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21. 发明申请

US20050122512A1 Optical wavelength standard and optical wavelength calibration system and method 失效
标题翻译：光波长标准和光波长校准系统及方法
公开(公告)号：US20050122512A1
公开(公告)日：2005-06-09
申请号：US10729508
申请日：2003-12-05
申请人： Annette Grot , Thomas Mikes
发明人： Annette Grot , Thomas Mikes
IPC分类号： G01J3/10 , G01J3/28 , G01N21/27 , G01N21/47 , G01N21/55 , G01J1/10
CPC分类号： G01N21/278 , G01J3/10 , G01J2003/2866 , G01N21/4788 , G01N21/554 , G01N2201/08
摘要： The optical wavelength standard comprises a diffraction grating having a diffractive surface, an input arrangement and an output optical arrangement. The input optical arrangement is located to illuminate the diffractive surface of the diffraction grating with incident light at an angle of incidence at which absorption of the incident light at a resonance wavelength generates surface plasmons. The output optical arrangement is located to receive the incident light specularly reflected from the diffractive surface of the diffraction grating as reflected light. The reflected light includes an absorption line at the resonance wavelength. The absorption line provides the wavelength reference. The resonance wavelength is defined by the angle of incidence and the physical characteristics of the diffraction grating. A desired resonance wavelength can be obtained by appropriately defining the angle of incidence and the physical characteristics of the diffraction grating. Moreover, the resonance wavelength can be changed by changing either or both of the angle of incidence and the diffraction grating.
摘要翻译：光学波长标准包括具有衍射面的衍射光栅，输入布置和输出光学布置。输入光学布置被定位成以入射角以入射光照射衍射光栅的衍射表面，入射光在共振波长处的入射光的吸收产生表面等离子体激元。输出光学布置被定位为接收从衍射光栅的衍射表面镜面反射的入射光作为反射光。反射光包括在共振波长处的吸收线。吸收线提供波长参考。谐振波长由入射角和衍射光栅的物理特性定义。可以通过适当地限定入射角和衍射光栅的物理特性来获得期望的共振波长。此外，可以通过改变入射角和衍射光栅中的一个或两个来改变谐振波长。

22. 发明申请

US20050025428A1 Optical alignment of optical waveguides 失效
标题翻译：光波导的光学对准
公开(公告)号：US20050025428A1
公开(公告)日：2005-02-03
申请号：US10628171
申请日：2003-07-28
申请人： Annette Grot , Kenneth Wildnauer
发明人： Annette Grot , Kenneth Wildnauer
IPC分类号： G02B6/26
CPC分类号： G02B6/26
摘要： The optical WG device comprises two optical WGs and an optical coupler extending between the adjacent ends of the WGs. The optical coupler comprises material that includes a waveguide region. The waveguide region has a shape defined by overlapping cones of light emitted from the ends of the optical waveguides. In the optical alignment method, first and second optical waveguides are axially aligned, leaving a gap between their adjacent ends. The gap is filled with material having a refractive index capable of being increased by exposing the material to light. The material is exposed to conical beams of light emitted from the adjacent ends of the waveguides. Exposing the material increases the refractive index of the material in a region in which the beams of light overlap. The resulting refractive index difference prevents light from diverging as it propagating across the gap between adjacent ends of the optical waveguides.
摘要翻译：光学WG器件包括两个光学WG和在WG的相邻端之间延伸的光耦合器。光耦合器包括包括波导区域的材料。波导区域具有由从光波导的端部发射的光的重叠锥形限定的形状。在光学对准方法中，第一和第二光波导轴向对准，在其相邻端之间留有间隙。该间隙填充有通过将材料暴露于光而能够增加折射率的材料。该材料暴露于从波导的相邻端发射的锥形光束。暴露材料增加了光束重叠的区域中材料的折射率。所产生的折射率差阻止光在其穿过光波导的相邻端之间的间隙传播时发散。

23. 发明授权

US08906670B2 Zero-mode waveguides with non-reflecting walls 有权
标题翻译：具有非反射壁的零模式波导
公开(公告)号：US08906670B2
公开(公告)日：2014-12-09
申请号：US12877764
申请日：2010-09-08
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
IPC分类号： C12M1/34 , G01N21/64 , G02B6/10 , G01N21/77
CPC分类号： G02B6/107 , C23F1/00 , C23F17/00 , C25D11/022 , C25D11/04 , G01N21/6452 , G01N21/7743 , G02B6/10 , G02B6/136
摘要： The application relates to improved optical containment structures, methods of manufacture and use, and systems for employing same. The optical containment structures generally comprise zero-mode waveguide structures having non-reflective walls. The non-reflective walls allow the preparation of optical containment regions in which the optical containment dimensions can be decoupled from the solution containment dimensions. The application also relates to methods for producing islands of functionality within nanoscale apertures.
摘要翻译：本申请涉及改进的光学容纳结构，制造和使用方法以及使用它们的系统。光学容纳结构通常包括具有非反射壁的零模式波导结构。非反射壁允许制备光学容纳区域，其中光学容纳尺寸可以与溶液容纳尺寸分离。该应用还涉及在纳米尺度孔内产生功能岛的方法。

24. 发明授权

US08367159B2 Methods for producing ZMWs with islands of functionality 有权
标题翻译：用于生产具有功能岛的ZMW的方法
公开(公告)号：US08367159B2
公开(公告)日：2013-02-05
申请号：US12962249
申请日：2010-12-07
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
IPC分类号： G02B6/122 , G02B6/28
CPC分类号： G02B6/122 , G01N21/6428
摘要： The application relates to methods for producing islands of functionality within nanoscale apertures. Islands of functionality can be produced by growing an aperture constriction layer from the walls, functionalizing the exposed base of the aperture, then removing the aperture constriction layer. The aperture constriction layer can be produced, for example, by anodically growing an oxide layer onto a cladding through which the aperture extends. The islands of functionality can be used to bind a single molecule of interest, such as an enzyme within the nanoscale aperture.
摘要翻译：该应用涉及在纳米尺度孔内产生功能岛的方法。功能岛可以通过从壁上生长孔径收缩层来实现，使孔的暴露的基底功能化，然后去除孔径收缩层。孔径收缩层可以例如通过将氧化物层阳极生长到孔径延伸穿过的包层上来产生。功能岛可以用来结合单一的目标分子，例如在纳米尺度孔内的酶。

25. 发明申请

US20130023039A1 HIGH MULTIPLEX ARRAYS AND SYSTEMS 审中-公开
标题翻译：高多重阵列和系统
公开(公告)号：US20130023039A1
公开(公告)日：2013-01-24
申请号：US13552497
申请日：2012-07-18
申请人： Denis Zaccarin , Paul Lundquist , Peiqian Zhao , Cheng Frank Zhong , Stephen Turner , Yanqiao Huang , Pezhman Monadgemi , Ravi Saxena , Annette Grot , Aaron Rulison
发明人： Denis Zaccarin , Paul Lundquist , Peiqian Zhao , Cheng Frank Zhong , Stephen Turner , Yanqiao Huang , Pezhman Monadgemi , Ravi Saxena , Annette Grot , Aaron Rulison
IPC分类号： C12M1/34
CPC分类号： G01N21/6452 , B05D1/005 , C23C16/50 , G01N21/253 , G02B6/12002 , G02B6/131 , G02B6/132 , G02B6/136 , G02B2006/12035 , G02B2006/12061 , G02B2006/12104 , G02B2006/12164 , G02B2006/12197
摘要： Apparatus, systems and methods for use in analyzing discrete reactions at ultra high multiplex with reduced optical noise, and increased system flexibility. Apparatus include substrates having integrated optical components that increase multiplex capability by one or more of increasing density of reaction regions, improving transmission of light to or collection of light from discrete reactions regions. Integrated optical components include reflective optical elements which re-direct illumination light and light emitted from the discrete regions to more efficiently collect emitted light. Particularly preferred applications include single molecule reaction analysis, such as polymerase mediated template dependent nucleic acid synthesis and sequence determination.
摘要翻译：用于分析离散反应的设备，系统和方法，以超高的多重复用，降低光学噪声，提高系统灵活性。装置包括具有集成光学部件的衬底，其通过一个或多个增加密度的反应区域增加多重能力，改善光从离散反应区域发射或收集光。集成光学部件包括反射光学元件，其重新引导照明光和从离散区域发射的光以更有效地收集发射的光。特别优选的应用包括单分子反应分析，例如聚合酶介导的模板依赖性核酸合成和序列测定。

26. 发明授权

US08330721B2 Optical navigation device with phase grating for beam steering 有权
标题翻译：具有光束转向相位光栅的光学导航装置
公开(公告)号：US08330721B2
公开(公告)日：2012-12-11
申请号：US12388776
申请日：2009-02-19
申请人： Annette Grot
发明人： Annette Grot
IPC分类号： G09G5/08
CPC分类号： G06F3/0317
摘要： An optical navigation device with a phase grating for beam steering. The optical navigation device includes a light source, and image sensor, and a beam steering element. The light source directs a light beam toward a navigation surface. The image sensor receives light along an imaging path and generates a navigation image of the navigation surface from the light received along the imaging path. The beam steering element is disposed between the navigation surface and the image sensor. The beam steering element receives reflected light from the navigation surface along a specular reflection path. The beam steering element directs a first portion of the reflected light along the imaging path toward the image sensor. The beam steering element directs a second portion of the reflected light along a beam steering path away from the imaging path.
摘要翻译：一种具有用于光束转向的相位光栅的光学导航装置。光学导航装置包括光源，图像传感器和光束操纵元件。光源将光束引向导航表面。图像传感器沿着成像路径接收光，并从沿着成像路径接收的光生成导航面的导航图像。光束操纵元件设置在导航表面和图像传感器之间。光束操纵元件沿着镜面反射路径接收来自导航表面的反射光。光束操纵元件沿着成像路径将反射光的第一部分引向图像传感器。光束操纵元件将反射光的第二部分沿着光束转向路径引导远离成像路径。

27. 发明申请

US20110117637A1 ZERO-MODE WAVEGUIDES WITH NON-REFLECTING WALLS 有权
标题翻译：具有非反射壁的零模式波形
公开(公告)号：US20110117637A1
公开(公告)日：2011-05-19
申请号：US12877764
申请日：2010-09-08
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
IPC分类号： C12M1/34 , G02B6/12 , H01J40/00 , B05D5/06
CPC分类号： G02B6/107 , C23F1/00 , C23F17/00 , C25D11/022 , C25D11/04 , G01N21/6452 , G01N21/7743 , G02B6/10 , G02B6/136
摘要： The application relates to improved optical containment structures, methods of manufacture and use, and systems for employing same. The optical containment structures generally comprise zero-mode waveguide structures having non-reflective walls. The non-reflective walls allow the preparation of optical containment regions in which the optical containment dimensions can be decoupled from the solution containment dimensions. The application also relates to methods for producing islands of functionality within nanoscale apertures.
摘要翻译：本申请涉及改进的光学容纳结构，制造和使用方法以及使用它们的系统。光学容纳结构通常包括具有非反射壁的零模式波导结构。非反射壁允许制备光学容纳区域，其中光学容纳尺寸可以与溶液容纳尺寸分离。该应用还涉及在纳米尺度孔内产生功能岛的方法。

28. 发明申请

US20070147460A1 VCSEL WITH INTEGRATED LENS 有权
标题翻译： VCSEL与集成镜头
公开(公告)号：US20070147460A1
公开(公告)日：2007-06-28
申请号：US11684375
申请日：2007-03-09
申请人： Tak Wang , Frank Hu , Annette Grot
发明人： Tak Wang , Frank Hu , Annette Grot
IPC分类号： H01S3/04 , H01S3/08
CPC分类号： H01S5/423 , H01S5/18388
摘要： A wafer-level device fabrication process forms standing structures around emitting areas of multiple VCSELs. The standing structures can be shaped to hold ball lenses or other optical elements for respective VCSELs or can include platforms on which optical elements are formed. Ball lenses that are attached to the standing structures either during chip-level or wafer-level processes fit into the standing structures and are automatically aligned. Wafer level fabrication of optical elements can align the optical elements with accuracies associated with photolithographic processes. The optical elements can be formed using a molding or replication process, a printing method, or surface tension during a reflow of lithographically formed regions.
摘要翻译：晶片级器件制造工艺在多个VCSEL的发射区域周围形成站立结构。立体结构可以被成形为保持用于相应VCSEL的球透镜或其它光学元件，或者可以包括其上形成有光学元件的平台。在芯片级或晶片级工艺期间连接到立式结构的球透镜适合于立式结构并自动对准。光学元件的晶片级制造可以将光学元件与光刻工艺相关的精度对准。可以在光刻形成区域的回流期间使用模制或复制工艺，印刷方法或表面张力来形成光学元件。

29. 发明申请

US20060029347A1 PHOTONIC CRYSTAL RESONATOR APPARATUS WITH IMPROVED OUT OF PLANE COUPLING 有权
标题翻译：具有改进的平面耦合的光子晶体谐振器装置
公开(公告)号：US20060029347A1
公开(公告)日：2006-02-09
申请号：US10910216
申请日：2004-08-03
申请人： Mihail Sigalas , Annette Grot , Laura Mirkarimi
发明人： Mihail Sigalas , Annette Grot , Laura Mirkarimi
IPC分类号： G02B6/00 , G02B6/10 , G02B6/12
CPC分类号： B82Y20/00 , G02B6/1225 , G02B2006/12109
摘要： A two-dimensional photonic crystal resonator apparatus in which the power of light coupled out of the apparatus in one direction is greater than the power of light coupled out of the apparatus in the opposite direction The apparatus has a photonic crystal slab waveguide structure having a waveguide and a resonator in the vicinity of the waveguide such that light propagated through the waveguide is extracted from the waveguide through the resonator and is coupled out of the plane of the apparatus. The apparatus has upper and lower cladding layers on the photonic crystal slab waveguide structure having different indices of refraction, and the power of light coupled out of the apparatus in the direction of the cladding layer having the higher index of refraction is greater than the power of the light coupled out of the apparatus in the direction of the cladding layer having the lower index of refraction.
摘要翻译：一种二维光子晶体谐振器装置，其中在一个方向上耦合出设备的光的功率大于在相反方向上耦合到设备外的光的功率。该装置具有光子晶体平板波导结构，其具有波导以及在波导附近的谐振器，使得通过波导传播的光从波导通过谐振器提取出来并被耦合到设备的平面之外。该装置在具有不同折射率的光子晶体平板波导结构上具有上包层和下包层，并且在具有较高折射率的包层的方向上耦合到装置外的光的功率大于在具有较低折射率的包层的方向上耦合出装置的光。

30. 发明授权

US06811328B2 Optical fiber splicing using surface tension 失效
标题翻译：光纤拼接使用表面张力
公开(公告)号：US06811328B2
公开(公告)日：2004-11-02
申请号：US10156215
申请日：2002-05-28
申请人： Rene P. Helbing , Annette Grot , Fred Sugihwo
发明人： Rene P. Helbing , Annette Grot , Fred Sugihwo
IPC分类号： G02B6255
CPC分类号： G02B6/3801
摘要： Optical systems that include optical fiber splices are provided. Such an optical system includes first and second optical fibers, each of which has an end surface and a side surface adjacent to the end surface. An adhesive joins the end surface of the first optical fiber to the end surface of the second optical fiber. Additionally, at least a portion of the end surface of the first optical fiber exhibits a wettability for the adhesive that is higher than a wettability for the adhesive exhibited by at least a portion of the side surface of the first optical fiber. Methods and other systems also are provided.
摘要翻译：提供包括光纤接头的光学系统。这种光学系统包括第一和第二光纤，每个光纤具有端表面和与端表面相邻的侧表面。粘合剂将第一光纤的端面连接到第二光纤的端面。此外，第一光纤的端面的至少一部分表现出比第一光纤的侧表面的至少一部分表现出的粘合剂的润湿性高的粘合剂的润湿性。还提供了方法和其它系统。

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