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21. 发明授权

US12017694B2 Personal shopping cart and method of use 有权
公开(公告)号：US12017694B2
公开(公告)日：2024-06-25
申请号：US18157091
申请日：2023-01-20
申请人： Jason Gardner
发明人： Jason Gardner
IPC分类号： B62B3/02 , B62B3/14 , B62B3/16
CPC分类号： B62B3/027 , B62B3/1496 , B62B3/16
摘要： A shopping cart basket comprises one or more modular baskets couplable to a bottom basket having a plurality of wheels extending downwardly to allow the shopping cart basket to roll. Each of the modular baskets has a foldable bottom wall that can act as a bottom of a separate basket or can be folded against a side wall of the modular basket. The modular baskets could be used to hold items within a smaller compartment, and can be combined with the bottom basket to form a roll-able shopping cart having a larger compartment. Such a cart is advantageously used in a store, such as a grocery store, a retail shopping mall, or a home improvement store.

22. 发明授权

US09063764B2 Automated software script creator and editor 有权
标题翻译：自动软件脚本创建者和编辑器
公开(公告)号：US09063764B2
公开(公告)日：2015-06-23
申请号：US13479862
申请日：2012-05-24
申请人： Jason Gardner
发明人： Jason Gardner
IPC分类号： G06F9/44 , G06F9/455
CPC分类号： G06F9/45508 , G06F8/30 , G06F8/33 , G06F8/36 , G06F8/71 , G06F9/45512
摘要： A method and apparatus of creating a script are enclosed. One example method of operation may provide receiving a request to load a procedure in a procedure editor application and generating a list of predetermined statements based on the loaded procedure. The example method may include receiving at least one statement selection from the list of predetermined statements and at least one specified location in the procedure and inserting the at least one selected statement into the loaded procedure at the at least one specified location.
摘要翻译：附带一个创建脚本的方法和装置。一个示例性操作方法可以提供接收在过程编辑器应用中加载过程的请求，并且基于所加载的过程生成预定语句的列表。示例性方法可以包括从预定语句的列表和过程中的至少一个指定位置接收至少一个语句选择，并且将至少一个所选择的语句插入至少一个指定位置处的加载的过程。

23. 发明申请

US20060051373A1 Particle-bound human immunodeficiency virus envelope glycoproteins and related compositions and methods 审中-公开
标题翻译：颗粒结合的人类免疫缺陷病毒包膜糖蛋白及相关组合物和方法
公开(公告)号：US20060051373A1
公开(公告)日：2006-03-09
申请号：US10510268
申请日：2002-09-06
申请人： William Olson , Norbert Schulke , Jason Gardner , Paul Maddon
发明人： William Olson , Norbert Schulke , Jason Gardner , Paul Maddon
IPC分类号： A61K39/21 , A61K39/12 , A61K38/20 , A61K38/19 , A61K31/739
CPC分类号： C07K14/005 , A61K31/739 , A61K38/162 , A61K38/193 , A61K38/195 , A61K38/20 , A61K39/12 , A61K39/21 , A61K2039/505 , A61K2039/545 , A61K2039/55511 , A61K2039/55522 , A61K2039/64 , C12N2740/16122 , C12N2740/16134 , A61K2300/00
摘要： This invention provides a first composition comprising a pharmaceutically acceptable particle and a stable HIV-1 pre-fusion envelope glycoprotein trimeric complex operably affixed thereto. This invention further provides a second composition comprising (a) a pharmaceutically acceptable particle, (b) an antigen, and (c) an agent which is operably affixed to the particle and is specifically bound to the antigen, whereby the antigen is operably bound to the particle. Finally, this invention provides related nucleic acids, vectors, cells, compositions, production methods, and prophylactic and therapeutic methods.
摘要翻译：本发明提供了包含药学上可接受的颗粒和可操作地固定于其上的稳定的HIV-1预融合包膜糖蛋白三聚体复合物的第一组合物。本发明进一步提供第二组合物，其包含（a）药学上可接受的颗粒，（b）抗原，和（c）可操作地固定在所述颗粒上且与所述抗原特异性结合的试剂，由此所述抗原可操作地结合到颗粒。最后，本发明提供了相关的核酸，载体，细胞，组合物，生产方法以及预防和治疗方法。

24. 发明申请

US20050268894A1 Paintball gun and method of operation 审中-公开
标题翻译：彩弹枪和操作方法
公开(公告)号：US20050268894A1
公开(公告)日：2005-12-08
申请号：US11203850
申请日：2005-08-15
申请人： Leon Styles , Jason Gardner
发明人： Leon Styles , Jason Gardner
IPC分类号： F41B11/00 , F41B11/26
CPC分类号： F41B11/57 , F41B11/68
摘要： An electro-pneumatically operated paint ball gun operates without the use of a mechanical sear, and includes a pneumatically-operated hammer assembly effective to bump open a discharge valve and fire the gun. A hammer member of the hammer assembly is preferably coupled for reciprocation in unison with a bolt of the paint ball gun. A method of operating the inventive paint ball gun includes pneumatic reciprocation of the hammer member and bolt in unison. The paint ball gun may include a pair of solenoid valves activated alternatingly to flow pressurized gas to the hammer assembly, and to allow an increased cyclic rate of operation for the paint ball gun.
摘要翻译：电动气动操作的油漆枪枪操作而不使用机械冲击器，并且包括气动操作的锤组件，其有效地撞击打开排出阀并起动枪。锤组件的锤构件优选地联接成与油漆球枪的螺栓一致地往复运动。操作本发明的油漆球枪的方法包括锤构件和螺栓的气动往复运动。喷枪枪可以包括一对电磁阀，其被交替地激活以将加压气体流向锤组件，并且允许喷枪滚珠枪的循环操作速率增加。

25. 发明申请

US20050266400A1 Novel sequences encoding hepatitis C virus glycoproteins 失效
标题翻译：编码丙型肝炎病毒糖蛋白的新型序列
公开(公告)号：US20050266400A1
公开(公告)日：2005-12-01
申请号：US10985205
申请日：2004-11-09
申请人： Julie Dumonceaux , Emmanuel Cormier , Jason Gardner , Tatjana Dragic
发明人： Julie Dumonceaux , Emmanuel Cormier , Jason Gardner , Tatjana Dragic
IPC分类号： A61K39/00 , C07H21/02 , C07H21/04 , C07K14/18 , C12N20060101 , C12N7/00 , C12N7/01 , C12Q1/68 , C12Q1/70
CPC分类号： C07H21/02 , A61K2039/5258 , C07H21/04 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2740/13023 , C12N2740/13043 , C12N2740/13045 , C12N2770/24222 , C12N2770/24234 , C12N2810/609 , C12Q1/707
摘要： The present invention concerns a modified nucleic acid molecule comprising a nucleotide sequence coding for a full length hepatitis C virus (HCV) glycoprotein selected from the group consisting of E1 glycoprotein and E1/E2 glycoprotein heterodimer, this molecule having at least one nucleotide alteration, wherein, due to this alteration, at least one RNA splice site selected from the group consisting of RNA splice acceptor and RNA splice donor sites is eliminated from the coding sequence. The invention is also directed to methods for expressing on the surface of a cell and a pseudovirion an HCV glycoprotein, wherein the majority of the glycoprotein is full length. The invention further provides a cell and a pseudovirion expressing such glycoprotein. The invention still further provides a method for determining whether an agent inhibits HCV fusion with and entry into a target cell. The invention also provides an agent that inhibits HCV fusion with and entry into a target cell. The invention further provides methods for treating a subject afflicted with an HCV-associated disorder, for preventing an HCV infection in a subject, and for inhibiting in a subject the onset of an HCV-associated disorder.
摘要翻译：本发明涉及一种修饰的核酸分子，其包含编码选自E1糖蛋白和E1 / E2糖蛋白异二聚体的全长丙型肝炎病毒（HCV）糖蛋白的核苷酸序列，该分子具有至少一个核苷酸改变，其中由于这种改变，从编码序列中消除了选自RNA剪接受体和RNA剪接供体位点的至少一个RNA剪接位点。本发明还涉及用于在细胞表面和假病毒表达HCV糖蛋白的方法，其中大部分糖蛋白是全长的。本发明还提供了表达这种糖蛋白的细胞和假病毒。本发明还提供了一种用于确定药物是否抑制HCV融合并进入靶细胞的方法。本发明还提供了抑制HCV融合并进入靶细胞的药剂。本发明进一步提供了治疗患有HCV相关病症的受试者，用于预防受试者中的HCV感染以及用于在受试者中抑制HCV相关病症发作的方法。

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