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21. 发明申请

US20100236002A1 FLEXIBLE WIRE FOR REMOVING SCALE IN PIPE 有权
标题翻译：用于在管中移除尺寸的柔性线
公开(公告)号：US20100236002A1
公开(公告)日：2010-09-23
申请号：US12675559
申请日：2008-09-02
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： B08B9/00
CPC分类号： B08B9/045 , B08B7/02 , D07B5/00
摘要： Provided is an apparatus for removing scale in a pipe. More particularly, provided is a flexible wire which is inserted in a pipe and rotated in a high speed during operation of an apparatus to remove scale produced in the pipe by striking. The flexible wire for removing scale in pipe includes: a main wire line which is formed by alternately winding a central wire line with clockwise and counterclockwise wires along a longitudinal direction of the central wire line; an auxiliary wire line which is a single line having a diameter smaller than that of the main wire line and extends in a longitudinal direction of the main wire line; and an outermost wire which winds the auxiliary wire line so as to bind the auxiliary wire line and the main wire line. Accordingly, a diameter of rotation becomes large due to a centrifugal force at a high speed rotation, so that scale produced in a large-diameter pipe can be effectively removed. In addition, a scale removing ability can be greatly improved.
摘要翻译：提供一种用于去除管道中的垢的装置。更具体地，提供了一种柔性线，其插入管中并且在设备的操作期间以高速旋转，以通过冲击去除在管中产生的垢。用于去除管道中的垢的柔性线包括：主线路，其通过沿着中心线线的纵向方向交替地缠绕中心线线与顺时针和逆时针导线; 辅助线线，其是直径小于主线路直径的直线，并且在主线路的纵向方向上延伸; 以及最外侧的线，其使辅助线线卷绕以使辅助线线和主线线路接合。因此，由于高速旋转时的离心力，旋转直径变大，能够有效地除去大径管中产生的氧化皮。另外，能够大幅提高除垢能力。

22. 发明申请

US20100000035A1 Flexible Wire for Removing Pipe Scale 有权
标题翻译：用于去除管道秤的柔性线
公开(公告)号：US20100000035A1
公开(公告)日：2010-01-07
申请号：US12298515
申请日：2007-04-20
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： B08B9/00
CPC分类号： B08B9/045
摘要： The present invention relates to a flexible wire (100), which is inserted in a pipe and rotated in al high sped to remove scale produced in a pipe by striking. A flexible wire (100) for removing pipe scales comprising: a main wire (110) having plural wires twisted in a spiral direction a one body, wherein the main wire (110) has an overall straight shape; and an auxiliary wire (120) having plural wires twisted in a spiral direction as one body, of which a diameter is substantially smaller than a diameter of the main wire (110), wherein the auxiliary wire (120) is secured to the main wire (110) and has an overall repeated S-shape.
摘要翻译：本发明涉及一种柔性线（100），其被插入管中并以高速旋转以通过冲击除去在管中产生的垢。 1.一种用于除去管鳞的柔性线（100），包括：主线（110），其具有沿螺旋方向扭曲的多根线，一根主体，其中所述主线（110）具有整体直线形状; 以及辅助线（120），其具有沿着螺旋方向扭绞的多根线，作为一体，其直径大致小于所述主线（110）的直径，其中所述辅助线（120）固定到所述主线（110）并且具有总体重复的S形。

23. 发明授权

US08835154B2 Microorganism having enhanced L-amino acids productivity and process for producing L-amino acids using the same 有权
标题翻译：具有增强的L-氨基酸生产力的微生物和使用其生产L-氨基酸的方法
公开(公告)号：US08835154B2
公开(公告)日：2014-09-16
申请号：US13980137
申请日：2012-01-18
申请人： Kwang Ho Lee , Keun Chul Lee , Seok Myung Lee , Young Bin Hwang
发明人： Kwang Ho Lee , Keun Chul Lee , Seok Myung Lee , Young Bin Hwang
IPC分类号： C12N1/20 , C12N1/21 , C12P1/04 , C12P13/22 , C12P13/08 , C12N9/12 , C07K14/245 , C12N15/70
CPC分类号： C12N15/70 , C07K14/245 , C12N9/1007 , C12N9/1205 , C12P13/04 , C12P13/08 , C12P13/227 , C12Y201/01 , C12Y207/01023
摘要： A microorganism of the genus Escherichia having enhanced L-amino acid productivity, wherein the microorganism is transformed to have an enhanced NAD kinase activity and an inactivated activity of an enzyme having an amino acid sequence of SEQ ID NO: 2 encoded by tehB gene and a method for producing L-amino acids using the microorganism of the genus Escherichia.
摘要翻译：具有增强的L-氨基酸生产力的埃希氏菌属的微生物，其中所述微生物被转化为具有增强的NAD激酶活性和具有由tehB基因编码的SEQ ID NO：2的氨基酸序列的酶和使用埃希氏杆菌属微生物生产L-氨基酸的方法。

24. 发明申请

US20140057311A1 Device For High Throughput Investigations Of Multi-Cellular Interactions 有权
标题翻译：多通道相互作用的高通量调查装置
公开(公告)号：US20140057311A1
公开(公告)日：2014-02-27
申请号：US13876293
申请日：2011-09-29
申请人： Roger Dale Kamm , Haruhiko Harry Asada , Waleed Ahmed Farahat , Ioannis K. Zervantonakis , Levi B. Wood , Chandrasekhar Kothapalli , Seok Chung , Jeffrey D. Macklis , Suzanne Tharin , Johanna Varner , Young Kum Park , Kwang Ho Lee , Le Thanh Tu Nguyen , Choong Kim
发明人： Roger Dale Kamm , Haruhiko Harry Asada , Waleed Ahmed Farahat , Ioannis K. Zervantonakis , Levi B. Wood , Chandrasekhar Kothapalli , Seok Chung , Jeffrey D. Macklis , Suzanne Tharin , Johanna Varner , Young Kum Park , Kwang Ho Lee , Le Thanh Tu Nguyen , Choong Kim
IPC分类号： G01N33/50
CPC分类号： G01N33/5008 , B01L3/502753 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , C12M23/16 , C12M23/22 , C12M25/14 , C12M29/04 , G01N33/5011 , G01N33/5029 , G01N33/5058 , G01N33/5064
摘要： Provided herein are microfluidic devices that can be used as a 3D bioassay, e.g., for drug screening, personalized medicine, tissue engineering, wound healing, and other applications. The device has a series of channels {e.g., small fluid channels) in a small polymer block wherein one or more of the channels can be filled with a biologically relevant gel, such as collagen, which is held in place by posts. As shown herein, when the device is plated with cells such as endothelial cells, new blood vessels grow in the gel, which is thick enough for the cells to grow in three dimensions. Other channels, e.g., fluid channels, allow drugs or biological material to be exposed to the 3D cell growth. Cells, such as endothelial cells, can be cultured and observed as they grow on the surface of a 3D gel scaffold, where e.g., rates of angiogenesis can be measured, as well as intervascularization and extravascularization of cancerous cells.
摘要翻译：本文提供的微流体装置可用作3D生物测定，例如用于药物筛选，个性化医学，组织工程，伤口愈合和其它应用。该装置在小聚合物嵌段中具有一系列通道（例如，小的流体通道），其中一个或多个通道可以填充生物相关凝胶，例如通过柱保持在适当位置的胶原。如本文所示，当装置镀有诸如内皮细胞的细胞时，新的血管在凝胶中生长，其足够厚以使细胞在三维中生长。其他通道，例如流体通道，允许药物或生物材料暴露于3D细胞生长。可以在3D凝胶支架的表面上生长细胞，例如内皮细胞，并且观察细胞，其中例如可以测量血管发生的速率，以及癌细胞的血管间血管形成和血管外再造。

25. 发明申请

US20140024087A1 MICROORGANISM HAVING ENHANCED L-AMINO ACIDS PRODUCTIVITY AND PROCESS FOR PRODUCING L-AMINO ACIDS USING THE SAME 有权
标题翻译：具有增强的L-氨基酸生产力的微生物和使用该氨基酸生产L-氨基酸的方法
公开(公告)号：US20140024087A1
公开(公告)日：2014-01-23
申请号：US13980137
申请日：2012-01-18
申请人： Kwang Ho Lee , Keun Chul Lee , Seok Myung Lee , Young Bin Hwang
发明人： Kwang Ho Lee , Keun Chul Lee , Seok Myung Lee , Young Bin Hwang
IPC分类号： C12P13/22 , C12P13/08 , C12N15/70
CPC分类号： C12N15/70 , C07K14/245 , C12N9/1007 , C12N9/1205 , C12P13/04 , C12P13/08 , C12P13/227 , C12Y201/01 , C12Y207/01023
摘要： A microorganism of the genus Escherichia having enhanced L-amino acid productivity, wherein the microorganism is transformed to have an enhanced NAD kinase activity and an inactivated activity of an enzyme having an amino acid sequence of SEQ ID NO: 2 encoded by tehB gene and a method for producing L-amino acids using the microorganism of the genus Escherichia.
摘要翻译：具有增强的L-氨基酸生产力的埃希氏菌属的微生物，其中所述微生物被转化为具有增强的NAD激酶活性和具有由tehB基因编码的SEQ ID NO：2的氨基酸序列的酶和使用埃希氏杆菌属微生物生产L-氨基酸的方法。

26. 发明授权

US08486670B2 Method of producing L-threonine using Escherichia coli strain with phosphoenolpyruvate carboxylase promoter replaced with cysteine synthase promoter 有权
标题翻译：使用大肠杆菌菌株产生L-苏氨酸的方法用磷酸烯醇丙酮酸羧化酶启动子替换为半胱氨酸合成酶启动子
公开(公告)号：US08486670B2
公开(公告)日：2013-07-16
申请号：US13658369
申请日：2012-10-23
申请人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
发明人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
IPC分类号： C12P13/08
CPC分类号： C12P13/08 , C12N9/1085 , C12N9/88
摘要： An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
摘要翻译：公开了其中染色体上的磷酸烯醇式丙酮酸羧化酶（ppc）基因的启动子被半胱氨酸合成酶（cysK）基因的启动子取代的产生L-苏氨酸的大肠杆菌以及通过使用它们产生L-苏氨酸的方法。重组大肠杆菌可以以高产率生产L-苏氨酸，因此可广泛用于医药，制药和饲料工业，特别是用于动物饲料。

27. 发明授权

US08261397B2 Flexible wire for removing pipe scale 有权
标题翻译：用于去除管道的柔性线
公开(公告)号：US08261397B2
公开(公告)日：2012-09-11
申请号：US12298515
申请日：2007-04-20
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： B08B9/02
CPC分类号： B08B9/045
摘要： The present invention relates to a flexible wire (100), which is inserted in a pipe and rotated in a high speed to remove scale produced in a pipe by striking. A flexible wire (100) for removing pipe scales comprising: a main wire (110) having plural wires twisted in a spiral direction as one body, wherein the main wire (110) has an overall straight shape; and an auxiliary wire (120) having plural wires twisted in a spiral direction as one body, of which a diameter is substantially smaller than a diameter of the main wire (110), wherein the auxiliary wire (120) is secured to the main wire (110) and has an overall repeated S-shape.
摘要翻译：本发明涉及一种柔性线（100），其插入管中并高速旋转以通过冲击除去在管中产生的垢。一种用于除去管鳞的柔性线（100），包括：主线（110），其具有沿着螺旋方向扭曲的多条线作为一体，其中所述主线（110）具有整体直线形状; 以及辅助线（120），其具有沿着螺旋方向扭绞的多根线，作为一体，其直径大致小于所述主线（110）的直径，其中所述辅助线（120）固定到所述主线（110）并且具有总体重复的S形。

28. 发明申请

US20120122163A1 Microorganism Which Produces L-Amino Acid and Method for Producing L-Amino Acid Using the Same 有权
标题翻译：生产L-氨基酸的微生物及使用其生产L-氨基酸的方法
公开(公告)号：US20120122163A1
公开(公告)日：2012-05-17
申请号：US13254072
申请日：2010-02-16
申请人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae
发明人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae
IPC分类号： C12P13/08 , C12N1/21
CPC分类号： C12P13/04 , C07K14/26 , C12N9/1205 , C12P13/08
摘要： The present invention relates to a microorganism belonging to the genus Escherichia sp. and a method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.
摘要翻译：本发明涉及属于埃希氏菌属的微生物。以及使用其制造L-氨基酸的方法。属于埃希氏菌属的微生物具有蔗糖同化性和L-氨基酸产生能力，其通过将编码蔗糖同化微生物的蔗糖代谢酶的基因导入属于埃希氏菌属的蔗糖非同化微生物而获得。具有L-氨基酸生产能力和蔗糖PTS（磷酸烯醇丙酮酸依赖性蔗糖磷酸转移酶系统）活性。

29. 发明申请

US20100303668A1 FUSIBLE ALLOY FOR PRESSURE RELIEF DEVICES 审中-公开
标题翻译：用于压力消除装置的合金
公开(公告)号：US20100303668A1
公开(公告)日：2010-12-02
申请号：US12445822
申请日：2006-12-28
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： C22C11/10 , C22C30/04
CPC分类号： C22C30/04 , C22C11/10 , F16K17/383
摘要： The present invention relates to a fusible alloy for pressure relief devices (PRDs), and the present invention provides a fusible alloy for PRD, the alloy comprising 29.0 to 33.0% by weight of Bi, 14.0 to 21.0% by weight of Sn, 2.0 to 5.0% by weight of In, and substantially Pb for the balance.The fusible alloy for PRD of the invention has a melting point appropriate for use according to the 110° C.-grade standards, and has excellent wettability upon melting.
摘要翻译：本发明涉及一种用于压力释放装置（PRD）的熔融合金，本发明提供一种用于PRD的可熔合金，该合金包含29.0至33.0重量％的Bi，14.0至21.0重量％的Sn，2.0至 5.0重量％，余量为大致Pb。本发明的PRD用熔融合金，根据110℃级标准，具有适合使用的熔点，熔融时润湿性优异。

30. 发明申请

US20100089400A1 VALVE APPARATUS FOR MOVABLE OXYGEN CYLINDER 有权
标题翻译：可移动氧气瓶的阀门设备
公开(公告)号：US20100089400A1
公开(公告)日：2010-04-15
申请号：US12385337
申请日：2009-04-06
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： A62B9/02
CPC分类号： F16K1/305 , Y10T137/2544 , Y10T137/87241
摘要： Provided is a valve apparatus for a movable oxygen cylinder which has a function of a post valve for an oxygen generation system for household use and that of a post valve for general medical care, selectively. The valve apparatus includes: a valve body whose one side is combined with the movable oxygen cylinder, and which communicates with a discharge port at the other side thereof along a path from one side thereof lengthily therein, to thus discharge out the oxygen of the oxygen cylinder through the discharge port, and which includes an opening which opened outwards from an insertion space provided along the path; a post valve which is installed at the other side of the valve body and controls discharge of oxygen through the discharge port from the oxygen cylinder according to operation of a lever; and a charge adapter whose one side is detachably installed in the opening of the insertion space, and which charges oxygen supplied from the outside into the oxygen cylinder when the post valve closes the path, and discharges oxygen of the oxygen cylinder through the discharge port when the post valve opens the path.
摘要翻译：提供一种用于可动氧气瓶的阀装置，其具有用于家用氧气产生系统的柱阀和用于一般医疗保健的后阀的功能。阀装置包括：阀体，其一侧与可动氧气缸组合，并且在其另一侧与其长度方向上的排出口连通，从而排出氧气的氧气圆柱体通过排出口，其包括从沿着路径设置的插入空间向外开口的开口; 一个安装在阀体另一侧的柱阀，根据杆的操作控制通过排出口的氧气从氧气瓶排出; 以及充电适配器，其一侧可拆卸地安装在插入空间的开口中，并且当柱阀闭合路径时将从外部供应的氧充入氧气瓶中，并且当氧气瓶通过排出口排出氧气时，柱阀打开路径。

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