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21. 发明申请

US20080045983A1 Devices and methods for anchoring tissue 审中-公开
公开(公告)号：US20080045983A1
公开(公告)日：2008-02-21
申请号：US11894397
申请日：2007-08-20
申请人： John To , Niel Starksen , Mariel Fabro , Nathan Pliam , Karl Im
发明人： John To , Niel Starksen , Mariel Fabro , Nathan Pliam , Karl Im
IPC分类号： A61B17/122
CPC分类号： A61F2/2445 , A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/0644 , A61B17/0682 , A61B2017/00243 , A61B2017/00783 , A61B2017/00867 , A61B2017/0409 , A61B2017/0414 , A61B2017/0443 , A61F2/0811
摘要： Anchors, anchoring systems, anchor delivery devices, and method of using anchors are described. An anchor may be a flexible anchor having two curved legs that cross in a single turning direction to form a loop, wherein the legs are adapted to penetrate tissue. The ends of the curved legs may be blunt or sharp. The anchor can assume different configurations such as a deployed configuration and a delivery configuration, and the anchor may switch between these different configurations. In operation, the anchor may be inserted into tissue by releasing the anchor from a delivery configuration so that the anchor self-expands into the deployed configuration, so that the legs of the anchor may penetrate the tissue in a curved pathway.

22. 发明申请

US20050273138A1 Devices and methods for anchoring tissue 审中-公开
标题翻译：用于锚定组织的装置和方法
公开(公告)号：US20050273138A1
公开(公告)日：2005-12-08
申请号：US11202474
申请日：2005-08-11
申请人： John To , Niel Starksen , Mariel Fabro , Nathan Pliam , Karl Im
发明人： John To , Niel Starksen , Mariel Fabro , Nathan Pliam , Karl Im
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61B17/068 , A61B17/08 , A61F2/08 , A61F2/24
CPC分类号： A61F2/2445 , A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/0644 , A61B17/0682 , A61B2017/00243 , A61B2017/00783 , A61B2017/00867 , A61B2017/0409 , A61B2017/0414 , A61B2017/0443 , A61F2/0811
摘要： Anchors, anchoring systems, anchor delivery devices, and method of using anchors are described. An anchor may be a flexible anchor having two curved legs that cross in a single turning direction to form a loop, wherein the legs are adapted to penetrate tissue. The ends of the curved legs may be blunt or sharp. The anchor can assume different configurations such as a deployed configuration and a delivery configuration, and the anchor may switch between these different configurations. In operation, the anchor may be inserted into tissue by releasing the anchor from a delivery configuration so that the anchor self-expands into the deployed configuration, so that the legs of the anchor may penetrate the tissue in a curved pathway.
摘要翻译：描述了锚，锚固系统，锚固装置以及使用锚的方法。锚可以是具有两个弯曲腿的柔性锚，所述两个弯曲的腿在单个转动方向上交叉以形成环，其中所述腿适于穿透组织。弯曲的腿的端部可以是钝的或尖锐的。锚可以采取不同的配置，例如部署的配置和传送配置，并且锚可以在这些不同的配置之间切换。在操作中，锚可以通过从输送构型释放锚而插入到组织中，使得锚固体自膨胀成展开构型，使得锚的腿可以以弯曲的路径穿透组织。

23. 发明申请

US20050055087A1 Devices and methods for cardiac annulus stabilization and treatment 有权
标题翻译：用于心脏瓣环稳定和治疗的装置和方法
公开(公告)号：US20050055087A1
公开(公告)日：2005-03-10
申请号：US10656797
申请日：2003-09-04
申请人： Niel Starksen
发明人： Niel Starksen
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2451 , A61F2/2466
摘要： Devices and methods generally provide enhanced stabilization, exposure and/or treatment of a cardiac valve annulus. Methods generally involve introducing a stabilizing member beneath one or more leaflets of a heart valve to engage the annulus at an intersection between the leaflets and the interior ventricular wall of the heart. Force is then applied to the stabilizing member to stabilize and/or expose the valve annulus. In some embodiments, the stabilizing member may include a series of hydraulically driven tethered anchors, such as hooks or clips, for engaging and cinching valve annulus tissue to decrease the diameter of a regurgitant valve. Alternatively, other treatments may be delivered by a stabilizing member, such as radiofrequency energy, drugs, bulking agents or shape memory stents. A second stabilizing member may also be introduced above the leaflets for further stabilization.
摘要翻译：装置和方法通常提供增强的心脏瓣膜环的稳定，暴露和/或治疗。方法通常包括在心脏瓣膜的一个或多个小叶下方引入稳定构件，以在瓣膜和心脏的室内心室壁之间的交叉处接合环状物。然后将力施加到稳定构件以使阀环稳定和/或暴露。在一些实施例中，稳定构件可以包括一系列液压驱动的栓系锚，例如钩或夹子，用于接合和收紧瓣膜环组织以减小反流阀的直径。或者，其他治疗可以由稳定构件例如射频能量，药物，填充剂或形状记忆支架递送。还可以在传单上方引入第二稳定构件以进一步稳定。

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