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21. 发明申请

US20130017181A1 LIPID-METABOLISM-AMELIORATING AGENT 审中-公开
标题翻译：脂肪代谢改性剂
公开(公告)号：US20130017181A1
公开(公告)日：2013-01-17
申请号：US13418032
申请日：2012-03-12
申请人： Hiromi Suzuki , Shigeru Fujiwara
发明人： Hiromi Suzuki , Shigeru Fujiwara
IPC分类号： A61K35/74 , A61P3/00 , A61P3/06
CPC分类号： A61K35/74 , A61K35/744
摘要： Methods for lowering serum triglycerides use pharmaceutical agents and food products that have no side effects, are easy to ingest continuously, and have a serum triglyceride-lowering effect are provided. The pharmaceutical agents and food products are lipid metabolism-ameliorating agents and serum triglyceride-lowering agents, which include as an active ingredient a culture of a bacterium belonging to the genus Bacillus. The bacterium belongs to the genus Bacillus is preferably Bacillus subtilis, and more preferably Bacillus subtilis C-3102 (FERM BP-1096). The lipid metabolism-ameliorating agent and the serum triglyceride-lowering agent are useful for treating and preventing diseases such as arteriosclerosis.
摘要翻译：降低血清甘油三酸酯的方法使用没有副作用的药剂和食品，容易连续摄取，并具有血清甘油三酯降低效果。药剂和食品是脂质代谢改善剂和血清甘油三酯降低剂，其作为活性成分包括属于芽孢杆菌属的细菌的培养物。细菌属于芽孢杆菌属，优选枯草芽孢杆菌，更优选枯草芽孢杆菌C-3102（FERM BP-1096）。脂质代谢改善剂和血清甘油三酯降低剂可用于治疗和预防动脉硬化等疾病。

22. 发明申请

US20120321335A1 FIXING DEVICE AND IMAGE FORMING APPARATUS 有权
标题翻译：固定装置和图像形成装置
公开(公告)号：US20120321335A1
公开(公告)日：2012-12-20
申请号：US13493059
申请日：2012-06-11
申请人： Shigeru Fujiwara
发明人： Shigeru Fujiwara
IPC分类号： G03G15/20
CPC分类号： G03G15/2078 , G03G15/2039 , G03G2215/2009
摘要： A fixing device of an embodiment is configured to fix an unfixed toner image formed of a decolorable toner on a sheet of paper. The fixing device includes: a fixing unit including a fixing member heated by a first heat source and a pressure member heated by a second heat source; a first temperature sensor and a second temperature sensor; and a temperature controller configured to control the first heat source and the second heat source separately for temperature control based on detected temperature information acquired by the temperature sensors, wherein the temperature controller controls the surface temperatures of the fixing member and the pressure member to set equal or above the temperature at which fixing is started fixing starting temperature and to set below the temperature at which decolorization is started, and such that the surface temperatures of the fixing member and the pressure member become substantially the same temperature.
摘要翻译：实施例的定影装置被配置为将由不可剥色调剂形成的未定影调色剂图像固定在一张纸上。定影装置包括：固定单元，包括由第一热源加热的固定构件和由第二热源加热的压力构件; 第一温度传感器和第二温度传感器; 以及温度控制器，其被配置为基于由所述温度传感器获取的检测到的温度信息来分别控制所述第一热源和所述第二热源以进行温度控制，其中所述温度控制器控制所述固定构件和所述压力构件的表面温度以相等或高于开始固定开始温度的温度并且设定为低于开始脱色的温度，并且使得固定构件和压力构件的表面温度变得基本相同的温度。

23. 发明授权

US08226937B2 Agents for promoting IgA production 失效
标题翻译：促进IgA生产的药剂
公开(公告)号：US08226937B2
公开(公告)日：2012-07-24
申请号：US13208597
申请日：2011-08-12
申请人： Satoshi Hachimura , Hiroki Kanzato , Shigeru Fujiwara
发明人： Satoshi Hachimura , Hiroki Kanzato , Shigeru Fujiwara
IPC分类号： A61K39/02
CPC分类号： C12R1/225 , A61K35/747 , C12N1/20
摘要： The present invention provides Lactobacillus bacteria which enhance the functional of Peyer's patch and promote IgA production and which have a characteristics of localizing on human intestine as well as an agent for promoting IgA production. The present invention is directed to an agent for promoting IgA production containing Lactobacillus amylovorus cells, especially Lactobacillus amylovorus CP1750 (FERM BP-10532) as an active ingredient.
摘要翻译：本发明提供了增强派尔氏贴剂功能并促进IgA生产并且具有定位在人肠上的特征以及用于促进IgA生产的药剂的乳杆菌属细菌。本发明涉及用于促进含有乳酸干酪乳杆菌细胞，特别是乳酸乳杆菌CP1750（FERM BP-10532）作为活性成分的IgA生产的药剂。

24. 发明申请

US20110250189A1 T CELL APOPTOSIS INDUCER 有权
标题翻译：细胞凋亡诱导因子
公开(公告)号：US20110250189A1
公开(公告)日：2011-10-13
申请号：US13167483
申请日：2011-06-23
申请人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
发明人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
IPC分类号： A61K35/74 , C12N1/20 , A61P43/00
CPC分类号： A23L1/3014 , A23L33/135 , A23Y2220/05 , A23Y2300/55 , A61K35/745 , A61K35/747 , C12N1/20 , C12R1/225 , C12R1/23
摘要： An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.
摘要翻译：公开了一种T细胞凋亡诱导剂和用于诱导T细胞凋亡的保健食品，其包含属于乳杆菌属或双歧杆菌属的乳酸菌的活性成分。属于乳杆菌属或双歧杆菌属的特别优选的乳酸菌是嗜酸乳杆菌L-92（FERM BP-4981），淀粉乳杆菌CP1750（FERM BP-10532），连锁双歧杆菌CP2829（FERM BP-10533）和长双歧杆菌CP760 （FERM BP-10531）。本发明的T细胞凋亡诱导剂可用于预防和治疗诸如器官特异性自身免疫性疾病或I型变态反应的疾病。

25. 发明授权

US07983588B2 Image forming apparatus with cleaning device that does not cause excessive cutting and cleaning method 有权
标题翻译：具有清洁装置的图像形成装置，其不会引起过度的切割和清洁方法
公开(公告)号：US07983588B2
公开(公告)日：2011-07-19
申请号：US12822506
申请日：2010-06-24
申请人： Shigeru Fujiwara
发明人： Shigeru Fujiwara
IPC分类号： G03G15/16
CPC分类号： G03G21/0029
摘要： In an image forming apparatus including a cleaning device having a cleaning blade arranged so as to make contact with and separate from a cleaned surface, an occurrence of excessive cutting when the cleaning blade makes contact with the cleaned surface is prevented. The image forming apparatus includes the cleaning blade for making contact with and separating from the cleaned surface and scraping off toner adhered onto the cleaned surface and a regulation member for regulating a movement of the cleaning blade in the direction of contact with the cleaned surface up to a position where a pressing force to the cleaned surface by the cleaning blade does not exceed a predetermined pressing force.
摘要翻译：在包括具有布置成与清洁表面接触并与其分离的清洁刮板的清洁装置的图像形成装置中，防止了当清洁刮板与清洁表面接触时出现过度切割。图像形成装置包括用于与清洁表面接触和分离并清除附着在清洁表面上的调色剂的清洁刮板和用于调节清洁刮板沿与清洁表面接触的方向的移动的调节构件，直到通过清洁刮板对清洁表面的按压力不超过预定的按压力的位置。

26. 发明申请

US20100248369A1 RENAL-FUNCTION-AMELIORATING AGENT 审中-公开
标题翻译：肾功能调节剂
公开(公告)号：US20100248369A1
公开(公告)日：2010-09-30
申请号：US12438275
申请日：2007-08-14
申请人： Hiromi Suzuki , Shigeru Fujiwara
发明人： Hiromi Suzuki , Shigeru Fujiwara
IPC分类号： C12N5/04 , C12N1/20
CPC分类号： A61K35/74 , A61K35/744
摘要： A renal function-ameliorating agent and a serum creatinine-lowering agent, each comprising as an active ingredient a culture of a bacterium belonging to the genus Bacillus, are disclosed. The bacterium belonging to the genus Bacillus is preferably Bacillus subtilis, and more preferably Bacillus subtilis C-3102 (FERM BP-1096). The renal function-ameliorating agent and the serum creatinine-lowering agent are useful for treating and preventing diseases such as arteriosclerosis.
摘要翻译：公开了一种肾功能改善剂和血清肌酐降低剂，其各自包含属于芽孢杆菌属的细菌的培养物作为活性成分。属于芽孢杆菌属的细菌优选是枯草芽孢杆菌，更优选枯草芽孢杆菌C-3102（FERM BP-1096）。肾功能改善剂和血肌酐降低剂可用于治疗和预防动脉硬化等疾病。

27. 发明授权

US07236276B2 Image forming apparatus and image forming method 有权
标题翻译：图像形成装置及图像形成方法
公开(公告)号：US07236276B2
公开(公告)日：2007-06-26
申请号：US10392302
申请日：2003-03-20
申请人： Rintaro Nakane , Shigeru Fujiwara , Hideaki Fukaya
发明人： Rintaro Nakane , Shigeru Fujiwara , Hideaki Fukaya
IPC分类号： G03F3/08
CPC分类号： H04N1/40006 , H04N1/4076
摘要： A gradation pattern is printed, the gradation pattern is corrected with a gamma correction table TO based on a result in which the printed gradation pattern is read, the corrected gradation pattern is printed on a photosensitive drum or the like, and a measured density of the printed gradation pattern in S4 is stored as a reference value of density DR. Thereafter, without user's operation, at a set automatic timing, the read gradation pattern P is corrected with the gamma correction table TO and printed on the photosensitive drum or the like, density deviation ΔD between a measured density D of the printed gradation pattern in S6 and the reference value of density DR is determined, and the latest gamma correction table T is generated and updated on the basis of the density deviation ΔD. Consequently, high-quality image formation can be automatically performed.
摘要翻译：打印渐变图案，基于读取打印的渐变图案的结果，将校正的灰度图案印刷在感光鼓上或者将感光鼓打印到灰度校正表T O0 并且将S 4中的印刷灰度图案的测量密度存储为密度D R R的参考值。此后，在没有用户操作的情况下，在设定的自动定时时，读取的灰度图案P用伽马校正表T O O 0进行校正并打印在感光鼓等上，测量密度之间的密度偏差ΔD 确定S 6中的印刷灰度图案的D和密度D 的参考值，并且基于密度偏差DeltaD生成和更新最新的伽马校正表T. 因此，可以自动执行高质量的图像形成。

28. 发明申请

US20070003316A1 Image forming apparatus with cleaning device and cleaning method 有权
标题翻译：具有清洁装置和清洁方法的图像形成装置
公开(公告)号：US20070003316A1
公开(公告)日：2007-01-04
申请号：US11447346
申请日：2006-06-06
申请人： Shigeru Fujiwara
发明人： Shigeru Fujiwara
IPC分类号： G03G15/16
CPC分类号： G03G21/0029
摘要： In an image forming apparatus including a cleaning device having a cleaning blade arranged so as to make contact with and separate from a cleaned surface, an occurrence of excessive cutting when the cleaning blade makes contact with the cleaned surface is prevented. The image forming apparatus includes the cleaning blade for making contact with and separating from the cleaned surface and scraping off toner adhered onto the cleaned surface and a regulation unit for regulating a movement of the cleaning blade in the direction of contact with the cleaned surface up to a position where a pressing force to the cleaned surface by the cleaning blade does not exceed a predetermined pressing force.
摘要翻译：在包括具有布置成与清洁表面接触并与其分离的清洁刮板的清洁装置的图像形成装置中，防止了当清洁刮板与清洁表面接触时出现过度切割。图像形成装置包括用于与清洁表面接触并与其分离并清除附着在清洁表面上的调色剂的清洁刮板和用于调节清洁刮板沿与清洁表面接触的方向的运动的调节单元，直到通过清洁刮板对清洁表面的按压力不超过预定的按压力的位置。

29. 发明授权

US5486907A Brush charging device for an image forming apparatus and a method for manufacturing the same 失效
标题翻译：用于图像形成装置的刷子充电装置及其制造方法
公开(公告)号：US5486907A
公开(公告)日：1996-01-23
申请号：US208708
申请日：1994-03-11
申请人： Takeshi Watanabe , Minoru Yoshida , Shigeru Fujiwara , Masashi Takahashi
发明人： Takeshi Watanabe , Minoru Yoshida , Shigeru Fujiwara , Masashi Takahashi
IPC分类号： A46B15/00 , G03G15/02
CPC分类号： G03G15/0216
摘要： A brush charging device for an image forming apparatus, which charges a surface of an image carrier rotating in a predetermined direction, has a linear mount member, a base cloth mounted on the mount member and a brush member having fibers mounted on the base cloth at an angle .theta..sub.1. The angle .theta..sub.1 satisfies the following formula: cos.theta..sub.1 >c/(a+b) wherein a represents the radius of the image carrier, b represents the length of the brush fibers and c represents the distance between a point of intersection where a perpendicular line extending from the center of the image carrier to the base cloth intersects the base cloth and an edge portion of the base cloth located upstream going in the direction of the image carrier, and where the brush fibers contact the surface of the image carrier.
摘要翻译：一种用于图像形成装置的电刷充电装置，其对沿预定方向旋转的图像载体的表面进行充电，具有直线安装构件，安装在安装构件上的基布和安装在基布上的纤维的刷构件角度θ1。角度θ1满足以下公式：cosθ1> c /（a + b）其中a表示图像载体的半径，b表示刷状纤维的长度，c表示a 从图像载体的中心延伸到基布的垂直线与基布相交的位置点和位于沿图像载体的方向上游的基布的边缘部分的交点处，并且刷纤维接触表面的图像载体。

30. 发明授权

US5461312A Remote field eddy current sensor for detecting flaws in metal material 失效
标题翻译：用于检测金属材料缺陷的远场涡流传感器
公开(公告)号：US5461312A
公开(公告)日：1995-10-24
申请号：US222863
申请日：1994-04-05
申请人： Yasuharu Hosohara , Kiwamu Suzuki , Shigeru Fujiwara , Toshihide Kawabe
发明人： Yasuharu Hosohara , Kiwamu Suzuki , Shigeru Fujiwara , Toshihide Kawabe
IPC分类号： G01N27/90
CPC分类号： G01N27/902 , G01N27/9046
摘要： The present invention relates to a flaw detector for metal material for maintaining and managing pipelines using a remote field eddy current sensor. An AC signal having constant level and shifted by predetermined phase angle is added to signals received in receiving coils of the remote field eddy current sensor to obtain accurate phase detection in a normal, nonflawed portion of the pipeline to be tested (e.g. uniform thickness, no holes, etc.). By preventing generation of abnormal flaw data, precise diagnosis of the pipeline can be performed. An AGC circuit may be used to maintain at a constant level of received signal. Two sets of spaced apart receiving coils are spaced from an exciting coil a distance greater than a predetermined distance (about two times the pipeline diameter). The set of receiving coils closest to the exciting coil has a greater number of coil turns than the other set. This coil configuration generates sensed coil differential signals having sufficient signal amplitude to permit stabilized and accurate phase detection and comparison for nonflawed and gradually flawed regions in the pipe.
摘要翻译：本发明涉及一种用于使用远场涡流传感器维护和管理管线的金属材料探伤仪。将具有恒定电平并且移位了预定相位角的AC信号添加到在远场涡流传感器的接收线圈中接收的信号，以在要测试的管线的正常非缺陷部分中获得准确的相位检测（例如，均匀厚度，否孔等）。通过防止产生异常缺陷数据，可以进行流水线的精确诊断。可以使用AGC电路来维持在接收信号的恒定电平。两组间隔开的接收线圈与激励线圈间隔大于预定距离（约为管道直径的两倍）。最靠近励磁线圈的接收线圈组比其他组具有更多的线圈匝数。该线圈配置产生具有足够信号幅度的感测线圈差分信号，以允许对管道中非缺陷和逐渐有缺陷的区域进行稳定和精确的相位检测和比较。

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