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21. 发明授权

US08057510B2 Plug with collet and apparatus and method for delivering such plugs 有权
标题翻译：用夹头和装置和方法插入这种插头
公开(公告)号：US08057510B2
公开(公告)日：2011-11-15
申请号：US11121715
申请日：2005-05-03
申请人： Richard S. Ginn , Daniel T. Wallace , Robert C. LaDuca
发明人： Richard S. Ginn , Daniel T. Wallace , Robert C. LaDuca
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a plug including external threads, a lumen extending between its proximal and distal ends, and an annular collet slidably disposed within the lumen. The plug is carried on a distal end of a handle device that includes an inner member with a distal end that is slidable axially within the lumen of the body for moving the collet into a reduced cross-sectional region of the lumen, thereby compressing the collet to seal the lumen, and for deploying the plug from the handle device. During use, the plug is delivered into a passage through tissue over a guide wire. Once a desired location is reached, the plug is deployed from the handle device, thereby compressing the collet and sealing the lumen. The guide wire and handle device are removed, leaving the plug to seal the passage.
摘要翻译：用于密封通过组织的通道的装置包括包括外螺纹的塞子，在其近端和远端之间延伸的内腔和可滑动地设置在内腔内的环形夹头。插头被承载在手柄装置的远端上，该手柄装置包括内部构件，该内部构件具有在主体的内腔内可轴向滑动的远端，用于将夹头移动到管腔的减小的横截面区域中，从而压缩筒夹以密封管腔，并且用于从手柄装置部署塞子。在使用过程中，塞子通过导丝被输送到穿过组织的通道中。一旦到达期望的位置，插头从手柄装置展开，从而压缩夹头并密封管腔。引导线和手柄装置被移除，留下塞子以密封通道。

22. 发明申请

US20110144668A1 CLOSURE DEVICE 有权
标题翻译：封闭装置
公开(公告)号：US20110144668A1
公开(公告)日：2011-06-16
申请号：US12897358
申请日：2010-10-04
申请人： Michael T. Carley , Richard S. Ginn , Javier Sagastegui , Jana Sagastegui , Ronald J. Jabba , William N. Aldrich , W. Martin Belef
发明人： Michael T. Carley , Richard S. Ginn , Javier Sagastegui , Jana Sagastegui , Ronald J. Jabba , William N. Aldrich , W. Martin Belef
IPC分类号： A61B17/122
CPC分类号： A61B17/064 , A61B17/0057 , A61B17/0644 , A61B17/068 , A61B90/39 , A61B2017/00004 , A61B2017/00668 , A61B2017/00867 , A61B2017/0641
摘要： A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another. The primary tines are configured such that they are offset from the axes of symmetry of the curved regions from which they extend and are connected to the curved regions by curved or linear regions or are connected directly to the curved regions. The primary tines may overlap the body and may be of different lengths.
摘要翻译：用于接合组织的夹具包括限定平面并围绕垂直于平面延伸的中心轴设置的大致环形的主体。主体包括交替的内部和外部弯曲区域，围绕夹子的周边限定Z字形图案。身体偏向平面构型，该平面构型位于平面内，并可朝向延伸出平面的横向构型偏转。齿从内部弯曲区域延伸，尖齿在平面构型中朝向中心轴线定向，并且在横向构型中平行于中心轴线。尖齿包括比主尖齿短的主要尖齿和次级齿。主尖齿可以设置在相对的内弯曲区域上并且朝向彼此定向。主尖齿被构造成使得它们偏离其延伸的弯曲区域的对称轴线，并且通过弯曲或线性区域连接到弯曲区域，或者直接连接到弯曲区域。主尖齿可能与身体重叠，并且可能具有不同的长度。

23. 发明申请

US20110071568A1 Spacer Devices Having Retainers And Systems For The Treatment Of Spinal Stenosis And Methods For Using The Same 审中-公开
标题翻译：具有用于治疗脊柱狭窄的保持器和系统的间隔装置及其使用方法
公开(公告)号：US20110071568A1
公开(公告)日：2011-03-24
申请号：US12567567
申请日：2009-09-25
申请人： Richard S. Ginn , Robert Elliott DeCou , Nicanor Domingo , Hans F. Valencia , David A. White , Scott Yerby
发明人： Richard S. Ginn , Robert Elliott DeCou , Nicanor Domingo , Hans F. Valencia , David A. White , Scott Yerby
IPC分类号： A61B17/70
CPC分类号： A61B17/7062 , A61B17/7068
摘要： Spacer devices for treating spinal stenosis are provided herein, as are methods for using the same. In some example embodiments, these devices are configured for attachment over or through the interspinous ligaments. These devices generally include a spacer portion and an attachable retainer. Also provided are systems for the delivery of the spacer devices and methods for using the same.
摘要翻译：本文提供了用于治疗脊柱狭窄的间隔装置，以及使用该狭窄装置的方法。在一些示例性实施例中，这些装置被配置为用于附接在椎间韧带上或通过棘突间韧带。这些装置通常包括间隔部分和可附接保持器。还提供了用于递送间隔装置的系统及其使用方法。

24. 发明授权

US07901428B2 Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use 有权
标题翻译：血管鞘与生物可吸收性穿刺部位闭合装置及使用方法
公开(公告)号：US07901428B2
公开(公告)日：2011-03-08
申请号：US10264306
申请日：2002-10-03
申请人： Richard S. Ginn , William N. Aldrich
发明人： Richard S. Ginn , William N. Aldrich
IPC分类号： A61D1/00
CPC分类号： A61B17/0643 , A61B17/0057 , A61B17/064 , A61B17/083 , A61B17/1285 , A61B17/3415 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641 , A61M25/0662
摘要： Apparatus and methods are provided for use in sealing a vascular puncture site. The invention includes an introducer sheath with an integrated closure component. The closure component includes a fastener and an advanceable, deformable clip having a delivery configuration in which opposing sides do not contact one another, and a deployed configuration, in which the fastener causes opposing sides of the deformable clip to close towards one another. The clip is advanced along the sheath until it pierces opposing sides of a vessel wall at a puncture site. The clip is then deformed with the fastener to draw opposing sides of the puncture together, and the sheath is withdrawn to seal the wound. The clip and fastener preferably are bioabsorbable.
摘要翻译：提供了用于密封血管穿刺部位的装置和方法。本发明包括具有集成闭合部件的引导器护套。闭合部件包括紧固件和可前进的可变形的夹子，其具有相对的侧面不彼此接触的输送构造，以及展开构造，其中紧固件使可变形夹的相对侧面彼此靠近。夹子沿护套前进，直到穿刺部位穿过血管壁的相对侧。然后夹子用紧固件变形以将穿刺的相对侧拉在一起，并且将护套取出以密封伤口。夹和紧固件优选是生物可吸收的。

25. 发明授权

US07887555B2 Closure device and methods for making and using them 有权
标题翻译：关闭装置及其制造和使用的方法
公开(公告)号：US07887555B2
公开(公告)日：2011-02-15
申请号：US10616832
申请日：2003-07-09
申请人： Michael T. Carley , Richard S. Ginn , Javier Sagastegui , Ronald J. Jabba , William N. Aldrich , W. Martin Belef
发明人： Michael T. Carley , Richard S. Ginn , Javier Sagastegui , Ronald J. Jabba , William N. Aldrich , W. Martin Belef
IPC分类号： A61B17/08
CPC分类号： A61B17/08 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/083 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00867 , A61B2017/0641 , A61B2017/081 , H03K3/356139 , H03K3/356156
摘要： A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines may include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another such that they overlap in the planar configuration.
摘要翻译：用于接合组织的夹具包括限定平面并围绕垂直于平面延伸的中心轴设置的大致环形的主体。主体包括交替的内部和外部弯曲区域，围绕夹子的周边限定Z字形图案。身体偏向平面构型，该平面构型位于平面内，并可朝向延伸出平面的横向构型偏转。齿从内部弯曲区域延伸，尖齿在平面构型中朝向中心轴线定向，并且在横向构型中平行于中心轴线。尖齿可以包括比主尖齿短的主要尖齿和次要尖齿。主尖齿可以设置在相对的内部弯曲区域上并且朝向彼此定向，使得它们在平面构造中重叠。

26. 发明授权

US07850797B2 Methods for manufacturing a clip and clip 有权
公开(公告)号：US07850797B2
公开(公告)日：2010-12-14
申请号：US12403256
申请日：2009-03-12
申请人： Michael T. Carley , Richard S. Ginn
发明人： Michael T. Carley , Richard S. Ginn
IPC分类号： C22F1/00 , A61B17/08
CPC分类号： A61B17/068 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/083 , A61B90/39 , A61B2017/00004 , A61B2017/00867 , C22C19/007 , C22F1/00 , C22F1/10 , C22F1/16
摘要： The present invention relates to a method of making clips which can be used to engage body tissue for the purpose of closing wounds. Such clips are generally annular in shape and have radially inwardly extending tines. The present invention first forms a precursor which, in one embodiment, has the tines extending radially outwardly from the annular body and then forms the clip by inverting the precursor such that the tines extend radially inwardly. In an alternate embodiment, the precursor is formed with an over-sized lateral dimension and then compressed inwardly to bring the tines closer together and to reduce the lateral dimension of the precursor. It is preferred to manufacture such clips from a superelastic alloy such as nickel-titanium, in which case the inverted or compressed precursor must be heated and quenched to heat set the clip in its final shape.

27. 发明授权

US07699774B1 Access platform for internal mammary dissection 失效
标题翻译：内部乳腺切开手术平台
公开(公告)号：US07699774B1
公开(公告)日：2010-04-20
申请号：US09385812
申请日：1999-08-30
申请人： Charles S. Taylor , William N. Aldrich , Federico J. Benetti , Richard S. Ginn , Dwight P. Morejohn , Brent Regan , Eugene E. Reis , Ivan Sepetka , William F. Witt
发明人： Charles S. Taylor , William N. Aldrich , Federico J. Benetti , Richard S. Ginn , Dwight P. Morejohn , Brent Regan , Eugene E. Reis , Ivan Sepetka , William F. Witt
IPC分类号： A61B17/02 , A61M29/00
CPC分类号： A61B17/3423 , A61B17/0206 , A61B17/025 , A61B17/3476 , A61B90/50 , A61B2017/349
摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and a sternal pad interconnected to a blade. The superior blade is pivotally coupled to the spreader member such that it naturally rises as the blades are separated. Alternatively, a vertical displacement member is operably interconnected to a blade and the spreader member and is used to vertically displace the interconnected superior blade and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor is interconnected to the blades to draw the soft tissue around an incision away from the surgeon's working area.
摘要翻译：一种进入平台，具有互连到扩张器构件的第一和第二刀片，所述第二和第二刀片横向地驱动刀片彼此分开或一起，以及与刀片互连的胸骨垫。上部叶片枢转地联接到扩展构件，使得其随着叶片分离而自然地上升。或者，垂直移位构件可操作地连接到叶片和吊架构件，并且用于垂直地移位互连的上叶片，并且因此增加外科医生的工作空间和用于解剖内部乳房动脉的视觉进入。组织牵缩器与刀片相互连接以将软组织围绕切口远离外科医生的工作区域。

28. 发明授权

US07393363B2 Lung assist apparatus and methods for use 失效
标题翻译：肺辅助装置及使用方法
公开(公告)号：US07393363B2
公开(公告)日：2008-07-01
申请号：US11421004
申请日：2006-05-30
申请人： Richard S. Ginn
发明人： Richard S. Ginn
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61F2/00 , A61F2/07 , A61F2/24 , A61F2/852 , A61F2002/043 , A61F2002/065 , A61F2002/821 , A61F2250/0063 , A61M16/0406
摘要： A lung-assist apparatus includes a tubular housing, a tubular nozzle therein, and a first valve disposed between the housing and nozzle. The housing is implanted across a bifurcation such that the nozzle extends from a first branch communicating with a healthy region of a lung towards a main passage, and terminates proximate a lateral opening in the housing that is disposed within a second branch communicating with a damaged region of the lung. During inhalation, the first valve opens to allow air flow into the first branch, and closes during exhalation to force air through the nozzle, thereby inducing a vacuum for drawing air from the damaged region. A second valve in the second branch opens during exhalation to draw air from the diseased region, and closes during inhalation to prevent air from being drawn into the damaged region.
摘要翻译：肺辅助装置包括管状壳体，管状喷嘴，以及设置在壳体和喷嘴之间的第一阀。壳体被植入跨分叉，使得喷嘴从与肺的健康区域连通的第一分支延伸到主通道，并且靠近外壳中的侧向开口终止，该外部开口设置在与受损区域连通的第二分支的肺。在吸入期间，第一阀打开以允许空气流入第一分支，并且在呼气期间关闭以迫使空气通过喷嘴，从而诱导用于从受损区域抽取空气的真空。第二分支中的第二个阀在呼气期间打开以从患病区域抽出空气，并在吸入期间关闭以防止空气被吸入损伤区域。

29. 发明授权

US07361183B2 Locator and delivery device and method of use 有权
标题翻译：定位器和配送装置及使用方法
公开(公告)号：US07361183B2
公开(公告)日：2008-04-22
申请号：US10850795
申请日：2004-05-21
申请人： Richard S. Ginn
发明人： Richard S. Ginn
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00022 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654 , A61B2017/00672 , A61B2017/22047 , A61B2034/2051 , A61B2090/062 , A61B2090/0811
摘要： This invention relates to apparatus and methods for use in sealing a vascular puncture site and to apparatus and methods for properly locating and deploying a sealing device. The locating apparatus includes a lumen which extends from an opening in the distal region of the apparatus but located proximally of the sealing device, which lumen extends to another opening in the proximal region of the device. When the distal opening is in communication with blood in a blood vessel, blood flow through the lumen and out of the proximal opening signifies such location to the user. When the sealing device is withdrawn such that the sealing device is deployed such that it blocks the blood flow into the distal port, the user will know the location of the sealing device. In a preferred embodiment, the sealing device is then withdrawn proximally a predetermined distance to assure that no part of the sealing device extends into the blood vessel lumen. The sealing device is then detached from the delivery device.
摘要翻译：本发明涉及用于密封血管穿刺部位的装置和方法以及用于适当定位和展开密封装置的装置和方法。定位装置包括从设备的远侧区域中的开口延伸但位于密封装置的近侧处的内腔，该内腔延伸到装置的近侧区域中的另一个开口。当远端开口与血管中的血液连通时，血流通过内腔并离开近端开口表示使用者的这种位置。当密封装置被抽出时，使得密封装置被展开，使得它阻止进入远端口的血流，使用者将知道密封装置的位置。在优选实施例中，然后将密封装置向近侧撤回预定距离，以确保密封装置的任何部分不延伸进入血管内腔。然后将密封装置从输送装置分离。

30. 发明授权

US07083635B2 Apparatus and methods for sealing vascular punctures 有权
公开(公告)号：US07083635B2
公开(公告)日：2006-08-01
申请号：US10423133
申请日：2003-04-24
申请人： Richard S. Ginn
发明人： Richard S. Ginn
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue communicating with a blood vessel includes a bioabsorbable plug member coupled to the distal end of a carrier member. The plug member includes a lumen extending therethrough that communicates with a lumen extending through the carrier member. A sealing member is disposed in the plug member lumen for sealing the lumen. A guide member is slidable into the lumen such that edges of a groove extending between proximal and distal portions of the guide member engage a wall of the lumen to define a bleed back lumen. The guide member is inserted into the passage until the distal portion enters the vessel. The plug member is advanced over the guide member until the plug member enters the vessel, whereupon blood enters the bleed back lumen to identify the location of the vessel relative to the plug member.

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