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21. 发明申请

US20110152806A1 ABSORBENT ARTICLE HAVING A SIGNAL COMPOSITE 有权
标题翻译：具有信号复合材料的吸收性物品
公开(公告)号：US20110152806A1
公开(公告)日：2011-06-23
申请号：US12646763
申请日：2009-12-23
申请人： Peiguang Zhou , Andrew Mark Long , Dave Allen Soerens , Kaiyuan Yang , Davis-Dang Hoang Nhan
发明人： Peiguang Zhou , Andrew Mark Long , Dave Allen Soerens , Kaiyuan Yang , Davis-Dang Hoang Nhan
IPC分类号： A61F13/42 , A61F13/15
CPC分类号： A61F13/42
摘要： An absorbent article comprises a signal composite comprising a carrier substrate layer, a first stimulation layer, a second stimulation layer, a first thermoplastic adhesive layer and a second thermoplastic adhesive layer. The carrier substrate layer is disposed as a bottom layer of the signal composite. The first stimulation layer comprises a first stimulation material and is disposed above and adjacent to the carrier substrate layer. The second stimulation layer comprises a second stimulation material and is disposed above and adjacent to the first stimulation layer to provide the body-facing surface of the signal composite. The first thermoplastic adhesive layer is liquid permeable or water-soluble and is disposed between and adjacent to the carrier substrate layer and the first stimulation layer. The second thermoplastic adhesive layer is liquid permeable or water-soluble and is disposed between the first stimulation layer and the second stimulation layer.
摘要翻译：吸收制品包括信号复合材料，其包括载体基底层，第一刺激层，第二刺激层，第一热塑性粘合剂层和第二热塑性粘合剂层。载体基底层被设置为信号复合材料的底层。第一刺激层包括第一刺激材料，并且设置在载体基底层的上方和附近。第二刺激层包括第二刺激材料并且设置在第一刺激层的上方并与其相邻以提供信号复合材料的面向身体的表面。第一热塑性粘合剂层是液体可渗透的或水溶性的，并且设置在载体基底层和第一刺激层之间且与载体基底层和第一刺激层相邻。第二热塑性粘合剂层是液体可渗透的或水溶性的，并且设置在第一刺激层和第二刺激层之间。

22. 发明授权

US07943089B2 Laminated assay devices 有权
标题翻译：层压测定装置
公开(公告)号：US07943089B2
公开(公告)日：2011-05-17
申请号：US10741434
申请日：2003-12-19
申请人： Kaiyuan Yang , Xuedong Song , Rosann Kaylor
发明人： Kaiyuan Yang , Xuedong Song , Rosann Kaylor
IPC分类号： G01N27/00
CPC分类号： G01N33/5438
摘要： An electrochemical-based assay device capable of detecting the presence or quantity of an analyte of interest that is provided. The device contains two or more substrates, one containing a detection working electrode and another containing an auxiliary electrode, such as a counter/reference electrode(s). The substrates are positioned in a face-to-face relationship so that the electrodes are adjacent to each other during performance of the assay. Besides the electrodes, any of a variety of other components may also be employed in the assay device.
摘要翻译：能够检测所提供的感兴趣分析物的存在或数量的基于电化学的测定装置。该装置包含两个或更多个基板，一个包含检测工作电极，另一个基板包含辅助电极，例如计数器/参考电极。基板以面对面的关系定位，使得在测定过程中电极彼此相邻。除了电极之外，还可以在测定装置中使用各种其它组分中的任何一种。

23. 发明授权

US07858568B2 Single phase color change agents 有权
标题翻译：单相变色剂
公开(公告)号：US07858568B2
公开(公告)日：2010-12-28
申请号：US12692003
申请日：2010-01-22
申请人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
发明人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
IPC分类号： A61K7/00
CPC分类号： C11D3/221 , C11D3/0042 , C11D3/40
摘要： There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.
摘要翻译：提供了颜色变化组合物，其在单一相中保持稳定，并且包含在一段时间之后产生可观察到的颜色变化的指示剂，以显示已经进行足够的清洁或指示清洁的彻底性。指示颜色变化的这种用途对于例如在肥皂中教孩子们洗手足够长时间是有用的。这种组合物可以添加到许多不同的基础材料中以指示使用时间或作为向活动引入享受的方式。

24. 发明授权

US07838258B2 Meter strip and method for lateral flow assay devices 有权
标题翻译：用于侧流测定装置的仪表条和方法
公开(公告)号：US07838258B2
公开(公告)日：2010-11-23
申请号：US12570713
申请日：2009-09-30
申请人： Kaiyuan Yang , Shawn R. Feaster , Ning Wei , Rosann M. Kaylor , Chibueze O. Chidebelu-Eze
发明人： Kaiyuan Yang , Shawn R. Feaster , Ning Wei , Rosann M. Kaylor , Chibueze O. Chidebelu-Eze
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： G01N33/54366 , B01L3/5023 , B01L2200/027 , B01L2300/0681 , B01L2300/0825 , B01L2300/0867 , B01L2400/0406 , B01L2400/0683 , G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331
摘要： A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.
摘要翻译：提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。套件包括壳体和设置在壳体内的膜，其具有检测区域和收集区域。提供血样计，其具有用于吸收血液样本的第一端，与第一端相邻的过滤部分，其从血液样品中过滤红细胞成分，以及与过滤部相邻的存储部，其接收血浆或血清从过滤部分。壳体中的开口的尺寸适于将样品计量器插入壳体中，使得样品计量器的存储部分设置成与膜的收集区域流体连通。将血浆或血清从样品计量器的储存部分转移到膜的收集区域，以便随后迁移到检测区域。

25. 发明授权

US07829328B2 Assay devices that utilize hollow particles 有权
标题翻译：使用中空颗粒的测定装置
公开(公告)号：US07829328B2
公开(公告)日：2010-11-09
申请号：US11440956
申请日：2006-05-25
申请人： Kaiyuan Yang , Ning Wei , Rosann Kaylor , Chibueze Obinna Chidebelu-Eze , Zdravko Savov Atanassov
发明人： Kaiyuan Yang , Ning Wei , Rosann Kaylor , Chibueze Obinna Chidebelu-Eze , Zdravko Savov Atanassov
IPC分类号： C12M1/34
CPC分类号： G01N33/587 , G01N33/558
摘要： Hollow particles for use in various types of assay devices are provided. Due to their hollow or voided structure, the particles may exhibit a variety of beneficial properties. For instance, hollow particles are generally lightweight, and thus, relatively inexpensive in comparison to other types of particles. Hollow particles may also form a stable system without requiring refrigeration or rotation. In addition, hollow particles may possess enhanced light diffraction capabilities, which may be particularly beneficial in certain types of assay devices, e.g., diffraction-based assay devices.
摘要翻译：提供了用于各种类型的测定装置的中空颗粒。由于其中空或空隙结构，颗粒可能表现出各种有益的性质。例如，中空颗粒通常是轻质的，因此与其它类型的颗粒相比相对便宜。中空颗粒也可以形成稳定的系统，而不需要制冷或旋转。此外，中空颗粒可以具有增强的光衍射能力，这在某些类型的测定装置中是特别有益的，例如基于衍射的测定装置。

26. 发明申请

US20100275915A1 METHOD FOR REDUCING ODOR USING COORDINATED POLYDENTATE COMPOUNDS 失效
标题翻译：使用协调的聚氨酯化合物减少气味的方法
公开(公告)号：US20100275915A1
公开(公告)日：2010-11-04
申请号：US12835418
申请日：2010-07-13
申请人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Do , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
发明人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Do , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
IPC分类号： A61L15/46 , A61L9/01 , A61L9/012 , C08F8/42 , A61M16/06
CPC分类号： D21H21/14 , A61L9/014 , A61L15/46 , A61L2300/102 , A61L2300/802
摘要： A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.
摘要翻译：提供了减少气味的方法。该方法包括在过渡金属和多齿化合物之间形成配位络合物，并使配位络合物与有气味化合物接触。过渡金属提供了一个或多个用于捕获有气味化合物的活性位点。在一些实施方案中，多齿化合物可以是聚烷基亚胺，例如聚乙烯亚胺，聚丙烯亚胺或其树枝状大分子。

27. 发明申请

US20090149772A1 Temperature Indicator for Cooling Products 审中-公开
标题翻译：冷却产品温度指示器
公开(公告)号：US20090149772A1
公开(公告)日：2009-06-11
申请号：US11950824
申请日：2007-12-05
申请人： J. Gavin MacDonald , Kaiyuan Yang , Kelly D. Arehart
发明人： J. Gavin MacDonald , Kaiyuan Yang , Kelly D. Arehart
IPC分类号： A61B5/01 , B32B5/16 , C09K5/00 , D04H13/00
CPC分类号： A61Q19/00 , A61K8/0204 , A61K8/0212 , A61K8/042 , A61K2800/244 , A61K2800/438 , A61K2800/884 , C09K5/00 , Y10T428/25 , Y10T442/60
摘要： A cooling product (e.g., mask, glove, sock, etc.) configured to provide a cooling effect to the body part of a user is provided. The cooling product contains a thermochromic composition that undergoes a color change at a certain temperature. The color change may signal to a user that the cooling product is cold, thus providing an indication that the desired treatment is still functioning. Likewise, the color change may signal that the product is warm, thus providing an indication that the treatment is complete.
摘要翻译：提供了一种被配置为向使用者的身体部位提供冷却效果的冷却产品（例如，面罩，手套，袜子等）。冷却产品含有在一定温度下经历颜色变化的热变色组合物。颜色变化可以向使用者发出冷却产品是冷的，从而提供所需治疗仍然起作用的指示。同样，颜色变化可能表示产品是温暖的，因此提供了处理完成的指示。

28. 发明申请

US20080026484A1 Metering Technique for Lateral Flow Assay Devices 有权
标题翻译：侧流测试装置的计量技术
公开(公告)号：US20080026484A1
公开(公告)日：2008-01-31
申请号：US11867788
申请日：2007-10-05
申请人： James Takeuchi , Xuedong Song , Kaiyuan Yang , Ning Wei , Shawn Feaster
发明人： James Takeuchi , Xuedong Song , Kaiyuan Yang , Ning Wei , Shawn Feaster
IPC分类号： G01N1/28 , G01N1/38
CPC分类号： G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331 , Y10T436/25375 , Y10T436/25625
摘要： A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the collection region having a known saturation volume for the intended test sample. A barrier is defined between the collection region and the detection region. The collection region is saturated with the test sample having a volume of less than about 100 microliters so that a known volume of the test sample is contained in the collection region. The barrier is removed from between the collection region and detection region of the membrane and a diluent is supplied to the collection region of the membrane to facilitate flow of the test sample from the collection region to the detection region of the membrane.
摘要翻译：提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。使用具有收集区域和检测区域的样品膜，所述收集区域具有用于预期测试样品的已知饱和体积。在收集区域和检测区域之间限定屏障。收集区域用体积小于约100微升的测试样品饱和，使得已知体积的测试样品被包含在收集区域中。从收集区域和膜的检测区域之间移除屏障，并且将稀释剂供应到膜的收集区域，以促进测试样品从收集区域流到膜的检测区域。

29. 发明申请

US20070000021A1 Stretchable and permeable non-woven protective gloves 有权
标题翻译：可伸展和可渗透的无纺布防护手套
公开(公告)号：US20070000021A1
公开(公告)日：2007-01-04
申请号：US11172607
申请日：2005-06-30
申请人： Kaiyuan Yang , Jeffrey Fish , Jason Baker , Oomman Thomas , Martin Shamis
发明人： Kaiyuan Yang , Jeffrey Fish , Jason Baker , Oomman Thomas , Martin Shamis
IPC分类号： A41D19/00
CPC分类号： A41D19/0006 , A41D19/0068
摘要： A protective glove is provided made substantially from a laminate material. The laminate material includes a plurality of elastic strands. A first nonwoven web is attached to the plurality of elastic strands so that in a relaxed state of the elastic strands and the first nonwoven web at least one wrinkle is formed in the first nonwoven web. A second nonwoven web is also provided and is attached to the plurality of elastic strands so that in a relaxed state of the elastic strands and the second nonwoven web at least one wrinkle is formed in the second nonwoven web. The elastic strands, first nonwoven web and second nonwoven web form a laminate that is stretchable and permeable to liquid. A method of manufacture of a protective glove is also provided.
摘要翻译：提供基本上由层压材料制成的保护手套。层压材料包括多根弹性线。第一非织造纤维网附接到多个弹性股线，使得在松弛状态的弹性股线和第一非织造纤维网中，在第一非织造纤维网中形成至少一个皱纹。还提供第二非织造纤维网并且附接到多个弹性股线，使得在松弛状态的弹性股线和第二非织造纤维网中，在第二非织造纤维网中形成至少一个皱纹。弹性股线，第一非织造纤维网和第二非织造纤维网形成对液体是可拉伸的和可渗透的层压体。还提供了一种制造防护手套的方法。

30. 发明申请

US20050136500A1 Flow-through assay devices 审中-公开
标题翻译：流通测定装置
公开(公告)号：US20050136500A1
公开(公告)日：2005-06-23
申请号：US10742590
申请日：2003-12-19
申请人： Kaiyuan Yang , RameshBabu Boga , Shawn Feaster , Rosann Marie Kaylor , David Cohen
发明人： Kaiyuan Yang , RameshBabu Boga , Shawn Feaster , Rosann Marie Kaylor , David Cohen
IPC分类号： G01N33/52 , G01N33/543 , G01N33/558 , C12Q1/54
CPC分类号： G01N33/558 , G01N33/52 , G01N33/5438
摘要： A flow-through assay device capable of detecting the presence or quantity of an analyte of interest is provided that is accurate, reliable, and easy-to-use. The device contains a substrate printed with a channel to facilitate the flow of a test sample to a detection working electrode. The detection working electrode communicates with affinity reagents, such as redox mediators and capture ligands. For instance, capture ligands that are specific binding members for the analyte of interest are applied to the detection electrode to serve as the primary location for detection of the analyte.
摘要翻译：提供了能够检测感兴趣的分析物的存在或数量的流通测定装置，其是准确，可靠和易于使用的。该装置包含印刷有通道以便于将测试样品流动到检测工作电极的基底。检测工作电极与亲和试剂如氧化还原介体和捕获配体连通。例如，将作为感兴趣的分析物的特异性结合成员的捕获配体施加到检测电极，以用作检测分析物的主要位置。

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