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21. 发明授权

US5833619A External blood pressure sensor apparatus and method 失效
标题翻译：外部血压传感器装置及方法
公开(公告)号：US5833619A
公开(公告)日：1998-11-10
申请号：US856904
申请日：1997-05-15
申请人： Paul S. Freed , Adrian Kantrowitz
发明人： Paul S. Freed , Adrian Kantrowitz
IPC分类号： A61B5/0215 , A61B5/0456 , A61M1/10 , A61M1/12 , A61B5/00
CPC分类号： A61M1/1072 , A61B5/0215 , A61B5/0456
摘要： An apparatus and method for measuring the blood pressure of a patient with a permanent or temporary cardiac assist device throughout an entire cardiac cycle by partially filling the inflatable chamber of the cardiac assist device operatively disposed with respect to an aorta with pressurized fluid and using the partially filled chamber as a transducer. An external pressure sensor is located in a drive unit connected to the inflatable chamber. The drive unit controls, monitors and stores the fluid pressure with respect to the inflatable chamber. When isolated from a pressurized fluid reservoir, the pressure within the inflatable chamber corresponds to the current blood pressure of the patient throughout the cardiac cycle. The inflatable chamber preferably is defined at least in part by a flexible membrane. The inflatable chamber is partially inflated with a predetermined volume of pressurized fluid from the reservoir. The partially inflated chamber is then isolated from the reservoir for at least one complete cardiac cycle, and preferably two complete cardiac cycles. The blood pressure wave form of the patient is continuously monitored and stored by measuring the pressure variations in the isolated, partially filled, chamber. A control program evaluates the stored pressure data and updates a patient parameter table with current heart function parameters for subsequent use during the next series of diastolic augmentation, inflation/deflation cycles of the inflatable chamber.
摘要翻译：一种用于通过部分地填充相对于主动脉与加压流体可操作地设置的心脏辅助装置的可充气室来测量具有永久或临时心脏辅助装置的患者在整个心动周期中的血压的装置和方法，填充室作为传感器。外部压力传感器位于连接到可充气室的驱动单元中。驱动单元控制，监视和存储相对于可充气室的流体压力。当从加压流体储存器隔离时，可充气室内的压力对应于整个心脏周期中患者的当前血压。充气室优选至少部分地由柔性膜限定。充气室部分地从储存器中预定体积的加压流体充气。然后将部分充气的腔室与储器隔离至少一个完整的心动周期，优选两个完整心脏周期。通过测量隔离的，部分填充的腔室中的压力变化来连续监测和存储患者的血压波形。控制程序评估所存储的压力数据，并用当前的心脏功能参数来更新患者参数表，以便在下一系列舒张增压，充气室的充气/放气循环期间随后使用。

22. 发明授权

US4809681A Electrocardiographic measurement method for controlling an intra-aortic balloon pump 失效
标题翻译：用于控制主动脉内球囊泵的心电图测量方法
公开(公告)号：US4809681A
公开(公告)日：1989-03-07
申请号：US31137
申请日：1987-03-30
申请人： Adrian Kantrowitz , Paul S. Freed , Hiroyuki Tachi , Akira Suzuki
发明人： Adrian Kantrowitz , Paul S. Freed , Hiroyuki Tachi , Akira Suzuki
IPC分类号： A61B5/0215 , A61B5/042 , A61M1/10 , A61M29/02 , A61M1/00
CPC分类号： A61B5/6853 , A61B5/0215 , A61B5/042 , A61M1/1072 , A61M29/02
摘要： A pair of spaced electrodes are disposed inside the thoracic aorta near the heart and are used to sense R- and P-waves in an ECG signal. The electrodes are moved to an ideal intra-aortic position, which is that where R- and P-waves are sensed to have the same magnitude, the P-wave, which occurs earlier than the R-wave, serving as means for accurately predicting the occurrence of the R-wave. The electrodes are affixed to the distal end of an intra-aortic balloon, which is capable of being disposed at the ideal position by monitoring of the R- and P-waves sensed by the electrodes. The balloon is deflated at the occurrence of the R-wave, which has been correctly predicted by the earlier P-wave.
摘要翻译：一对间隔的电极设置在靠近心脏的胸主动脉内部，并用于感测ECG信号中的R波和P波。将电极移动到理想的主动脉内部位置，这是R和P波被感测到具有相同幅度的位置，P波早于R波发生，作为准确预测的手段发生R波。电极固定在主动脉内球囊的远端，该主动脉球囊能够通过监测由电极感测到的R-波和P波来放置在理想位置。在R波发生时气球被放气，这已经被较早的P波正确预测。

23. 发明授权

US4733652A Intra-aortic balloon 失效
标题翻译：主动脉内气囊
公开(公告)号：US4733652A
公开(公告)日：1988-03-29
申请号：US73843
申请日：1987-07-15
申请人： Adrian Kantrowitz , Paul S. Freed , Avi Bar-Lev , Sadahiko Mushika , Akira Suzuki
发明人： Adrian Kantrowitz , Paul S. Freed , Avi Bar-Lev , Sadahiko Mushika , Akira Suzuki
IPC分类号： A61M1/10 , A61B19/00
CPC分类号： A61M1/1072
摘要： An intra-aortic balloon pump apparatus includes a first catheter one end of which is secured to a connector having a gas supply port, a balloon one end of which is secured to the distal end of the first catheter, a central tubular member the distal end of which projects from the distal end of the first catheter and to which the distal end of the balloon is fixedly secured, a second catheter freely insertable into the central tubular member and having a distal end provided with an arterial pressure transduceer, and a second connector to which the other end of the second catheter is secured for feeding a signal from the pressure transducer to the outside of the apparatus. After the balloon, central tubular member and first catheter are placed into the aorta, the second catheter having the pressure transducer at its distal end is inserted through the interior of the central tubular member into the aorta.
摘要翻译：主动脉内球囊泵装置包括第一导管，其一端固定到具有气体供给口的连接器，其一端固定到第一导管的远端，中心管状构件的远端其中第一导管从第一导管的远端突出并且气囊的远端固定地固定到其上，第二导管可自由地插入中心管状构件中，并且具有设置有动脉压力变送器的远端，以及第二连接器固定第二导管的另一端用于将来自压力传感器的信号输送到装置的外部。在气囊之后，将中央管状构件和第一导管置于主动脉中，将具有其远端处的压力换能器的第二导管穿过中心管状构件的内部插入主动脉。

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