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21. 发明授权

US07176547B2 Semiconductor device 有权
标题翻译：半导体器件
公开(公告)号：US07176547B2
公开(公告)日：2007-02-13
申请号：US11438068
申请日：2006-05-22
申请人： Akihiro Hasegawa
发明人： Akihiro Hasegawa
IPC分类号： H01L31/075 , H01L31/105 , H01L31/117
CPC分类号： H01L31/02024 , H01L31/105
摘要： A four-division photodetector where a formation process of an element isolation structure is simplified is provided. On a P-sub layer that is a common anode of PIN photodiodes (PIN-PD) for every partition, a high resistivity epitaxial layer that is an i layer of the PIN-PD is grown. At a boundary of the partitions, ion implantation is applied from a substrate surface to form an isolation region that is a P+ region. When a cathode region formed for every partition and the P-sub layer are reverse-biased to operate the PIN-PD, the isolation region is set at a ground potential together with the P-sub layer to operate as an anode. As a result, in the epitaxial layer at a position sandwiched between the isolation region and the P-sub layer, a potential barrier to electrons is formed. As a result, electrons generated owing to light absorption in the respective partitions can be inhibited from moving to adjacent partitions and element isolation can thus be realized.
摘要翻译：提供了一种简化元件隔离结构的形成过程的四分光电检测器。在作为每个分区的PIN光电二极管（PIN-PD）的公共阳极的P子层上，生长作为PIN-PD的i层的高电阻率外延层。在隔板的边界处，从衬底表面施加离子注入以形成作为P + +区域的隔离区域。当为每个分区形成的阴极区域和P子层被反向偏置以操作PIN-PD时，隔离区域与P子层一起设置为接地电位以用作阳极。结果，在夹在隔离区域和P-sub层之间的位置的外延层中形成电子势垒。结果，可以抑制由于各分区中的光吸收而产生的电子移动到相邻的分区，从而可以实现元件隔离。

22. 发明申请

US20060180920A1 Semiconductor device and manufacturing method thereof 有权
标题翻译：半导体装置及其制造方法
公开(公告)号：US20060180920A1
公开(公告)日：2006-08-17
申请号：US11393655
申请日：2006-03-31
申请人： Akihiro Hasegawa
发明人： Akihiro Hasegawa
IPC分类号： H01L23/12
CPC分类号： H01L21/76834 , H01L21/76843 , H01L21/76852 , H01L21/76885 , H01L23/5226 , H01L23/5283 , H01L23/53238 , H01L23/53295 , H01L2924/0002 , H01L2924/00
摘要： After an interlayer insulation film (1) and a CMP stopper film are formed, wiring trenches are formed. Next, after a barrier metal film (4) and a Cu film (5) are buried in the wiring trenches, the Cu film (5) and the barrier metal film (4) are planarized by CMP or the like until the CMP stopper film is exposed, whereby lower wirings (17) are formed. Next, the CMP stopper film is removed by dry etching, so that surfaces of the lower wirings (17) relatively protrude from their surrounding area. Subsequently, an etching stopper film (6) is formed on the entire surface. Thereafter, via plugs (18) are formed, and upper wirings (19) are further formed in the same manner as the lower wirings (17).
摘要翻译：在形成层间绝缘膜（1）和CMP阻挡膜之后，形成布线沟槽。接下来，在阻挡金属膜（4）和Cu膜（5）埋设在布线沟槽中之后，通过CMP等将Cu膜（5）和阻挡金属膜（4）平坦化，直到CMP阻挡膜被暴露，从而形成下布线（17）。接下来，通过干蚀刻去除CMP阻挡膜，使得下布线（17）的表面从其周围区域相对突出。随后，在整个表面上形成蚀刻停止膜（6）。此后，形成通过插头（18），并且以与下布线（17）相同的方式进一步形成上布线（19）。

23. 发明申请

US20050274645A1 Substrate storage container 有权
标题翻译：基材储存容器
公开(公告)号：US20050274645A1
公开(公告)日：2005-12-15
申请号：US11148147
申请日：2005-06-08
申请人： Akihiro Hasegawa , Hiroshi Mimura
发明人： Akihiro Hasegawa , Hiroshi Mimura
IPC分类号： B65D85/86 , H01L21/00 , H01L21/673 , B65D85/30
CPC分类号： H01L21/67369 , H01L21/67376 , H01L21/67383
摘要： A substrate storage container comprises: a container casing having an aperture through which a plurality of substrates are placed in or taken out; a cover adapted to fit into the aperture of the container casing; a sealing gasket capable of elastic deformation provided between the container casing and the cover, and a retainer, mounted on the cover, capable of retaining the periphery of the substrates. The retainer has: a supporting body mounted on the inside face of the cover; a plurality of elastic pieces provided in elastically deformable fashion on the supporting body; and a block provided on each of the elastic pieces, the block retaining the periphery of one of the substrates. A relation 10.8×w
摘要翻译：衬底存储容器包括：具有孔的容器壳体，多个衬底通过所述孔放置或取出; 适于装配到容器壳体的孔中的盖; 能够在容器壳体和盖之间设置弹性变形的密封垫，以及安装在盖上的能够保持基板周边的保持器。保持器具有：安装在盖的内表面上的支撑体; 在所述支撑体上以可弹性变形的方式设置的多个弹性片; 以及设置在每个弹性片上的块，该块保持一个基板的周边。当每个弹性片的基板保持力为y [单位：N]时，满足10.8×w

24. 发明申请

US20120049303A1 SEMICONDUCTOR DEVICE 有权
标题翻译：半导体器件
公开(公告)号：US20120049303A1
公开(公告)日：2012-03-01
申请号：US13215584
申请日：2011-08-23
申请人： Takashi Ogawa , Hironori Terazawa , Akihiro Hasegawa , Takashi Naruse , Yuuhei Mouri
发明人： Takashi Ogawa , Hironori Terazawa , Akihiro Hasegawa , Takashi Naruse , Yuuhei Mouri
IPC分类号： H01L43/08
CPC分类号： G01D3/036
摘要： A semiconductor device includes a Hall element, which is switched between a first and second mode. In the first mode, connection A between a first and second resistor and connection C between a third and fourth resistor are set to Vcc or GND. Connection D between the first and fourth resistor and connection B between the second and third resistor are set as output terminals. In the second mode, D and B are set to Vcc or GND and A and C are set as output terminals. When a first line placed along the second resistor and connected to A is set at Vcc in the first mode, a second line placed along the fourth resistor and connected to D is set at Vcc in the second mode. When the first line is set at GND in first mode, the second line is set at GND in the second mode.
摘要翻译：半导体器件包括在第一和第二模式之间切换的霍尔元件。在第一模式中，第一和第二电阻之间的连接A与第三和第四电阻之间的连接C被设置为Vcc或GND。第一和第四电阻之间的连接D和第二和第三电阻之间的连接B被设置为输出端。在第二模式中，D和B设置为Vcc或GND，A和C设置为输出端。当在第一模式中沿着第二电阻器放置并连接到A的第一线路被设置为Vcc时，在第二模式中沿着第四电阻器放置并连接到D的第二线路被设置为Vcc。当在第一模式下将第一行设置为GND时，第二行在第二模式下设置为GND。

25. 发明授权

US08022176B2 FAS peptide mimetics and uses thereof 有权
标题翻译： FAS肽模拟物及其用途
公开(公告)号：US08022176B2
公开(公告)日：2011-09-20
申请号：US11869556
申请日：2007-10-09
申请人： Mark I. Greene , Ramachandran Murali , Akihiro Hasegawa
发明人： Mark I. Greene , Ramachandran Murali , Akihiro Hasegawa
IPC分类号： A61K38/12
CPC分类号： C07K14/70578 , A61K38/00
摘要： Exocyclic peptide mimetics that disable Fas were developed. A three dimensional model of the Fas receptor-ligand complex was constructed and structurally predicted regions of the receptor that were relevant to binding ligand were used to create constrained peptide mimetics. Exocyclic anti-Fas peptide mimetics were identified that block Fas receptor-ligand interactions, and modulate Fas biological activity both in vitro and in vivo. The mimetics are useful, e.g., for treating Fas-related pathologies.
摘要翻译：开发了禁用Fas的外来肽模拟物。构建了Fas受体 - 配体复合物的三维模型，并且结构上预测与结合配体相关的受体区域用于产生约束肽模拟物。鉴定了外环抗Fas肽模拟物阻断Fas受体 - 配体相互作用，并在体外和体内调节Fas生物活性。模拟物可用于例如治疗Fas相关病理学。

26. 发明申请

US20110033388A1 IMAGEABLE RODENT MODEL OF ASTHMA 审中-公开
标题翻译： ASTHMA的成像模型
公开(公告)号：US20110033388A1
公开(公告)日：2011-02-10
申请号：US12681348
申请日：2008-10-01
申请人： Akihiro Hasegawa , Toshinori Nakayama , Meng Yang
发明人： Akihiro Hasegawa , Toshinori Nakayama , Meng Yang
IPC分类号： A61K49/00 , A01K67/00
CPC分类号： A01K67/0271 , A01K2227/105 , A01K2267/0387 , A01K2267/0393
摘要： An imageable rodent model for asthma is described. The invention provides a rodent model for asthma wherein a rodent is provided with fluorescently labeled lymphocytes sensitized to an allergen which can be monitored after inducing an asthmatic response by the allergen. Methods to monitor trafficking of the fluorescently labeled cells in the rodent model for asthma are provided. Methods to determine the effectiveness of candidate drugs that regulate asthmatic responses using the rodent asthma model are also provided.
摘要翻译：描述了用于哮喘的可成像的啮齿动物模型。本发明提供了一种用于哮喘的啮齿动物模型，其中给啮齿动物提供对变应原敏感的荧光标记的淋巴细胞，其可以在诱导过敏原的哮喘反应之后被监测。提供了在哮喘啮齿动物模型中监测荧光标记细胞运输的方法。还提供了确定使用啮齿动物哮喘模型调节哮喘反应的候选药物有效性的方法。

27. 发明申请

US20090026109A1 STORAGE CONTAINER 有权
标题翻译：储物容器
公开(公告)号：US20090026109A1
公开(公告)日：2009-01-29
申请号：US11817574
申请日：2006-03-30
申请人： Akihiro Hasegawa , Hiroshi Mimura
发明人： Akihiro Hasegawa , Hiroshi Mimura
IPC分类号： B65D85/00
CPC分类号： H01L21/67373 , Y10S292/11 , Y10T70/5261 , Y10T70/5279 , Y10T70/5327 , Y10T292/0848 , Y10T292/0854 , Y10T292/444
摘要： To provide a storage container which can inhibit and prevent generation of dust due to the motions of an advancing and retracting element, whose door element can be formed with a reduced space and thickness and which can prevent contamination of the articles accommodated therein, the storage container includes a container body 1 for storing precision substrates, a door element 10 that opens and closes the front of container body 1 and a locking mechanism 20 for locking and unlocking door element 10 that covers container body 1. Locking mechanism 20 is constructed of a rotary plate 21 that is supported by door element 10, a first advancing and retracting plate 26 that, in accordance with the rotation of rotary plate 21, advances toward the peripheral wall of door element 10 when door element 10 is locked and retracts to the reference position inside door element 10 when door element 10 is unlocked; a second advancing and retracting plate 32 which is supported by the front end part of first advancing and retracting plate 26, and projects out from the peripheral wall of door element 10 and fits into an engaging recess 3 of container body 1 when door element 10 is locked and returns from engaging recess 3 of container body 1 toward the door element when door element 10 is unlocked; a guide rib 37 which makes the second advancing and retracting plate 32 incline in the thickness direction of the door element 10 as the plate is being projected.
摘要翻译：为了提供一种存储容器，其能够抑制和防止由于前进和后退元件的运动引起的灰尘的产生，其门元件可以形成为具有减小的空间和厚度并且可以防止其中容纳的物品的污染，包括用于存储精密基板的容器主体1，打开和关闭容器主体1的前部的门元件10和用于锁定和解锁盖体10的门元件10的锁定机构20.锁定机构20由旋转由门元件10支撑的板21，当门元件10被锁定并且缩回到参考位置时，根据旋转板21的旋转朝向门元件10的周壁前进的第一前进和后退板26 门元件10被解锁时的内门元件10; 第二前进退回板32，其由第一前进退回板26的前端部支撑，并且当门元件10为门元件10时从门元件10的周壁突出并配合到容器主体1的接合凹部3中当门元件10解锁时，锁定并从容器主体1的接合凹部3返回门元件; 引导肋37，其使得当板被投影时，第二前进和后退板32在门元件10的厚度方向上倾斜。

28. 发明申请

US20080153742A1 FAS PEPTIDE MIMETICS AND USES THEREOF 有权
标题翻译： FAS PEPTIDE MIME及其用途
公开(公告)号：US20080153742A1
公开(公告)日：2008-06-26
申请号：US11869556
申请日：2007-10-09
申请人： Mark I. Greene , Ramachandran Murali , Akihiro Hasegawa
发明人： Mark I. Greene , Ramachandran Murali , Akihiro Hasegawa
IPC分类号： A61K38/12 , C07K2/00 , C07K7/06 , A61P43/00 , A61K38/08
CPC分类号： C07K14/70578 , A61K38/00
摘要： Exocyclic peptide mimetics that disable Fas were developed. A three dimensional model of the Fas receptor-ligand complex was constructed and structurally predicted regions of the receptor that were relevant to binding ligand were used to create constrained peptide mimetics. Exocyclic anti-Fas peptide mimetics were identified that block Fas receptor-ligand interactions, and modulate Fas biological activity both in vitro and in vivo. The mimetics are useful, e.g., for treating Fas-related pathologies.
摘要翻译：开发了禁用Fas的外来肽模拟物。构建了Fas受体 - 配体复合物的三维模型，并且结构上预测与结合配体相关的受体区域用于产生约束肽模拟物。鉴定了外环抗Fas肽模拟物阻断Fas受体 - 配体相互作用，并在体外和体内调节Fas生物活性。模拟物可用于例如治疗Fas相关病理学。

29. 发明授权

US07344031B2 Substrate storage container 有权
标题翻译：基材储存容器
公开(公告)号：US07344031B2
公开(公告)日：2008-03-18
申请号：US11148147
申请日：2005-06-08
申请人： Akihiro Hasegawa , Hiroshi Mimura
发明人： Akihiro Hasegawa , Hiroshi Mimura
IPC分类号： B65D85/48
CPC分类号： H01L21/67369 , H01L21/67376 , H01L21/67383
摘要： A substrate storage container comprises: a container casing having an aperture through which a plurality of substrates are placed in or taken out; a cover adapted to fit into the aperture of the container casing; a sealing gasket capable of elastic deformation provided between the container casing and the cover; and a retainer, mounted on the cover, capable of retaining the periphery of the substrates. The retainer has: a supporting body mounted on the inside face of the cover; a plurality of elastic pieces provided in elastically deformable fashion on the supporting body; and a block provided on each of the elastic pieces, the block retaining the periphery of one of the substrates. A relation 10.8×w
摘要翻译：衬底存储容器包括：具有孔的容器壳体，多个衬底通过所述孔放置或取出; 适于装配到容器壳体的孔中的盖; 能够在容器壳体和盖之间设置弹性变形的密封垫片; 以及安装在盖上的保持器，其能够保持基板的周边。保持器具有：安装在盖的内表面上的支撑体; 在所述支撑体上以可弹性变形的方式设置的多个弹性片; 以及设置在每个弹性片上的块，该块保持一个基板的周边。当每个弹性片的衬底保持力为y [单位：N]时，满足10.8×w

30. 发明申请

US20060283774A1 Substrate storage container and method for manufacturing the same 审中-公开
标题翻译：基材储存容器及其制造方法
公开(公告)号：US20060283774A1
公开(公告)日：2006-12-21
申请号：US11436040
申请日：2006-05-17
申请人： Akihiro Hasegawa , Hiroshi Mimura
发明人： Akihiro Hasegawa , Hiroshi Mimura
IPC分类号： B65D85/00
CPC分类号： H01L21/67369 , H01L21/67383
摘要： A substrate storage container includes a container main body, first supporting parts and second supporting parts. The container main body includes a back wall and a pair of side walls in order to store a substrate between the side walls. The first supporting parts are opposingly disposed on each side wall in order to support a peripheral edge part of the substrate. The second supporting parts are opposingly disposed on each side wall in order to support the peripheral edge part of the substrate and positioned between the back wall and the first supporting parts. The first supporting parts and the second supporting parts are covered with a resin layer having a lower frictional property than that of the container main body.
摘要翻译：基板储存容器包括容器主体，第一支撑部和第二支撑部。容器主体包括后壁和一对侧壁，以便在侧壁之间存储基底。第一支撑部件相对设置在每个侧壁上以便支撑基板的周边部分。第二支撑部件相对地设置在每个侧壁上，以便支撑基板的周缘部分并且位于后壁和第一支撑部分之间。第一支撑部分和第二支撑部分被具有比容器主体的摩擦特性低的树脂层覆盖。

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