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21. 发明申请

US20060052616A1 Phosphinic acid analogs of glutamate 失效
标题翻译：谷氨酸的次膦酸类似物
公开(公告)号：US20060052616A1
公开(公告)日：2006-03-09
申请号：US10534528
申请日：2003-11-14
申请人： Fridtjof Schroder , Andreas Natsch
发明人： Fridtjof Schroder , Andreas Natsch
IPC分类号： A61K8/55 , C07F9/22 , C07F9/547
CPC分类号： C07F9/306 , C07F9/301 , C07F9/302
摘要： Inhibitors of axillary malodour having the formula wherein R has the same meaning as given in the specification.
摘要翻译：具有配方的腋窝恶臭抑制剂

22. 发明申请

US20050101678A1 Antibacterial composition 审中-公开
标题翻译：抗菌组成
公开(公告)号：US20050101678A1
公开(公告)日：2005-05-12
申请号：US10657345
申请日：2003-09-08
申请人： Andreas Natsch
发明人： Andreas Natsch
IPC分类号： A01N31/06 , A61K8/34 , A61K31/045 , A61K31/075 , A61Q15/00 , A61Q17/00 , A61Q19/00
CPC分类号： A61Q19/00 , A01N31/06 , A61K8/34 , A61K31/075 , A61Q15/00 , A61Q17/005 , A01N49/00 , A01N2300/00
摘要： The present invention relates to an antibacterial composition containing a compound of formula I wherein R is a residue of the formula II and R is located at position 2, 3, or 6, and R1 is hydrogen; or R is located at position 4, and R1 is hydrogen or methoxy; or R is located at position 5, and R1 is methoxy. The present invention also relates to the use of the composition in personal care products and methods of making personal care products employing the composition. The antibacterial composition is active against Corynebacteria, Staphylococci, and Brevibacteria. It can therefore inhibit formation of different kinds of body malodor.
摘要翻译：本发明涉及含有式I化合物的抗菌组合物，其中R为式II的残基，R为位置2,3或6，R 1为氢; 或R为位置4，R 1为氢或甲氧基; 或R位于5位，R 1是甲氧基。本发明还涉及该组合物在个人护理产品中的用途以及使用该组合物制备个人护理产品的方法。抗菌组合物对Corynebacteria，Staphylococci和Brevibacteria具有活性。因此可以抑制不同种类的身体恶臭的形成。

23. 发明授权

US09440097B2 Organic compounds 有权
标题翻译：有机化合物
公开(公告)号：US09440097B2
公开(公告)日：2016-09-13
申请号：US13006791
申请日：2011-01-14
申请人： Andreas Natsch
发明人： Andreas Natsch , Michael Wasescha
IPC分类号： A61K8/33 , A61K8/37 , A61K8/40 , A61K31/275 , A61Q13/00 , A61Q15/00 , A61Q19/00
CPC分类号： A61K8/40 , A61K8/33 , A61K8/35 , A61K8/368 , A61K8/37 , A61K31/275 , A61K2800/75 , A61Q13/00 , A61Q15/00 , A61Q19/00
摘要： The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene; 2-methoxynaphthalene; 1-methoxy-4-(prop-1-enyl)benzene; 1-(cyclopropylmethyl)-4-methoxybenzene; wherein X, Y, and R1 to R11 have the same meaning as given in the description. Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.
摘要翻译：此外，本发明涉及用于局部施用于包含它们的皮肤的组合物。本发明还涉及减少或抑制皮肤刺激形成的方法。

24. 发明授权

US09192559B2 Compositions 有权
标题翻译：组合
公开(公告)号：US09192559B2
公开(公告)日：2015-11-24
申请号：US12518680
申请日：2007-12-11
申请人： Andreas Natsch
发明人： Andreas Natsch
IPC分类号： A61K8/33 , A61K8/49 , A61K8/92 , A61K8/02 , A61K31/11 , A01N35/04 , A61Q5/02 , A61Q15/00 , A61Q13/00 , A61Q19/00 , A01P3/00 , A61Q19/10 , A61K8/34
CPC分类号： A61K8/4973 , A01N35/04 , A61K8/33 , A61K8/345 , A61K8/347 , A61K2800/524 , A61Q19/00 , A01N31/02 , A01N2300/00
摘要： There are provided personal care products and compositions that comprise at least one diol compound selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 2-methyl-1,3-propandiol, and 3-(2-ethyl-hexyloxy)-1,2-propandiol in a total concentration of 0.1% to 0.5% (w/w); and at least one preservative enhancer compound selected from the group consisting of benzaldehyde, 4-methylbenzaldehyde, heliotropine, vanilline, 4-hydroxybenzaldehyde, 3-hydroxybenzaldehyde, 4-methoxybenzaldehyde and 3-methoxybenzaldehyde, 2,4-dihydroxybenzaldehyde, 3-hydroxy-4-methoxybenzaldehyde, 3,5-dihydroxybenzaldehyde, and 4-hydroxy-2-methoxybenzaldehyde, in a total concentration of 0.05 to 0.5% (w/w), in a cosmetically acceptable base. The composition optionally contains at least one compound selected from the group consisting of phenoxyethanol, 2-phenylethanol, and benzylalcohol, in a total concentration of 0.05 to 0.3% (w/w), but does not contain other classic bactericidal, fungicidal, sporicidal or preservative compounds. The invention is further directed to methods of forming such compositions and products and the use of preservatives and preservative enhancers in such compositions and products.
摘要翻译：提供了包含至少一种选自1,2-戊二醇，1,2-己二醇，1,2-辛二醇，2-甲基-1,3-丙二醇和二甲基-1,3-丙二醇的二醇化合物的个人护理产品和组合物，总浓度为0.1％至0.5％（w / w）的3-（2-乙基 - 己氧基）-1,2-丙二醇; 和至少一种选自苯甲醛，4-甲基苯甲醛，heliotropine，香草精，4-羟基苯甲醛，3-羟基苯甲醛，4-甲氧基苯甲醛和3-甲氧基苯甲醛，2,4-二羟基苯甲醛，3-羟基-4 - 甲氧基苯甲醛，3,5-二羟基苯甲醛和4-羟基-2-甲氧基苯甲醛，总浓度为0.05-0.5％（w / w），在化妆品可接受的碱中。该组合物任选地含有至少一种选自苯氧基乙醇，2-苯基乙醇和苄醇的化合物，其总浓度为0.05-0.3％（w / w），但不包含其它经典杀菌剂，杀真菌剂，杀孢子粉或防腐剂。本发明还涉及形成这种组合物和产品的方法以及在这种组合物和产品中使用防腐剂和防腐剂增强剂。

25. 发明申请

US20100284942A1 Compositions 有权
标题翻译：组合
公开(公告)号：US20100284942A1
公开(公告)日：2010-11-11
申请号：US12518680
申请日：2007-12-11
申请人： Andreas Natsch
发明人： Andreas Natsch
IPC分类号： A61K8/33 , A61K8/49 , A61K8/92 , A01N35/04 , A61K8/02 , A61K31/11 , A61Q5/02 , A61Q15/00 , A61Q13/00 , A61Q19/00 , A01P3/00 , A61Q19/10
CPC分类号： A61K8/4973 , A01N35/04 , A61K8/33 , A61K8/345 , A61K8/347 , A61K2800/524 , A61Q19/00 , A01N31/02 , A01N2300/00
摘要： There are provided personal care products and compositions that comprise at least one diol compound selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 2-methyl-1,3-propandiol, and 3-(2-ethyl-hexyloxy)-1,2-propandiol in a total concentration of 0.1% to 0.5% (w/w); and at least one preservative enhancer compound selected from the group consisting of benzaldehyde, 4-methylbenzaldehyde, heliotropine, vanilline, 4-hydroxybenzaldehyde, 3-hydroxybenzaldehyde, 4-methoxybenzaldehyde and 3-methoxybenzaldehyde, 2,4-dihydroxybenzaldehyde, 3-hydroxy-4-methoxybenzaldehyde, 3,5-dihydroxybenzaldehyde, and 4-hydroxy-2-methoxybenzaldehyde, in a total concentration of 0.05 to 0.5% (w/w), in a cosmetically acceptable base. The composition optionally contains at least one compound selected from the group consisting of phenoxyethanol, 2-phenylethanol, and benzylalcohol, in a total concentration of 0.05 to 0.3% (w/w), but does not contain other classic bactericidal, fungicidal, sporicidal or preservative compounds. The invention is further directed to methods of forming such compositions and products and the use of preservatives and preservative enhancers in such compositions and products.
摘要翻译：提供了包含至少一种选自1,2-戊二醇，1,2-己二醇，1,2-辛二醇，2-甲基-1,3-丙二醇和二甲基-1,3-丙二醇的二醇化合物的个人护理产品和组合物，总浓度为0.1％至0.5％（w / w）的3-（2-乙基 - 己氧基）-1,2-丙二醇; 和至少一种选自苯甲醛，4-甲基苯甲醛，heliotropine，香草精，4-羟基苯甲醛，3-羟基苯甲醛，4-甲氧基苯甲醛和3-甲氧基苯甲醛，2,4-二羟基苯甲醛，3-羟基-4 - 甲氧基苯甲醛，3,5-二羟基苯甲醛和4-羟基-2-甲氧基苯甲醛，总浓度为0.05-0.5％（w / w），在化妆品可接受的碱中。该组合物任选地含有至少一种选自苯氧基乙醇，2-苯基乙醇和苄醇的化合物，其总浓度为0.05-0.3％（w / w），但不包含其它经典杀菌剂，杀真菌剂，杀孢子粉或防腐剂。本发明还涉及形成这种组合物和产品的方法以及在这种组合物和产品中使用防腐剂和防腐剂增强剂。

26. 发明申请

US20090047223A1 Improvements in or Related to Organic Compoounds 审中-公开
标题翻译：有机化合物的改良或相关
公开(公告)号：US20090047223A1
公开(公告)日：2009-02-19
申请号：US12097896
申请日：2006-12-14
申请人： Andreas Natsch , Felix Flachsmann
发明人： Andreas Natsch , Felix Flachsmann
IPC分类号： A61K8/365 , C07C61/08 , A61P1/02
CPC分类号： C07C69/60 , A23G3/36 , A23G4/06 , A61K8/37 , A61K8/375 , A61K8/4973 , A61Q11/00 , C07C69/88 , C07C2601/14 , C11B9/0019 , C11B9/0034 , C11B9/0061 , C11B9/008
摘要： Malodour counteracting preparations for oral use comprising esterified fumarates of the formula (I) wherein X and Y have the same meaning as given in the description, is disclosed. Furthermore, the invention refers to a process for their preparation and to their use for preventing or reducing oral malodour.
摘要翻译：公开了包含式（I）的酯化的富马酸盐（其中X和Y具有与说明书中给出的含义相同的含义）的口服用Malodour抵消制剂。此外，本发明涉及其制备方法及其用于预防或减少口腔恶臭的用途。

27. 发明授权

US07459581B2 Anti-bacterial compounds 失效
标题翻译：抗菌化合物
公开(公告)号：US07459581B2
公开(公告)日：2008-12-02
申请号：US11661833
申请日：2005-08-31
申请人： Samuel Derrer , Andreas Natsch , Bernd Traupe , Melanie Stang
发明人： Samuel Derrer , Andreas Natsch , Bernd Traupe , Melanie Stang
IPC分类号： C07C229/00 , C07C69/66 , A61K31/22
CPC分类号： A01N37/36 , A01N37/44 , A61K8/37 , A61K8/416 , A61Q15/00 , A61Q17/005 , C07C69/675 , C07C229/08
摘要： Ester compounds of the formula I-a wherein R1 is selected from OH, NH2 and NH3+X−, wherein X is an inorganic anion, wherein R2 is a singly-branched saturated or unsaturated aliphatic hydrocarbon moiety selected from C7-C15, wherein R5 is selected from H, and a linear saturated or unsaturated aliphatic hydrocarbon moiety selected from C6-C14, and wherein R2 and R5 together have a total of 7 to 15 carbon atoms; that are useful as antibacterial or antifungal compounds in consumer products.
摘要翻译：式Ia的酯化合物，其中R1选自OH，NH2和NH3 + X-，其中X是无机阴离子，其中R2是选自C7-C15的单支链饱和或不饱和脂族烃部分，其中R5被选择来自H，和选自C 6 -C 14的线性饱和或不饱和脂族烃部分，并且其中R 2和R 5一起总共具有7至15个碳原子; 它们可用作消费品中的抗菌或抗真菌化合物。

28. 发明申请

US20080260659A1 Compositions 审中-公开
标题翻译：组合
公开(公告)号：US20080260659A1
公开(公告)日：2008-10-23
申请号：US12097979
申请日：2006-12-18
申请人： Andreas Natsch
发明人： Andreas Natsch
IPC分类号： A61K8/37 , A61K31/235 , A61P31/04 , A61K31/12
CPC分类号： A61K8/37 , A61K8/33 , A61K8/368 , A61K2800/524 , A61K2800/59 , A61Q17/005
摘要： The invention is directed to personal care products and compositions that comprise at least one preservative compound selected from the group consisting of benzoic acid, p-hydroxy-benzoic acid, methyl-paraben, ethyl-paraben, propyl-paraben, isopropyl-paraben, butyl-paraben, isobutyl-paraben, benzyl-paraben, or a salt thereof, in a total concentration of 0.1% to 0.5% (w/w); and at least one preservative enhancer compound selected from the group consisting of benzaldehyde, 4-methylbenzaldehyde, heliotropine, vanilline, 4-hydroxybenzaldehyde, 3-hydroxybenzaldehyde, 4-methoxybenzaldehyde, 3-methoxybenzaldehyde, 2,4-dihydroxybenzaldehyde, 3-hydroxy-4-methoxybenzaldehyde, 3,5-dihydroxybenzaldehyde, and 4-hydroxy-2-methoxybenzaldehyde, in a total concentration of 0.05 to 0.5% (w/w), in a cosmetically acceptable base. The composition optionally contains at least one compound selected from the group consisting of phenoxyethanol, 2-phenylethanol, and benzylalcohol, in a total concentration of 0.05 to 0.3% (w/w), but does not contain other classic bactericidal, fungicidal, sporicidal or preservative compounds. The invention is further directed to methods of forming such compositions and products and the use of preservatives and preservative enhancers in such compositions and products.
摘要翻译：本发明涉及个人护理产品和组合物，其包含至少一种选自苯甲酸，对羟基苯甲酸，对羟基苯甲酸甲酯，对羟基苯甲酸乙酯，对羟基苯甲酸丙酯，对羟基苯甲酸异丙酯，对羟基苯甲酸异丙酯，对羟基苯甲酸酯，异丁基对羟基苯甲酸酯，对羟基苯甲酸苄酯或其盐，总浓度为0.1％至0.5％（w / w）; 和至少一种选自苯甲醛，4-甲基苯甲醛，直链球蛋白，香草醛，4-羟基苯甲醛，3-羟基苯甲醛，4-甲氧基苯甲醛，3-甲氧基苯甲醛，2,4-二羟基苯甲醛，3-羟基-4 - 甲氧基苯甲醛，3,5-二羟基苯甲醛和4-羟基-2-甲氧基苯甲醛，总浓度为0.05-0.5％（w / w），在化妆品可接受的碱中。该组合物任选地含有至少一种选自苯氧基乙醇，2-苯基乙醇和苄醇的化合物，其总浓度为0.05-0.3％（w / w），但不包含其它经典杀菌剂，杀真菌剂，杀孢子粉或防腐剂。本发明还涉及形成这种组合物和产品的方法以及在这种组合物和产品中使用防腐剂和防腐剂增强剂。

29. 发明授权

US07402576B2 Phosphinic acid analogs of glutamate 失效
标题翻译：谷氨酸的次膦酸类似物
公开(公告)号：US07402576B2
公开(公告)日：2008-07-22
申请号：US10534528
申请日：2003-11-14
申请人： Fridtjof Schröder , Andreas Natsch
发明人： Fridtjof Schröder , Andreas Natsch
IPC分类号： A61K31/66 , C07F9/22
CPC分类号： C07F9/306 , C07F9/301 , C07F9/302
摘要： Inhibitors of axillary malodour having the formula wherein R has the same meaning as given in the specification.
摘要翻译：具有下式的腋窝恶臭抑制剂其中R具有与说明书中给出的相同的含义。

30. 发明申请

US20070276045A1 Anti-Bacterial Compounds 审中-公开
标题翻译：抗细菌化合物
公开(公告)号：US20070276045A1
公开(公告)日：2007-11-29
申请号：US11661852
申请日：2005-08-26
申请人： Samuel Derrer , Andreas Natsch , Bernd Traupe , Melanie Stang
发明人： Samuel Derrer , Andreas Natsch , Bernd Traupe , Melanie Stang
IPC分类号： A61K31/185 , A61P43/00
CPC分类号： A61Q17/005 , A61K8/36 , A61K8/37 , A61K8/44 , A61Q15/00 , C07C59/125 , C07C59/66 , C07C69/24 , C07C233/47 , C11D3/2075 , C11D3/33 , C11D3/48 , C11D7/265 , C11D7/3245
摘要： Acid compounds of formula I wherein Y is selected from O and NH, wherein X is selected from CO and CH2, and wherein R2 is a branched saturated or unsaturated hydrocarbon moiety selected from C7-C15, that are useful as antibacterial or antifungal compounds in consumer products.
摘要翻译：式I的酸化合物，其中Y选自O和NH，其中X选自CO和CH 2，并且其中R 2是选自C 7 -C 15的支链饱和或不饱和烃部分，其可用作消费者中的抗菌或抗真菌化合物产品。

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