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21. 发明授权

US08680161B2 Compositions of fat-soluble active ingredients containing gum ghatti 有权
标题翻译：含有胶原糖的脂溶性活性成分的组合物
公开(公告)号：US08680161B2
公开(公告)日：2014-03-25
申请号：US12995836
申请日：2009-06-03
申请人： Andrea Hitzfeld , Bruno H. Leuenberger , Olivia Vidoni
发明人： Andrea Hitzfeld , Bruno H. Leuenberger , Olivia Vidoni
IPC分类号： A61K31/07 , A23L1/303
CPC分类号： A23L2/52 , A23K20/158 , A23K20/174 , A23K20/179 , A23K50/75 , A23K50/80 , A23L5/44 , A23L29/25 , A23L29/35 , A23L33/105 , A23L33/155 , A23V2002/00 , A23V2250/5056 , A23V2200/044
摘要： The present invention relates to compositions containing plant gums and one or more fat-soluble active ingredients, wherein the composition comprises less than 40 weight-% oil, based on the total composition in dry matter. These compositions can be used for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions. The present invention also refers to the preparation of such compositions. The present invention furthermore refers to a process for the manufacture of a beverage by mixing the compositions with ingredients of beverages. The present invention also refers to beverages obtainable by this process.
摘要翻译：本发明涉及含有植物胶和一种或多种脂溶性活性成分的组合物，其中所述组合物包含小于40重量％的油，基于干物质的总组成。这些组合物可用于食品饮料，动物饲料，化妆品或药物组合物的富集，强化和/或着色。本发明还涉及这种组合物的制备。本发明还涉及通过将组合物与饮料成分混合来制造饮料的方法。本发明还涉及可通过该方法获得的饮料。

22. 发明申请

US20110052707A1 COMBINATION OF VITAMIN D AND 25-HYDROXYVITAMIN D 3 审中-公开
标题翻译：维生素D和25-羟基维生素D 3的组合
公开(公告)号：US20110052707A1
公开(公告)日：2011-03-03
申请号：US12867372
申请日：2008-02-12
申请人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elisabeth Stoecklin , Kai Urban , Swen Wolfram
发明人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elisabeth Stoecklin , Kai Urban , Swen Wolfram
IPC分类号： A61K31/047 , A61K9/50 , C07C33/14 , A61P3/02 , A61P1/16
CPC分类号： A61K9/1694 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K31/047 , A61K31/593 , A61K45/06 , A61K47/14 , C07C401/00 , A61K2300/00
摘要： We disclose compositions comprising Vitamin D (cholecalciferol and/or ergocalciferol) and 25-OH D3 (calcifediol), and use of those compositions to affect at least concentration, bioavailability, metabolism, or efficacy of vitamin D in a human. Forms and dosages of the composition, as well as processes for manufacturing a spray-dried formulation, are also disclosed.
摘要翻译：我们公开了包含维生素D（胆钙化甾醇和/或麦角钙化醇）和25-OH D3（calcifediol）的组合物，以及使用这些组合物至少影响维生素D在人体中的至少浓度，生物利用度，代谢或功效。还公开了组合物的形式和剂量，以及用于制造喷雾干燥制剂的方法。

23. 发明申请

US20090258954A1 PROTECTIVE HYDROCOLLOID FOR ACTIVE INGREDIENTS 审中-公开
标题翻译：活性成分的保护性水解剂
公开(公告)号：US20090258954A1
公开(公告)日：2009-10-15
申请号：US12095927
申请日：2006-12-08
申请人： Markus Beck , Navagnana S. Hettiarachchy , Bruno H. Leuenberger , IIankovan Paraman , Christian Schaefer , Gerhard Wagner
发明人： Markus Beck , Navagnana S. Hettiarachchy , Bruno H. Leuenberger , IIankovan Paraman , Christian Schaefer , Gerhard Wagner
IPC分类号： A61K47/42 , A23K1/00 , C12P21/06
CPC分类号： C07K14/415 , A23J1/12 , A23J3/14 , A23J3/34 , A23K20/174 , A23K20/179 , A23K40/00 , A23L5/44 , A23L7/115 , A23L7/198 , A23L33/155 , A23P10/40 , A61K47/42 , C12P21/06 , C12Y304/00
摘要： (Modified) rice endosperm protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) rice endosperm protein and at least one active ingredient and to their manufacture, as well as to the (modified) rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) rice endosperm protein and such a composition, respectively.
摘要翻译：（改良型）水稻胚乳蛋白用作活性成分，特别是脂溶性活性成分和/或着色剂的新型保护性水胶体。包括包含（修饰的）水稻胚乳蛋白质和至少一种活性成分及其制备的组合物以及（修饰的）水稻胚乳蛋白质本身及其制造的组合物。这些组合物用于食品，饮料，动物饲料，个人护理或药物组合物的富集，强化和/或着色，以及含有这种（修饰的）水稻胚乳蛋白质的食品，饮料，动物饲料，个人护理和药物组合物和这样的组合物。

24. 发明申请

US20080193575A1 Compositions Containing Polysaccharides 有权
标题翻译：含多糖的组合物
公开(公告)号：US20080193575A1
公开(公告)日：2008-08-14
申请号：US11884433
申请日：2006-02-14
申请人： Chyi-Cheng Chen , Bruno H. Leuenberger
发明人： Chyi-Cheng Chen , Bruno H. Leuenberger
IPC分类号： A61K31/352 , A61K36/48
CPC分类号： A61K31/352 , A61K9/1652 , A61K36/48
摘要： The present invention relates to compositions, preferably in the form of a powder and/or granules, which contain as principal components a first component selected from the group consisting of isoflavones, soy products containing at least one isoflavone, and mixtures thereof, together with a polysaccharide as second component. A preferred first component is genistein or a pharmaceutically acceptable salt or derivative thereof (e.g. genistin). A preferred second component is pectin. The present invention further relates to a process for the manufacture of such compositions, and their use in dietary supplements, pharmaceutical and personal care compositions. The present invention is also directed to the use of a polysaccharide for improving the flowability of a component selected from the group consisting of isoflavones, soy products, preferably those containing at least one isoflavone, and mixtures thereof.
摘要翻译：本发明涉及组合物，优选以粉末和/或颗粒的形式，其以主要组分的形式含有选自异黄酮，含有至少一种异黄酮的大豆制品及其混合物的第一组分，以及一种多糖作为第二成分。优选的第一组分是染料木黄酮或其药学上可接受的盐或衍生物（例如染料木黄酮）。优选的第二组分是果胶。本发明还涉及制备这种组合物的方法及其在膳食补充剂，药物和个人护理组合物中的用途。本发明还涉及多糖用于改善选自异黄酮，大豆制品，优选含有至少一种异黄酮的组分的组分的流动性及其混合物的流动性的用途。

25. 发明申请

US20130281550A1 CAROTENOID COMPOSITIONS CONTAINING OCTENYL SUCCINATE ANHYDRIDE-MODIFIED GUM ACACIA 审中-公开
标题翻译：含有OCTENYL SUCCINATE ANHYDRIDE改性GAC ACACIA的CAROTENOID组合物
公开(公告)号：US20130281550A1
公开(公告)日：2013-10-24
申请号：US13883119
申请日：2011-10-04
申请人： Andrea Hitzfeld , Bruno H. Leuenberger , Olivia Vidoni
发明人： Andrea Hitzfeld , Bruno H. Leuenberger , Olivia Vidoni
IPC分类号： A23L2/58 , A61K47/06 , A61K8/31 , A61K47/36 , A61K8/73
CPC分类号： A61K8/73 , A23L2/52 , A23L2/58 , A23L5/44 , A23L29/25 , A23L33/10 , A23L35/10 , A23V2002/00 , A61K8/31 , A61K8/97 , A61K47/06 , A61K47/36 , A61K2800/10 , A61K2800/42 , A61K2800/92 , A61Q19/00 , A23V2250/5022 , A23V2250/211
摘要： The present invention relates to compositions comprising octenyl-succinic anhydride-modified gum acacia and carotenoids. It has been found that the compositions according to the invention allow to produce emulsions having a very high color intensity, and color stability with a low turbidity. These compositions can be used for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions. The present invention furthermore refers to a process for the manufacture of a beverage by mixing the compositions with ingredients of beverages. The present invention also refers to beverages obtainable by this process.
摘要翻译：本发明涉及包含辛烯基 - 琥珀酸酐改性的阿拉伯树胶和类胡萝卜素的组合物。已经发现，根据本发明的组合物允许产生具有非常高的颜色强度和低浊度的颜色稳定性的乳液。这些组合物可用于食品饮料，动物饲料，化妆品或药物组合物的富集，强化和/或着色。本发明还涉及通过将组合物与饮料成分混合来制造饮料的方法。本发明还涉及可通过该方法获得的饮料。

26. 发明申请

US20120196057A1 COMBINATION OF VITAMIN D AND 25-HYDROXYVITAMIN D 3 审中-公开
标题翻译：维生素D和25-羟基维生素D 3的组合
公开(公告)号：US20120196057A1
公开(公告)日：2012-08-02
申请号：US13446128
申请日：2012-04-13
申请人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elisabeth Stoecklin , Kai Urban , Swen Wolfram
发明人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elisabeth Stoecklin , Kai Urban , Swen Wolfram
IPC分类号： A61K31/593 , B32B1/02 , A61P3/02 , A61K9/16
CPC分类号： A61K31/593 , A23L33/155 , A23V2002/00 , A61K9/16 , A61K31/592 , A61K45/06 , Y10T428/13 , A61K2300/00
摘要： We disclose compositions comprising Vitamin D (cholecalciferol and/or ergocalciferol) and 25-OH D3 (calcifediol), and use of those compositions to affect at least concentration, bioavailability, metabolism, or efficacy of vitamin D in a human. Forms and dosages of the composition, as well as processes for manufacturing a spray-dried formulation, are also disclosed.
摘要翻译：我们公开了包含维生素D（胆钙化甾醇和/或麦角钙化醇）和25-OH D3（calcifediol）的组合物，以及使用这些组合物至少影响维生素D在人体中的至少浓度，生物利用度，代谢或功效。还公开了组合物的形式和剂量，以及用于制造喷雾干燥制剂的方法。

27. 发明申请

US20110039811A1 TREATING HYPERGLYCEMIA WITH 25-HYDROXYVITAMIN D3 审中-公开
标题翻译：用25-羟基维生素D3处理高脂血症
公开(公告)号：US20110039811A1
公开(公告)日：2011-02-17
申请号：US12867381
申请日：2009-02-12
申请人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elizabeth Stoecklin , Kai Urban , Swen Wolfram
发明人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elizabeth Stoecklin , Kai Urban , Swen Wolfram
IPC分类号： A61K31/593 , C07C401/00 , A61P3/10 , A61P3/08
CPC分类号： A61K31/593 , A23L33/155 , A23V2002/00 , A61K31/59 , A61K2300/00 , A23V2200/326 , A23V2250/71
摘要： We disclose treating hyperglycemia in a human with 25-hydroxyvitamin D3 (calcifediol). Blood glucose is reduced to a level which is closer to normal than baseline. Vitamin D3 (cholecalciferol) may optionally be used together with 25-hydroxy vitamin D3. Forms and dosages of a pharmaceutical composition, as well as processes for manufacturing medicaments, are also disclosed.
摘要翻译：我们公开了用25-羟基维生素D3（calcifediol）治疗人的高血糖。血糖降低到比基线更接近正常水平。维生素D3（胆钙化醇）可以任选与25-羟基维生素D3一起使用。还公开了药物组合物的形式和剂量，以及制备药物的方法。

28. 发明申请

US20110039810A1 USE OF 25-HYDROXY-VITAMIN D3 TO AFFECT HUMAN MUSCLE PHYSIOLOGY 审中-公开
标题翻译：使用25-羟基维生素D3来影响人体肌肉生理
公开(公告)号：US20110039810A1
公开(公告)日：2011-02-17
申请号：US12867305
申请日：2009-02-12
申请人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elizabeth Stoecklin , Kai Urban , Swen Wolfram
发明人： Neil Robert Buck , Wouter Claerhout , Bruno H. Leuenberger , Elizabeth Stoecklin , Kai Urban , Swen Wolfram
IPC分类号： A61K31/593 , C07C401/00 , A61P21/06 , A61P21/00
CPC分类号： A61K31/593 , A23L33/155 , A23V2002/00 , A61K31/59 , Y02A50/469 , A23V2200/316 , A23V2250/7106 , A61K2300/00
摘要： We disclose the use of 25-OH D3 (calcifediol) to increase muscle strength, muscle function, or both. Vitamin D3 (cholecalciferol) may optionally be used together with 25-OH D3. Forms and dosages of a pharmaceutical composition, as well as processes for manufacturing medicaments, are also disclosed.
摘要翻译：我们公开了使用25-OH D3（calcifediol）来增加肌肉力量，肌肉功能或两者。维生素D3（胆钙化醇）可以任选地与25-OH D3一起使用。还公开了药物组合物的形式和剂量，以及制备药物的方法。

29. 发明申请

US20100136177A1 PROCESS FOR THE MANUFACTURE OF A POWDER CONTAINING CAROTENOIDS 审中-公开
标题翻译：含有碳酸球的粉末的制造方法
公开(公告)号：US20100136177A1
公开(公告)日：2010-06-03
申请号：US12526148
申请日：2008-02-04
申请人： Bruno H. Leuenberger , Bernd Schlegel , Karl Manfred Voelker
发明人： Bruno H. Leuenberger , Bernd Schlegel , Karl Manfred Voelker
IPC分类号： A23L1/275 , A23L1/303 , A23L1/0522 , A23L1/0524 , A23L1/053 , A23L1/0534
CPC分类号： A23L2/58 , A23L2/395 , A23L33/105 , A23L33/155 , A23P10/40 , A23V2002/00 , A23V2200/30 , A23V2250/211 , A23V2250/5118 , A23V2250/5114 , A23V2200/254
摘要： Process for the manufacture of a powder containing one or more carotenoids, powder obtainable by said process and food composition containing said powder.
摘要翻译：用于制造含有一种或多种类胡萝卜素的粉末的方法，所述方法可获得的粉末和含有所述粉末的食品组合物。

30. 发明申请

US20100028466A1 CAROTENOID COMPOSITIONS CONTAINING MODIFIED GUM ACACIA 审中-公开
标题翻译：含有改性GAC ACACIA的CAROTENOID组合物
公开(公告)号：US20100028466A1
公开(公告)日：2010-02-04
申请号：US12529048
申请日：2008-01-15
申请人： Andrea Hitzfelo , Bruno H. Leuenberger , Olivia Vidoni
发明人： Andrea Hitzfelo , Bruno H. Leuenberger , Olivia Vidoni
IPC分类号： A61K36/00 , A23L1/27 , A23B4/03
摘要： The present invention relates to compositions containing modified gum acacia and carotenoids, wherein the gum acacia has been subjected to a heat-treatment at a temperature between 100° C. and 115° C. for 1 to 38 hours, wherein the composition comprises less than 40 weight-% oil. It has been found that the compositions according to the invention allow to produce emulsions having a very high color intensity, color stability. These compositions can be used for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions. The present invention also refers to the preparation of such compositions, wherein it has been found that the emulsification time in the manufacturing process of the compositions can be reduced when using a modified gum acacia in carotenoid compositions with less than 40 weight-% oil. The present ‘invention furthermore refers to a process for the manufacture of a beverage by mixing the compositions with ingredients of beverages. The present invention also refers to beverages obtainable by this process.
摘要翻译：本发明涉及含有改性的阿拉伯胶和类胡萝卜素的组合物，其中阿拉伯胶已经在100℃至115℃的温度下进行1至38小时的热处理，其中组合物包含小于 40重量％油。已经发现，根据本发明的组合物允许产生具有非常高的颜色强度，颜色稳定性的乳液。这些组合物可用于食品饮料，动物饲料，化妆品或药物组合物的富集，强化和/或着色。本发明还涉及这种组合物的制备，其中已经发现当使用具有小于40重量％油的类胡萝卜素组合物中使用改性的阿拉伯树胶时，可以减少组合物制造过程中的乳化时间。本发明还涉及通过将组合物与饮料成分混合来制造饮料的方法。本发明还涉及可通过该方法获得的饮料。

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