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21. 发明授权

US09597042B2 Perfusion imaging 有权
公开(公告)号：US09597042B2
公开(公告)日：2017-03-21
申请号：US13266556
申请日：2010-04-09
申请人： Roland Proksa , Michael Grass
发明人： Roland Proksa , Michael Grass
IPC分类号： G06K9/00 , A61B6/03 , A61B6/00
CPC分类号： A61B6/032 , A61B6/481 , A61B6/482 , A61B6/486 , A61B6/504 , A61B6/507
摘要： A method is disclosed that includes decomposing, with a decomposer, agent-based time series projection data for an object or a subject into at least an agent based component. A projection data decomposer includes a time series decomposer that determines agent-based projection data based on agent-based time series projection data based on at least two energy dependent components. A computer readable storage medium containing instructions which, when executed by a computer, cause the computer to perform the act of determining an agent-based component of agent-based time series projection data utilizing at least two components of the agent-based time series projection is provided.

22. 发明申请

US20160009898A1 ISONONYL ESTERS BASED ON FATTY ACIDS OR FATTY ACID MIXTURES FROM TALL OIL OR LINSEED OIL 审中-公开
标题翻译：基于脂肪酸或脂肪酸混合物的来自石油或林油的异烟肼
公开(公告)号：US20160009898A1
公开(公告)日：2016-01-14
申请号：US14773649
申请日：2014-02-14
申请人： Benjamin Woldt , Michael Grass , Andreas Gevers
发明人： Benjamin Woldt , Michael Grass , Andreas Gevers
IPC分类号： C08K5/1515 , C07D303/16 , C07D407/06
CPC分类号： C08K5/1515 , C07D303/16 , C07D407/06 , C08K5/101 , C08L27/06
摘要： The invention relates to an isononyl ester or isononyl ester mixture of an epoxidized fatty acid or an epoxidized fatty acid mixture, the fatty acid or fatty acid mixture being extracted from tall oil or linseed oil and the average number of epoxide groups per fatty acid being greater than 1.00.
摘要翻译：本发明涉及环氧化脂肪酸或环氧化脂肪酸混合物的异壬酯或异壬基酯混合物，脂肪酸或脂肪酸混合物由妥尔油或亚麻子油提取，每个脂肪酸的平均环氧基数大于超过1.00。

23. 发明授权

US09087404B2 Reconstruction for cone-beam computed tomography imaging with off-center flat panel detector 有权
标题翻译：用偏心平板检测器进行锥束计算机断层扫描成像的重建
公开(公告)号：US09087404B2
公开(公告)日：2015-07-21
申请号：US13697445
申请日：2011-04-25
申请人： Eberhard S. Hansis , Dirk Schaefer , Michael Grass
发明人： Eberhard S. Hansis , Dirk Schaefer , Michael Grass
IPC分类号： G01N23/04 , G06T1/00 , G06T11/00
CPC分类号： G06T11/008 , G06T11/006 , G06T2211/432
摘要： Computed tomography (CT) reconstruction includes reconstructing an axially extended reconstructed image from a measured cone beam x-ray projection data set (Pm), optionally having an off-center geometry. The reconstructing is performed for an extended volume (eFOV) comprising a reconstructable volume (rFOV) of the measured cone beam x ray data set that is extended along the axial direction. The projection data set may be weighted in the volume domain. Iterative reconstruction may be used, including initializing a constant volume and performing one or more iterations employing a first iterative update followed by one or more iterations employing a second, different iterative update. Alternatively, backprojection filtration (BPF) reconstruction may be used, including transforming the projection data set to a new geometry including finite differences between neighboring projection views and performing BPF using Hilbert filtering along a plurality of different directions and averaging the resultant reconstructed images to generate the final reconstructed image.
摘要翻译：计算机断层摄影（CT）重建包括从测量的锥形束X射线投影数据集（Pm）重建轴向延伸的重建图像，可选地具有偏心几何。对包括沿轴向延伸的测量的锥形束x射线数据集的可重建体积（rFOV）的扩展体积（eFOV）进行重建。投影数据集可以在体积域中加权。可以使用迭代重建，包括初始化恒定体积并且使用第一迭代更新执行一个或多个迭代，随后使用第二，不同迭代更新的一个或多个迭代。或者，可以使用反投影过滤（BPF）重建，包括将投影数据集变换为包括相邻投影视图之间的有限差异的新几何，并且使用沿着多个不同方向的希尔伯特滤波来执行BPF，并平均所得到的重建图像以产生最终重建图像。

24. 发明授权

US09002089B2 Image data registration for dynamic perfusion CT 有权
标题翻译：用于动态灌注CT的图像数据注册
公开(公告)号：US09002089B2
公开(公告)日：2015-04-07
申请号：US13643167
申请日：2011-04-12
申请人： Michael Grass , Alfonso Agatino Isola
发明人： Michael Grass , Alfonso Agatino Isola
IPC分类号： G06K9/00 , G06T7/00 , A61B6/00
CPC分类号： G06T7/0026 , A61B6/507 , G06T7/32 , G06T2207/10076 , G06T2207/30104
摘要： A method of registering a 4D contrast enhanced image data set, wherein the 4D contrast enhanced image data set includes image data of the same volume of interest acquired at different timeframes with changing contrast enhancement, the volume of interest includes moving structure, and the different timeframes correspond to a predetermined motion phase of interest in different motion cycles of the moving structure, the method, comprising: registering image data corresponding to a plurality of the different timeframes with reference image from one of the timeframes.
摘要翻译：一种注册4D对比度增强图像数据集的方法，其中所述4D对比度增强图像数据集包括在改变对比度增强的不同时间帧处获取的相同感兴趣体积的图像数据，所述感兴趣的体积包括移动结构和不同的时间帧对应于移动结构的不同运动周期中的感兴趣的预定运动相位，该方法包括：将与多个不同时间帧对应的图像数据与来自其中一个时间帧的参考图像进行对应。

25. 发明申请

US20150018576A1 METHOD AND DEVICE FOR THE HYDROFORMYLATION OF ISOBUTENE AND FOR THE SEPARATION OF THE PRODUCT MIXTURE 有权
标题翻译：用于分离产品混合物的方法和装置
公开(公告)号：US20150018576A1
公开(公告)日：2015-01-15
申请号：US14380647
申请日：2013-02-11
申请人： Goetz Baumgarten , Michael Grass , Alfred Kaizik , Markus Winterberg , Hans-Gerd Lueken , Bart Hamers , Markus Priske , Dirk Fridag , Robert Franke , Dieter Hess
发明人： Goetz Baumgarten , Michael Grass , Alfred Kaizik , Markus Winterberg , Hans-Gerd Lueken , Bart Hamers , Markus Priske , Dirk Fridag , Robert Franke , Dieter Hess
IPC分类号： C07C51/43 , C07C51/235 , C07C45/78 , C07C45/50
CPC分类号： C07C51/43 , B01D61/027 , C07C45/50 , C07C45/505 , C07C45/786 , C07C45/82 , C07C51/235 , C07C47/02
摘要： The invention relates to a method for producing a product mixture (2) by means of the technical hydroformylation of a hydrocarbon stream (1) that contains isobutene, and for separating the product mixture (2) that is obtained, as well as to a device for the claimed method and to the use of a claimed device. The problem addressed thereby is that of providing a method and an associated device that allow the amount of high-boiling substances in the product mixture (2) to be kept as low as possible and thus the yield of the reaction to be increased. The problem is solved by the use of a nano-filtration device (M) for separating the catalyst from the product mixture (2), said device having especially high permeability to 3-methylbutanoic acid.
摘要翻译：本发明涉及一种通过含有异丁烯的烃流（1）的技术加氢甲酰化以及用于分离获得的产物混合物（2）以及制备产物混合物（2）的方法，用于所要求保护的方法和所要求保护的装置的使用。由此提出的问题是提供一种方法和相关联的装置，其允许将产物混合物（2）中的高沸点物质的量保持尽可能低，从而提高反应的产率。通过使用纳米过滤装置（M）从产物混合物（2）中分离催化剂来解决该问题，所述装置对3-甲基丁酸具有特别高的渗透性。

26. 发明申请

US20140088226A1 DIANHYDROHEXITOL DIESTERS OF 2-ETHYLHEPTANOIC ACID 审中-公开
标题翻译：二乙二醇酸的二氢呋喃糖醇
公开(公告)号：US20140088226A1
公开(公告)日：2014-03-27
申请号：US14119994
申请日：2012-04-26
申请人： Andreas Gevers , Hinnerk Becker , Michael Grass , Markus Winterberg , Dietrich Maschmeyer , Christian Boeing
发明人： Andreas Gevers , Hinnerk Becker , Michael Grass , Markus Winterberg , Dietrich Maschmeyer , Christian Boeing
IPC分类号： C08K5/1535
CPC分类号： C08K5/1535 , C07D493/04 , C08K5/0016 , C08L27/06
摘要： Dianhydrohexitol diesters of 2-ethylheptanoic acid
摘要翻译： 2-乙基庚酸的二氢己糖二酯

27. 发明申请

US20130317153A1 DIISONONYL TEREPHTHALATE (DINT) AS SOFTENER FOR THERMOPLASTIC APPLICATIONS 审中-公开
标题翻译：作为热塑性应用的辅助剂的二硝基苯乙烯（DITONONYL TEREPHTHALATE（DINT）
公开(公告)号：US20130317153A1
公开(公告)日：2013-11-28
申请号：US13989422
申请日：2011-10-31
申请人： Michael Grass , Hinnerk Gordon Becker
发明人： Michael Grass , Hinnerk Gordon Becker
IPC分类号： C08K5/12 , C08K3/26
CPC分类号： C08K3/26 , C08K5/12
摘要： The present invention relates to the use of diisononyl terephthalate (DINT) as plasticizer for enhancing the low-temperature flexibilization and/or for enhancing the permanence in polymer compositions for thermoplastic applications.
摘要翻译：本发明涉及对苯二甲酸二异壬酯（DINT）作为增塑剂用于增强低温柔韧性和/或提高热塑性应用的聚合物组合物的耐久性的用途。

28. 发明授权

US08586784B2 Method for continuous catalytic hydrogenation 有权
标题翻译：连续催化氢化方法
公开(公告)号：US08586784B2
公开(公告)日：2013-11-19
申请号：US11320409
申请日：2005-12-29
申请人： Michael Grass , Burkhard Reeken , Axel Tuchlenski , Alfred Kaizik
发明人： Michael Grass , Burkhard Reeken , Axel Tuchlenski , Alfred Kaizik
IPC分类号： C07C61/00
CPC分类号： C07C67/303 , Y02P20/582 , C07C69/75
摘要： The invention relates to the preparation of alicyclic carboxylic acids or their derivatives by selective hydrogenation of the corresponding aromatic carboxylic acid (derivatives) in at least two series-connected reactors, at least one reactor being operated in loop operating mode. The catalyst volumes in the method are set in such a manner that the catalyst volume required, based on the conversion rate, is as low as possible.
摘要翻译：本发明涉及通过在至少两个串联连接的反应器中选择性氢化相应的芳族羧酸（衍生物）来制备脂环族羧酸或其衍生物，至少一个反应器以循环操作模式操作。该方法中的催化剂体积设定为使得基于转化率所需的催化剂体积尽可能低。

29. 发明申请

US20130279783A1 COMPUTED TOMOGRAPHY SYSTEM AND METHOD FOR TRACKING A BOLUS 有权
标题翻译：计算机图像系统和追踪玻璃的方法
公开(公告)号：US20130279783A1
公开(公告)日：2013-10-24
申请号：US13977042
申请日：2012-01-04
申请人： Holger Schmitt , Michael Grass
发明人： Holger Schmitt , Michael Grass
IPC分类号： G06T11/00
CPC分类号： G06T11/008 , A61B6/032 , A61B6/469 , A61B6/481 , A61B6/488 , A61B6/504
摘要： The present invention relates to a computed tomography system (10) and a corresponding method which enable tracking of a contrast material bolus and which involve a reduced radiation dose. The proposed computed tomography system (10) comprises an acquisition unit including an X-ray source (18) and an X-ray detector (30) for acquiring projection data sets (42, 44, 46), a reconstruction unit (41) for reconstructing a planning image (48) from a first projection data set (42), an identification unit (52) for identifying a region of interest (40) in the planning image (48), a selection unit (54) for selecting a projection angle (60) through the region of interest (40), a calculator (62) for calculating a target projection value (64) for a projection of said region of interest (40) with the selected projection angle (60), a control unit (32) for controlling said acquisition unit to acquire a second, reduced projection data set (44) including projection data from projections of said region of interest (40) with the selected projection angle (60), and a comparator (68) for comparing projection values of the second projection data set (44) with the target projection value (64), wherein the control unit (32) is adapted to control the acquisition unit to initiate the acquisition of a third projection data set (46) based on the comparison result (70) and to reconstruct a diagnostic image (50) from the third projection data set (46).
摘要翻译：本发明涉及计算机断层摄影系统（10）和相应的方法，其能够跟踪造影剂推注并涉及降低的辐射剂量。所提出的计算机断层摄影系统（10）包括：采集单元，包括用于获取投影数据组（42,44,46）的X射线源（18）和X射线检测器（30）;重建单元（41），用于从第一投影数据集（42）重建规划图像（48）;识别单元（52），用于识别所述规划图像（48）中的感兴趣区域（40）;选择单元（54），用于选择投影通过感兴趣区域（40）的角度（60）;计算器（62），用于计算用于所选择的投影角度（60）的所述感兴趣区域（40）的投影的目标投影值（64）;控制单元（32），用于控制所述获取单元以选择的投影角度（60）获取包括来自所述感兴趣区域（40）的投影的投影数据的第二缩小投影数据集（44），以及比较器第二投影数据集（44）的投影值与目标投影值（64），w 这里，控制单元（32）适于控制采集单元基于比较结果（70）开始获取第三投影数据集（46），并且从第三投影数据集重建诊断图像（50）（46）。

30. 发明申请

US20130261439A1 INTERVENTIONAL APPARATUS ACTIVATED COMPUTED TOMOGRAPHY (CT) 有权
标题翻译：传统装置激活计算机断层扫描（CT）
公开(公告)号：US20130261439A1
公开(公告)日：2013-10-03
申请号：US13992421
申请日：2011-11-25
申请人： Holger Schmitt , Michael Grass
发明人： Holger Schmitt , Michael Grass
IPC分类号： A61B6/03 , A61B5/055 , A61B8/00 , A61B5/00 , A61B6/00 , A61M25/01 , A61B8/08
CPC分类号： A61B6/032 , A61B5/0084 , A61B5/055 , A61B5/742 , A61B6/037 , A61B6/12 , A61B6/4423 , A61B6/463 , A61B6/542 , A61B6/547 , A61B8/0841 , A61B8/463 , A61B34/20 , A61B90/98 , A61B2034/2055 , A61B2034/2059 , A61B2034/2065 , A61B2090/3945 , A61M25/0108 , A61M25/0113 , A61M25/0127 , A61M2025/0008 , A61M2025/0166
摘要： A system (100) includes an interventional apparatus (102) and an imaging scanner (101). The interventional apparatus includes a interventional instrument (204) configured to perform an image-guided interventional procedure for a patient. The interventional apparatus includes a position detector (122) that detects a position of the interventional instrument within a region of the patient at which the image-guided interventional procedure is performed from outside of the region of interest and generates a signal indicative of the detected position. The imaging scanner includes a controller (114) that activates the imaging scanner to scan the region of interest and the interventional instrument therein for one or more data acquisition cycles based on the movement signal.
摘要翻译：系统（100）包括介入装置（102）和成像扫描器（101）。介入装置包括被配置为对患者执行图像引导介入手术的介入器械（204）。介入装置包括位置检测器（122），其检测介入器械在患者的区域内的位置，在该区域内从感兴趣区域外部执行图像引导的介入程序，并产生指示检测位置的信号。成像扫描器包括控制器（114），其基于移动信号激活成像扫描器以扫描感兴趣区域和其中的介入仪器用于一个或多个数据采集周期。

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