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21. 发明授权

US08866588B2 Systems, methods, and computer program products for refreshing data 有权
标题翻译：用于刷新数据的系统，方法和计算机程序产品
公开(公告)号：US08866588B2
公开(公告)日：2014-10-21
申请号：US12464793
申请日：2009-05-12
申请人： Douglas Neal Rowitch , Zoltan Biacs , Ravikumar Varma Dandu , Donovan Trisko , Jie Wu , John Delucchi , Grant Alexander Marshall , Ashok Bhatia
发明人： Douglas Neal Rowitch , Zoltan Biacs , Ravikumar Varma Dandu , Donovan Trisko , Jie Wu , John Delucchi , Grant Alexander Marshall , Ashok Bhatia
IPC分类号： G08B5/22 , H04L12/801 , G01S19/25 , G01S19/05
CPC分类号： G01S19/258 , G01S19/05 , H04L47/12
摘要： A method performs an update for a first device that consumes information with a known expiration time. The first device operates within a network that accommodates other devices also consuming the information. The method includes setting a time for the first device to refresh the information, the time to refresh being based on a pseudorandom time offset. The method also includes sending a refresh request to a resource for the data during the set time.
摘要翻译：方法执行消耗具有已知到期时间的信息的第一设备的更新。第一个设备在网络中运行，以适应其他也会消耗信息的设备。该方法包括基于伪随机时间偏移来设置第一设备刷新信息的时间，刷新的时间。该方法还包括在设定的时间内向数据的资源发送刷新请求。

22. 发明授权

US08815260B1 Treatment of restenosis and stenosis with dasatinib 有权
标题翻译：用达沙替尼治疗再狭窄和狭窄
公开(公告)号：US08815260B1
公开(公告)日：2014-08-26
申请号：US13273731
申请日：2011-10-14
申请人： Jie Wu , Zhengming Chen , Kapil N. Bhalla
发明人： Jie Wu , Zhengming Chen , Kapil N. Bhalla
IPC分类号： A61K9/00
CPC分类号： A61K31/506
摘要： A method for treating or inhibiting artery obstructive disease, such as restenosis after angioplasty and stenting procedures and stenosis after coronary artery bypass surgery, in a subject by administering to the subject a therapeutically effective amount of dasatinib or a derivative thereof. Also provided are drug-eluting medical devices, including stents, having a therapeutically effective amount of dasatinib.
摘要翻译：在受试者中通过给予受试者治疗有效量的达沙替尼或其衍生物来治疗或抑制动脉阻塞性疾病的方法，例如血管成形术后的再狭窄和冠状动脉搭桥手术后的狭窄。还提供了具有治疗有效量的达沙替尼的药物洗脱医疗装置，包括支架。

23. 发明授权

US08619919B2 Selective coherent and non-coherent demodulation methods and apparatuses 失效
标题翻译：选择性相干和非相干解调方法和装置
公开(公告)号：US08619919B2
公开(公告)日：2013-12-31
申请号：US12904333
申请日：2010-10-14
申请人： Jie Wu , Douglas Neal Rowitch , Emilija M. Simic
发明人： Jie Wu , Douglas Neal Rowitch , Emilija M. Simic
IPC分类号： H04L27/06 , H03D1/04
CPC分类号： H04L27/227 , H04L1/0036 , H04L27/0008 , H04L27/233 , H04L2027/0024
摘要： Techniques are provided which may be implemented using various methods and/or apparatuses in a receiver of an electronic device to allow for a received signal to be demodulated using both coherent and non-coherent demodulation techniques and for selecting one of the demodulated data signals based, at least in part, on a drift rate measurement of a carrier frequency of the received signal.
摘要翻译：提供了技术，其可以使用电子设备的接收机中的各种方法和/或设备来实现，以允许使用相干和非相干解调技术来解调接收的信号，并且基于解调的数据信号中的一个，至少部分地基于接收信号的载波频率的漂移率测量。

24. 发明授权

US08535047B1 Injection mold having exhaust grooves 有权
标题翻译：具有排气槽的注射模具
公开(公告)号：US08535047B1
公开(公告)日：2013-09-17
申请号：US13451794
申请日：2012-04-20
申请人： Hai-Ming Liu , Zheng Jin , Jie Wu , Guo-Rong Huang
发明人： Hai-Ming Liu , Zheng Jin , Jie Wu , Guo-Rong Huang
IPC分类号： B29C45/63
CPC分类号： B29C45/34
摘要： An injection mold comprises a second die, a first die engaging with the second die, and an inclined pin. The first die defines an inclined pin hole. The inclined pin fixed in the inclined pin hole of the first die. The first die comprises a mold core on the first die. The mold core comprises two opposite ends. Each end defines a first exhaust groove. The inclined pin head comprises a second exhaust groove, a recessed portion, and a third exhaust groove. The second exhaust groove, the recessed portion, and the third exhaust groove communicate with the first exhaust groove. The injection mold further comprises a diverting groove located between the inclined pin and the first die, and a guide groove allows the third exhaust groove communicate with the diverting groove.
摘要翻译：注射模具包括第二模具，与第二模具接合的第一模具和倾斜销。第一模具限定倾斜的销孔。倾斜销固定在第一模具的倾斜销孔中。第一模具包括在第一模具上的模芯。模芯包括两个相对端。每个端部限定第一排气槽。倾斜销头包括第二排气槽，凹部和第三排气槽。第二排气槽，凹部和第三排气槽与第一排气槽连通。注射模具还包括位于倾斜销和第一模具之间的转向槽，并且引导槽允许第三排气槽与转向槽连通。

25. 发明授权

US08324213B2 Biaryl-spiroaminooxazoline analogues as alpha 2C adrenergic receptor modulators 失效
标题翻译：双芳基 - 螺氨基恶唑啉类似物作为α2C肾上腺素能受体调节剂
公开(公告)号：US08324213B2
公开(公告)日：2012-12-04
申请号：US13122679
申请日：2009-10-06
申请人： Kevin D. McCormick , Li Dong , Christopher W. Boyce , Manuel de Lera Ruiz , Salem Fevrier , Jie Wu , Junying Zheng , Youngong Yu , Jianhua Chao , Walter S. Won , Ashwin U. Rao , Rongze Kuang , Pauline C. Ting , Xianhai Huang , Ning Shao , Anandan Palani , Michael Y. Berlin , Robert G. Aslanian
发明人： Kevin D. McCormick , Li Dong , Christopher W. Boyce , Manuel de Lera Ruiz , Salem Fevrier , Jie Wu , Junying Zheng , Youngong Yu , Jianhua Chao , Walter S. Won , Ashwin U. Rao , Rongze Kuang , Pauline C. Ting , Xianhai Huang , Ning Shao , Anandan Palani , Michael Y. Berlin , Robert G. Aslanian
IPC分类号： A61K31/501 , A61K31/497 , A61K31/506 , A61K31/4439 , A61K31/427 , A61K31/423 , C07D235/02 , C07D405/02 , C07D409/02 , C07D413/02 , C07D263/52
CPC分类号： A61K31/5377 , A61K31/437 , A61K31/501 , A61K31/506 , A61K31/537 , C07D235/02 , C07D263/52 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D413/14 , C07D417/10 , C07D471/04 , C07D498/10 , C07D519/00
摘要： In its many embodiments, the present invention provides a novel class of biaryi spiroaminooxazoline analogues as modulators of α2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the α2C adrenergic receptors using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了一类新颖的作为α2C肾上腺素能受体激动剂的调节剂的生物二螺吡喃恶唑啉类似物，制备这些化合物的方法，含有一种或多种这类化合物的药物组合物，制备包含一种或多种这类化合物的药物制剂的方法以及使用这些化合物或药物组合物治疗，预防，抑制或改善与α2C肾上腺素能受体相关的一种或多种病症的方法。

26. 发明申请

US20120182182A1 RECOVERY FROM POSITION AND TIME OUTLIERS IN POSITIONING 有权
标题翻译：从位置恢复和定位时间出口
公开(公告)号：US20120182182A1
公开(公告)日：2012-07-19
申请号：US13325649
申请日：2011-12-14
申请人： Wyatt Thomas Riley , Lalitaprasad V. Daita , William James Morrison , Dominic Gerard Farmer , Jie Wu
发明人： Wyatt Thomas Riley , Lalitaprasad V. Daita , William James Morrison , Dominic Gerard Farmer , Jie Wu
IPC分类号： G01S19/20
CPC分类号： G01S19/252 , G01S19/20 , G01S19/25 , G01S19/45
摘要： A mobile device may use one or more outlier detectors to detect likelihoods that an outlier condition exists for a satellite positioning system (SPS) position fix. In some implementations, an outlier detector may compare a computed position fix to an element of assistance data to generate an outlier likelihood. A decision to perform a recovery operation may be made based, at least in part, on a generated outlier likelihood. In some implementations, a computed reliability of the position fix may also be considered in making a recovery decision.
摘要翻译：移动设备可以使用一个或多个异常值检测器来检测对于卫星定位系统（SPS）位置锁定存在异常值状态的可能性。在一些实现中，异常值检测器可以将计算出的位置定位与辅助数据的元素进行比较以产生异常值似然。可以至少部分地基于生成的异常值可能性来进行执行恢复操作的决定。在一些实施方案中，在进行恢复决定时也可以考虑定位的计算可靠性。

27. 发明申请

US20120033716A1 TIME-SETTING IN SATELLITE POSITIONING SYSTEM RECEIVERS 有权
标题翻译：卫星定位系统接收机的时间设置
公开(公告)号：US20120033716A1
公开(公告)日：2012-02-09
申请号：US12853182
申请日：2010-08-09
申请人： Duong A. Hoang , Douglas Neal Rowitch , Jie Wu , Emilija M. Simic , Dominic Gerard Farmer
发明人： Duong A. Hoang , Douglas Neal Rowitch , Jie Wu , Emilija M. Simic , Dominic Gerard Farmer
IPC分类号： H04B1/707
CPC分类号： H04B1/70758 , G01S19/243 , G01S19/246 , H04B2201/70715
摘要： Techniques are provided which may be implemented using various methods and/or apparatuses in a receiver and/or other like device to determine an SPS time using SPS signals based on a correlation process. A verification process may be performed, for example, that verifies a maximum peak in comparison with other peak information resulting from the correlation process, for example, by considering a ratio of a maximum peak to a next maximum peak. A time-setting algorithm may be selected, for example, based, at least in part, on a time uncertainty and/or on a type of demodulation performed on the SPS signal. The time-setting algorithm may operatively control one or both of the correlation and/verification processes in a desired manner given the time uncertainty and/or type/mode of demodulation performed.
摘要翻译：提供了可以使用接收机和/或其他类似设备中的各种方法和/或设备来实现的技术，以基于相关过程来确定使用SPS信号的SPS时间。可以例如通过考虑最大峰值与下一个最大峰值的比率，来进行与相关处理产生的其他峰值信息相比较验证最大峰值的验证处理。例如，可以至少部分地基于时间不确定性和/或基于在SPS信号上执行的解调类型来选择时间设置算法。给定时间不确定性和/或解调的类型/模式，时间设置算法可以以期望的方式可操作地控制一个或两个相关和/验证过程。

28. 发明授权

US08022869B2 Apparatus and method for cross-correlation spur mitigation 有权
标题翻译：交叉相关刺激减轻的装置和方法
公开(公告)号：US08022869B2
公开(公告)日：2011-09-20
申请号：US12129397
申请日：2008-05-29
申请人： Jie Wu , Rizwan Ahmed , Emilija M. Simic , Dominic Gerard Farmer
发明人： Jie Wu , Rizwan Ahmed , Emilija M. Simic , Dominic Gerard Farmer
IPC分类号： G01S19/24 , G01S19/37
CPC分类号： G01S19/21
摘要： An apparatus and method for cross-correlation spur mitigation comprising choosing from a plurality of peak measurements, a first peak measurement with a first carrier-to-noise density estimate and a first Doppler offset measurement, and a second peak measurement with a second carrier-to-noise density estimate and a second Doppler offset measurement to form a pair; calculating a carrier-to-noise density difference based on the first carrier-to-noise density estimate and the second carrier-to-noise density estimate; calculating a Doppler difference based on the first Doppler offset measurement and the second Doppler offset measurement; comparing the carrier-to-noise density difference to a carrier-to-noise density threshold; and comparing the Doppler difference to at least one Doppler threshold.
摘要翻译：一种用于互相关刺激减轻的装置和方法，包括从多个峰值测量中选择具有第一载波噪声密度估计和第一多普勒偏移测量的第一峰值测量，以及使用第二载波 - 噪声密度估计和第二多普勒偏移测量以形成一对; 基于所述第一载波噪声密度估计和所述第二载波噪声密度估计来计算载波噪声密度差; 基于第一多普勒偏移测量和第二多普勒偏移测量来计算多普勒差; 将载波噪声密度差与载波噪声密度阈值进行比较; 以及将多普勒差异与至少一个多普勒阈值进行比较。

29. 发明申请

US20090010366A1 METHOD AND DEVICE FOR SUPPRESSING NARROWBAND INTERFERENCE 有权
标题翻译：用于抑制窄带干扰的方法和装置
公开(公告)号：US20090010366A1
公开(公告)日：2009-01-08
申请号：US11817553
申请日：2006-02-24
申请人： Jie Wu , Jinlin Zhang , Shijie Yang
发明人： Jie Wu , Jinlin Zhang , Shijie Yang
IPC分类号： H03D1/04
CPC分类号： H04B1/1036 , H04B1/7102
摘要： The method obtains an interference detection result by detecting sampled digital signals in real time in a transform domain, then maps the interference detection result into an interference suppression pulse function on the basis of a unit noise pulse function, and carries out interference suppression filtering in the transform domain according to the interference suppression pulse function. The present invention is capable of detecting narrowband interference such as monotone, frequency modulation, and phase modulation interferences in a receive channel adaptively in real-time, and suppressing the interference adaptively according to the quantity, energy and bandwidth of the interference, so as to reduce the influence of the interference. Therefore, the present invention may enhance robustness of the communication system against interference. Moreover, the present invention does not need multiple notch devices, costs low and may be implemented simply and reliably.
摘要翻译：该方法通过在变换域中实时检测采样数字信号，获得干扰检测结果，然后基于单位噪声脉冲函数将干扰检测结果映射到干扰抑制脉冲功能，并在干扰抑制滤波中进行干扰抑制滤波根据干扰抑制脉冲函数变换域。本发明能够实时地自适应地检测接收信道中的单调，调频和相位调制干扰等窄带干扰，并根据干扰的数量，能量和带宽自适应地抑制干扰，从而减少干扰的影响。因此，本发明可以提高通信系统的抗干扰性。此外，本发明不需要多个切口装置，成本低廉并且可以简单可靠地实现。

30. 发明申请

US20080175932A1 Method for Decreasing Nicotine and Other Substance Use in Humans 审中-公开
公开(公告)号：US20080175932A1
公开(公告)日：2008-07-24
申请号：US12013089
申请日：2008-01-11
申请人： Jie Wu
发明人： Jie Wu
IPC分类号： A61K36/18 , A61K31/4353 , A61P25/34 , A61P25/30 , A61P25/00
CPC分类号： A61K36/185
摘要： A method for decreasing nicotine and other substance use in humans is disclosed. Tetrahydroberberine (THB) and its analogs, l-Tetrahydropalmatine (l-THP) and l-Stepholidine (l-SPD), are present in and can be isolated from several plants in the Magnoliidae superorder. According to the disclosed method, THB and its analogs are used to block nicotine-induced DA release, and modulate heterologous or homoeric expression of human nicotinic acetylcholine receptors (nAChR) in humans. Specifically, THB exhibits bi-directory modulation of α4β2-nAChR-mediated currents induced by nicotine. THB also shows predominant inhibition on homologously expressed α7-nAChR function. Thus, according to the disclosed method, THB is used to simultaneous blockade midbrain DA system function, the brain reward center, and neuronal α4β2- and α7-nAChR function, the major nicotine targets in the brain. Therefore, THB and its analogs serve as a novel class of natural compounds to decrease nicotine dependence in humans. Furthermore other substances, such as alcohol, cocaine, and opiates, also operate by triggering the brain reward center, resulting in a cycle of substance or alcohol abuse. THB and its analogs can be used to decrease use of substances such as alcohol, cocaine, and opiates. Finally, because THB and its analogs are DA antagonists, THB and its analogs can also be used as a treatment for Parkinson's Disease, Alzheimer's Disease and Schizophrenia.

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