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21. 发明授权

US5170177A Method of operating an ink jet to achieve high print quality and high print rate 失效
标题翻译：操作喷墨以实现高打印质量和高打印率的方法
公开(公告)号：US5170177A
公开(公告)日：1992-12-08
申请号：US807777
申请日：1991-12-10
申请人： Douglas M. Stanley , Joy Roy , Susan C. Schoening , Jeffrey J. Anderson
发明人： Douglas M. Stanley , Joy Roy , Susan C. Schoening , Jeffrey J. Anderson
IPC分类号： B41J2/015 , B41J2/045 , B41J2/21
CPC分类号： B41J2/04516 , B41J2/04581 , B41J2/04588 , B41J2/2128 , B41J2002/14387
摘要： A drop-on-demand ink jet has an ink chamber coupled to a source of ink, and an ink drop orifice with an outlet. An acoustic driver produces a pressure wave in the ink and causes the ink to pass outwardly through the ink drop orifice and outlet. The driver is driven with bipolar drive pulses having a refill pulse component and an eject pulse component of a polarity which is opposite to the refull pulse component. The refill and eject pulse components are separated by a wait period. The drive pulses may be adjusted to minimize their energy content at a frequency corresponding to the dominant acoustic resonance frequency of the ink jet. This will accelerate drop breakoff, optimize drop shape and minimize drop speed variations over the range of drop printing rates. The ink jet printer of the present invention may be used to print with a wide variety of inks, including phase change inks to achieve high print quality at high print rates.
摘要翻译：按需喷墨喷墨具有联接到墨源的墨室和具有出口的墨滴孔。声学驱动器在油墨中产生压力波，并使油墨通过墨滴孔和出口向外通过。驱动器由具有与补偿脉冲成分相反的极性的补充脉冲成分和弹出脉冲成分的双极驱动脉冲驱动。补充和排出脉冲组件在等待期间分开。可以调节驱动脉冲以在与喷墨的主要声共振频率相对应的频率下最小化其能量含量。这将加速掉落分离，优化液滴形状并最大限度地降低液滴速度的变化范围。本发明的喷墨打印机可用于使用各种各样的油墨进行打印，包括相变油墨以在高打印速率下实现高打印质量。

22. 发明申请

US20130078733A1 SYSTEMS AND METHODS FOR FLUID HANDLING 有权
标题翻译：流体处理系统与方法
公开(公告)号：US20130078733A1
公开(公告)日：2013-03-28
申请号：US13244952
申请日：2011-09-26
申请人： Elizabeth Holmes , Joy Roy , John Kent Frankovick
发明人： Elizabeth Holmes , Joy Roy , John Kent Frankovick
IPC分类号： G01N1/00 , B01L3/02
CPC分类号： B01L3/50825 , B01L3/0217 , B01L3/5021 , B01L3/523 , B01L7/52 , B01L9/06 , B01L2200/028 , B01L2200/0631 , B01L2200/0647 , B01L2200/0684 , B01L2200/0689 , B01L2200/082 , B01L2200/141 , B01L2200/16 , B01L2300/044 , B01L2300/0829 , B01L2400/0409 , B01L2400/043 , B01L2400/0677 , G01N35/00 , G01N35/1072 , G01N2035/00277 , Y10T436/25
摘要： Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.
摘要翻译：提供系统和方法用于样品处理。可以提供能够接收样品并执行样品制备，样品测定和检测步骤中的一种或多种的装置。该装置可能能够进行多个测定。该装置可以包括一个或多个可以执行样品制备，样品测定和检测步骤中的一个或多个的模块。该装置可以能够使用小体积的样品来执行步骤。

23. 发明授权

US06514704B2 Quality control mechanism and process for a biofluid multi-ejector system 失效
公开(公告)号：US06514704B2
公开(公告)日：2003-02-04
申请号：US09773804
申请日：2001-02-01
申请人： Richard H. Bruce , Scott A. Elrod , Babur B. Hadimioglu , David A. Horine , Jaan Noolandi , Joy Roy , Robert A. Sprague
发明人： Richard H. Bruce , Scott A. Elrod , Babur B. Hadimioglu , David A. Horine , Jaan Noolandi , Joy Roy , Robert A. Sprague
IPC分类号： C12Q168
CPC分类号： G01N35/10 , G01N35/00712 , G01N35/1009 , G01N2035/1037 , G06F19/00
摘要： A method and mechanism for ensuring quality control in printed biological assays is provided. A multi-ejector system having a plurality of individual drop ejectors is loaded with a variety of biofluids. Biofluids include at least a carrier fluid, a biological material to be used in the testing, and markers, such as fluorescent dyes. Data regarding the biofluid loaded in each of the drop ejectors is stored along with an expected signature output of the biofluid. Particularly, the signature output represents signals from individual ones of the fluorescent markers included within the biofluid. Once a biological assay consisting of the biofluid drops has been printed, a scanner capable of detecting the markers scans the biological assay and obtains signature output signals for each of the drops of the biological assay. A comparing operation is undertaken to compare the obtained signature output through the scanning operation, with the expected signature output signals for the biofluid loaded in the corresponding drop ejector. The biological material itself may also be tagged with a marker to ensure its inclusion in the biofluid. By the comparing operation, it is possible to verify the biofluids were loaded in the proper drop ejector, including the proper biological material, and that the drop ejectors are functioning properly.

24. 发明授权

US06336699B1 Self-cleaning wet wipe method and apparatus for cleaning orifices in an AIP type printhead 有权
标题翻译：自清洁湿擦拭方法和AIP型打印头清洗孔的设备
公开(公告)号：US06336699B1
公开(公告)日：2002-01-08
申请号：US09448008
申请日：1999-11-23
申请人： Shahin Sarkissian , Joy Roy
发明人： Shahin Sarkissian , Joy Roy
IPC分类号： B41J2165
CPC分类号： B41J2/16538 , B41J2/16552
摘要： In order to clean a dirty printhead, the dirty printhead is first capped and the ink pressure in the printhead increased significantly to allow ink to escape through the orifices and completely fill a small gap inside the cap portion. After letting the orifices soak for a predetermined time to dissolve the dried ink and loosen dust debris which may be found on the printheads, the cap drainhole is opened to drain the ink while keeping the ink pressure inside the head at an intermediate higher level. Dirty ink remaining inside the orifice bore is removed using a self cleaning wiping station in separate steps. During a first step, the wiping element is pressed into contact with the orifices. The dirty ink, because of the high pressure inside the printhead, is unable to reenter the printhead and is absorbed by the wiping element. In a second step, the pressure inside the printhead is decreased significantly below operating pressures to enable the menisci to retreat inside an orifice lip. Then the orifices are again wiped with another portion of the wiping element to remove any remaining ink and to assist in drying the printhead. Once the printhead has been cleaned, the wiping station is moved out of engagement with the printhead and the wiping station automatically cleans the wiping element by passing the wiping element through the washing fluid and the squeegee element until absorbed ink is removed from the wiping element.
摘要翻译：为了清洁脏的打印头，脏的打印头首先被盖住，并且打印头中的墨水压力显着增加，从而允许墨水通过孔排出并完全填充盖部分内的小间隙。在使孔口浸泡预定时间以溶解干燥的油墨并松开打印头上可能发现的灰尘碎屑之后，打开帽排水孔以排出油墨，同时将头部内的油墨压力保持在较高水平。在单独的步骤中使用自清洁擦拭站去除留在孔口内的脏墨。在第一步骤中，擦拭元件被压接与孔口接触。由于打印头内部的高压，脏的墨水不能重新进入打印头并被擦拭元件吸收。在第二步骤中，打印头内部的压力明显地降低到工作压力以下，以使得弯液面能够在孔唇口内退缩。然后再次用擦拭元件的另一部分擦拭孔口以除去任何剩余的油墨并有助于干燥打印头。一旦打印头被清洁，擦拭站就脱离与打印头的接合，并且擦拭站通过使擦拭元件通过洗涤流体和刮板元件自动清洁擦拭元件，直到从擦拭元件移除吸收的墨。

25. 发明授权

US6154236A Acoustic ink jet printhead design and method of operation utilizing flowing coolant and an emission fluid 有权
标题翻译：声喷墨打印头设计和使用流动的冷却剂和排放流体的操作方法
公开(公告)号：US6154236A
公开(公告)日：2000-11-28
申请号：US361039
申请日：1999-07-23
申请人： Joy Roy , Babur B. Hadimioglu
发明人： Joy Roy , Babur B. Hadimioglu
IPC分类号： B41J2/14 , B41J2/135 , B41J2/05
CPC分类号： B41J2/14008 , B41J2/14
摘要： A droplet emitter with an array of droplet emitting devices constructed such that one flowing liquid is used to create the droplets while a second low acoustic impedance liquid can be used to both make the transfer of acoustic energy to the first liquid more efficient and help maintain a uniform temperature of the droplet emitter array. Both liquids can be circulated through the droplet emitter to allow for excess heat generated by control electronics to be transferred to the flowing liquids. This prevents, for instance excess heat build-up within the droplet emitter and allows for higher more accurate droplet emission rates.
摘要翻译：具有液滴发射装置的阵列的液滴发射器被构造成使得一个流动的液体被用于产生液滴，而第二低声阻抗液体可以用于使声能量转移到第一液体更有效并且有助于维持液滴发射器阵列的均匀温度。这两种液体都可以通过液滴发射器循环，以使控制电子产生的多余的热量转移到流动的液体中。这防止了例如液滴发射器内的过多的热积聚并且允许更高精度的液滴排放速率。

26. 发明授权

US5087930A Drop-on-demand ink jet print head 失效
标题翻译： DROP-ON-DEMAND INK喷墨打印头
公开(公告)号：US5087930A
公开(公告)日：1992-02-11
申请号：US430213
申请日：1989-11-01
申请人： Joy Roy , John S. Moore
发明人： Joy Roy , John S. Moore
IPC分类号： B41J2/045 , B41J2/055 , B41J2/14 , B41J2/155 , B41J2/16
CPC分类号： B41J2/155 , B41J2002/14387 , B41J2002/14419 , B41J2202/12
摘要： An extremely compact ink jet print head has an array of closely spaced nozzles which are supplied from densely packed ink pressure chambers by way of offset channels. The ink supply inlets leading to the pressure chambers and the offset channels are designed to provide uniform operating characteristics to the ink jet nozzles of the array. To enhance the packing density of the pressure chambers, the ink supply channels leading to the pressure chambers and offset channels are positioned in planes between the pressure chambers and nozzles. An optional ink purging pathway is provided for purging bubbles and other contaminants from the chamber side of the nozzles. The ink jet print head may be assembled from plural plates with features in all but the nozzle defining plate being formed by photo-patterning and etching processes without requiring machining or other metal working.

27. 发明授权

US4728969A Air assisted ink jet head with single compartment ink chamber 失效
标题翻译：空气辅助喷墨头与单室墨水室
公开(公告)号：US4728969A
公开(公告)日：1988-03-01
申请号：US884845
申请日：1986-07-11
申请人： Hue P. Le , Joy Roy , Ronald L. Adams , James C. Oswald , Jeffery J. Anderson
发明人： Hue P. Le , Joy Roy , Ronald L. Adams , James C. Oswald , Jeffery J. Anderson
IPC分类号： B41J2/045 , B41J2/04 , B41J2/14 , G01D15/18
CPC分类号： B41J2/14298 , B41J2/04 , B41J2002/14387 , B41J2202/02
摘要： An air-assisted drop-on-demand ink jet head 10 has a single compartment ink chamber 14 and is designed for operation over a wide range of ink drop repetition rates, including extremely high repetition rates, such as twenty kilohertz. The components included in the ink jet head have natural resonance frequencies which are greater than the desired maximum drop generation frequency of the ink jet head. In addition, the natural frequency of each of the components of the ink jet head are sufficiently different from one another to prevent intercoupling. Ink is supplied to the ink chamber 14 via a supply inlet passageway 38 which has a cross-sectional area which is sized large enough to allow the supply of ink to the ink chamber. Yet, this area is small enough so that the natural frequencies of ink in the ink inlet do not significantly alter drop generating pressure pulses in the ink chamber 14.
摘要翻译：空气辅助按需喷墨头10具有单室墨水室14，并且被设计用于在广泛的墨滴重复率下操作，包括极高的重复率，例如二十千赫兹。包括在喷墨头中的部件具有大于喷墨头的期望的最大液滴产生频率的天然共振频率。此外，喷墨头的每个部件的固有频率彼此充分地不同，以防止互耦。墨水通过供给入口通道38供应到墨室14，供应入口通道38的横截面面积大到足以允许向墨水室供应墨水。然而，该区域足够小，使得墨水入口中的油墨的固有频率不会显着改变墨水室14中产生的压力脉冲。

28. 发明授权

US09664702B2 Fluid handling apparatus and configurations 有权
公开(公告)号：US09664702B2
公开(公告)日：2017-05-30
申请号：US13244950
申请日：2011-09-26
申请人： Elizabeth Holmes , Joy Roy
发明人： Elizabeth Holmes , Joy Roy
IPC分类号： B01L3/02 , G01N33/53 , G01N35/00 , G01N35/10 , G01N30/88
CPC分类号： G01N35/0092 , B01L3/0279 , G01N35/1065 , G01N2030/8827 , G01N2035/00326 , G01N2035/103 , G01N2035/1048
摘要： Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

29. 发明授权

US08475739B2 Systems and methods for fluid handling 有权
标题翻译：流体处理系统和方法
公开(公告)号：US08475739B2
公开(公告)日：2013-07-02
申请号：US13244952
申请日：2011-09-26
申请人： Elizabeth Holmes , Joy Roy , John Kent Frankovich
发明人： Elizabeth Holmes , Joy Roy , John Kent Frankovich
IPC分类号： B01L3/02
CPC分类号： B01L3/50825 , B01L3/0217 , B01L3/5021 , B01L3/523 , B01L7/52 , B01L9/06 , B01L2200/028 , B01L2200/0631 , B01L2200/0647 , B01L2200/0684 , B01L2200/0689 , B01L2200/082 , B01L2200/141 , B01L2200/16 , B01L2300/044 , B01L2300/0829 , B01L2400/0409 , B01L2400/043 , B01L2400/0677 , G01N35/00 , G01N35/1072 , G01N2035/00277 , Y10T436/25
摘要： Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.
摘要翻译：提供系统和方法用于样品处理。可以提供能够接收样品并执行样品制备，样品测定和检测步骤中的一种或多种的装置。该装置可能能够进行多个测定。该装置可以包括一个或多个可以执行样品制备，样品测定和检测步骤中的一个或多个的模块。该装置可以能够使用小体积的样品来执行步骤。

30. 发明授权

US06713022B1 Devices for biofluid drop ejection 有权
标题翻译：生物流体液滴喷射装置
公开(公告)号：US06713022B1
公开(公告)日：2004-03-30
申请号：US09724987
申请日：2000-11-22
申请人： Jaan Noolandi , David A. Horine , Babur B. Hadimioglu , Richard H. Bruce , Joy Roy , Scott A. Elrod
发明人： Jaan Noolandi , David A. Horine , Babur B. Hadimioglu , Richard H. Bruce , Joy Roy , Scott A. Elrod
IPC分类号： B41J2175
CPC分类号： B01L3/0268 , B01L2400/0439 , G01N35/1002 , G01N2035/102 , G01N2035/1041
摘要： A biofluid drop ejection unit for ejecting biofluid drops. A biofluid drop ejection mechanism of such a unit includes a transducer, which generates energy used to emit the biofluid drop. Further provided is a reagent cartridge or biofluid containment area which holds the biofluid. The reagent cartridge or biofluid containment area is configured to hold low volumes of biofluid and to avoid contamination of the biofluid. The reagent cartridge or biofluid containment area is in operational connection with the drop ejection mechanism such that upon operation of the drop ejection mechanism, biofluid drops are emitted. The biofluid drop ejection mechanism is a high efficiency device, and may be configured as two separate pieces or as a single disposable unit.
摘要翻译：用于喷射生物流体滴的生物流体滴落喷射单元。这种单元的生物流体液滴喷射机构包括换能器，其产生用于发射生物流体滴的能量。另外还提供了一个保持生物流体的试剂盒或生物流体容纳区域。试剂盒或生物流体容纳区域被配置为保持低体积的生物流体并避免污染生物流体。试剂盒或生物流体容纳区域与液滴喷射机构操作连接，使得在液滴喷射机构的操作时，发射生物流体液滴。生物流体液滴喷射机构是高效率的装置，并且可以被配置为两个分开的部件或者作为单个一次性部件。

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