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21. 发明授权

US09286671B2 Method for determining at least one applicable path of movement for an object in tissue 有权
标题翻译：用于确定组织中的物体的至少一个运动路径的方法
公开(公告)号：US09286671B2
公开(公告)日：2016-03-15
申请号：US13979150
申请日：2012-01-13
申请人： Ahmet Ekin , Hubert Cecile Francois Martens
发明人： Ahmet Ekin , Hubert Cecile Francois Martens
IPC分类号： G06K9/00 , G06T7/00 , A61B17/34 , A61B19/00 , G06T15/08 , G06F19/00
CPC分类号： G06T7/0012 , A61B17/3403 , A61B34/10 , A61B90/11 , A61B90/36 , A61B2034/107 , G06F19/00 , G06F19/321 , G06T15/08 , G06T2207/10081 , G06T2207/10088 , G06T2207/10136 , G06T2207/30016 , G06T2207/30241 , G16H50/20 , G16H50/50
摘要： A method for determining an applicable path of movement of an object in human or animal tissue is based on intensity data obtained by a 3D imaging technique. The applicable path of movement connects a starling position of the object with a defined target location. The method includes defining the target location of a reference point of the object and choosing at least one possible starting position of the reference point of the object. Further, the method includes determining a candidate path of movement between the corresponding possible starling position and the defined target location. Next, the candidate path of movement is evaluated for being an applicable path. The candidate path is evaluated based on information about local intensity extrema and/or intensity variation resulting from the intensity data along the candidate path of movement.
摘要翻译：用于确定人体或动物组织中的物体的运动路径的方法是基于通过3D成像技术获得的强度数据。适用的运动路径将物体的星空位置与定义的目标位置相连。该方法包括定义对象的参考点的目标位置并选择对象的参考点的至少一个可能的起始位置。此外，该方法包括确定在相应的可能椋鸟位置和所定义的目标位置之间的候选移动路径。接下来，评估候选运动路径作为适用路径。基于从候选移动路径的强度数据产生的局部强度极值和/或强度变化的信息来评估候选路径。

22. 发明授权

US09020604B2 Multi-electrode neurostimulation device 有权
标题翻译：多电极神经刺激装置
公开(公告)号：US09020604B2
公开(公告)日：2015-04-28
申请号：US13285084
申请日：2011-10-31
申请人： Hubert Cecile Francois Martens
发明人： Hubert Cecile Francois Martens
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36139 , A61N1/0531 , A61N1/0553 , A61N1/36146 , A61N1/36157 , A61N1/36182 , A61N1/36185
摘要： A neurostimulation device is provided comprising an input, a neurostimulation probe, a stimulation unit and a distribution calculation module. At the input stimulation data is received comprising information relating to a stimulation preferability and an orientation of at least one fiber bundle. The neurostimulation probe comprises an array of stimulation electrodes which are coupled to the stimulation unit. The stimulation unit, in accordance with a specified current distribution, provides currents to the respective stimulation electrodes for generating an electric field gradient. The distribution calculation module is coupled to the input and the stimulation unit for based on the stimulation data determining a preferred position and orientation for the electric field gradient, and based on the preferred position and orientation for the electric field gradient, calculating the specified current distribution.
摘要翻译：提供神经刺激装置，其包括输入，神经刺激探针，刺激单元和分布计算模块。在输入刺激数据被接收包括与刺激优选性和至少一个纤维束的取向有关的信息。神经刺激探针包括耦合到刺激单元的刺激电极的阵列。刺激单元根据指定的电流分布，向相应的刺激电极提供电流以产生电场梯度。分布计算模块基于确定电场梯度的优选位置和取向的刺激数据耦合到输入和刺激单元，并且基于电场梯度的优选位置和取向，计算指定的电流分布。

23. 发明授权

US08942446B2 System and method for planning a neurosurgical operation 有权
标题翻译：用于规划神经外科手术的系统和方法
公开(公告)号：US08942446B2
公开(公告)日：2015-01-27
申请号：US13640490
申请日：2011-04-08
申请人： Hubert Cecile Francois Martens
发明人： Hubert Cecile Francois Martens
IPC分类号： G06K9/00 , G06F19/00
CPC分类号： G06F19/3437 , G06F19/00 , G06F19/3481 , G16H50/50
摘要： A system (10) and method (20) for planning a neurosurgical operation are provided the system (10) comprises an input (11) for receiving functional data (25) and anatomical data of a brain region (31), and a processor (12) configured to perform the method (20) according to the invention. The method (20) comprises analyzing (26) the functional data (25) to form a network representation (27) of functional connections, mapping the network representation (27) of the functional connections and the anatomical data to a common coordinate system, determining an expected function loss associated with a simulated removal of network nodes (32) or network connections (42) from the network representation (27), and identifying critical network connections and/or critical network nodes based on the expected function loss.
摘要翻译：提供了一种用于规划神经外科手术的系统（10）和方法（20），所述系统（10）包括用于接收功能数据（25）的输入端（11）和脑区域（31）的解剖数据，以及处理器 12），其被配置为执行根据本发明的方法（20）。方法（20）包括分析（26）功能数据（25）以形成功能连接的网络表示（27），将功能连接的网络表示（27）和解剖数据映射到公共坐标系，确定与来自网络表示（27）的网络节点（32）或网络连接（42）的模拟移除相关联的预期功能损失，以及基于预期功能损失来识别关键网络连接和/或关键网络节点。

24. 发明授权

US08831307B2 Visualizing surgical trajectories 有权
标题翻译：可视化手术轨迹
公开(公告)号：US08831307B2
公开(公告)日：2014-09-09
申请号：US13378094
申请日：2010-06-21
申请人： Hayriye Cagnan , Hubert Cecile Francois Martens , Kevin Thomas Dolan
发明人： Hayriye Cagnan , Hubert Cecile Francois Martens , Kevin Thomas Dolan
IPC分类号： G06K9/00 , A61B19/00
CPC分类号： A61B19/50 , A61B34/10 , A61B34/20 , A61B2034/105 , A61B2034/107 , A61B2090/364 , A61B2090/3762
摘要： A method is provided for visualizing a surgical trajectory (32, 101, 42, 46, 47). The method comprises steps of receiving (71) 3D imaging information (31) of a region to undergo surgery and combining (72) the received 3D imaging information (31) with data from a digitized anatomical atlas. As a result, a combined map of the region to undergo surgery is obtained. The combined map comprises expected positions of anatomical structures (102, 103, 104) in the region to undergo surgery. The method further comprises steps of receiving (73) the surgical trajectory (32, 101, 42, 46, 47) for the surgery, determining (74) positions of intersections (43, 44) of the surgical trajectory (32, 101, 42, 46, 47) with the anatomical structures (102, 103, 104) and providing (75) the positions of the intersections (43, 44) in a coordinate system aligned with the surgical trajectory (32, 101, 42, 46, 47).
摘要翻译：提供了一种用于可视化手术轨迹（32,101,42,46,47）的方法。该方法包括以下步骤：接收（71）区域的3D成像信息（31）以进行手术并将接收的3D成像信息（31）与来自数字化解剖图谱的数据组合（72）。结果，获得了进行手术的区域的组合图。组合图包括在进行手术的区域中的解剖结构（102,103,104）的预期位置。该方法还包括以下步骤：接收（73）用于手术的手术轨迹（32,101,42,46,47），确定手术轨迹（32,101,42）的交叉点（43,44）的位置（74），46,47），其具有解剖结构（102,103,104），并且提供（75）所述交叉点（43,44）在与所述外科轨迹（32,101,42,46,47）对准的坐标系中的位置）。

25. 发明授权

US08477578B2 Multi-speed recording for multi-layer disc 失效
标题翻译：多层光盘多段录像
公开(公告)号：US08477578B2
公开(公告)日：2013-07-02
申请号：US13017234
申请日：2011-01-31
申请人： Ronald Van Den Oetelaar , Hubert Cecile Francois Martens , Wilhelmus Robert Koppers , Pierre Hermanus
发明人： Ronald Van Den Oetelaar , Hubert Cecile Francois Martens , Wilhelmus Robert Koppers , Pierre Hermanus
IPC分类号： G11B7/00
CPC分类号： G11B7/0045 , G11B7/00456 , G11B7/00736 , G11B7/24038 , G11B2007/0013
摘要： The present invention relates to a recording apparatus, record carrier and method of recording data on at least two layers of a recording medium by using a radiation power, wherein individual recording speeds are determined for respective ones of the at least two layers at different values of the radiation power. A recording speed to be used for recording on an individual one of the at least two recording layers is selected based on a maximum radiation power specified for the recording operation, and the speed of the recording operation is controlled individually for each of the at least two layers based on the selected recording speed. The determination of the individual recording speeds at different radiation power values may be written or embossed on the record carrier. Furthermore, a recording sequence used for recording on the recording layers can be set based on the sensitivities and thus recording speeds. Thereby, total recording time can be minimized for multi-layer recording media.
摘要翻译：本发明涉及一种通过使用辐射功率在至少两层记录介质上记录数据的记录装置，记录载体和方法，其中针对所述至少两个层中的不同值确定各个记录速度辐射功率。基于为记录操作指定的最大辐射功率来选择用于记录在至少两个记录层中的单个记录层上的记录速度，并且对于至少两个记录层中的每一个单独地控制记录操作的速度基于所选记录速度的层。在不同辐射功率值下的单个记录速度的确定可以被写入或压印在记录载体上。此外，可以基于灵敏度和因此记录速度来设置用于记录层上的记录的记录顺序。因此，对于多层记录介质，总记录时间可以最小化。

26. 发明申请

US20120099770A1 VISUALIZING SURGICAL TRAJECTORIES 有权
标题翻译：可视化外科手术
公开(公告)号：US20120099770A1
公开(公告)日：2012-04-26
申请号：US13378094
申请日：2010-06-21
申请人： Hayriye Cagnan , Hubert Cecile Francois Martens , Kevin Thomas Dolan
发明人： Hayriye Cagnan , Hubert Cecile Francois Martens , Kevin Thomas Dolan
IPC分类号： G06K9/00
CPC分类号： A61B19/50 , A61B34/10 , A61B34/20 , A61B2034/105 , A61B2034/107 , A61B2090/364 , A61B2090/3762
摘要： A method is provided for visualizing a surgical trajectory (32, 101, 42, 46, 47). The method comprises steps of receiving (71) 3D imaging information (31) of a region to undergo surgery and combining (72) the received 3D imaging information (31) with data from a digitized anatomical atlas. As a result, a combined map of the region to undergo surgery is obtained. The combined map comprises expected positions of anatomical structures (102, 103, 104) in the region to undergo surgery. The method further comprises steps of receiving (73) the surgical trajectory (32, 101, 42, 46, 47) for the surgery, determining (74) positions of intersections (43, 44) of the surgical trajectory (32, 101, 42, 46, 47) with the anatomical structures (102, 103, 104) and providing (75) the positions of the intersections (43, 44) in a coordinate system aligned with the surgical trajectory (32, 101, 42, 46, 47).
摘要翻译：提供了一种用于可视化手术轨迹（32,101,42,46,47）的方法。该方法包括以下步骤：接收（71）区域的3D成像信息（31）以进行手术并将接收的3D成像信息（31）与来自数字化解剖图谱的数据组合（72）。结果，获得了进行手术的区域的组合图。组合图包括在进行手术的区域中的解剖结构（102,103,104）的预期位置。该方法还包括以下步骤：接收（73）用于手术的手术轨迹（32,101,42,46,47），确定手术轨迹（32,101,42）的交叉点（43,44）的位置（74），46,47），其具有解剖结构（102,103,104），并且提供（75）所述交叉点（43,44）在与所述外科轨迹（32,101,42,46,47）对准的坐标系中的位置）。

27. 发明授权

US07764591B2 Multilayer optical disc having a recording stack type indicator 有权
标题翻译：具有记录堆叠型指示器的多层光盘
公开(公告)号：US07764591B2
公开(公告)日：2010-07-27
申请号：US10527120
申请日：2003-08-28
申请人： Benno Tieke , Jakob Gerrit Nijboer , Hubert Cecile Francois Martens
发明人： Benno Tieke , Jakob Gerrit Nijboer , Hubert Cecile Francois Martens
IPC分类号： G11B7/24
CPC分类号： G11B7/1263 , G11B7/00456 , G11B7/00736 , G11B7/24038 , G11B19/127
摘要： A multilayer record carrier of a writable type has a first recording layer (40) having a first recording stack (50,51) of a first type and a second recording layer (41) having a second recording stack (54,55) of a second type. The first and second recording stacks have different writing parameters. Each recording layer has a pre-formed recording control pattern that is readable via a laser beam for indicating the track. At least one recording control pattern comprises a recording stack type indicator for indicating the writing parameters of the second recording stack. A recording device has a control unit (20) for adjusting recording parameters in the device in dependence of the recording stack type indicator retrieved from the recording control pattern.
摘要翻译：可写类型的多层记录载体具有第一记录层（40），其具有第一类型的第一记录堆叠（50,51）和具有第二记录层（54,55）的第一记录层（41）第二种。第一和第二记录堆栈具有不同的写入参数。每个记录层具有经由用于指示轨道的激光束可读的预先形成的记录控制图案。至少一个记录控制模式包括用于指示第二记录堆叠的写入参数的记录堆栈类型指示符。记录装置具有控制单元（20），用于根据从记录控制模式检索的记录堆叠类型指示器来调节设备中的记录参数。

28. 发明申请

US20100030298A1 TISSUE STIMULATION METHOD AND APPARATUS 有权
标题翻译：组织刺激方法和装置
公开(公告)号：US20100030298A1
公开(公告)日：2010-02-04
申请号：US12442862
申请日：2007-09-21
申请人： Hubert Cecile Francois Martens , Michel Marcel Jose Decre , Eugenio Cantatore
发明人： Hubert Cecile Francois Martens , Michel Marcel Jose Decre , Eugenio Cantatore
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0529 , A61N1/0472 , A61N1/0476 , A61N1/05
摘要： A stimulation apparatus includes a stimulation lead (102), a multiplexer (114), a stimulation signal generator (116), and a signal detector (120). The stimulation lead (102) includes a plurality of stimulation electrodes (112) disposed in an array about a distal portion of the lead body (110). The arrangement of the electrodes (112) facilitates the controlled steering of stimulating electrical field (118) in three dimensions. Four dimensional field steering may also be provided.
摘要翻译：刺激装置包括刺激引线（102），多路复用器（114），刺激信号发生器（116）和信号检测器（120）。刺激引线（102）包括围绕引线主体（110）的远端部分排列成阵列的多个刺激电极（112）。电极（112）的布置有助于三维地控制刺激电场（118）的转向。还可以提供四维场转向。

29. 发明授权

US07360228B2 Multi-stack optical data storage medium and use of such medium 有权
标题翻译：多层光学数据存储介质和这种介质的使用
公开(公告)号：US07360228B2
公开(公告)日：2008-04-15
申请号：US10525578
申请日：2003-08-14
申请人： Ronald Joseph Antonius Van Den Oetelaar , Hubert Cecile Francois Martens
发明人： Ronald Joseph Antonius Van Den Oetelaar , Hubert Cecile Francois Martens
IPC分类号： G11B7/24 , G11B7/242
CPC分类号： G11B7/24038 , G11B7/00455 , G11B7/24 , G11B7/24062 , G11B7/246 , G11B2007/0013 , G11B2220/235 , G11B2220/2562
摘要： A multi-stack optical data storage medium, for recording using a focused radiation beam having a wavelength λ and entering through an entrance face of the medium, has a first substrate having a first guide groove formed therein, and a first recording stack including a recordable type recording layer having a thickness dL0G in the groove and a thickness dL0L adjacent the groove. A second substrate has a second guide groove formed therein, and a second recording stack including a recordable type recording layer having a thickness dL1G in the groove and a thickness dL1L adjacent the groove. The second recording stack is at a position closer to the entrance face than the first recording stack. The depth of the first guide groove is smaller than 0.15λ and dL0L is substantially equal to or larger than dL1G.
摘要翻译：一种用于使用具有波长λ并通过介质的入射面进入的聚焦辐射束进行记录的多层光学数据存储介质，具有形成在其中的第一引导槽的第一基板和包括可记录的第一记录堆叠的第一记录堆叠在凹槽中具有厚度d L0G 的类型记录层和与凹槽相邻的厚度dLLL 。第二基板具有形成在其中的第二引导槽，并且第二记录堆叠包括在槽中具有厚度d L1> L1G的可记录型记录层和相邻的厚度d L1L < 凹槽第二记录堆叠处于比第一记录堆叠更靠近入口面的位置。第一引导槽的深度小于0.15λ，并且dLLL大体上等于或大于dL1G 。

30. 发明授权

US09387318B2 Tissue stimulation method and apparatus 有权
标题翻译：组织刺激方法和装置
公开(公告)号：US09387318B2
公开(公告)日：2016-07-12
申请号：US12442862
申请日：2007-09-21
申请人： Hubert Cecile Francois Martens , Michel Marcel Jose Decre , Eugenio Cantatore
发明人： Hubert Cecile Francois Martens , Michel Marcel Jose Decre , Eugenio Cantatore
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/0529 , A61N1/0472 , A61N1/0476 , A61N1/05
摘要： A stimulation apparatus includes a stimulation lead (102), a multiplexer (114), a stimulation signal generator (116), and a signal detector (120). The stimulation lead (102) includes a plurality of stimulation electrodes (112) disposed in an array about a distal portion of the lead body (110). The arrangement of the electrodes (112) facilitates the controlled steering of stimulating electrical field (118) in three dimensions. Four dimensional field steering may also be provided.
摘要翻译：刺激装置包括刺激引线（102），多路复用器（114），刺激信号发生器（116）和信号检测器（120）。刺激引线（102）包括围绕引线主体（110）的远端部分排列成阵列的多个刺激电极（112）。电极（112）的布置有助于三维地控制刺激电场（118）的转向。还可以提供四维场转向。

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