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21. 发明授权

US06869430B2 Tissue biopsy and treatment apparatus and method 失效
标题翻译：组织活检及治疗仪器及方法
公开(公告)号：US06869430B2
公开(公告)日：2005-03-22
申请号：US09823903
申请日：2001-03-30
申请人： Daniel J. Balbierz , Theodore Johnson
发明人： Daniel J. Balbierz , Theodore Johnson
IPC分类号： A61B10/00 , A61B1/00 , A61B10/02 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/00 , A61B18/12 , A61B18/14 , A61B19/00 , A61B18/18
CPC分类号： A61B18/1206 , A61B5/0071 , A61B10/02 , A61B10/0283 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1815 , A61B90/39 , A61B2017/00022 , A61B2017/00061 , A61B2017/003 , A61B2017/00849 , A61B2017/00867 , A61B2017/22082 , A61B2018/00029 , A61B2018/00083 , A61B2018/00142 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/0069 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/143 , A61B2018/1432 , A61B2018/1472 , A61B2018/1861 , A61B2090/064 , A61B2090/3782 , A61B2090/3941 , A61B2090/3966 , A61B2218/002 , A61N7/02 , C08L2201/12
摘要： An embodiment of the invention provides a tissue biopsy and treatment apparatus that comprises an elongated delivery device that is positionable in tissue and includes a lumen. A sensor array having a plurality of resilient members is deployable from the elongated delivery device. At least one of the plurality of resilient members is positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state. At least one of the plurality of resilient members includes at least one of a sensor, a tissue piercing distal end or a lumen. The sensor array has a geometric configuration adapted to volumetrically sample tissue at a tissue site to differentiate or identify tissue at the target tissue site. At least one energy delivery device is coupled to one of the sensor array, at least one of the plurality of resilient members or the elongated delivery device.
摘要翻译：本发明的一个实施例提供一种组织活检和治疗装置，其包括可定位在组织中并包括内腔的细长递送装置。具有多个弹性构件的传感器阵列可从细长的输送装置展开。多个弹性构件中的至少一个可以处于压实状态的细长递送装置中定位，并且在展开状态下可从细长的递送装置以曲率展开到组织中。多个弹性构件中的至少一个包括传感器，组织穿孔远端或管腔中的至少一个。传感器阵列具有适于在组织部位体积地采样组织以区分或识别靶组织部位的组织的几何构型。至少一个能量输送装置耦合到传感器阵列中的一个，多个弹性构件或细长输送装置中的至少一个。

22. 发明授权

US06216125B1 Coarse indexes for a data warehouse 失效
标题翻译：数据仓库的粗略索引
公开(公告)号：US06216125B1
公开(公告)日：2001-04-10
申请号：US09109516
申请日：1998-07-02
申请人： Theodore Johnson
发明人： Theodore Johnson
IPC分类号： G06F1730
CPC分类号： G06F17/30324 , Y10S707/99932 , Y10S707/99933 , Y10S707/99934 , Y10S707/99943
摘要： A coarse database index, and system and method of use therefor, that will quickly indicate which data partitions of a table contain a given key. Once the target data partitions are located, the exact record locations can be found using traditional indexes. The coarse indexes take little space, can be updated quickly, and searched quickly. The coarse index is in conjunction with a database including a plurality of data partitions. Each data partition includes data, including a plurality of key values of at least one key, and at least one dense index referencing the data. The coarse index indexing the plurality of key values according to data partitions containing each key value. The coarse index includes a first bitmap, which is preferably arranged in key value major format. The coarse index may also include a second bitmap, which is preferably arranged in data partition major format. The second bitmap may be transformed from data partition major format to key value major format. The first and second bitmap partitions may be compressed.
摘要翻译：粗略的数据库索引及其使用的系统和方法，将快速指示表的哪些数据分区包含给定的键。一旦找到目标数据分区，可以使用传统的索引找到确切的记录位置。粗略的索引空间很小，可以快速更新，快速搜索。粗略索引与包括多个数据分区的数据库相结合。每个数据分区包括数据，包括至少一个键的多个键值，以及引用该数据的至少一个密集索引。粗略索引根据包含每个键值的数据分区来索引多个键值。粗略索引包括优选地以键值主要格式布置的第一位图。粗略索引还可以包括优选地以数据分区主格式布置的第二位图。第二位图可以从数据分区主要格式转换为键值主要格式。可以压缩第一和第二位图分区。

23. 发明授权

US07805266B1 Method for automated detection of data glitches in large data sets 有权
标题翻译：用于自动检测大型数据集中的数据毛刺的方法
公开(公告)号：US07805266B1
公开(公告)日：2010-09-28
申请号：US09906104
申请日：2001-07-17
申请人： Tamraparni Dasu , Theodore Johnson
发明人： Tamraparni Dasu , Theodore Johnson
IPC分类号： G06F19/00 , G06F17/30
CPC分类号： G06F17/30507 , G06F17/30572
摘要： Embodiments of the invention allow the efficient detection of glitches in a set of data. In one embodiment, a set of datapoints is received. The datapoints are transformed into a transformed space, and the transformed space is segmented into a plurality of regions. For each datapoint, a time series is generated representing the trajectory of the transformed datapoint through regions of the segmented transformed space. Data corresponding to transformed datapoints whose trajectories exhibit an unusual pattern are transmitted.
摘要翻译：本发明的实施例允许有效地检测一组数据中的毛刺。在一个实施例中，接收一组数据点。将数据点变换为变换空间，将变换的空间分割为多个区域。对于每个数据点，生成表示通过分段变换空间的区域的经变换的数据点的轨迹的时间序列。发送对应于其轨迹呈现异常图案的变换数据点的数据。

24. 发明申请

US20070050371A1 Interacting with an online database through a variety of communications media 审中-公开
标题翻译：通过各种通信媒体与在线数据库进行交互
公开(公告)号：US20070050371A1
公开(公告)日：2007-03-01
申请号：US11213081
申请日：2005-08-26
申请人： Theodore Johnson , Peter Mullen , William Knight
发明人： Theodore Johnson , Peter Mullen , William Knight
IPC分类号： G06F17/30
CPC分类号： G06F16/972
摘要： A method for interacting with an online database through a variety of communications methods is described. Using e-mail programs, instant messaging applications, or SMS for mobile devices, a user of an online service composes and sends a language-based text message to an online service. A user services application implemented by the online service reads the incoming messages, verifies rights to the requested data, and determines whether the text message is a query or command. If the rights to the requested data have been confirmed by the mail reader application, the requested data is returned to the user in response to a query or the change is made to a record in the database in response to a command. In the case of e-mail, a confirmation step may be required in order to prevent spoofed e-mail commands.
摘要翻译：描述了通过各种通信方法与在线数据库交互的方法。使用电子邮件程序，即时消息应用程序或用于移动设备的SMS，在线服务的用户撰写并发送基于语言的短信到在线服务。由在线服务实现的用户服务应用程序读取传入消息，验证所请求数据的权限，并确定文本消息是查询还是命令。如果所请求的数据的权利已被邮件阅读器应用程序确认，则响应于查询而将所请求的数据返回给用户，或者响应于命令对数据库中的记录进行更改。在电子邮件的情况下，可能需要确认步骤以防止欺骗性的电子邮件命令。

25. 发明申请

US20060241577A1 Tissue biopsy and treatment apparatus and method 审中-公开
公开(公告)号：US20060241577A1
公开(公告)日：2006-10-26
申请号：US11338109
申请日：2006-01-23
申请人： Daniel Balbierz , Theodore Johnson
发明人： Daniel Balbierz , Theodore Johnson
IPC分类号： A61B18/18
CPC分类号： A61B18/1206 , A61B5/0071 , A61B10/02 , A61B10/0283 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1815 , A61B90/39 , A61B2017/00022 , A61B2017/00061 , A61B2017/003 , A61B2017/00849 , A61B2017/00867 , A61B2017/22082 , A61B2018/00029 , A61B2018/00083 , A61B2018/00142 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/0069 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/143 , A61B2018/1432 , A61B2018/1472 , A61B2018/1861 , A61B2090/064 , A61B2090/3782 , A61B2090/3941 , A61B2090/3966 , A61B2218/002 , A61N7/02 , C08L2201/12
摘要： A method of treating a tumor includes providing a tissue biopsy and treatment apparatus that includes an elongated delivery device that has a lumen and is maneuverable in tissue. A sensor array having a plurality of resilient members is deployable from the elongated delivery device. At least one of the plurality of resilient members is positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state. At least one of the plurality of resilient members includes at least one of a sensor, a tissue piercing distal end or a lumen. The sensor array has a geometric configuration adapted to volumetrically sample tissue at a tissue site to differentiate or identify tissue at the tissue site. At least one energy delivery device is coupled to one of the sensor array, at least one of the plurality of resilient members or the elongated delivery device. The apparatus is then introduced into a target tissue site. The sensor array is then utilized to distinguish a tissue type. The tissue type information derived from the sensor array is utilized to position the energy delivery device to ablate a tumor volume. Energy is then delivered from the energy delivery device to ablate or necrose at least a portion of the tumor volume. The sensor array is then utilized to determine an amount of tumor volume ablation.

26. 发明申请

US20060046966A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis 审中-公开
标题翻译：杀虫病毒化合物和组合物，其药物用途和用于其合成的材料
公开(公告)号：US20060046966A1
公开(公告)日：2006-03-02
申请号：US11210717
申请日：2005-08-24
申请人： Peter Dragovich , Stephen Webber , Thomas Prins , Ru Zhou , Joseph Marakovits , Theodore Johnson
发明人： Peter Dragovich , Stephen Webber , Thomas Prins , Ru Zhou , Joseph Marakovits , Theodore Johnson
IPC分类号： A61K38/04 , C07K5/04 , A61K31/433 , A61K31/4245
CPC分类号： C07D207/26 , A61K38/00 , C07D261/18 , C07D413/12 , C07K5/0205 , Y02A50/463 , Y02A50/465
摘要： Peptido and peptidomimetic compounds of the formula: wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.
摘要翻译：下式的肽和拟肽化合物：其中式变量如本公开所定义，有利地抑制或阻断小核糖核酸病毒3C蛋白酶的生物学活性。这些化合物以及含有这些化合物的药物组合物可用于治疗感染一种或多种微小核糖核酸病毒如RVP的患者或宿主。还提供了制备这些化合物的中间体和合成方法。

27. 发明授权

US06393516B2 System and method for storage media group parity protection 有权
标题翻译：存储介质组奇偶校验保护的系统和方法
公开(公告)号：US06393516B2
公开(公告)日：2002-05-21
申请号：US09852328
申请日：2001-05-10
申请人： Theodore Johnson
发明人： Theodore Johnson
IPC分类号： G06F1114
CPC分类号： G06F11/1076 , G06F2211/1019 , G06F2211/108
摘要： A system and method for storage medium group parity protection stores data files and related parity information asynchronously on an array of storage media. Data files can be stored asynchronously, or synchronously in stripes as in RAIT technology, but related parity information is stored asynchronously with respect to the data files. Regions of the storage media are preferably organized into protection groups for which parity information is generated. Parity information is generated on line as data files are stored and maintained in active memory. Once a protection group is filled, the parity information is migrated to more permanent backup storage. As one example, regions of an array of N storage media can constitute a protection group, and once the regions in the protection group are filled with data, parity data for the protection group is migrated from active memory to more permanent backup storage.
摘要翻译：用于存储介质组奇偶校验保护的系统和方法将数据文件和相关奇偶校验信息异步地存储在存储介质阵列上。数据文件可以像RAIT技术一样以异步方式或同步存储，但相关的奇偶校验信息相对于数据文件是异步存储的。存储介质的区域优选地被组织成产生奇偶校验信息的保护组。当数据文件被存储并保存在活动存储器中时，奇偶校验信息在线生成。一旦保护组被填满，奇偶校验信息将被迁移到更永久的备份存储。作为一个示例，N个存储介质阵列的区域可以构成保护组，并且一旦保护组中的区域被填充数据，保护组的奇偶校验数据将从活动存储器迁移到更永久的备份存储。

28. 发明授权

US06219800B1 Fault-tolerant storage system 失效
标题翻译：容错存储系统
公开(公告)号：US06219800B1
公开(公告)日：2001-04-17
申请号：US09100606
申请日：1998-06-19
申请人： Theodore Johnson , Dennis Shasha
发明人： Theodore Johnson , Dennis Shasha
IPC分类号： G06F1100
CPC分类号： G06F11/1076 , G06F2211/1059
摘要： The present invention is a storage system, and method of operation thereof, which provides improved performance over standard RAID-5 without increasing vulnerability to single-disk drive failures. The storage system comprises a processor and a plurality of data storage devices, coupled to the processor, operable to store a plurality of data stripes, each data stripe comprising a plurality of data blocks and a parity block, each data storage device operable to store one data block or the parity block of each data stripe. The storage system stores a dirty stripe bit vector of a data stripe. When an update to a data block in the data stripe is received, an image of the data block as it was when the dirty stripe bit vector was generated is stored. The data block is updated and an image of the updated data block is stored. When a failure of one of the plurality of data storage devices is detected, a bitwise exclusive-OR of the image of the data block as it was when the dirty stripe bit vector was generated and the image of the updated data block to form an intermediate result is generated. The parity block of the data stripe is read and a bitwise exclusive-OR of the intermediate result and the parity block is generated. The generated parity block is written and a parity rebuild is performed on the data stripe using the new parity block.
摘要翻译：本发明是一种存储系统及其操作方法，其提供比标准RAID-5更好的性能，而不增加对单磁盘驱动器故障的脆弱性。存储系统包括处理器和多个数据存储设备，耦合到处理器，可操作以存储多个数据条带，每个数据条带包括多个数据块和奇偶校验块，每个数据存储设备可操作以存储一个数据块或每个数据条带的奇偶校验块。存储系统存储数据条带的脏条带位向量。当接收到对数据条带中的数据块的更新时，存储当生成脏条带位向量时原始数据块的图像。更新数据块并存储更新的数据块的图像。当检测到多个数据存储装置中的一个的故障时，按照当生成脏条带位向量时的数据块的图像与更新后的数据块的图像进行按位异或以形成中间产生结果。读取数据条带的奇偶校验块，并生成中间结果和奇偶校验块的按位异或。所生成的奇偶校验块被写入，并且使用新的校验块在数据条带上执行奇偶校验。

29. 发明授权

US6055491A Method and apparatus for analyzing co-evolving time sequences 失效
标题翻译：用于分析共同演进的时间序列的方法和装置
公开(公告)号：US6055491A
公开(公告)日：2000-04-25
申请号：US953578
申请日：1997-10-17
申请人： Alexandros Biliris , Christos N. Faloutsos , Hosagrahar Visvesvaraya Jagadish , Theodore Johnson , Nikolaos Dimitrios Sidriopoulos , Byoung-Kee Yi
发明人： Alexandros Biliris , Christos N. Faloutsos , Hosagrahar Visvesvaraya Jagadish , Theodore Johnson , Nikolaos Dimitrios Sidriopoulos , Byoung-Kee Yi
IPC分类号： G06G7/02 , G06G7/19
CPC分类号： G06G7/02
摘要： An analyzer system that analyzes a plurality of co-evolving time sequences to, for example, perform correlation or outlier detection on the time sequences. The plurality of co-evolving time sequences comprise a delayed time sequence and one or more known time sequences. A goal is to predict the delayed value given the available information. The plurality of time sequences have a present value and (N-1) past values, where N is the number of samples (time-ticks) of each time sequence. The analyzer system receives the plurality of co-evolving time sequences and determines a window size ("w"). The analyzer then assigns the delayed time sequence as a dependent variable and the present value of a subset of the known time sequences, and the past values of the subset of known time sequences and the delayed time sequence, as a plurality of independent variables. Past values delayed by up to "w" steps are considered. The analyzer then forms an equation comprising the dependent variable and the independent variables, and then solves the equation using a least squares method. The delayed time sequence is then determined using the solved equation.
摘要翻译：分析系统，其分析多个共同演进的时间序列，以便例如对时间序列执行相关或异常值检测。多个共同演进的时间序列包括延迟时间序列和一个或多个已知时间序列。一个目标是预测给定可用信息的延迟值。多个时间序列具有当前值和（N-1）个过去值，其中N是每个时间序列的采样数（时间刻度）。分析器系统接收多个共同演进的时间序列并确定窗口大小（“w”）。然后，分析器将延迟的时间序列分配为因变量，将已知时间序列的子集的现值以及已知时间序列的子集的过去值和延迟的时间序列分配为多个独立变量。考虑到延迟最多为“w”步的过去值。然后，分析器形成包含因变量和独立变量的方程，然后使用最小二乘法求解方程。然后使用求解的方程确定延迟时间序列。

30. 发明授权

US09262504B2 Methods, systems, and products for maintaining data consistency in a stream warehouse 有权
标题翻译：用于维护流仓库数据一致性的方法，系统和产品
公开(公告)号：US09262504B2
公开(公告)日：2016-02-16
申请号：US13027486
申请日：2011-02-15
申请人： Lukasz Golab , Theodore Johnson
发明人： Lukasz Golab , Theodore Johnson
IPC分类号： G06F17/30
CPC分类号： G06F17/30371 , G06F17/30486 , G06F17/30516 , G06F17/30563 , G06F17/30592
摘要： Methods, systems, and products characterize consistency of data in a stream warehouse. A warehouse table is derived from a continuously received a stream of data. The warehouse table is stored in memory as a plurality of temporal partitions, with each temporal partition storing data within a contiguous range of time. A level of consistency is assigned to each temporal partition in the warehouse table.
摘要翻译：方法，系统和产品表示流仓库中数据的一致性。仓库表是从不断接收到的数据流导出的。仓库表作为多个时间分区存储在存储器中，每个时间分区将数据存储在连续的时间范围内。一个等级的一致性被分配给仓库表中的每个时间分区。

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