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21. 发明申请

US20050065536A1 Apparatus and methods for forming gastrointestinal tissue approximations 有权
标题翻译：用于形成胃肠组织近似的装置和方法
公开(公告)号：US20050065536A1
公开(公告)日：2005-03-24
申请号：US10992912
申请日：2004-11-18
申请人： Richard Ewers , Boris Reydel , Cang Lam , Eugene Chen , Brent Seybold , Rodney Brenneman , Vahid Saadat
发明人： Richard Ewers , Boris Reydel , Cang Lam , Eugene Chen , Brent Seybold , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/28 , A61B17/34 , A61B17/08
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B17/0644 , A61B17/29 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/061 , A61B2017/3445 , A61B2017/3488
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point, moving the first tissue contact point from a position initially distal to a second tissue contact point to a position proximal of the second contact point to form a tissue fold, and extending an anchor assembly through the tissue fold near the second tissue contact point.
摘要翻译：提供了设备和方法，用于通过在第一组织接触点处接合组织来形成胃肠组织折叠，将第一组织接触点从最初远端到第二组织接触点的位置移动到第二接触点的近侧的位置，以形成组织折叠，并且使锚固组件穿过第二组织接触点附近的组织褶皱延伸。

22. 发明申请

US20060020274A1 Manipulatable grasping needle 审中-公开
标题翻译：可操纵抓针
公开(公告)号：US20060020274A1
公开(公告)日：2006-01-26
申请号：US10898684
申请日：2004-07-23
申请人： Richard Ewers , Cang Lam , Vahid Saadat
发明人： Richard Ewers , Cang Lam , Vahid Saadat
IPC分类号： A61B17/04
CPC分类号： A61B17/29 , A61B17/0401 , A61B17/0469 , A61B17/0483 , A61B2017/00349 , A61B2017/2905 , A61B2017/2926
摘要： A manipulatable grasping needle is described herein. A piercing and grasping assembly generally comprises a needle body, which is optionally hollow, having a piercing tip and a grasping arm positioned proximally of the tip, wherein the grasping arm is adapted to project from the needle body and releasably retain a length of suture. Alternatively, opposing jaws can form a singular piercing tip when the jaws are closed. The assembly is positioned at the distal end of an elongate member which can be rigid or flexible for advancement through an endoscopic device. The elongate member can also comprise one or more articulatable sections to enable manipulation of the assembly into various shapes to facilitate suture and tissue manipulation. Moreover, either the needle body or grasping arm can define a notch for receiving suture material. A hooking member can also be provided to facilitate suture retrieval when grasping suture.
摘要翻译：这里描述了可操纵的把持针。穿刺和抓握组件通常包括可选地中空的针体，其具有穿刺尖端和位于尖端近侧的抓握臂，其中抓握臂适于从针体突出并且可释放地保持一定长度的缝合线。或者，当夹爪关闭时，相对的夹爪可以形成单个穿刺尖端。组件定位在细长构件的远端，细长构件的远端可以是刚性的或柔性的，用于通过内窥镜装置前进。细长构件还可以包括一个或多个可铰接部分，以使得能够将组件操纵成各种形状以便于缝合和组织操纵。此外，针体或抓握臂可以限定用于接收缝合材料的凹口。还可以提供钩构件以便于在抓住缝线时促进缝合线的取出。

23. 发明申请

US20050251161A1 Needle assembly for tissue manipulation 有权
标题翻译：用于组织操作的针组件
公开(公告)号：US20050251161A1
公开(公告)日：2005-11-10
申请号：US10955243
申请日：2004-09-30
申请人： Vahid Saadat , Chris Rothe , Richard Ewers
发明人： Vahid Saadat , Chris Rothe , Richard Ewers
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/29 , A61B2017/00349 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Needle assemblies for tissue manipulation are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. A needle deployment assembly is deployable through the tissue manipulation assembly via a handle assembly, through the tubular member, and into or through tissue. An elongate pusher is translationally disposed within a sheath of the needle deployment assembly and can be urged distally for deploying an anchor assembly from the sheath distal end. The anchor assembly is positioned distally of the pusher within the sheath.
摘要翻译：用于组织操作的针组件在本文中描述。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，位于所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。针部署组件可经由手柄组件穿过组织操纵组件展开，穿过管状构件，并且进入或穿过组织。细长的推动器平移地设置在针展开组件的护套内，并且可以向远侧推动以从护套远端展开锚固组件。锚固组件位于鞘内的推动器的远侧。

24. 发明申请

US20050272977A1 Methods and apparatus for performing endoluminal procedures 审中-公开
标题翻译：用于进行腔内手术的方法和装置
公开(公告)号：US20050272977A1
公开(公告)日：2005-12-08
申请号：US11129513
申请日：2005-05-13
申请人： Vahid Saadat , Chris Rothe , Richard Ewers , Gilbert Madrid
发明人： Vahid Saadat , Chris Rothe , Richard Ewers , Gilbert Madrid
IPC分类号： A61B1/005 , A61B1/018 , A61B1/04
CPC分类号： A61B1/0051 , A61B1/0008 , A61B1/00179 , A61B1/00183 , A61B1/018 , A61B1/04 , A61B17/29
摘要： Methods and apparatus for performing endoluminal procedures are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.
摘要翻译：本文描述了用于进行腔内手术的方法和装置。公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接离轴并且操纵感兴趣的组织区域。

25. 发明申请

US20060183975A1 Methods and apparatus for performing endoluminal procedures 审中-公开
标题翻译：用于进行腔内手术的方法和装置
公开(公告)号：US20060183975A1
公开(公告)日：2006-08-17
申请号：US11400580
申请日：2006-04-07
申请人： Vahid Saadat , Chris Rothe , Richard Ewers , Gilbert Madrid
发明人： Vahid Saadat , Chris Rothe , Richard Ewers , Gilbert Madrid
IPC分类号： A61B1/00
CPC分类号： A61B1/0051 , A61B1/0008 , A61B1/00179 , A61B1/00183 , A61B1/018 , A61B1/04 , A61B17/29
摘要： Methods and apparatus for performing endoluminal procedures are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.
摘要翻译：本文描述了用于进行腔内手术的方法和装置。公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接离轴并且操纵感兴趣的组织区域。

26. 发明申请

US20060287666A1 Apparatus and methods for endoluminal advancement 审中-公开
标题翻译：用于腔内推进的装置和方法
公开(公告)号：US20060287666A1
公开(公告)日：2006-12-21
申请号：US11154168
申请日：2005-06-15
申请人： Vahid Saadat , Eugene Chen , Tung Le , Tracy Maahs , Richard Ewers , John Cox , Chris Rothe
发明人： Vahid Saadat , Eugene Chen , Tung Le , Tracy Maahs , Richard Ewers , John Cox , Chris Rothe
IPC分类号： A61M29/00
CPC分类号： A61M25/1011 , A61B2017/22068 , A61B2017/22069 , A61M2025/1015 , A61M2025/1052
摘要： Apparatus and methods for endoluminal advancement are described herein. A shape-lockable tissue anchoring assembly generally has an elongate body, a handle assembly, and an anchoring assembly positioned at or proximal to a distal tip of the elongate body. A distal portion of the elongate body may optionally be steerable or curvable. The anchoring assembly may include various expandable or projecting anchoring features to contact and retain tissue relative to the elongate body such that pleated tissue is temporarily immobile relative to the elongate body. This anchoring can be actuated simultaneously with or independently from shape-locking of elongate body. The anchoring assembly can be actuated simultaneously with the shape-locking of the elongate body. Alternatively, the steerable distal portion of the elongate body can be angled against the pleated tissue to retain it while the endoscope is advanced relative to the pleated tissue.
摘要翻译：本文描述了腔内前进的装置和方法。可锁定形状的组织锚固组件通常具有细长主体，手柄组件和定位在细长主体的远侧末端处或近侧的锚固组件。细长主体的远端部分可以可选地是可操纵的或可调节的。锚定组件可以包括各种可膨胀或突出的锚固特征，以相对于细长体接触和保持组织，使得褶皱组织相对于细长体临时固定不动。这种锚固可以与细长体的形状锁定同时或独立地致动。锚固组件可以与细长体的形状锁定同时致动。或者，细长主体的可转向远端部分可以相对于打褶组织成角度，以在内窥镜相对于打褶组织前进时保持它。

27. 发明申请

US20050203500A1 Apparatus and methods for mapping out endoluminal gastrointestinal surgery 有权
标题翻译：用于绘制腔内胃肠手术的装置和方法
公开(公告)号：US20050203500A1
公开(公告)日：2005-09-15
申请号：US10954658
申请日：2004-09-29
申请人： Vahid Saadat , Chris Rothe , Ruey-Feng Peh , Richard Ewers
发明人： Vahid Saadat , Chris Rothe , Ruey-Feng Peh , Richard Ewers
IPC分类号： A61B17/00 , A61B18/04 , A61B19/00
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/12013 , A61B17/320016 , A61B17/32053 , A61B17/32075 , A61B17/3211 , A61B17/3478 , A61B18/14 , A61B18/1482 , A61B18/1492 , A61B90/39 , A61B2017/00269 , A61B2017/00349 , A61B2017/00818 , A61B2017/00986 , A61B2017/0411 , A61B2017/0419 , A61B2017/06052 , A61B2017/306 , A61B2017/308 , A61B2017/320044 , A61B2018/00029 , A61B2018/00244 , A61B2018/00291 , A61B2018/00494 , A61B2018/00577 , A61B2018/00595 , A61B2018/00982 , A61B2018/124 , A61B2018/1415 , A61B2018/144 , A61B2018/1467 , A61B2090/036 , A61B2090/3908 , A61B2090/3912 , A61B2090/3937 , A61B2090/395 , A61B2090/3987 , A61B2090/3991 , A61B2218/002 , A61B2218/007 , A61F5/0013
摘要： Apparatus and methods are provided for mapping out endoluminal gastrointestinal surgery, including endoluminal gastric reduction. Mapping is achieved by locally marking the interior of the gastrointestinal lumen at specified locations. In some variations, mucosectomy and/or mucosal ablation are performed to map out endoluminal GI surgery, to facilitate direct endoluminal engagement of underlying muscularis tissue and/or to initiate a wound healing response. Specialized apparatus may be provided to achieve desired spacing and/or positioning of tissue markings, as well as to actually form the markings. Methods of using apparatus of the present invention are provided.
摘要翻译：提供装置和方法用于映射腔内胃肠手术，包括腔内胃减少。通过在指定位置局部标记胃肠腔的内部来实现测绘。在一些变型中，进行粘膜切除术和/或粘膜消融以绘出腔内GI手术，以促进下面的肌层组织的直接腔内接合和/或引发伤口愈合反应。可以提供专用设备以实现组织标记的期望的间隔和/或定位，以及实际形成标记。提供了使用本发明装置的方法。

28. 发明申请

US20060178560A1 Endoluminal tool deployment system 审中-公开
标题翻译：腔内工具部署系统
公开(公告)号：US20060178560A1
公开(公告)日：2006-08-10
申请号：US11400120
申请日：2006-04-07
申请人： Vahid Saadat , Chris Rothe , Richard Ewers , Tracy Maahs , Kenneth Michlitsch
发明人： Vahid Saadat , Chris Rothe , Richard Ewers , Tracy Maahs , Kenneth Michlitsch
IPC分类号： A61B1/008
CPC分类号： A61B1/0055 , A61B1/018 , A61B1/2736 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/29 , A61B2017/00296 , A61B2017/003 , A61B2017/00323 , A61B2017/00827 , A61B2017/0406 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/06052 , A61B2017/2905 , A61B2017/2906 , A61B2017/306
摘要： Systems, devices and methods for endoscopic procedures are provided involving accessing and manipulating tissues beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body which has one or more independently shape-lockable sections and a variety of instruments which are either built in to the main body or advanceable through lumens which extend through the main body. Such instruments may include scopes, suction instruments, aspiration instruments, tool arms, plicators, needles, graspers, and cutters, to name a few. The ability to steer and shapelock specific sections of the main body enables access to target locations which are typically challenging to reach and provides a stabilized platform to perform a desired procedure at the target location.
摘要翻译：提供用于内窥镜手术的系统，装置和方法，其涉及访问和操纵超出传统内窥镜仪器能力的组织。该系统的实施例包括具有一个或多个独立形状可锁定部分的细长主体以及内置于主体中或通过延伸穿过主体的腔的可前进的各种仪器。这样的仪器可以包括示波器，抽吸仪器，抽吸仪器，工具臂，矫正器，针，抓取器和切割器等等。转向和塑造主体的特定部分的能力使得能够访问通常具有挑战性的目标位置，并且提供稳定的平台以在目标位置执行期望的过程。

29. 发明授权

US08262676B2 Apparatus and methods for forming gastrointestinal tissue approximations 有权
标题翻译：用于形成胃肠组织近似的装置和方法
公开(公告)号：US08262676B2
公开(公告)日：2012-09-11
申请号：US12562927
申请日：2009-09-18
申请人： Richard C. Ewers , Boris Reydel , Cang Lam , Eugene G. Chen , Brent D. Seybold , Rodney Brenneman , Vahid Saadat
发明人： Richard C. Ewers , Boris Reydel , Cang Lam , Eugene G. Chen , Brent D. Seybold , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/10 , A61B17/12 , A61B17/125
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B17/0644 , A61B17/29 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/061 , A61B2017/3445 , A61B2017/3488
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point, moving the first tissue contact point from a position initially distal to a second tissue contact point to a position proximal of the second contact point to form a tissue fold, and extending an anchor assembly through the tissue fold near the second tissue contact point.
摘要翻译：提供了设备和方法，用于通过在第一组织接触点处接合组织来形成胃肠组织折叠，将第一组织接触点从最初远端到第二组织接触点的位置移动到第二接触点的近侧的位置，以形成组织折叠，并且使锚固组件穿过第二组织接触点附近的组织褶皱延伸。

30. 发明授权

US07736372B2 Apparatus and methods for endoscopic suturing 有权
标题翻译：用于内窥镜缝合的装置和方法
公开(公告)号：US07736372B2
公开(公告)日：2010-06-15
申请号：US10986461
申请日：2004-11-10
申请人： Boris Reydel , Cang Lam , Richard C. Ewers , Rodney Brenneman , Vahid Saadat
发明人： Boris Reydel , Cang Lam , Richard C. Ewers , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/0625 , A61B2017/00353 , A61B2017/0417 , A61B2017/2927 , A61B2090/3614
摘要： Apparatus & methods for endoscopic suturing are described herein. A distal tip of the endoscopic device engages the tissue and then approximates the engaged tissue to form a tissue fold. A needle body positioned within a flexible catheter is deployed into or through the newly created tissue fold where it is then detached or released from the endoscopic device. The needle body has a length of suture which depends therefrom and can be used to secure the tissue fold. The entire endoscopic device or its tissue engaging assembly can then be rotated relative to the tissue fold while maintaining engagement with the tissue to maneuver the flexible catheter to the opposing side of the penetrated tissue fold. This procedure can be repeated any number of times to create an interrupted, continuous, or running suture to secure the tissue fold.
摘要翻译：本文描述了用于内窥镜缝合的装置和方法。内窥镜装置的远侧末端接合组织，然后近似接合的组织以形成组织折叠。定位在柔性导管内的针体部署在新产生的组织折叠中或穿过其中，然后将其从内窥镜装置分离或释放。针体具有一定长度的缝合线，该缝合线依赖于其而可用于固定组织折叠。然后，整个内窥镜装置或其组织接合组件可以相对于组织折叠旋转，同时保持与组织的接合，以将柔性导管操纵到穿透的组织折叠的相对侧。该过程可以重复任意次数以产生中断的，连续的或运行的缝线来固定组织折叠。

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