extruded material and includes a base wall of a rigid material mounted on the door frame, a contact wall spaced from the base wall for sealing engagement with the face portion and a pair of side walls connecting the base and contact walls to form a hollow interior. The contact wall includes a pair of spaced apart elongated strips of more rigid material connected by an elongated strip of less rigid material. The less rigid strip has an elongated outward projecting bow shape. The side walls are indented in a "V" shape and the apex of the V has a reduced thickness. A strip of fiber glass, with a net like backing on one side, is in the interior of the gasket.
摘要翻译：冰箱具有外壳和内衬的柜体。衬垫形成具有进入开口的储藏室。橱柜面部分围绕开口并且门选择性地关闭隔间。门包括与面部重叠的凸缘和安装在凸缘上的垫圈接合面部。垫圈是共挤出材料的细长主体，并且包括安装在门框上的刚性材料的底壁，与底壁间隔开的用于与面部密封接合的接触壁和一对侧壁，基部和接触壁以形成中空的内部。接触壁包括一对具有更刚性材料的间隔开的细长条，其通过较不刚性材料的细长带连接。较不牢固的条带具有伸长的向外突出的弓形。侧壁以“V”形缩进，并且V的顶点具有减小的厚度。在一侧具有网状背衬的玻璃纤维条在垫圈的内部。

30. 发明授权

US4535524A Method of assembling a rack-supporting channel and stop 失效
标题翻译：组装支架通道并停止的方法
公开(公告)号：US4535524A
公开(公告)日：1985-08-20
申请号：US563278
申请日：1984-01-30
申请人： Thomas E. Jenkins
发明人： Thomas E. Jenkins
IPC分类号： A47B88/14 , A47L15/50 , B23P11/02
CPC分类号： A47L15/507 , A47B88/14 , A47B2210/0043 , A47B2210/0059 , A47B2210/04 , Y10T29/49876
摘要： A channel and stop arrangement for structures of the type containing racks or drawers supported from sliding or rolling support members carried in a channel, comprising an elongated channel member of generally C-shaped cross section adapted to receive the support members in its interior trackway and a stop member positioned in the end of the channel member to retain the support members in the trackway. The stop member comprises a cap portion of enlarged cross section joined to a rigid central body portion by a neck portion of reduced cross section and a lateral positioning tab extending from the central body portion. The tab is adapted to flex longitudinally relative to the central body portion between a normal position and an assembly position to facilitate insertion of the stop member into the channel and to rigidly oppose lateral motion relative to the central body portion to laterally retain the stop member in the channel. The channel member side wall has an indented portion formed near its front-facing end rigidly projecting into the trackway. When the stop is positioned in the channel, the indented portion extends between the cap portion and the central body portion to prevent longitudinal outward movement of the stop member, the indented portion and the central body portion providing sufficient structural rigidity to oppose longitudinal loads applied to the stop member by pull-out forces exerted on the rack or drawer.
摘要翻译：一种用于包含由在通道中承载的滑动或滚动支撑构件支撑的搁架或抽屉的类型的结构的通道和停止装置，包括适于在其内部轨道中接收支撑构件的大致C形横截面的细长通道构件，以及定位在通道构件的末端以将支撑构件保持在轨道中。止动构件包括通过减小横截面的颈部连接到刚性中心体部分的放大横截面的帽部分和从中心主体部分延伸的横向定位凸片。突片适于在正常位置和组装位置之间相对于中心主体部分纵向弯曲，以有助于将止动构件插入通道并且刚性地相对于中心主体部分的横向运动以将止动构件横向保持在这个频道。通道构件侧壁具有在其刚性地突出到轨道中的前后端附近形成的凹入部。当止动件定位在通道中时，凹口部分在帽部分和中心主体部分之间延伸，以防止止动构件，凹入部分和中心体部分的纵向向外移动提供足够的结构刚度以抵抗施加到停止构件通过施加在机架或抽屉上的拉出力。

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