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21. 发明授权

US07121283B2 Satiation devices and methods 有权
公开(公告)号：US07121283B2
公开(公告)日：2006-10-17
申请号：US10794346
申请日：2004-03-04
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
IPC分类号： A61B19/00 , A61F12/04 , A61F5/00
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

22. 发明授权

US06173715B1 Magnetic anatomical marker and method of use 有权
标题翻译：磁解剖标记及使用方法
公开(公告)号：US06173715B1
公开(公告)日：2001-01-16
申请号：US09259222
申请日：1999-03-01
申请人： Mika N. Sinanan , Christopher P. Somogyi , Robert N. Golden , Fred E. Silverstein , Andrei J. Gonzales
发明人： Mika N. Sinanan , Christopher P. Somogyi , Robert N. Golden , Fred E. Silverstein , Andrei J. Gonzales
IPC分类号： A61B1900
CPC分类号： A61B90/39 , A61B2017/00004 , A61B2090/3937 , A61B2090/3954 , A61B2090/3987
摘要： An anatomical marker uses a permanent magnet to indicate a selected location within a patient. The magnet is enclosed within a non-degradable envelope and is coupled to a retention member that is preferably manufactured from a biodegradable material, such as a polyglucuronic acid based material. The retention member may include one or more barbs to retain the anatomical marker in the selected location. An insertion tool, usable with an endoscope, can insert the anatomical marker. A retention magnet is fixedly attached to the insertion tool and holds the anatomical marker in place due to the attractive magnetic forces between the retention magnet and the marker magnet in the non-biodegradable envelope. When the anatomical marker is securely fastened at the selected location in the patient, the forces exerted by the patient's body on the retention member exceed the attractive magnetic forces between the retention magnet and the magnet in the envelope, thus causing the anatomical marker to be released from the insertion tool. The location of the magnet may be subsequently detected using a magnetic detector system.
摘要翻译：解剖标记使用永磁体来指示患者内的选定位置。磁体被封闭在不可降解的外壳内，并且联接到优选由生物可降解材料制成的保持构件，例如聚葡糖醛酸基材料。保持构件可以包括一个或多个倒钩以将解剖标记保持在所选择的位置。可用于内窥镜的插入工具可以插入解剖标记。保持磁体固定地附接到插入工具，并且由于在不可生物降解的外壳中的保持磁体和标记磁体之间的有吸引力的磁力将解剖标记保持在适当位置。当解剖标记被牢固地固定在患者的所选位置时，患者身体施加在保持构件上的力超过保持磁体和外壳中的磁体之间的有吸引力的磁力，从而导致解剖标志物被释放从插入工具。随后可以使用磁检测器系统检测磁体的位置。

23. 发明授权

US5775322A Tracheal tube and methods related thereto 失效
标题翻译：气管及其相关方法
公开(公告)号：US5775322A
公开(公告)日：1998-07-07
申请号：US669763
申请日：1996-06-27
申请人： Fred E. Silverstein , Robert N. Golden , Christopher P. Somogyi
发明人： Fred E. Silverstein , Robert N. Golden , Christopher P. Somogyi
IPC分类号： A61M16/04 , A61M16/00
CPC分类号： A61M16/0488 , A61M16/0411
摘要： There is disclosed a tracheal tube for insertion into the trachea of a patient. The tracheal tube includes a tube portion having a distal end, and a signal source associated with the tube portion at a predefined distance from its distal end. The tracheal tube is inserted into the trachea such that the signal source is immediately posterior to the patient's cricothyroid ligament. Methods related to confirming proper placement of the tracheal tube by detecting the signal source immediately posterior to the patient's cricothyroid ligament are also disclosed.
摘要翻译：公开了一种用于插入患者气管的气管插管。气管管包括具有远端的管部分和与其远端距预定距离的与管部分相关联的信号源。将气管插入气管中，使得信号源紧靠患者甲状腺韧带的后方。还公开了通过检测患者甲状腺韧带后方的信号源来确认气管插管的正确放置的方法。

24. 发明授权

US5013305A Needle safety system and method 失效
标题翻译：针安全系统和方法
公开(公告)号：US5013305A
公开(公告)日：1991-05-07
申请号：US212887
申请日：1988-06-29
申请人： Eric A. Opie , Fred E. Silverstein
发明人： Eric A. Opie , Fred E. Silverstein
IPC分类号： A61M5/31 , A61M5/32 , A61M39/04
CPC分类号： A61M5/3243 , A61M39/04 , A61M5/3202 , A61M5/3273 , A61M2005/3106 , A61M2005/325 , A61M2005/3256 , A61M2039/042 , A61M5/3275
摘要： A device and method for preventing accidental needle sticks. A sleeve having an annular shaft is slidably connected to a needle. A cord is rigidly affixed to the hub of the needle at one end thereof and to a blocking member at the other end thereof is also slidably coupled to the sleeve. After the needle has been used and is being removed from the patient's body, the sleeve is slid along the needle shaft to cover the tip and pulls the blocking member into position over the sharp tip of the needle. This positively covers the sharp tip of a needle with a puncture-proof blocking member to prevent accidental needle sticks. In alternative embodiments, a resilient member is pressed to align a hole through which the needle is projecting with a hole in a puncture-proof member which is covering the sharp tip of the needle to permit the needle protective device to be slid down the shaft of the needle and the needle to be used. A recessed needle assembly to be used in tandem with a needle assembly, is also disclosed. The recessed needle has a protective wall to prevent accidental needle sticks. An over-cover for the entire needle assembly which may be removed once, but when placed on the hub of the needle after having been used, may not be removed a second time from the needle assembly to provide additional protection, is also disclosed.The devices disclosed herein can be used for removing fluid from a patient, transferring fluid to or from and IV system, medicine bottles, vacuum test tubes, etc. A complete system having numerous safety features is described that significantly reduces the risk of accidental needle sticks of all types during each stage that a needle is handled.
摘要翻译：一种用于防止意外针刺的装置和方法。具有环形轴的套筒可滑动地连接到针上。绳索在其一端刚性地固定到针的毂上，而另一端的阻挡构件也可滑动地联接到套筒上。在针被使用并从患者身体移除之后，套筒沿着针轴滑动以覆盖尖端并且将阻挡构件拉到针的尖锐尖端上的位置。这可以肯定地覆盖具有防刺穿阻塞构件的针的锋利尖端，以防止意外的针刺。在替代实施例中，弹性构件被按压以使针在其中突出的孔与防漏构件中的孔对齐，该穿孔防护构件覆盖针的尖端，以允许针保护装置沿着针和针要使用。还公开了与针组件串联使用的凹针组件。凹针具有保护壁，以防止意外的针刺。用于整个针组件的覆盖物可以被去除一次，但是当被使用之后放置在针头的轮毂上时，可能不会再次从针组件移除以提供额外的保护。本文公开的装置可用于从患者中移出流体，将流体输送到或从IV系统，药瓶，真空试管等传输流体。描述了具有许多安全特征的完整系统，其显着降低了意外针刺的风险在处理针的每个阶段中的所有类型。

25. 发明授权

US4997084A Packaging system for disposable endoscope sheaths 失效
标题翻译：一次性内窥镜护套包装系统
公开(公告)号：US4997084A
公开(公告)日：1991-03-05
申请号：US194034
申请日：1988-05-13
申请人： Eric Opie , Fred E. Silverstein
发明人： Eric Opie , Fred E. Silverstein
IPC分类号： G02B23/24 , A61B1/00 , A61B19/02
CPC分类号： A61B1/00144 , A61B1/00142 , A61B50/15 , A61B50/24 , A61B50/30 , A61B50/36 , A61B50/33
摘要： A system for packaging disposable endoscope sheaths so that they do not become contaminated prior to use during shipment, storage and installation on an endoscope. The packaging system also prevents the spread of contamination after use while the sheath is being removed from the endoscope and then discarded. The sheath is shipped in an elongated, flexible bag having a length substantially equal to the length of the insertion tube of the endoscope and a diameter substantially larger than the diameter of the insertion tube. The sheath and bag may be shipped in a sterile tray having a spiral recess containing the sheath, bag and funnel-like container or bag holding the tubing of the air, water, and suction channels. Installation of the sheath on the endoscope is accomplished by inflating the sheath while it is in the bag so that the sheath expands until it contacts the wall of the bag. The insertion tube is then inserted into the sheath, the sheath is deflated and the insertion tube and surrounding sheath are removed from the bag for use. After use, the insertion tube and surrounding sheath are inserted into the bag, and the sheath is inflated until it is restrained from further expansion by the wall of the bag. The insertion tube is then removed from the sheath, the sheath is deflated, and the sheath and surrounding bag are discarded as a unit, the funnel-like proximal segment being used to dispose of the contaminated tubes (air, water, suction, etc.).

26. 发明授权

US4947827A Flexible endoscope 失效
标题翻译：柔性内窥镜
公开(公告)号：US4947827A
公开(公告)日：1990-08-14
申请号：US292473
申请日：1988-12-30
申请人： Eric Opie, deceased , Fred E. Silverstein , David R. Kreft
发明人： Eric Opie, deceased , Fred E. Silverstein , David R. Kreft
IPC分类号： G02B23/24 , A61B1/00 , A61B1/005
CPC分类号： A61B1/00073 , A61B1/0052
摘要： Various methods and mechanical devices for providing manipulation and steering of the bending section of an endoscope having a sheath thereon is disclosed. In one embodiment, the longitudinal center axis of a biopsy type is aligned with the longitudinal center of the insertion tube, both being in common with the instantaneous bending center of the insertion tube. The insertion tube is capable of only right and left movement through steering but is also rotatable with respect to the handle to permit the tip to be positioned in any desired location. In an alternative embodiment, the instantaneous bending center is radially offset from the longitudinal center of the insertion tube. The hinges are positioned in the bending section of the insertion tube for locating the instantaneous center of bending at a desired location in a groove. Four, or in an alternative embodiment, three cables are provided for controlling the movement and steering of the bending section. Because the cables are not symmetrically located with respect to the instantaneous bending center, the mechanical control assembly is designed to take into account the difference between the movements of the respective cable through the full range of motions. In an alternative embodiment, the channel is located radially offset from the instantaneous center of bending and the biopsy tube assembly is made stretchable or compressible to ensure that the biopsy tube end remains aligned with the end of the insertion tube end.
摘要翻译：公开了用于提供具有护套的内窥镜的弯曲部分的操纵和转向的各种方法和机械装置。在一个实施例中，活检类型的纵向中心轴线与插入管的纵向中心对准，两者都与插入管的瞬时弯曲中心相同。插入管能够仅通过转向左右移动，但也可相对于手柄旋转，以允许尖端定位在任何期望的位置。在替代实施例中，瞬时弯曲中心从插入管的纵向中心径向偏移。铰链定位在插入管的弯曲部分中，用于将瞬时的弯曲中心定位在凹槽中的期望位置。四个或替代实施例中，提供三根电缆以控制弯曲部分的移动和转向。由于电缆相对于瞬时弯曲中心不对称地定位，所以机械控制组件被设计成考虑到各个电缆通过全部运动范围的运动之间的差异。在替代实施例中，通道位于径向偏离瞬时弯曲中心的位置，活检管组件被制成可拉伸或可压缩，以确保活检管端部保持与插入管端部的端部对准。

27. 发明授权

US08337567B2 Satiation devices and methods 有权
标题翻译：饱和装置和方法
公开(公告)号：US08337567B2
公开(公告)日：2012-12-25
申请号：US13247377
申请日：2011-09-28
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
IPC分类号： A61F2/04 , A61M5/00
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
摘要翻译：用于在患者中引起体重减轻的装置包括管状假体，该管状假体可从其中假体具有第一直径到扩张位置的可膨胀位置自动扩张，在该位置假体具有第二较大的直径。在用于引起体重减轻的方法中，假体被置于折叠位置并插入患者的胃中。允许假体从折叠位置自身膨胀到扩张位置并与胃的壁接触，其中它引起饱腹感和/或抑制饱腹感调节因子如Ghrelin的调节。

28. 发明申请

US20120143029A1 Systems and methods for guiding a medical instrument 有权
标题翻译：用于引导医疗器械的系统和方法
公开(公告)号：US20120143029A1
公开(公告)日：2012-06-07
申请号：US13336919
申请日：2011-12-23
申请人： Fred E. Silverstein , Robert N. Golden
发明人： Fred E. Silverstein , Robert N. Golden
IPC分类号： A61B5/042 , A61B5/05
CPC分类号： A61B5/062 , A61B5/042 , A61B5/743 , A61B5/7475 , A61B8/0833 , A61B8/0841 , A61B8/0891 , A61B8/4472 , A61B8/463 , A61B34/20 , A61B90/37 , A61B90/98 , A61B2034/2051 , A61B2090/374 , A61B2090/378 , A61B2090/3954
摘要： A guidance system for assisting with the insertion of a needle into a patient body is disclosed. The guidance system utilizes ultrasound imaging or other suitable imaging technology. In one embodiment, the guidance system comprises an imaging device including a probe for producing an image of an internal body portion target, such as a vessel. One or more sensors are included with the probe. The sensors sense a detectable characteristic related to the needle, such as a magnetic field of a magnet included with the needle. The system includes a processor that uses data relating to the sensed characteristic to determine a 3-D position of the needle. The system includes a display for depicting the position of the needle. In other embodiments, a guidance system for guiding rigid or other medical instruments is disclosed, together with various example implementations thereof.
摘要翻译：公开了一种用于辅助将针插入患者体内的引导系统。引导系统利用超声成像或其他合适的成像技术。在一个实施例中，引导系统包括成像装置，其包括用于产生诸如血管的内部身体部分目标的图像的探针。探头附带一个或多个传感器。传感器检测与针相关的可检测特性，例如包括在针中的磁体的磁场。该系统包括使用与感测特征有关的数据来确定针的3-D位置的处理器。该系统包括用于描绘针的位置的显示器。在其他实施例中，公开了用于引导刚性或其它医疗器械的引导系统及其各种示例实施方式。

29. 发明申请

US20120016287A1 SATIATION DEVICES AND METHODS 有权
标题翻译：舒适装置及方法
公开(公告)号：US20120016287A1
公开(公告)日：2012-01-19
申请号：US13247400
申请日：2011-09-28
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
摘要翻译：用于在患者中引起体重减轻的装置包括管状假体，该管状假体可从其中假体具有第一直径到扩张位置的可膨胀位置自动扩张，在该位置假体具有第二较大的直径。在用于引起体重减轻的方法中，假体被置于折叠位置并插入患者的胃中。允许假体从折叠位置自身膨胀到扩张位置并与胃的壁接触，其中它引起饱腹感和/或抑制饱腹感调节因子如Ghrelin的调节。

30. 发明授权

US06675809B2 Satiation devices and methods 有权
标题翻译：饱和装置和方法
公开(公告)号：US06675809B2
公开(公告)日：2004-01-13
申请号：US09940110
申请日：2001-08-27
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
IPC分类号： A61B1900
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
摘要翻译：用于在患者中引起体重减轻的装置包括管状假体，该管状假体可从其中假体具有第一直径到扩张位置的可膨胀位置自动扩张，在该位置假体具有第二较大的直径。在用于引起体重减轻的方法中，假体被置于折叠位置并插入患者的胃中。允许假体从折叠位置自身膨胀到扩张位置并与胃的壁接触，其中它引起饱腹感和/或抑制饱腹感调节因子如Ghrelin的调节。

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