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21. 发明授权

US06230714B1 Cardiac constraint with prior venus occlusion methods 有权
标题翻译：心脏约束与先前的金星闭塞
公开(公告)号：US06230714B1
公开(公告)日：2001-05-15
申请号：US09193260
申请日：1998-11-18
申请人： Clifton A. Alferness , Donald F. Palme , James Edward Shapland
发明人： Clifton A. Alferness , Donald F. Palme , James Edward Shapland
IPC分类号： A61B1900
CPC分类号： A61F2/2481 , A61B17/12036 , A61B17/12109 , A61B17/12122 , A61B17/12136
摘要： A method for treating cardiac disease includes accessing a heart and restricting a blood supply to the heart to reduce a size of the heart. A constraining device is placed on the heart. The constraining device is secured to the heart with the constraining device having portions disposed on opposite sides of the heart to constrain circumferential expansion of the heart during diastole and permit unimpeded contraction of the heart during systole. Access to the heart is closed while leaving the constraining device in place on the heart.
摘要翻译：治疗心脏病的方法包括进入心脏并限制对心脏的血液供应以减小心脏的大小。约束装置置于心脏上。约束装置固定在心脏上，约束装置具有设置在心脏的相对侧上的部分，以在舒张期期间约束心脏的周向扩张，并允许收缩期间心脏不受阻碍的收缩。使心脏闭合，同时将约束装置留在心脏上。

22. 发明授权

US08708986B2 Collection catheter and kit 有权
标题翻译：收集导管和试剂盒
公开(公告)号：US08708986B2
公开(公告)日：2014-04-29
申请号：US12584991
申请日：2009-09-14
申请人： James Edward Shapland , Tuan Miuh Doan , Mark Francis Brown
发明人： James Edward Shapland , Tuan Miuh Doan , Mark Francis Brown
IPC分类号： A61M1/00 , A61M1/36 , A61M25/10
CPC分类号： A61M1/0035 , A61M1/0031 , A61M1/3627 , A61M1/3653 , A61M1/3659 , A61M25/007 , A61M25/1002 , A61M2025/0031 , A61M2025/1052 , A61M2025/1093 , A61M2025/1095
摘要： A catheter for collecting fluid such as blood from a vessel such as a coronary sinus of a patient has an elongated, flexible tubular portion and an annular sealing member spaced from a distal end of the tubular member. A proximal end of the tubular member is adapted to be connected to a source of suction for applying suction to a collection lumen of the tubular member. The distal end is placed in a blood vessel with the sealing member spaced from opposing surface of the vessel in an absence of a suction applied to the collection lumen. Suction is applied to the collection lumen in an amount sufficient to draw blood from the vessel through the fluid inlet and into the collection lumen and further sufficient to urge the opposing surface of the vessel to migrate into sealing engagement with the sealing member.
摘要翻译：用于从诸如患者的冠状窦的容器收集诸如血液的流体的导管具有细长的柔性管状部分和与管状构件的远端间隔开的环形密封构件。管状构件的近端适于连接到用于向管状构件的收集腔施加吸力的抽吸源。远端被放置在血管中，其中密封构件在没有施加到收集腔的抽吸的情况下与容器的相对表面间隔开。以足以将血液从血管通过流体入口吸入并进入收集腔并进一步足以促使血管的相对表面迁移到与密封构件密封接合的量施加到收集腔。

23. 发明授权

US08617051B2 Cardiac support device delivery tool with release mechanism 有权
标题翻译：带释放机构的心脏支持装置输送工具
公开(公告)号：US08617051B2
公开(公告)日：2013-12-31
申请号：US13524093
申请日：2012-06-15
申请人： Aaron J. Hjelle , James Edward Shapland , Michael Andreini , Dan Titcomb , Jeffrey Popowski , Bradley Knippel
发明人： Aaron J. Hjelle , James Edward Shapland , Michael Andreini , Dan Titcomb , Jeffrey Popowski , Bradley Knippel
IPC分类号： A61F2/00
CPC分类号： A61F2/2481 , A61F2002/2484
摘要： An apparatus for placing a cardiac support device (CSD) on a heart. The apparatus includes a body, a deployment mechanism on the body for supporting the CSD in an open position for placement on the heart, and a release mechanism coupled to the deployment mechanism for releasably mounting the CSD to the deployment mechanism. The release mechanism includes a release element for releasably engaging the CSD, and a release actuator coupled to the release element for actuating the release element to release the CSD.
摘要翻译：用于将心脏支持装置（CSD）放置在心脏上的装置。该装置包括主体，主体上用于将CSD支撑在打开位置以便放置在心脏上的展开机构，以及联接到展开机构的释放机构，用于可释放地将CSD安装到展开机构。释放机构包括用于可释放地接合CSD的释放元件和联接到释放元件的释放致动器，用于致动释放元件以释放CSD。

24. 发明授权

US08292871B2 Regional cardiac tissue treatment 有权
标题翻译：区域心脏组织治疗
公开(公告)号：US08292871B2
公开(公告)日：2012-10-23
申请号：US12799007
申请日：2010-04-14
申请人： James Edward Shapland , Tuan Minh Doan , David Martin Kaye , Adam Lucas Bilney , Melissa Jane Byrne
发明人： James Edward Shapland , Tuan Minh Doan , David Martin Kaye , Adam Lucas Bilney , Melissa Jane Byrne
IPC分类号： A61M31/00 , A61M29/00 , A61B19/00
CPC分类号： A61M25/10 , A61B17/22 , A61B2017/22082 , A61M1/3653 , A61M1/3659 , A61M1/3667 , A61M25/104 , A61M2025/0031 , A61M2027/004
摘要： A method for treating an occlusion in a coronary artery of a patient includes percutaneously advancing an occlusion treatment tool (such as an angioplasty balloon or stent delivery device) through the vasculature of the patient and into a coronary artery to a site of the occlusion. Following the treatment of the occlusion, a therapeutic agent is admitted into the first coronary artery. The therapeutic agent is selected to treat microvasculature obstructions at a target cardiac tissue site distal to the site of the occlusion.
摘要翻译：用于治疗患者冠状动脉闭塞的方法包括通过患者的脉管系统经皮推进闭塞治疗工具（例如血管成形术球囊或支架输送装置）并进入冠状动脉至闭塞部位。治疗闭塞后，治疗剂进入第一冠状动脉。治疗剂被选择用于治疗位于闭塞部位远端的靶心脏组织部位的微血管阻塞物。

25. 发明授权

US07938768B2 Cardiac disease treatment and device 有权
标题翻译：心脏病治疗及器械
公开(公告)号：US07938768B2
公开(公告)日：2011-05-10
申请号：US11668930
申请日：2007-01-30
申请人： James Edward Shapland , Robert G. Walsh , John David Dockter , John C. Vanden Hoek
发明人： James Edward Shapland , Robert G. Walsh , John David Dockter , John C. Vanden Hoek
IPC分类号： A61F2/00
CPC分类号： A61L31/148 , A61F2/2481 , A61F2250/0031 , A61L31/005 , A61L31/022 , A61L31/042 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/146 , C08L27/16
摘要： A cardiac constraint device comprising a jacket of biological compatible material and an adjustment member. The jacket is adapted to be secured to the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole. The adjustment mechanism is configured to alter the internal volume defined by the jacket after the jacket is secured to the heart. The invention also provides a method for treating cardiac disease.
摘要翻译：一种心脏约束装置，其包括生物相容性材料夹套和调节构件。护套适于固定在心脏上，以紧密地符合心脏的外部几何形状，并采取最大调节体积，以限制心脏周围的舒张超过舒张期的最大调节体积，并允许心脏收缩期间不受阻碍的收缩。调整机构被配置成在护套被固定到心脏之后改变由夹克限定的内部容积。本发明还提供了治疗心脏病的方法。

26. 发明申请

US20100274173A1 Regional cardiac tissue treatment 有权
公开(公告)号：US20100274173A1
公开(公告)日：2010-10-28
申请号：US12799007
申请日：2010-04-14
申请人： James Edward Shapland , Tuan Minh Doan , David Martin Kaye , Adam Lucas Bilney , Melissa Jane Byrne
发明人： James Edward Shapland , Tuan Minh Doan , David Martin Kaye , Adam Lucas Bilney , Melissa Jane Byrne
IPC分类号： A61M1/14 , A61B17/22 , A61M25/00
CPC分类号： A61M25/10 , A61B17/22 , A61B2017/22082 , A61M1/3653 , A61M1/3659 , A61M1/3667 , A61M25/104 , A61M2025/0031 , A61M2027/004
摘要： A method for treating an occlusion in a coronary artery of a patient includes percutaneously advancing an occlusion treatment tool (such as an angioplasty balloon or stent delivery device) through the vasculature of the patient and into a coronary artery to a site of the occlusion. Following the treatment of the occlusion, a therapeutic agent is admitted into the first coronary artery. The therapeutic agent is selected to treat microvasculature obstructions at a target cardiac tissue site distal to the site of the occlusion.

27. 发明申请

US20100168564A1 Remote sensing catheter system and methods 有权
标题翻译：遥感导管系统及方法
公开(公告)号：US20100168564A1
公开(公告)日：2010-07-01
申请号：US12653281
申请日：2009-12-09
申请人： James Edward Shapland , Tuan M. Doan , Christopher G. Quinn
发明人： James Edward Shapland , Tuan M. Doan , Christopher G. Quinn
IPC分类号： A61M1/00 , A61B6/00 , A61M25/00
CPC分类号： A61M1/0031 , A61M2202/049
摘要： A remote sensing catheter system including an injection catheter and a collection catheter. In one method of use, an external sensor of the system determines the timing of operation of the collection catheter. In another method of use, a sensor determines the volume of medium in the injection.
摘要翻译：一种包括注射导管和收集导管的遥感导管系统。在一种使用方法中，系统的外部传感器确定收集导管的操作时间。在另一种使用方法中，传感器确定注射器中介质的体积。

28. 发明授权

US07651462B2 Cardiac support device delivery tool with release mechanism 有权
标题翻译：带释放机构的心脏支持装置输送工具
公开(公告)号：US07651462B2
公开(公告)日：2010-01-26
申请号：US11487953
申请日：2006-07-17
申请人： Aaron J. Hjelle , James Edward Shapland , Michael Andreini , Dan Titcomb , Jeffrey Popowski , Bradley Knippel
发明人： Aaron J. Hjelle , James Edward Shapland , Michael Andreini , Dan Titcomb , Jeffrey Popowski , Bradley Knippel
IPC分类号： A61F2/00
CPC分类号： A61F2/2481 , A61F2002/2484
摘要： An apparatus for placing a cardiac support device (CSD) on a heart. The apparatus includes a body, a deployment mechanism on the body for supporting the CSD in an open position for placement on the heart, and a release mechanism coupled to the deployment mechanism for releasably mounting the CSD to the deployment mechanism. The release mechanism includes a release element for releasably engaging the CSD, and a release actuator coupled to the release element for actuating the release element to release the CSD.
摘要翻译：用于将心脏支持装置（CSD）放置在心脏上的装置。该装置包括主体，主体上用于将CSD支撑在打开位置以便放置在心脏上的展开机构，以及联接到展开机构的释放机构，用于将CSD可释放地安装到展开机构。释放机构包括用于可释放地接合CSD的释放元件和联接到释放元件的释放致动器，用于致动释放元件以释放CSD。

29. 发明申请

US20080033234A1 Cardiac support device delivery tool with release mechanism 有权
标题翻译：带释放机构的心脏支持装置输送工具
公开(公告)号：US20080033234A1
公开(公告)日：2008-02-07
申请号：US11487953
申请日：2006-07-17
申请人： Aaron J. Hjelle , James Edward Shapland , Michael Andreini , Dan Titcomb , Jeffrey Popowski , Bradley Knippel
发明人： Aaron J. Hjelle , James Edward Shapland , Michael Andreini , Dan Titcomb , Jeffrey Popowski , Bradley Knippel
IPC分类号： A61F13/00 , A61F2/00
CPC分类号： A61F2/2481 , A61F2002/2484
摘要： An apparatus for placing a cardiac support device (CSD) on a heart. The apparatus includes a body, a deployment mechanism on the body for supporting the CSD in an open position for placement on the heart, and a release mechanism coupled to the deployment mechanism for releasably mounting the CSD to the deployment mechanism. The release mechanism includes a release element for releasably engaging the CSD, and a release actuator coupled to the release element for actuating the release element to release the CSD.
摘要翻译：用于将心脏支持装置（CSD）放置在心脏上的装置。该装置包括主体，主体上用于将CSD支撑在打开位置以便放置在心脏上的展开机构，以及联接到展开机构的释放机构，用于将CSD可释放地安装到展开机构。释放机构包括用于可释放地接合CSD的释放元件和联接到释放元件的释放致动器，用于致动释放元件以释放CSD。

30. 发明授权

US06370429B1 Defibrillating cardiac constraint 有权
标题翻译：去纤颤心脏约束
公开(公告)号：US06370429B1
公开(公告)日：2002-04-09
申请号：US09628706
申请日：2000-07-31
申请人： Clifton A. Alferness , James Edward Shapland
发明人： Clifton A. Alferness , James Edward Shapland
IPC分类号： A61N139
CPC分类号： A61N1/0563 , A61F2/2481 , A61F2002/0068
摘要： A device for treating cardiac disease of a heart includes a jacket of flexible material defining a volume between an open upper end and a lower end. The jacket is dimensioned for an apex of the heart to be inserted into the volume through the open upper end and for the jacket to be slipped over the heart. The jacket is adapted to be secured to the heart with the jacket having portions disposed on opposite sides of the heart. The jacket is adjustable to snugly conform to an external geometry of the heart and to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole. A first and a second grid of electrodes are carried on the jacket. The grids are disposed to be in overlying relation to individual ones of the opposite sides of the heart when the jacket is secured to the heart. The first and second grids are connectable to a source of a defibrillating waveform
摘要翻译：用于治疗心脏心脏病的装置包括限定在开放的上端和下端之间的体积的柔性材料的护套。外套的尺寸适用于通过开放的上端插入体积的心脏的顶点，并且夹套被滑过心脏。护套适于固定在心脏上，护套具有设置在心脏的相对侧上的部分。护套是可调节的，以贴合地符合心脏的外部几何形状，并且在舒张期期间约束心脏的周向扩张，并且允许心脏在收缩期间基本上不受阻碍地收缩心脏。电极的第一和第二格栅承载在护套上。当护套被固定在心脏上时，网格被布置成与心脏的相对侧中的个体相对重叠。第一和第二栅极可连接到除颤波形的源

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