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21. 发明授权

US06842638B1 Angiography method and apparatus 失效
标题翻译：血管造影方法和装置
公开(公告)号：US06842638B1
公开(公告)日：2005-01-11
申请号：US10010773
申请日：2001-11-13
申请人： Jasjit S. Suri , Kecheng Liu , Dee H. Wu
发明人： Jasjit S. Suri , Kecheng Liu , Dee H. Wu
IPC分类号： A61B6/00 , G06T5/00 , G06T7/00 , G06T7/60 , A61B5/05
CPC分类号： G06T7/0012 , A61B6/481 , A61B6/504 , G06T7/12 , G06T7/149 , G06T7/64 , G06T2207/10088 , G06T2207/20064 , G06T2207/20161 , G06T2207/30101 , G06T2207/30172
摘要： A two-dimensional slice formed of pixels (376) is extracted from the angiographic image (76) after enhancing the vessel edges by second order spatial differentiation (78). Imaged vascular structures in the slice are located (388) and flood-filled (384). The edges of the filled regions are iteratively eroded to identify vessel centers (402). The extracting, locating, flood-filling, and eroding is repeated (408) for a plurality of slices to generate a plurality of vessel centers (84) that are representative of the vascular system. A vessel center (88) is selected, and a corresponding vessel direction (92) and orthogonal plane (94) are found. The vessel boundaries (710) in the orthogonal plane (94) are identified by iteratively propagating (704) a closed geometric contour arranged about the vessel center (88). The selecting, finding, and estimating are repeated for the plurality of vessel centers (84). The estimated vessel boundaries (710) are interpolated (770) to form a vascular tree (780).
摘要翻译：在通过二阶空间微分增强容器边缘之后，从血管造影图像（76）中提取由像素（376）形成的二维切片（78）。切片中的成像血管结构位于（388）和充满灌注（384）。填充区域的边缘被迭代地腐蚀以识别血管中心（402）。对于多个切片重复提取，定位，灌注和侵蚀（408），以产生代表血管系统的多个血管中心（84）。选择容器中心（88），并找到相应的容器方向（92）和正交平面（94）。在正交平面（94）中的血管边界（710）通过迭代地传播（704）围绕血管中心（88）布置的封闭几何轮廓来识别。对于多个血管中心（84）重复选择，发现和估计。估计的血管边界（710）被内插（770）以形成血管树（780）。

22. 发明授权

US06614453B1 Method and apparatus for medical image display for surgical tool planning and navigation in clinical environments 有权
标题翻译：用于临床环境中外科手术工具计划和导航的医学图像显示的方法和装置
公开(公告)号：US06614453B1
公开(公告)日：2003-09-02
申请号：US09565253
申请日：2000-05-05
申请人： Jasjit S. Suri , Ruhul Quddus , Yansun Xu
发明人： Jasjit S. Suri , Ruhul Quddus , Yansun Xu
IPC分类号： G06F300
CPC分类号： G06F19/321 , A61B34/20 , A61B34/25 , G06F19/00 , G16H50/50 , Y10S715/961
摘要： A medical imaging display system includes a memory (40) for storing first image data representative of a region of interest. The memory (40) stores image data generated by medical imaging devices such as magnetic resonance devices (20), computed tomography devices (22), nuclear imaging devices (26,28,30), and ultrasound devices. Typically, image data from these devices is obtained some time prior to a surgical event and users may access this data in planning for the surgical event. A processor (42), in data communication with the memory, is organized under a component object modeling architecture. The processor (42) is connected to a user interface (10) for providing user requests to the processor. Thus, in response to user action via the user interface (10), the processor (42) determines an object (54) adapted to act on the request, selects a handle (60) for the determined object and, employs the object via the handle to act on the request. Additionally, the image guided surgical system also includes a source (48) of substantially real time image data generated in the surgical theater, such as spectroscopy devices, which can also be manipulated via software objects to display desired portions of the region of interest. Any of these images can be viewed on a display (46) in a planning environment, in the surgical suite, or even by a consultant, geographically remote from the surgical site.
摘要翻译：医疗成像显示系统包括用于存储表示感兴趣区域的第一图像数据的存储器（40）。存储器（40）存储由诸如磁共振装置（20），计算机断层摄影装置（22），核成像装置（26,28,30）和超声装置之类的医疗成像装置产生的图像数据。通常，来自这些设备的图像数据在手术事件之前的一段时间获得，并且用户可以在规划外科事件时访问该数据。与存储器进行数据通信的处理器（42）被组织在组件对象建模架构下。处理器（42）连接到用户界面（10），用于向处理器提供用户请求。因此，响应于通过用户界面（10）的用户动作，处理器（42）确定适于作用于该请求的对象（54），为所确定的对象选择句柄（60），并且通过该对象根据要求处理。此外，图像引导手术系统还包括在手术室中生成的基本上实时的图像数据的源（48），例如光谱设备，其还可以经由软件对象来操纵以显示感兴趣区域的期望部分。这些图像中的任何一个都可以在规划环境，外科手术套件中的显示器（46）上，或者甚至可以在地理上远离手术部位的顾问进行观看。

23. 发明授权

US08805043B1 System and method for creating and using intelligent databases for assisting in intima-media thickness (IMT) 有权
标题翻译：用于创建和使用智能数据库以辅助内膜中厚度（IMT）的系统和方法
公开(公告)号：US08805043B1
公开(公告)日：2014-08-12
申请号：US12799177
申请日：2010-04-20
申请人： Jasjit S. Suri
发明人： Jasjit S. Suri
IPC分类号： G06K9/00 , A61B8/08
CPC分类号： A61B8/52 , A61B8/0891 , A61B8/5223 , G06T7/0012 , G06T2207/10132 , G06T2207/20016 , G06T2207/30101
摘要： A computer-based system for creating and using intelligent databases for assisting in intima-media thickness (IMT) measurements. Various embodiments utilize clinical data (images) to design intelligent clinical data sets, including geometric markers like blood vessel centerline, which can then be used with conventional image processing to compute the intima-media thickness of the carotid walls. The intelligent clinical image data utilizes the demographics (ethnity/race, gender and age) to classify the data. Finally, the intelligent database is used to collect intelligent parameters which are then applied to the incoming patients to estimate their intima-media thickness.
摘要翻译：一种基于计算机的系统，用于创建和使用智能数据库来协助内膜厚度（IMT）测量。各种实施例利用临床数据（图像）来设计智能临床数据集，包括像血管中心线的几何标记，其随后可以与常规图像处理一起使用以计算颈动脉壁的内膜 - 中膜厚度。智能临床图像数据利用人口统计学（种族/种族，性别和年龄）对数据进行分类。最后，智能数据库用于收集智能参数，然后将其应用于入院患者，以估计其内膜中层厚度。

24. 发明授权

US08639008B2 Mobile architecture using cloud for data mining application 失效
标题翻译：移动架构使用云进行数据挖掘应用
公开(公告)号：US08639008B2
公开(公告)日：2014-01-28
申请号：US13449518
申请日：2012-04-18
申请人： Jasjit S. Suri
发明人： Jasjit S. Suri
IPC分类号： G06K9/00
CPC分类号： A61B5/0013 , A61B5/0022 , A61B5/02007 , A61B5/055 , A61B6/5217 , A61B8/5223 , G06F19/00 , G06F19/321 , G16H10/60 , G16H50/20 , G16H50/30 , G16H50/70
摘要： Three tier architecture for image-based diagnosis and monitoring application using Cloud is described. The presentation layer is run on the tablet (mobile device), while the business and persistence layer runs on a single cloud or distributed on different Clouds in a multi-tenancy and multi-user application. Such architecture is used for automated data mining application for computing (a) cardiovascular risk, stroke risk using IMT measurement, plaque characterization, (b) computing diagnostic index for benign vs. malignant tissue for ovarian cancer classification (c) benign vs. malignant tissue characterization for prostate cancer and (d) classification of fatty liver disease vs. normal cases. The Architecture is for data mining application.
摘要翻译：描述了使用云的基于图像的诊断和监控应用的三层架构。表现层在平板电脑（移动设备）上运行，而业务和持久层在多租户和多用户应用程序中运行在单个云上或分布在不同的云上。这种架构用于计算自动化数据挖掘应用（a）使用IMT测量，斑块表征的心血管风险，卒中风险，（b）用于卵巢癌分类的良性与恶性组织的计算诊断指标（c）良性与恶性组织表征前列腺癌和（d）脂肪肝疾病与正常情况的分类。架构用于数据挖掘应用。

25. 发明申请

US20120203094A1 Mobile Architecture Using Cloud for Data Mining Application 失效
标题翻译：移动架构使用云进行数据挖掘应用
公开(公告)号：US20120203094A1
公开(公告)日：2012-08-09
申请号：US13449518
申请日：2012-04-18
申请人： Jasjit S. Suri
发明人： Jasjit S. Suri
IPC分类号： A61B5/055 , A61B8/00 , A61B6/00
CPC分类号： A61B5/0013 , A61B5/0022 , A61B5/02007 , A61B5/055 , A61B6/5217 , A61B8/5223 , G06F19/00 , G06F19/321 , G16H10/60 , G16H50/20 , G16H50/30 , G16H50/70
摘要： Three tier architecture for image-based diagnosis and monitoring application using Cloud is described. The presentation layer is run on the tablet (mobile device), while the business and persistence layer runs on a single cloud or distributed on different Clouds in a multi-tenancy and multi-user application. Such architecture is used for automated data mining application for computing (a) cardiovascular risk, stroke risk using IMT measurement, plaque characterization, (b) computing diagnostic index for benign vs. malignant tissue for ovarian cancer classification (c) benign vs. malignant tissue characterization for prostate cancer and (d) classification of fatty liver disease vs. normal cases. The Architecture is for data mining application.
摘要翻译：描述了使用云的基于图像的诊断和监控应用的三层架构。表现层在平板电脑（移动设备）上运行，而业务和持久层在多租户和多用户应用程序中运行在单个云上或分布在不同的云上。这种架构用于计算自动化数据挖掘应用（a）使用IMT测量，斑块表征的心血管风险，卒中风险，（b）用于卵巢癌分类的良性与恶性组织的计算诊断指标（c）良性与恶性组织表征前列腺癌和（d）脂肪肝疾病与正常情况的分类。架构用于数据挖掘应用。

26. 发明申请

US20120163693A1 Non-Invasive Imaging-Based Prostate Cancer Prediction 审中-公开
标题翻译：基于非侵入性成像的前列腺癌预测
公开(公告)号：US20120163693A1
公开(公告)日：2012-06-28
申请号：US13412118
申请日：2012-03-05
申请人： Jasjit S. Suri
发明人： Jasjit S. Suri
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/41 , G06T2207/10072 , G06T2207/10132 , G06T2207/20081 , G06T2207/30081
摘要： A system (UroImage™) is an imaging based system for predicting if the prostate is cancerous or not using non-invasive ultrasound. The method is an on-line system where region of interest processor computes the capsule region in the Urological image. The feature extraction processor finds the significant features such as non-linear higher order spectra and high pass filter discrete wavelet based features, and combines them. The on-line classifier processor uses along with the training-based parameters to estimate and predicate if the patient's prostate is cancerous or not. The UroImage™ also introduces the applicability of this system for MR, CT or fusion of these modalities with ultrasound for predicting cancer.
摘要翻译：系统（UroImage™）是一种基于成像的系统，用于使用非侵入性超声预测前列腺癌是否癌变。该方法是在线系统，其中感兴趣区域处理器计算泌尿图像中的胶囊区域。特征提取处理器发现诸如非线性高阶谱和基于离散小波的高通滤波特征的重要特征，并将其组合。在线分类器处理器与基于训练的参数一起使用，以估计和判断患者的前列腺是否癌变。 UroImage™还介绍了该系统对MR，CT或这些模式与超声波预测癌症融合的适用性。

27. 发明申请

US20120078099A1 Imaging Based Symptomatic Classification Using a Combination of Trace Transform, Fuzzy Technique and Multitude of Features 失效
标题翻译：使用跟踪变换，模糊技术和多种特征组合的基于成像的症状分类
公开(公告)号：US20120078099A1
公开(公告)日：2012-03-29
申请号：US13253952
申请日：2011-10-05
申请人： Jasjit S. Suri
发明人： Jasjit S. Suri
IPC分类号： A61B8/00
CPC分类号： A61B8/483 , A61B8/0891 , A61B8/12 , G01R33/5608
摘要： A statistical (a) Computer Aided Diagnostic (CAD) technique is described for symptomatic versus asymptomatic plaque automated classification of carotid ultrasound images and (b) presents a cardiovascular risk score computation. We demonstrate this for longitudinal Ultrasound, CT, MR modalities and extendable to 3D carotid Ultrasound. The on-line system consists of Atherosclerotic Wall Region estimation using AtheroEdge™ for longitudinal Ultrasound or Athero-CTView™ for CT or Athero-MRView from MR. This greyscale Wall Region is then fed to a feature extraction processor which uses the combination: (a) Higher Order Spectra; (b) Discrete Wavelet Transform (DWT); (c) Texture and (d) Wall Variability. Another combination uses: (a) Local Binary Pattern; (b) Law's Mask Energy and (c) Wall Variability. Another combination uses: (a) Trace Transform; (b) Fuzzy Grayscale Level Co-occurrence Matrix and (c) Wall Variability. The output of the Feature Processor is fed to the Classifier which is trained off-line.
摘要翻译：描述了用于颈动脉超声图像的症状与无症状斑块自动分类的统计学（a）计算机辅助诊断（CAD）技术，以及（b）呈现心血管风险评分计算。我们展示了纵向超声，CT，MR方式，并可扩展到三维颈动脉超声。在线系统由动脉粥样硬化壁区域估计，使用AtheroEdge™进行纵向超声波或用于CT的Athero-CTView™或来自MR的Athero-MRView。然后将这个灰度级的墙区域馈送到使用以下组合的特征提取处理器：（a）高阶光谱; （b）离散小波变换（DWT）; （c）纹理和（d）壁变化。另一种组合使用：（a）本地二进制模式; （b）法律面具能量和（c）墙面变异性。另一种组合使用：（a）轨迹变换; （b）模糊灰度等级共生矩阵和（c）墙壁变异性。特征处理器的输出被馈送到离线训练的分类器。

28. 发明申请

US20100172559A1 SYSTEM AND METHOD FOR PROSTATE BIOPSY 审中-公开
标题翻译：用于预测生物的系统和方法
公开(公告)号：US20100172559A1
公开(公告)日：2010-07-08
申请号：US12615862
申请日：2009-11-10
申请人： Dinesh Kumar , Jasjit S. Suri
发明人： Dinesh Kumar , Jasjit S. Suri
IPC分类号： G06K9/00
CPC分类号： A61B10/0241 , A61B34/20 , A61B2090/3782 , G06T7/33 , G06T2207/10072 , G06T2207/10132 , G06T2207/30056 , G06T2207/30068 , G06T2207/30081 , G06T2207/30084
摘要： The invention presents tools to improve a 3-D image aided biopsy or treatment procedure for prostate gland by providing additional functionality and additional visual cues on an output image of the prostate, which may be generated substantially in real-time. The tools include i) the identification of various parts of prostate to classify as per regular classification in pathological reports, ii) Computing and displaying the insertion depth of needle with respect to a selected target point during the procedure, iii) Computing and displaying the distance from needle tip to prostate surface following a procedure and, iv) Calibration for misalignment of a 2-D imaging transducer when used under tracked motion for a procedure.
摘要翻译：本发明提供了通过在前列腺的输出图像上提供附加功能和附加视觉提示来实质上实时地产生用于改善前列腺的3-D图像辅助活组织检查或治疗过程的工具。这些工具包括：i）根据病理报告中的常规分类对前列腺各部分进行鉴定，ii）在手术过程中计算和显示相对于选定目标点的针插入深度，iii）计算和显示距离根据程序从针尖到前列腺表面，以及iv）当在跟踪运动下用于程序时，对2-D成像换能器的未对准进行校准。

29. 发明申请

US20100111379A1 Method for breast screening in fused mammography 有权
标题翻译：融合乳房X线照相术中乳房筛查的方法
公开(公告)号：US20100111379A1
公开(公告)日：2010-05-06
申请号：US11632078
申请日：2005-07-07
申请人： Jasjit S. Suri , Yajie Sun
发明人： Jasjit S. Suri , Yajie Sun
IPC分类号： G06K9/00
CPC分类号： A61B6/5247 , A61B6/032 , A61B6/4417 , A61B6/502 , A61B6/52 , A61B6/5217 , A61B8/0825 , A61B8/4416 , A61B8/5238 , G06T7/0012 , G06T7/0081 , G06T7/0091 , G06T7/11 , G06T7/12 , G06T7/155 , G06T7/168 , G06T11/003 , G06T2207/10112 , G06T2207/10116 , G06T2207/10136 , G06T2207/20016 , G06T2207/20076 , G06T2207/20168 , G06T2207/30068 , G06T2207/30096
摘要： A method for use in medical imaging of a patient including, with the patient immobilized with respect to an imaging reference frame, acquiring first digital imaging information including a first region of interest using a first imaging modality; processing the first digital imaging information to identify a feature for analysis; and using a second imaging modality to acquire targeted second imaging information for a second region of interest, the second region of interest corresponding to a subset of the first region of interest, wherein the second region of interest includes the feature for analysis. An apparatus for use in medical imaging comprising structure for immobilizing a patient with respect to an imaging reference frame; a first imaging system for acquiring first digital imaging information including a first region of interest using a first imaging modality; a processor processing the first digital imaging information using a diagnostic tool to identify a feature of interest; and a second imaging system for acquiring second imaging information using a second imaging modality, the second imaging information corresponding to a second region of interest including the feature for analysis.
摘要翻译：一种用于患者的医学成像的方法，包括：相对于成像参考系被固定的患者，使用第一成像模态获取包括第一感兴趣区域的第一数字成像信息; 处理第一数字成像信息以识别用于分析的特征; 以及使用第二成像模式来获取第二感兴趣区域的目标第二成像信息，所述第二感兴趣区域对应于所述第一感兴趣区域的子集，其中所述第二感兴趣区域包括用于分析的特征。一种用于医学成像的装置，包括用于使患者相对于成像参考框架固定的结构; 第一成像系统，用于使用第一成像模态获取包括第一感兴趣区域的第一数字成像信息; 处理器使用诊断工具处理所述第一数字成像信息，以识别感兴趣的特征; 以及第二成像系统，用于使用第二成像模式获取第二成像信息，所述第二成像信息对应于包括用于分析的特征的第二感兴趣区域。

30. 发明申请

US20100016710A1 PROSTATE TREATMENT APPARATUS 审中-公开
标题翻译：前台处理装置
公开(公告)号：US20100016710A1
公开(公告)日：2010-01-21
申请号：US12501943
申请日：2009-07-13
申请人： Dinesh Kumar , Jasjit S. Suri
发明人： Dinesh Kumar , Jasjit S. Suri
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B8/0833 , A61B8/0841 , A61B8/12 , A61B8/483 , A61B8/5223 , A61B18/02 , A61B18/08 , A61B2018/00547 , A61B2018/00577 , A61B2034/2063 , A61B2090/3784 , A61N5/1001 , A61N2005/1012 , A61N2005/1058
摘要： The presented invention aims to address these and/or additional issues by providing a tracked grid for brachytherapy applications that can adjust to changes in the prostate between original image acquisition. The grid is allowed to be moved around and even rotated under tracked conditions, such that it can be maneuvered to align with any target region. A virtual 3-D grid is displayed on a computer with respect to the actual anatomy of the patient. The tracked grid can be moved relative to the virtual 3-D grid, such that the brachytherapy, cryo therapy or any other type of image guided therapy may be performed in real 3-D or even 4-D, when motion compensation is embedded during the procedure.
摘要翻译：所提出的发明旨在通过提供一种用于近距离放射治疗应用的跟踪网格来解决这些和/或另外的问题，其可以适应原始图像采集之前的前列腺的变化。允许网格被移动并且甚至在跟踪条件下旋转，使得其可以被操纵以与任何目标区域对齐。相对于患者的实际解剖结构，在计算机上显示虚拟3-D网格。跟踪的网格可以相对于虚拟3-D网格移动，使得当在3-D或甚至4-D中嵌入运动补偿时，近距离放射治疗，低温治疗或任何其他类型的图像引导治疗可以被执行步骤。

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