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21. 发明授权

US06694983B2 Delivery methods for left ventricular conduit 失效
公开(公告)号：US06694983B2
公开(公告)日：2004-02-24
申请号：US10092916
申请日：2002-03-08
申请人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
发明人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
IPC分类号： A61B1900
CPC分类号： A61M25/0147 , A61B2017/00247 , A61B2017/00252 , A61B2017/22071 , A61B2017/22095 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61F2/95 , A61F2/958 , A61M25/0152 , A61M25/0155 , A61M25/0194 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , A61M2025/1097 , A61M2210/125
摘要： Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.

22. 发明授权

US06641610B2 Valve designs for left ventricular conduits 失效
标题翻译：阀门设计用于左心室导管
公开(公告)号：US06641610B2
公开(公告)日：2003-11-04
申请号：US09368393
申请日：1999-08-04
申请人： Scott J. Wolf , Greg R. Furnish , Todd A. Hall , David Y. Phelps , Peter J. Wilk , Nancy C. Briefs , William Santamore , Daniel Burkhoff
发明人： Scott J. Wolf , Greg R. Furnish , Todd A. Hall , David Y. Phelps , Peter J. Wilk , Nancy C. Briefs , William Santamore , Daniel Burkhoff
IPC分类号： A61F206
CPC分类号： A61F2/94 , A61F2/06 , A61F2/2493 , A61F2/848 , A61F2/958 , A61F2002/821 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61M39/24
摘要： Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉狭窄或闭塞提供旁路。导管适于定位在心肌中以提供血液从冠状动脉血管流过冠状动脉的阻塞或狭窄位置的通道。导管具有定位在其中的单向阀，以防止血液从冠状动脉回流进心室。

23. 发明授权

US06387119B2 Delivery methods for left ventricular conduit 失效
标题翻译：输送方法为左心室导管
公开(公告)号：US06387119B2
公开(公告)日：2002-05-14
申请号：US09796590
申请日：2001-03-02
申请人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
发明人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
IPC分类号： A61F206
CPC分类号： A61M25/0147 , A61B2017/00247 , A61B2017/00252 , A61B2017/22071 , A61B2017/22095 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61F2/95 , A61F2/958 , A61M25/0152 , A61M25/0155 , A61M25/0194 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , A61M2025/1097 , A61M2210/125
摘要： Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the:.myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.
摘要翻译：本文描述了用于将支架或管道和其他装置输送到患者的心肌中的各种方法和装置。一个优选的支架递送系统通过使输送导管通过冠状动脉阻塞或通过冠状静脉或通过在阻塞周围形成的通道或隧道周围的阻塞来推进进入心肌中的插入部位。在一个实施例中，一旦输送导管的远端与心肌相邻，则通过致动安装到导管的可扩展转向引导件，在导管中产生成角度的弯曲部，其与血管的壁配合以使导管转动。然后，导丝通过输送导管进入心肌。在另一个实施例中，尖端偏转拉线从输送导管的远端延伸，可以被致动以转向然后插入心肌。在另一个实施例中，面向插入部位的出口端口设置在导管内或安装在导管上的球囊上，使得导丝线可以被引导通过内腔并且离开出口进入心肌。一旦导丝穿刺入心肌，就使用倒刺，气球或其他可致动部件来固定导丝，以将导丝固定到心肌。随后，使用推拉机构，支架和其他医疗装置可以在导丝上前进进入心肌。

24. 发明授权

US06302892B1 Blood flow conduit delivery system and method of use 失效
标题翻译：血流导管输送系统及使用方法
公开(公告)号：US06302892B1
公开(公告)日：2001-10-16
申请号：US09368644
申请日：1999-08-04
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61F1100
CPC分类号： A61F2/2493 , A61B2017/00252 , A61F2/064
摘要： Described herein is a catheter system for delivering an L-shaped conduit into the body of a patient between the left ventricle and coronary artery. A shunt preferably made of semirigid material is inserted into the lumen of a delivery catheter. The delivery catheter is advanced within the patient until its distal end is located adjacent to the desired insertion site, which is preferably the junction between a coronary artery and passageway formed in the myocardium between the left ventricle and coronary artery. A proximal section of the shunt is first advanced out of the delivery catheter into the myocardial passageway. A distal section of the shunt is advanced into the coronary artery, preferably by advancing the distal section of the shunt into the myocardial passageway and then pulling the distal section back into the coronary artery, or by pushing the distal section of the shunt in a folded configuration out of the delivery catheter into the coronary artery. In one embodiment, the shunt is made of a collapsible material for insertion into the delivery catheter, the shunt expanding upon removal from the delivery catheter.
摘要翻译：这里描述的是用于将L形导管输送到左心室和冠状动脉之间的患者体内的导管系统。优选由半刚性材料制成的分流器插入输送导管的内腔中。输送导管在患者体内前进，直到其远端位于所需插入位置附近，该位置优选为冠状动脉与左心室和冠状动脉之间的心肌中形成的通路之间的连接点。分流器的近端部分首先从输送导管进入心肌通道。分流器的远端部分推进到冠状动脉中，优选地通过使分流器的远端部分进入心肌通道，然后将远端部分拉回冠状动脉，或者通过将分流器的远端部分推向折叠配置输出导管进入冠状动脉。在一个实施例中，分流器由用于插入输送导管的可折叠材料制成，在从输送导管移除时分流器膨胀。

25. 发明授权

US06261304B1 Delivery methods for left ventricular conduit 失效
公开(公告)号：US06261304B1
公开(公告)日：2001-07-17
申请号：US09368868
申请日：1999-08-04
申请人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps
发明人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps
IPC分类号： A61M2900
CPC分类号： A61M25/0147 , A61B2017/00247 , A61B2017/00252 , A61B2017/22071 , A61B2017/22095 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61F2/95 , A61F2/958 , A61M25/0152 , A61M25/0155 , A61M25/0194 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , A61M2025/1097 , A61M2210/125
摘要： Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.

26. 发明授权

US06253768B1 Vascular graft bypass 失效
标题翻译：血管移植旁路
公开(公告)号：US06253768B1
公开(公告)日：2001-07-03
申请号：US09368483
申请日：1999-08-04
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61B1900
CPC分类号： A61F2/2493 , A61F2/06 , A61F2/2412
摘要： Improved methods of treatment of diseased or occluded vascular grafts in patients having undergone coronary artery bypass or other bypass surgery are disclosed. Deployment of a conduit in the myocardium at a site distal to the site of attachment of the coronary artery bypass graft allows oxygenated blood to flow from a chamber in the heart directly into the coronary artery, bypassing blockages in the coronary artery and the graft originally used to bypass the coronary artery. To ensure proper positioning, the conduit is delivered through the graft to the myocardium. A new lining for the existing vein graft and methods of delivery are also disclosed.
摘要翻译：公开了经历冠状动脉搭桥或其他旁路手术的患者中改善的患病或闭塞的血管移植物的治疗方法。在远端冠状动脉旁路移植物附着部位的心肌部分导管允许氧合血液从心脏中的室直接流入冠状动脉，绕过冠状动脉阻塞和最初使用的移植物绕过冠状动脉。为了确保正确定位，将导管通过移植物输送到心肌。还公开了现有静脉移植物和递送方法的新衬砌。

27. 发明授权

US06231496B1 Medical treatment method 失效
标题翻译：医疗方法
公开(公告)号：US06231496B1
公开(公告)日：2001-05-15
申请号：US09349003
申请日：1999-07-07
申请人： Peter J. Wilk , Mitchell N. Essig
发明人： Peter J. Wilk , Mitchell N. Essig
IPC分类号： A61B1752
CPC分类号： A61N2/06 , A61F6/06 , A61F6/14 , A61N1/406 , A61N5/02
摘要： In a sterilization method a plethora of magnetizable metal particles are deposited into a uterus of a living female organism. Subsequently, a magnet is placed near an external skin surface of the female organism near the uterus to thereby cause at least some of the metal particles to embed in a myometrium or endometrium of the uterus. The metal particles may be magnetized prior to deposition in the uterus. The particles are advantageously formed to have a sharp end which easily penetrates into the uterine lining. Each particle is magnetized so that the sharp end has a predetermined magnetic pole, whereby a magnet with the opposite pole placed against the organism results in an embedding of the sharp end in the uterine lining. In addition, microwave radiation is optionally transmitted into the female organism in a region about the uterus after the embedding of the metal particles in the myometrium or endometrium.
摘要翻译：在灭菌方法中，大量可磁化的金属颗粒沉积到活的女性生物体的子宫中。随后，将磁体放置在子宫附近的女性生物的外部皮肤表面附近，从而使至少一些金属颗粒嵌入子宫的子宫肌层或子宫内膜中。金属颗粒可以在沉积在子宫内之前被磁化。有利地，颗粒形成具有容易渗入子宫衬里的尖端。每个颗粒被磁化，使得尖端具有预定的磁极，由此具有相对极的磁体抵靠生物导致将尖端嵌入子宫衬里。此外，在将金属颗粒嵌入子宫内膜或子宫内膜后，微波辐射可选地在子宫周围的区域中传播到雌性生物体中。

28. 发明授权

US06199555B1 Cancer treatment method 失效
标题翻译：癌症治疗方法
公开(公告)号：US06199555B1
公开(公告)日：2001-03-13
申请号：US09071430
申请日：1998-05-01
申请人： Peter J. Wilk , R. Neil Sudol
发明人： Peter J. Wilk , R. Neil Sudol
IPC分类号： A61B1900
CPC分类号： A61B18/04 , A61B18/08 , A61B2018/046
摘要： In a method for treating cancer, a tube is inserted into a patient, so that a distal end of the tube is disposed proximately to a tumor. A sclerosing agent such as a concentrated sugar solution is then fed through the tube into the patient and into the tumor. The tube can take the form of a catheter which is introduced into the patient through the patient's vascular system.
摘要翻译：在治疗癌症的方法中，将管插入患者体内，使得管的远端靠近肿瘤设置。然后将诸如浓缩糖溶液的硬化剂通过管进入患者并进入肿瘤。管可以采取通过患者血管系统引入患者体内的导管的形式。

29. 发明授权

US06196230B1 Stent delivery system and method of use 失效
标题翻译：支架输送系统及使用方法
公开(公告)号：US06196230B1
公开(公告)日：2001-03-06
申请号：US09150181
申请日：1998-09-10
申请人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps , Vincent Pompili
发明人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps , Vincent Pompili
IPC分类号： A61B1900
CPC分类号： A61F2/958 , A61B2017/00247 , A61B2017/00252 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61M25/10 , A61M25/1006 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , Y10S623/903
摘要： Described herein are various methods and apparatuses for delivering stents and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.
摘要翻译：这里描述了用于将支架和其他装置输送到患者的心肌中的各种方法和装置。一个优选的支架递送系统通过使输送导管通过冠状动脉阻塞或通过冠状静脉或通过在阻塞周围形成的通道或隧道周围的阻塞来推进进入心肌中的插入部位。在一个实施例中，一旦输送导管的远端与心肌相邻，则通过致动安装到导管的可扩展转向引导件，在导管中产生成角度的弯曲部，其与血管的壁配合以使导管转动。然后，导丝通过输送导管进入心肌。在另一个实施例中，尖端偏转拉线从输送导管的远端延伸，可以被致动以转向然后插入心肌。在另一个实施例中，面向插入部位的出口端设置在导管内或安装在导管上的球囊上，使得导丝可以被引导通过内腔并离开出口进入心肌。一旦导丝穿刺入心肌，就使用倒刺，气球或其他可致动部件来固定导丝，以将导丝固定到心肌。随后，使用推拉机构，支架和其他医疗装置可以在导丝上前进进入心肌。

30. 发明授权

US06182557B2 Auxiliary cooking surfaces 失效
标题翻译：辅助烹饪面
公开(公告)号：US06182557B2
公开(公告)日：2001-02-06
申请号：US09426820
申请日：1999-10-22
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A47J3710
CPC分类号： A47J37/108
摘要： An insert for a frying pan is designed to provide a warming or holding function to an existing cooking function for a conventional frying pan. An insert consists of a segment of material of an appropriate thermal conductance shaped to fit against an edge or lip of a conventional pan of a given diameter. The segment is covered with a non-stick surface to protect an existing pan cooking surface and provide the usual benefits of non-stick food preparation surfaces. The insert is provided with a combined handle and clip for attachment to a side wall of an existing pan, and easy removal of a heated insert covered with prepared foodstuff.
摘要翻译：用于煎锅的插入物被设计成为常规煎锅的现有烹饪功能提供加温或保持功能。插入物由适当的导热部分的材料构成，其形状适合于给定直径的常规锅的边缘或唇缘。该段被不粘表面覆盖以保护现有的锅烹饪表面并提供不粘食品制备表面的通常益处。插入件具有组合的手柄和夹子，用于附接到现有的锅的侧壁，并且容易地移除被制备的食物覆盖的加热的插入物。

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