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21. 发明申请

US20110245581A1 METHOD AND APPARATUS FOR THROMBUS REMOVAL USING MAGNETIC PARTICLES 审中-公开
标题翻译：使用磁性颗粒去除血红蛋白的方法和装置
公开(公告)号：US20110245581A1
公开(公告)日：2011-10-06
申请号：US13163977
申请日：2011-06-20
申请人： David Eric Schwartz , Scott A. Elrod , Richard H. Bruce , Daniel L. Larner
发明人： David Eric Schwartz , Scott A. Elrod , Richard H. Bruce , Daniel L. Larner
IPC分类号： A61N2/10
CPC分类号： A61N2/004 , A61N2/06
摘要： A method and system for affecting a thrombus after ischemic stroke. The method may include injecting a plurality of magnetic particles into a bloodstream and moving or distorting a thrombus formed or lodged in the bloodstream using a magnetic force to manipulate the magnetic particles. The method may include conjugating ferromagnetic particles, paramagnetic particles, or superparamagnetic particles to a thrombus-specific attachment agent such as an anti-fibrin antibody, and injecting the conjugated particles into the bloodstream. Thereafter, the thrombus may be agitated, broken apart, or dissolved using a magnetic field to exert a magnetic force on the conjugated particles. The method may also include injecting a thrombolytic agent into the bloodstream to interact with and further dissolve the thrombus.
摘要翻译：缺血性卒中后影响血栓的方法和系统。该方法可以包括将多个磁性颗粒注入血液流中，并使用磁力来移动或扭曲在血流中形成或储存的血栓来操纵磁性颗粒。该方法可以包括将铁磁性颗粒，顺磁性颗粒或超顺磁性颗粒结合到血栓特异性附着剂如抗纤维蛋白抗体，并将缀合的颗粒注入血流中。此后，可以使用磁场搅动，断开或溶解血栓，以对共轭颗粒施加磁力。该方法还可以包括将血栓溶解剂注射到血流中以与血栓相互作用并进一步溶解血栓。

22. 发明申请

US20110082353A1 Implanting Optical Cavity Structures 有权
标题翻译：植入光腔结构
公开(公告)号：US20110082353A1
公开(公告)日：2011-04-07
申请号：US12968115
申请日：2010-12-14
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Richard H. Bruce , Noble M. Johnson
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Richard H. Bruce , Noble M. Johnson
IPC分类号： A61B5/00
CPC分类号： G01N21/03 , A61B5/0075 , A61B5/0084 , A61B5/14532 , A61B5/1459 , G01N21/0303 , G01N21/274 , G01N21/31
摘要： An implantable product includes an optical cavity structure with first and second parts, each of which can operate as an optical cavity. The first part includes a container with at least one opening through which bodily fluid can transfer between the container's interior and exterior when the product is implanted in a body. The second part includes a container that is closed and contains a reference fluid. The implantable product can also include one or both of a light source component and a photosensing component. Photosensed quantities from the first part's output light can be adjusted based on photosensed quantities from the second part's output light. Both parts can have their light interface surfaces aligned so that they both receive input light from a light source component and both provide output light to a photosensing component.
摘要翻译：可植入产品包括具有第一和第二部分的光学腔结构，每个部分可以作为光腔工作。第一部分包括具有至少一个开口的容器，当产品植入体内时，体液可以通过该开口在容器的内部和外部之间转移。第二部分包括封闭的容器并且包含参考流体。可植入产品还可以包括光源组件和感光组件中的一个或两个。可以根据第二部分输出指示灯的光线数量来调整第一部分输出光的照片数量。两个部件可以使它们的光接口表面对准，使得它们都接收来自光源部件的输入光并且都向光敏部件提供输出光。

23. 发明申请

US20080313036A1 System and method for providing advertisements in online and hardcopy mediums 审中-公开
标题翻译：在网络和硬拷贝媒体中提供广告的系统和方法
公开(公告)号：US20080313036A1
公开(公告)日：2008-12-18
申请号：US11818439
申请日：2007-06-13
申请人： Marc Mosko , Richard H. Bruce , Nitin Parekh , James (Bo) M.A. Begole , Lisa Fahey , Eric Peeters
发明人： Marc Mosko , Richard H. Bruce , Nitin Parekh , James (Bo) M.A. Begole , Lisa Fahey , Eric Peeters
IPC分类号： G06Q30/00 , G06Q40/00
CPC分类号： G06Q30/02 , G06Q20/10 , G06Q30/0242 , G06Q30/0251 , G06Q30/0256 , G06Q30/0277
摘要： A system and method for providing advertisements in online and hardcopy mediums is presented. Advertising content is targeted to a target audience. The characteristics of the target audience are analyzed against the advertising content to identify potential advertisers. At least one of the potential advertisers is selected. One or more advertisements for the selected advertiser is included on a document. The document is provided on at least one of online and hardcopy mediums.
摘要翻译：提出了一种在网络和硬拷贝介质中提供广告的系统和方法。广告内容针对目标受众。根据广告内容分析目标受众的特征，以识别潜在的广告客户。至少有一个潜在的广告客户被选中。所选择的广告商的一个或多个广告被包括在文档上。该文档至少提供在线和硬拷贝介质之一。

24. 发明授权

US5897097A Passively addressable fluid valves having S-shaped blocking films 失效
标题翻译：具有S形阻挡膜的被动寻址流体阀
公开(公告)号：US5897097A
公开(公告)日：1999-04-27
申请号：US711299
申请日：1996-09-06
申请人： David K. Biegelsen , Patrick C. P. Cheung , Andrew A. Berlin , Warren B. Jackson , Lars-Erik Swartz , Raj B. Apte , Richard H. Bruce
发明人： David K. Biegelsen , Patrick C. P. Cheung , Andrew A. Berlin , Warren B. Jackson , Lars-Erik Swartz , Raj B. Apte , Richard H. Bruce
IPC分类号： B65H5/22 , B65H29/24 , F15C5/00 , F16K31/02
CPC分类号： F15C5/00 , Y10S251/901 , Y10T137/87249
摘要： A bistable valve useful for paper handling applications is disclosed. The valve can be batch fabricated in two dimensional valve arrays, with each valve in the array being controlled by passive matrix addressing. Typically, each valve includes a valve housing having an aperture plate defining an aperture therethrough, and an opposing plate positioned in spaced apart relationship to the aperture plate. A flexible film or strip is attached at its first end to the aperture plate and at its second end to the opposing plate. Valve action is provided by use of at least two switching electrodes for moving the flexible film between an aperture blocking position and an aperture open position, with at least one of the switching electrodes positioned adjacent to the aperture plate and at least one of the switching electrodes positioned adjacent to the opposing plate. To reduce unswitched movement when the switching electrode bias is reduced or not present, at least two electrostatic or mechanical catches are used.
摘要翻译：公开了一种用于纸张处理应用的双稳态阀。阀门可以批量制造在二维阀门阵列中，阵列中的每个阀门都被无源矩阵寻址控制。通常，每个阀包括具有限定穿过其中的孔的孔板的阀壳体和与孔板间隔开的关系。柔性膜或带在其第一端附接到孔板并且在其第二端附接到相对的板。通过使用至少两个开关电极来提供阀动作，所述至少两个开关电极用于在孔闭阻位置和孔打开位置之间移动柔性膜，其中至少一个开关电极位于孔板附近，并且至少一个开关电极定位在相对的板附近。为了在开关电极偏压减小或不存在时减少非开关动作，使用至少两个静电或机械捕捉。

25. 发明授权

US5504598A Large screen full color display with plural adjacent display panels and enlarging graded index lens array 失效
标题翻译：大屏幕全彩显示屏，多个相邻的显示面板和放大的渐变折射率透镜阵列
公开(公告)号：US5504598A
公开(公告)日：1996-04-02
申请号：US450071
申请日：1995-05-25
申请人： Robert A. Sprague , Richard H. Bruce , Louis D. Silverstein
发明人： Robert A. Sprague , Richard H. Bruce , Louis D. Silverstein
IPC分类号： G02B3/00 , G02F1/1335 , G02F1/13357 , G09G3/18 , H04N9/30
CPC分类号： G02B3/0056 , G02F1/133526 , G02F1/133617 , G02B3/0031 , G02B3/0062 , G02B3/0087
摘要： A full color display is disclosed having a high efficiency light source optically coupled by a light coupling lens array to the active matrix of pixel elements of an image forming means such as a transmissive liquid crystal light valve. The light source is comprised of a patterned matrix of individual, primary colored visible radiation emitters, such as individual phosphor elements, arranged in a manner suitable for the human eye to integrate the individual primary colored lights into a single mixture color. The light coupling lens array collects substantially all of the light rays emitted from each primary colored light emitter and focuses them on a respective one of the transparent electrodes in the active matrix, as a real image smaller than the size of the electrode. A suitable light coupling lens array is a gradient index lens array, a multiple layer, two dimensional array of microlenses functionally analogous to an array of strip lenses, or a microlens array. A twisted nematic liquid crystal cell may be used in the image forming means to achieve a high contrast display. Use of the light coupling lens array to collect and focus the light rays from the light source permits the focused light to pass through an entrance polarizer with minimal scattering or divergence, and then through the respective transparent electrode in the active matrix unobscured by the opaque pixel interconnect elements. More efficient use of a larger percentage of the light from the light source in this manner results in the formation of a bright, high contrast, full color image.
摘要翻译：公开了一种全色显示器，其具有通过光耦合透镜阵列光耦合到诸如透射型液晶光阀的图像形成装置的像素元件的有源矩阵的高效光源。光源包括单独的初级着色可见辐射发射器（例如单独的磷光体元件）的图案化矩阵，其以适于人眼的方式布置，以将单独的主要着色光整合为单一混合颜色。光耦合透镜阵列基本上收集从每个主要着色光发射器发射的所有光线，并将其聚焦在有源矩阵中的相应一个透明电极上，作为小于电极尺寸的实像。合适的光耦合透镜阵列是梯度折射率透镜阵列，多层，微透镜的二维阵列，功能上类似于带状透镜阵列，或微透镜阵列。可以在图像形成装置中使用扭转向列型液晶单元，以实现高对比度显示。使用光耦合透镜阵列来收集和聚焦来自光源的光线允许聚焦光以最小的散射或发散方式通过入射偏振器，然后通过由不透明像素遮挡的有源矩阵中的相应透明电极互连元件。以这种方式更有效地利用来自光源的更大百分比的光导致形成明亮的高对比度全色图像。

26. 发明授权

US5264880A Method and apparatus for projecting a color image 失效
标题翻译：用于投影彩色图像的方法和装置
公开(公告)号：US5264880A
公开(公告)日：1993-11-23
申请号：US814153
申请日：1991-12-30
申请人： Robert A. Sprague , Richard H. Bruce
发明人： Robert A. Sprague , Richard H. Bruce
IPC分类号： G02B27/10 , G02F1/13 , H04N5/74 , H04N9/31 , G03B21/00
CPC分类号： H04N9/3108 , G02F2001/133623
摘要： A method for achieving a color projection of an image directs light from a source to a dispersive element and disperses the light received by the element into a spectrum of light having different colors at different angles. Each color band of the resulting spectrum is focused, and the dispersed color bands are modulated in color bands corresponding to those received during the focusing onto a modulating element. Finally, the modulated light beams are recombined for projecting onto a projection surface.
摘要翻译：用于实现图像的颜色投影的方法将光从源引导到分散元件，并将由元件接收的光分散成具有不同颜色的不同角度的光的光谱。所得到的光谱的每个色带被聚焦，并且将分散的色带在与聚焦期间接收的色带相对应的色带中调制到调制元件上。最后，调制的光束被重新组合以投影到投影表面上。

27. 发明授权

US5140327A Analog to digital converter utilizing a semiconductor capicitor array 失效
标题翻译：使用半导体电容器阵列的模数转换器
公开(公告)号：US5140327A
公开(公告)日：1992-08-18
申请号：US678495
申请日：1991-04-01
申请人： Richard H. Bruce , Alan G. Lewis , Daniel Senderowicz
发明人： Richard H. Bruce , Alan G. Lewis , Daniel Senderowicz
IPC分类号： H01L27/08 , H03M1/12 , H03M1/46 , H03M1/80
CPC分类号： H03M1/12 , H01L27/0805 , H03M1/468 , H03M1/804
摘要： An improved MOS capacitor array formed on a semiconductor substrate comprises rectangular strips of an active region overlapped by rectangular strips of conductive material. The active region and conductive material are separated by an insulating layer. The strips form an array of capacitors which are more tightly packed than the prior art and which are less sensitive to alignment errors than the prior art.
摘要翻译：形成在半导体衬底上的改进的MOS电容器阵列包括由导电材料的矩形条带重叠的有源区的矩形条。有源区和导电材料被绝缘层隔开。条带形成电容器阵列，其比现有技术更紧密地包装，并且对比对误差比现有技术更不敏感。

28. 发明授权

US09161714B2 Specificity of analyte detection in etalons 有权
标题翻译：标准具中分析物检测的特异性
公开(公告)号：US09161714B2
公开(公告)日：2015-10-20
申请号：US12195942
申请日：2008-08-21
申请人： Joerg Martini , Richard H. Bruce , Francisco E. Torres , Peter Kiesel , Michael I. Recht , Jeffrey N. Roe
发明人： Joerg Martini , Richard H. Bruce , Francisco E. Torres , Peter Kiesel , Michael I. Recht , Jeffrey N. Roe
IPC分类号： A61B5/00 , A61B5/1459 , A61B5/145 , G01N21/33 , G01N21/359
CPC分类号： A61B5/1459 , A61B5/0031 , A61B5/14532 , G01N21/33 , G01N21/359
摘要： A system and method is provided for detecting concentration of an analyte in a fluid. A first container includes (i) an optical cavity detection region, (ii) a reservoir for one or more modifiers of one or more optical properties of the optical cavity detection region, and (iii) a set of one or more bounding regions through which objects in the fluid can transfer into the container. The optical cavity detection region and the reservoir define separate areas of the first container. The movement of the one or more modifiers between the reservoir and the optical cavity detection region is responsive to changes in concentration of the analyte. A second container includes an optical cavity detection region, and a set of one or more bounding regions through which objects in the fluid can transfer into the container. Also provided are optical components for guiding light into the optical cavity detection regions of the first and second containers.
摘要翻译：提供了用于检测流体中分析物的浓度的系统和方法。第一容器包括（i）光腔检测区域，（ii）用于一个或多个光腔检测区域的一个或多个光学特性的修改器的储存器，以及（iii）一组或多个边界区域，流体中的物体可以转移到容器中。光腔检测区域和储存器限定第一容器的分开的区域。储存器和光腔检测区域之间的一个或多个改性剂的运动响应于分析物浓度的变化。第二容器包括光学腔检测区域和一组一个或多个界限区域，流体中的物体可通过该区域传送到容器中。还提供了用于将光引导到第一和第二容器的光学腔检测区域中的光学部件。

29. 发明授权

US08040526B2 Implanting optical cavity structures 有权
标题翻译：植入光腔结构
公开(公告)号：US08040526B2
公开(公告)日：2011-10-18
申请号：US12968115
申请日：2010-12-14
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Richard H. Bruce , Noble M. Johnson
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Richard H. Bruce , Noble M. Johnson
IPC分类号： G01B9/02
CPC分类号： G01N21/03 , A61B5/0075 , A61B5/0084 , A61B5/14532 , A61B5/1459 , G01N21/0303 , G01N21/274 , G01N21/31
摘要： An implantable product includes an optical cavity structure with first and second parts, each of which can operate as an optical cavity. The first part includes a container with at least one opening through which bodily fluid can transfer between the container's interior and exterior when the product is implanted in a body. The second part includes a container that is closed and contains a reference fluid. The implantable product can also include one or both of a light source component and a photosensing component. Photosensed quantities from the first part's output light can be adjusted based on photosensed quantities from the second part's output light. Both parts can have their light interface surfaces aligned so that they both receive input light from a light source component and both provide output light to a photosensing component.
摘要翻译：可植入产品包括具有第一和第二部分的光学腔结构，每个部分可以作为光腔工作。第一部分包括具有至少一个开口的容器，当产品植入体内时，体液可以通过该开口在容器的内部和外部之间转移。第二部分包括封闭的容器并且包含参考流体。可植入产品还可以包括光源组件和感光组件中的一个或两个。可以根据第二部分输出指示灯的光线数量来调整第一部分输出光的照片数量。两个部件可以使它们的光接口表面对准，使得它们都接收来自光源部件的输入光并且都向光敏部件提供输出光。

30. 发明授权

US07914735B2 Use of physical barriers to minimize evaporative heat losses 有权
标题翻译：使用物理障碍来减少蒸发热损失
公开(公告)号：US07914735B2
公开(公告)日：2011-03-29
申请号：US11037666
申请日：2005-01-18
申请人： Francisco E. Torres , Michael Chabinyc , Scott Elrod , Eric Peeters , Gregory B. Anderson , Alan G. Bell , Richard H. Bruce
发明人： Francisco E. Torres , Michael Chabinyc , Scott Elrod , Eric Peeters , Gregory B. Anderson , Alan G. Bell , Richard H. Bruce
IPC分类号： G01N33/00
CPC分类号： G01N25/482 , G01K17/006
摘要： A detection system includes a detection device and an anti-evaporation device. The detection device comprises a region configured to merge at least two small drops and to detect a potential transient signal generated by the merger of the drops. The an anti-evaporation is configured to enclose the region and limit evaporation from the region. A method for detecting a signal includes the following steps: depositing drops of potentially reactive chemical solutions on a detection device within a drop-merging region; placing an anti-evaporation device over the drop-merging region to form a seal around the drop-merging region; merging the drops of potentially reactive chemical solutions; and measuring a signal occurring within the merged solution drops.
摘要翻译：检测系统包括检测装置和防蒸发装置。检测装置包括被配置为合并至少两个小液滴并且检测由液滴的合并产生的潜在瞬态信号的区域。防蒸发被配置为包围该区域并限制该区域的蒸发。一种用于检测信号的方法包括以下步骤：在滴合并区域内的检测装置上沉积潜在的反应性化学溶液滴; 将防蒸发装置放置在熔融合并区域上以形成围绕滴合并区域的密封; 合并潜在的活性化学溶液滴; 并且测量在合并溶液中发生的信号下降。

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