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21. 发明申请

US20140133004A1 WAVELENGTH SELECTION POLARIZATION CONTROLLER 有权
标题翻译：波长选择极化控制器
公开(公告)号：US20140133004A1
公开(公告)日：2014-05-15
申请号：US14126161
申请日：2012-06-12
申请人： Naoya Wada , Seitetsu Boku , Hiroyuki Yamazaki , Yusaku Tottori
发明人： Naoya Wada , Seitetsu Boku , Hiroyuki Yamazaki , Yusaku Tottori
IPC分类号： G02F1/01
CPC分类号： G02F1/0136 , G02B27/00 , G02B27/286 , G02F2203/58 , G02F2203/585
摘要： A wavelength selective polarization controller capable of controlling the polarization plane of optical wavelength multiplexing signals, for each wavelength component, and which does not generate time lag between each component is provided. This wavelength selective polarization controller has: a telecentric optical system to which optical wavelength multiplexing signals are incident; a polarization controller that controls the polarization plane of light output from the telecentric optical system; and an output optical system for outputting to an optical path output from the polarization controller. The telecentric optical system has: a first diffraction grating to which the optical wavelength multiplexing signals are incident; and a first condenser that condenses the optical wavelength multiplexing signals that have passed through the diffraction grating. The polarization controller has a plurality of phase modulators.
摘要翻译：提供一种波长选择性偏振控制器，其能够对于每个波长分量控制光波分复用信号的偏振面，并且不会在每个分量之间产生时滞。该波长选择性偏振控制器具有：光波长复用信号入射的远心光学系统; 偏振控制器，其控制从远心光学系统输出的光的偏振面; 以及用于输出到从偏振控制器输出的光路的输出光学系统。远心光学系统具有：光波长复用信号入射的第一衍射光栅; 以及冷凝已经通过衍射光栅的光波长复用信号的第一电容器。偏振控制器具有多个相位调制器。

22. 发明申请

US20070148150A1 MKK7 activation inhibitor 审中-公开
公开(公告)号：US20070148150A1
公开(公告)日：2007-06-28
申请号：US11705900
申请日：2007-02-14
申请人： Hirofumi Doi , Shinya Hosogi , Naoya Wada
发明人： Hirofumi Doi , Shinya Hosogi , Naoya Wada
IPC分类号： A61K38/54 , C12N9/99
CPC分类号： C07K14/47 , A61K38/1709 , G01N2500/00 , A61K2300/00
摘要： PAK4 and JIK, both of which bind to MKK7 and directly phosphorylate MKK7, were found in the present invention. The present invention provides an inhibitor of c-Jun phosphorylation caused by JNK3 and a method for inhibiting the same, and an agent for preventing and/or treating a disorder attributable to c-Jun phosphorylation caused by JNK3 and a method for preventing and/or treating the same, all of which comprise inhibiting one member selected from the following: the binding of PAK4 to MKK7, the phosphorylation of MKK7 by PAK4, the binding of JIK to MKK7, and the phosphorylation of MKK7 by JIK. Further, the present invention provides a method for identifying a compound that inhibits the binding of PAK4 to MKK7, the phosphorylation of MKK7 caused by PAK4, the binding of JIK to MKK7, or the phosphorylation of MKK7 caused by JIK, as well as the compound obtained thereby. Furthermore, the present invention provides a pharmaceutical composition containing an effective amount of at least one member selected from the group consisting of the aforementioned compound and the aforementioned inhibitor.

23. 发明授权

US07177544B1 Photonic network packet routing method and packet router for photonic network 有权
标题翻译：光子网络分组路由方法和光网络分组路由器
公开(公告)号：US07177544B1
公开(公告)日：2007-02-13
申请号：US09594556
申请日：2000-06-15
申请人： Naoya Wada , Hideyuki Sotobayashi , Ken-ichi Kitayama
发明人： Naoya Wada , Hideyuki Sotobayashi , Ken-ichi Kitayama
IPC分类号： H04B10/00
CPC分类号： H04Q11/0005 , H04J14/0227 , H04J14/08 , H04L45/00 , H04L45/502 , H04Q11/0066 , H04Q2011/002 , H04Q2011/0024 , H04Q2011/0039 , H04Q2011/0041 , H04Q2011/0077
摘要： A photonic network packet routing method includes the steps of optically encoding destination address information attached to an IP packet using light attributes, discriminating the encoded address information of the IP packet by optical correlation processing, switching to an output path for the IP packet based on a result of the discrimination, and outputting the IP packet labeled with prescribed address information on the output path selected by the switching step. A packet router for a photonic network includes a device for encoding by use of light attributes destination address information attached to an IP packet, a branching device for sending the IP packet having the encoded destination address information onto two paths, an address processing device for subjecting one IP packet received from the branching device to optical correlation processing and outputting a switch control signal based on a result of the discrimination, and a switch device for selectively outputting the packet by switching an output path of the other packet received from the branching device based on the address control signal from the address control device.
摘要翻译：光子网络分组路由方法包括以下步骤：使用光属性光学地编码附加到IP分组的目的地地址信息，通过光学相关处理来识别IP分组的编码地址信息，基于以下步骤切换到IP分组的输出路径判断结果，并且通过切换步骤选择的输出路径输出标有规定地址信息的IP包。用于光子网络的分组路由器包括通过使用附加到IP分组的光属性目的地地址信息进行编码的设备，用于将具有编码的目的地地址信息的IP分组发送到两个路径的分支设备，用于对从分支装置接收到的一个IP分组进行光相关处理，并且基于鉴别结果输出开关控制信号;以及开关装置，用于通过切换从分支装置接收的另一个分组的输出路径来选择性地输出分组，来自地址控制装置的地址控制信号。

24. 发明申请

US20060172360A1 Mkk7 activation inhibitor 失效
标题翻译： Mkk7激活抑制剂
公开(公告)号：US20060172360A1
公开(公告)日：2006-08-03
申请号：US10519465
申请日：2003-06-27
申请人： Hirofumi Doi , Shinya Hosogi , Naoya Wada
发明人： Hirofumi Doi , Shinya Hosogi , Naoya Wada
IPC分类号： A61K38/54 , C12Q1/48
CPC分类号： C07K14/47 , A61K38/1709 , G01N2500/00 , A61K2300/00
摘要： PAK4 and JIK, both of which bind to MKK7 and directly phosphorylate MKK7, were found in the present invention. The present invention provides an inhibitor of c-Jun phosphorylation caused by JNK3 and a method for inhibiting the same, and an agent for preventing and/or treating a disorder attributable to c-Jun phosphorylation caused by JNK3 and a method for preventing and/or treating the same, all of which comprise inhibiting one member selected from the following: the binding of PAK4 to MKK7, the phosphorylation of MKK7 by PAK4, the binding of JIK to MKK7, and the phosphorylation of MKK7 by JIK. Further, the present invention provides a method for identifying a compound that inhibits the binding of PAK4 to MKK7, the phosphorylation of MKK7 caused by PAK4, the binding of JIK to MKK7, or the phosphorylation of MKK7 caused by JIK, as well as the compound obtained thereby. Furthermore, the present invention provides a pharmaceutical composition containing an effective amount of at least one member selected from the group consisting of the aforementioned compound and the aforementioned inhibitor.
摘要翻译：在本发明中发现PAK4和JIK两者都结合MKK7并直接磷酸化MKK7。本发明提供了由JNK3引起的c-Jun磷酸化抑制剂及其抑制方法，以及用于预防和/或治疗由JNK3引起的由c-Jun磷酸化引起的病症的药剂，以及用于预防和/或所有这些都包括抑制选自以下的一种：PAK4与MKK7的结合，PAK4的MKK7的磷酸化，JIK与MKK7的结合以及通过JIK的MKK7的磷酸化。此外，本发明提供了鉴定抑制PAK4与MKK7结合的化合物，由PAK4引起的MKK7的磷酸化，JIK与MKK7的结合或由JIK引起的MKK7的磷酸化的化合物的方法，以及化合物由此获得。此外，本发明提供含有有效量的选自上述化合物和上述抑制剂中的至少一种的药物组合物。

25. 发明授权

US06876817B2 Method for routing optical packets using multiple wavelength labels, optical packet router using multiple wavelength labels, and optical packet network that uses multiple wavelength labels 失效
标题翻译：使用多个波长标签路由光分组的方法，使用多个波长标签的光分组路由器，以及使用多个波长标签的光分组网络
公开(公告)号：US06876817B2
公开(公告)日：2005-04-05
申请号：US09820647
申请日：2001-03-30
申请人： Naoya Wada , Hiroaki Harai , Wataru Chujo , Fumito Kubota
发明人： Naoya Wada , Hiroaki Harai , Wataru Chujo , Fumito Kubota
IPC分类号： H04B10/2507 , H04B10/25 , H04B10/27 , H04B10/54 , H04B10/556 , H04B10/572 , H04L12/70 , H04L12/701 , H04Q3/52 , H04Q11/00 , H04J14/02
CPC分类号： H04Q11/0005 , H04Q11/0066 , H04Q2011/002 , H04Q2011/0032 , H04Q2011/0039 , H04Q2011/0077
摘要： A method for routing optical packets using multiple wavelength labels includes converting optical packet address signals to a plurality of optical pulses having different time-deviated wavelengths by executing a first operation to impart a wavelength dependent delay time with respect to a plurality of optical pulses having different wavelengths at a same time axis position. When the optical pulses are transmitted along a predetermined optical path having dispersion, the dispersion is compensated for by executing a second operation on the optical pulses corresponding to a reverse process of the operation to impart a wavelength dependent delay time. This second operation results in the generation of a plurality of optical pulses having different wavelengths at a given point on the time axis. The pulse signals thus generated are used to determine the packet transmission route.
摘要翻译：用于使用多个波长标签路由光学分组的方法包括通过执行第一操作来将光分组地址信号转换为具有不同时间偏移波长的多个光脉冲，以便相对于具有不同波长的多个光脉冲赋予波长依赖的延迟时间波长在同一时间轴位置。当沿着具有色散的预定光路传输光脉冲时，通过对对应于操作的反向处理的光脉冲执行第二操作来赋予色散以赋予波长依赖的延迟时间来补偿色散。该第二操作导致在时间轴上的给定点产生具有不同波长的多个光脉冲。这样产生的脉冲信号用于确定分组传输路由。

26. 发明申请

US20050037449A1 Agent for controlling circadian rhythm disorder 审中-公开
标题翻译：用于控制昼夜节律紊乱的药剂
公开(公告)号：US20050037449A1
公开(公告)日：2005-02-17
申请号：US10901923
申请日：2004-07-29
申请人： Hirofumi Doi , Naoya Wada
发明人： Hirofumi Doi , Naoya Wada
IPC分类号： A61K38/00 , A61K39/00 , A61K45/00 , A61P25/00 , C12Q1/48 , G01N33/68 , C12Q1/68 , A61K31/66
CPC分类号： G01N33/6893 , C12Q1/485 , G01N2500/02
摘要： A method for controlling circadian rhythm disorders is described, characterized by inhibiting the phosphorylation of BMAL1 by c-Jun N-terminal kinase 3 (JNK3) due to the interaction between JNK3 and BMAL1; a method for preventing and/or treating diseases caused by circadian rhythm disorders; and a method for identifying a compound that inhibit phosphorylation of BMAL1 by JNK3. Also provided are: an agent for controlling circadian rhythm disorders, having the above characteristics; an agent for treating and/or preventing diseases caused by circadian rhythm disorders; a compound obtained by the identification method described above; an agent for inhibiting the phosphorylation of BMAL1 by JNK3, containing the compound; an agent for recovering the suppressed transcriptional activity of the complexes containing BMAL1 and CLOCK and for inhibiting the phosphorylation the same, containing an agent for inhibiting the expression and/or function of JNK3; and a pharmaceutical composition containing one of these.
摘要翻译：描述了一种控制昼夜节律紊乱的方法，其特征在于由于JNK3与BMAL1之间的相互作用，通过c-Jun N-末端激酶3（JNK3）抑制BMAL1的磷酸化; 用于预防和/或治疗由昼夜节律紊乱引起的疾病的方法; 以及通过JNK3鉴定抑制BMAL1磷酸化的化合物的方法。还提供：具有上述特征的用于控制昼夜节律紊乱的药剂; 用于治疗和/或预防由昼夜节律紊乱引起的疾病的药剂; 通过上述鉴定方法获得的化合物; 用于抑制含有该化合物的JNK3的BMAL1磷酸化的试剂; 用于回收含有BMAL1和CLOCK的复合物的抑制转录活性并抑制其磷酸化的试剂，其含有抑制JNK3的表达和/或功能的试剂; 和含有这些之一的药物组合物。

27. 发明授权

US09234701B2 Crushing drying device 有权
标题翻译：破碎干燥装置
公开(公告)号：US09234701B2
公开(公告)日：2016-01-12
申请号：US14125925
申请日：2012-06-14
申请人： Naoya Wada , Katsu Matsumoto , Hiroaki Kajiyama , Masuyuki Mieda , Kazuhiro Yamamoto , Natsuki Takemoto
发明人： Naoya Wada , Katsu Matsumoto , Hiroaki Kajiyama , Masuyuki Mieda , Kazuhiro Yamamoto , Natsuki Takemoto
IPC分类号： F26B17/14 , F26B25/00 , B02C13/282 , B02C13/06 , B02C13/288 , B02C23/12 , F26B1/00 , F26B17/10 , F26B17/24 , B02C13/286
CPC分类号： F26B25/001 , B02C13/06 , B02C13/282 , B02C13/288 , B02C23/12 , B02C2013/28654 , F26B1/005 , F26B17/107 , F26B17/24 , F26B2200/24
摘要： A crushing drying device includes an object-to-be-treated supply port from which an object is supplied into a main body, a crushing portion for crushing the object by hammers rotated on a drive shaft, and a classifying portion having a space for circulating the object to be treated at a position away from the crushing portion, the crushing portion has a dry gas supply port from which the heated air is supplied in a predetermined direction along an inner surface of the device main body, and the classifying portion has discharge portions from which the crushed object is discharged together with the heated air, and deviation plates for changing a flow of the object transferred to the classifying portion, so that the crushing drying device is one machine.
摘要翻译：破碎干燥装置包括：被处理物供给口，将物体从主体供给到主体;破碎部，其通过在驱动轴上旋转的锤击碎物体;破碎部，其具有循环空间; 在离开破碎部的位置处处理的物体，破碎部具有干燥气体供给口，沿着装置主体的内表面沿规定方向供给加热空气，分选部具有排出口破碎物体与加热空气一起排出的部分，以及用于改变传送到分级部分的物体的流动的偏差板，使得破碎干燥装置是一台机器。

28. 发明授权

US09146357B2 Optical fiber-based optical functional device cartridge module 有权
标题翻译：基于光纤的光功能元件盒模块
公开(公告)号：US09146357B2
公开(公告)日：2015-09-29
申请号：US14343176
申请日：2012-07-19
申请人： Naoya Wada , Tetsuya Kobayashi , Yusaku Tottori
发明人： Naoya Wada , Tetsuya Kobayashi , Yusaku Tottori
IPC分类号： G02B6/26 , G02B6/42 , G02B6/32 , G02B6/36
CPC分类号： G02B6/26 , G02B6/264 , G02B6/32 , G02B6/3616
摘要： A cartridge-type optical functional module achieves excellent optical coupling and may include an optical fiber-type module and/or a waveguide-type module. A cartridge-type optical functional module is provided that includes first and second optical fiber collimators, an optical functional object that has an optical fiber-type module or a waveguide-type module, and a base section. The optical functional object also includes a third collimator, and a first alignment mechanism for aligning the position of the third collimator in the optical functional object.
摘要翻译：盒式光学功能模块实现优异的光耦合，并且可以包括光纤型模块和/或波导型模块。提供一种盒式光学功能模块，其包括第一和第二光纤准直仪，具有光纤型模块或波导型模块的光学功能对象以及基部。光学功能物体还包括第三准直仪和用于对准光学功能对象中的第三准直仪的位置的第一对准机构。

29. 发明申请

US20150251188A1 REGENERATED CUTTING BLADE AND SHEARING TYPE GRINDER 审中-公开
标题翻译：再生切割刀片和剪切型磨床
公开(公告)号：US20150251188A1
公开(公告)日：2015-09-10
申请号：US14417344
申请日：2012-08-28
申请人： Naoya Wada , Naoki Ueno , Yasuhiko Honda , Isao Nagai
发明人： Naoya Wada , Naoki Ueno , Yasuhiko Honda , Isao Nagai
IPC分类号： B02C18/18 , B02C18/14
CPC分类号： B02C18/184 , B02C18/142 , B02C18/145
摘要： To present a regenerated cutting blade, capable of regenerating efficiently by saving the cost and labor for regenerating a cutting blade, and improved in the grinding efficiency of a shearing type grinder to be close to that of a new cutting blade, when mounted and used in a shearing type grinder, including a fixed part 125, and a blade tip 127 projecting outward from this fixed part 125, in which the blade tip 127 has a leading end edge 109 pointed toward the rotating direction, and side edges 110 on the lateral side outer periphery including the blade tip 127, the leading end edge 109 and the side edges 110 are regenerated and formed by build-up welding, and the lateral sides are provided with slip preventive build-up welding parts 111, 112, 113 of the workpiece extending from the side edges 110 toward the central side of its rotation or the central direction, being formed by three regenerating processes.
摘要翻译：为了提供能够通过节省用于再生切割刀片的成本和劳动力而有效地再生的再生切割刀片，并且将剪切式研磨机的研磨效率提高为接近于新的切割刀片的磨削效率，当安装和使用时包括固定部分125的剪切式研磨机以及从该固定部125向外突出的叶片尖端127，其中叶片尖端127具有朝向旋转方向指向的前端边缘109，侧面侧的侧边缘110 包括叶片尖端127，前端缘109和侧边缘110的外周边通过堆积焊接再生和形成，并且侧边设置有工件的防滑成型焊接部111,112,113 从侧边缘110向其旋转中心方向或中心方向延伸，由三个再生过程形成。

30. 发明申请

US20150204373A1 DETACHING METHOD OF FILLING MEMBER AND FILLING MEMBER USED THEREIN AND CUTTER BLADE USING THIS FILLING MEMBER 审中-公开
标题翻译：使用该填充构件填充构件和填充构件的切割方法和切割刀片
公开(公告)号：US20150204373A1
公开(公告)日：2015-07-23
申请号：US14382430
申请日：2012-03-07
申请人： Naoya Wada , Akira Sugimoto , Kazufumi Sakata
发明人： Naoya Wada , Akira Sugimoto , Kazufumi Sakata
IPC分类号： F16B39/02
CPC分类号： F16B39/021 , B02C18/18 , F16B37/14 , Y10T29/49815
摘要： To present a detaching method of a filling member and a filling member to be used therein in which the filling member loaded in a space of a counterbore hole or a hole of a bolt head may be detached easily if required to remove the bolt, for the ease of repair or replacement, a prepared hole is made in a filling member 3 by means of a drill D, and female threads 31 are formed in the filling member by tapping process, and an extracting force is applied to the filling member by way of the female threads 31 engaged with the rotating tap T, so that the filling member 3 can be pulled out of the space of the counterbore hole 2.
摘要翻译：为了提出一种用于其中的填充构件和填充构件的拆卸方法，其中如果需要拆卸螺栓，则可以容易地拆卸装载在钻孔的空间中的填充构件或螺栓头的孔的填充构件，容易的修理或更换，通过钻头D在填充构件3中制备预制孔，并且通过攻丝工艺在填充构件中形成内螺纹31，并且通过以下方式将填充构件施加提取力：内螺纹31与旋转分接头T接合，使得填充构件3能够从沉孔2的空间中拉出。

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