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21. 发明授权

US08575142B2 Agent for improving insulin resistance 有权
标题翻译：改善胰岛素抵抗的药物
公开(公告)号：US08575142B2
公开(公告)日：2013-11-05
申请号：US11917870
申请日：2006-09-22
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A61K31/575 , A61K47/00 , C07J9/00
CPC分类号： A61K36/896 , A23L33/105 , A23V2002/00 , A61K31/575 , A61K36/899 , A23V2250/21 , A23V2200/328
摘要： To inhibit production of adipocytokines, in particular, adipocytokines that elicit insulin resistance and to prevent onset of pathosis caused by the insulin resistance or ameliorate the pathosis, the present invention provides an agent or a food or drink which contains a compound having a lophenol skeleton, or an organic solvent extract or a hot water extract of a Liliaceae plant or, a fraction thereof containing the compound as an active ingredient.
摘要翻译：为了抑制脂肪细胞因子的产生，特别是引起胰岛素抵抗并抑制由胰岛素抵抗引起的病变发作或改善病变的脂肪细胞因子，本发明提供了含有具有洛芬骨架的化合物的药剂或食品或饮料，或百合科植物的有机溶剂提取物或热水提取物，或其含有该化合物作为活性成分的级分。

22. 发明授权

US07846905B2 Agent for inhibiting visceral fat accumulation 有权
标题翻译：抑制内脏脂肪积累的药剂
公开(公告)号：US07846905B2
公开(公告)日：2010-12-07
申请号：US11913022
申请日：2006-09-21
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A01N45/00 , A61K9/00 , A61K36/00
CPC分类号： C07J17/00 , A23L2/52 , A23L33/105 , A61K31/704 , A61K36/896
摘要： To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity considered to be a main factor of metabolic syndrome, there is provided an agent or a food or drink, including as an active ingredient 3-O-β-D-glucopyranosyl-4-methylergost-7-en-3-ol, an organic solvent extract, a hot water extract, a squeezed liquid of a Liliaceae plant or a fraction thereof which contains the compound.
摘要翻译：为了减少在腹腔中积累的脂肪的量并且预防或改善被认为是代谢综合征的主要因素的内脏脂肪型肥胖，提供了一种试剂或食品或饮料，包括作为活性成分的3-O- D-吡喃葡萄糖基-4-甲基麦角-7-烯-3-醇，有机溶剂提取物，热水提取物，百合科植物的挤压液或其含有该化合物的级分。

23. 发明授权

US08093233B2 Agent for inhibiting visceral fat accumulation 有权
标题翻译：抑制内脏脂肪积累的药剂
公开(公告)号：US08093233B2
公开(公告)日：2012-01-10
申请号：US11913758
申请日：2006-09-21
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A61K31/56 , C07J43/00
CPC分类号： A61K36/896 , A23L33/105 , A23L33/30 , A61K31/575 , C07J9/00
摘要： To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity, considered to be a main factor of metabolic syndrome, the present invention provides an agent or a food or drink which contains a compound having a lophenol skeleton, or an organic solvent extract or a hot water extract of a Liliaceae plant, or a fraction thereof containing the compound is used as an active ingredient.
摘要翻译：为了减少在腹腔中积累的脂肪的量并且被认为是代谢综合征的主要因素的内脏脂肪型肥胖症，本发明提供了含有具有薄荷骨架的化合物的药剂或食品或饮料，或使用百合科植物的有机溶剂提取物或热水提取物或其含有该化合物的级分作为活性成分。

24. 发明授权

US07947669B2 Agent for improving insulin resistance 有权
标题翻译：改善胰岛素抵抗的药物
公开(公告)号：US07947669B2
公开(公告)日：2011-05-24
申请号：US12064607
申请日：2006-09-22
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A61K31/56 , A61K33/00
CPC分类号： A61K36/896 , A23L33/105 , A23V2002/00 , A61K31/575 , A61K31/704 , A61K36/899 , C07J17/00 , C07J53/00 , A23V2250/21 , A23V2200/328
摘要： To inhibit production of adipocytokines, in particular, adipocytokines that elicit insulin resistance and to prevent onset of pathosis caused by the insulin resistance, or improve the pathosis, the present invention provides an agent or a food or drink which contains a compound having a cyclolanostane skeleton, or an organic solvent extract, a hot water extract of a plant of the family Liliaceae or Gramineae, or a fraction thereof which contains the compound as an active ingredient.
摘要翻译：为了抑制脂肪细胞因子的产生，特别是引起胰岛素抵抗和预防由胰岛素抵抗引起的病变发作或改善病变的脂肪细胞因子，本发明提供了含有具有环氨基苯甲酸骨架的化合物的药剂或食品或饮料或有机溶剂提取物，百合科或禾本科植物的热水提取物，或其部分含有该化合物作为活性成分。

25. 发明申请

US20100286104A1 AGENT FOR INHIBITING VISCERAL FAT ACCUMULATION 有权
标题翻译：用于抑制粘性脂肪蓄积的代理
公开(公告)号：US20100286104A1
公开(公告)日：2010-11-11
申请号：US12841076
申请日：2010-07-21
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A61K31/575 , A61P3/04
CPC分类号： A61K36/896 , A23L33/105 , A23L33/30 , A61K31/575 , C07J9/00
摘要： To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity, considered to be a main factor of metabolic syndrome, the present invention provides an agent or a food or drink which contains a compound having a lophenol skeleton, or an organic solvent extract or a hot water extract of a Liliaceae plant, or a fraction thereof containing the compound as an active ingredient.
摘要翻译：为了减少在腹腔中积累的脂肪的量并且被认为是代谢综合征的主要因素的内脏脂肪型肥胖症，本发明提供了含有具有薄荷骨架的化合物的药剂或食品或饮料，或百里香科植物的有机溶剂提取物或热水提取物，或其含有该化合物作为活性成分的部分。

26. 发明授权

US07812012B2 Agent for inhibiting visceral fat accumulation 有权
公开(公告)号：US07812012B2
公开(公告)日：2010-10-12
申请号：US11913758
申请日：2006-09-21
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A61K31/56 , C07J1/00
摘要： To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity, considered to be a main factor of metabolic syndrome, the present invention provides an agent or a food or drink which contains a compound having a lophenol skeleton, or an organic solvent extract or a hot water extract of a Liliaceae plant, or a fraction thereof containing the compound is used as an active ingredient.

27. 发明申请

US20100035851A1 AGENT FOR IMPROVING INSULIN RESISTANCE 有权
标题翻译：改善胰岛素抵抗的药剂
公开(公告)号：US20100035851A1
公开(公告)日：2010-02-11
申请号：US12064607
申请日：2006-09-22
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： A61K31/56 , C07J53/00
CPC分类号： A61K36/896 , A23L33/105 , A23V2002/00 , A61K31/575 , A61K31/704 , A61K36/899 , C07J17/00 , C07J53/00 , A23V2250/21 , A23V2200/328
摘要： To inhibit production of adipocytokines, in particular, adipocytokines that elicit insulin resistance and to prevent onset of pathosis caused by the insulin resistance, or improve the pathosis, the present invention provides an agent or a food or drink which contains a compound having a cyclolanostane skeleton, or an organic solvent extract, a hot water extract of a plant of the family Liliaceae or Gramineae, or a fraction thereof which contains the compound as an active ingredient.
摘要翻译：为了抑制脂肪细胞因子的产生，特别是引起胰岛素抵抗和预防由胰岛素抵抗引起的病变发作或改善病变的脂肪细胞因子，本发明提供了含有具有环氨基苯甲酸骨架的化合物的药剂或食品或饮料或有机溶剂提取物，百合科或禾本科植物的热水提取物，或其部分含有该化合物作为活性成分。

28. 发明申请

US20090093450A1 AGENT FOR INHIBITING VISCERAL FAT ACCUMULATION 有权
标题翻译：用于抑制粘性脂肪蓄积的代理
公开(公告)号：US20090093450A1
公开(公告)日：2009-04-09
申请号：US11913758
申请日：2006-09-21
申请人： Miyuki Tanaka , Eriko Misawa
发明人： Miyuki Tanaka , Eriko Misawa
IPC分类号： C07J9/00 , A61K31/56 , A61P3/00
CPC分类号： A61K36/896 , A23L33/105 , A23L33/30 , A61K31/575 , C07J9/00
摘要： To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity, considered to be a main factor of metabolic syndrome, the present invention provides an agent or a food or drink which contains a compound having a lophenol skeleton, or an organic solvent extract or a hot water extract of a Liliaceae plant, or a fraction thereof containing the compound is used as an active ingredient.
摘要翻译：为了减少在腹腔中积累的脂肪的量并且被认为是代谢综合征的主要因素的内脏脂肪型肥胖症，本发明提供了含有具有薄荷骨架的化合物的药剂或食品或饮料，或使用百合科植物的有机溶剂提取物或热水提取物或其含有该化合物的级分作为活性成分。

29. 发明申请

US20120294913A1 METHOD FOR MANUFACTURING ALOE POWDER 审中-公开
标题翻译：制造粉末的方法
公开(公告)号：US20120294913A1
公开(公告)日：2012-11-22
申请号：US13514150
申请日：2010-11-11
申请人： Yuzo Asano , Kouji Nomaguchi , Muneo Yamada , Miyuki Tanaka
发明人： Yuzo Asano , Kouji Nomaguchi , Muneo Yamada , Miyuki Tanaka
IPC分类号： A61K8/02 , A23L1/28 , A61K36/886 , A61Q19/00 , A61K9/14 , A61K8/97
CPC分类号： A23L2/52 , A23K10/30 , A23K20/10 , A23L19/01 , A23L33/105 , A61K8/022 , A61K8/97 , A61K36/886 , A61Q19/00
摘要： A technique for efficiently performing pulverization of a dried aloe gel using an air flow type mill is provided. 1) A dried aloe gel is treated by supercritical extraction, an extract is removed from the dried aloe gel to obtain an extraction residue, and then 2) the extraction residue is pulverized with an air flow type mill to produce an aloe powder.
摘要翻译：提供了使用气流式粉碎机有效地进行干燥的芦荟凝胶粉碎的技术。 1）通过超临界萃取处理干芦荟凝胶，从干燥的芦荟凝胶中除去提取物，得到提取残渣，然后用空气流式研磨机粉碎提取残渣，制成芦荟粉末。

30. 发明授权

US08877265B2 Method of producing aloe vera extract 有权
标题翻译：生产芦荟提取物的方法
公开(公告)号：US08877265B2
公开(公告)日：2014-11-04
申请号：US12840122
申请日：2010-07-20
申请人： Miyuki Tanaka , Muneo Yamada
发明人： Miyuki Tanaka , Muneo Yamada
IPC分类号： A61K36/886 , A61K31/575 , A23L1/30 , A61K31/58
CPC分类号： A61K31/58 , A23L33/105 , A23V2002/00 , A61K31/575 , A61K36/886 , A23V2250/2102 , A23V2200/326
摘要： The present invention provides: an Aloe vera extract that can be safely ingested, can be used as a material of food for preventing lifestyle diseases, contains an extremely low level of an anthraquinone (anthraquinone-based compound), and can be added to foods; and a method of producing the Aloe vera extract. A supercritical fluid extraction method can produce an Aloe vera extract containing a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more and having the following properties (1) and/or (2): (1) the mass mixing ratio of the cyclolanostane compound and lophenol compound is as follows: cyclolanostane compound:lophenol compound=6.3:2.7 to 5.1:4.9; and/or (2) the content of an anthraquinone-based compound is 0.001% by mass or less.
摘要翻译：本发明提供：可以安全摄取的芦荟提取物，可以用作防止生活方式疾病的食品的材料，含有极低水平的蒽醌（蒽醌类化合物），可以添加到食品中; 以及生产芦荟提取物的方法。超临界流体萃取法可以生产含有1.0质量％以上的环烷基苯化合物和苯酚化合物的混合物的芦荟提取物，具有以下性质（1）和/或（2）：（ 1）环氨基苯烷化合物和苯酚化合物的质量混合比如下：环丁烷化合物：苯酚化合物= 6.3:2.7〜5.1:4.9; 和/或（2）基于蒽醌的化合物的含量为0.001质量％以下。

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